M. Bobek

发表

Integrating cancer genomics and proteomics in the post‐genome era

Rork Kuick, R. Kuick, S. Hanash, 2002, Proteomics.

Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis.

David E. Misek, R. Kuick, S. Hanash, 2001, Cancer research.

Synthesis of 5′-Fluoro-5′-deoxy-and 5′-Amino-5′-Deoxytoyocamycin and Sangivamycin and Some Related Derivatives

M. Ledvina, M. Bobek, Mahesh C Sharma, 1995 .

Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2.

R. Kuick, M. Ehrlich, S. Hanash, 2000, Human molecular genetics.

Acetylenic nucleosides. 4. 1-beta-D-arabinofuranosyl-5-ethynylcytosine. Improved synthesis and evaluation of biochemical and antiviral properties.

Y. Cheng, R. Sharma, M. Bobek, 1987, Journal of medicinal chemistry.

Influence of weather on the behaviour of reintroduced Przewalski’s horses in the Great Gobi B Strictly Protected Area (Mongolia): implications for conservation

M. Bobek, F. Ceacero, J. Šimek, 2022, BMC zoology.

Demonstration of viral thymidine kinase inhibitor and its effect on deoxynucleotide metabolism in cells infected with herpes simplex virus

Y. Cheng, R. Sharma, L. Nutter, 1987, Antimicrobial Agents and Chemotherapy.

Synthesis of 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-ethylnyl-1,2,3,4,-tetrahydropyrimidine-2,4-dione (5-ethynyl-2′-deoxyuridine)

R. Sharma, M. Bobek, J. Perman, 1976 .

Synthesis and biological activity of 5-fluoro-4'-thiouridine and some related nucleosides.

R. Whistler, M. Bobek, A. Bloch, 1975, Journal of medicinal chemistry.

Synthesis and biological activity of some imidazo[4,5-b]pyrazines and their ribonucleosides as purine analogs

R. Sharma, M. Bobek, A. Bloch, 1973 .

Cyano Sugars: Synthesis by Opening of an Epoxide Ring in Pentofuranosides with Diethylaluminum Cyanide

M. Bobek, Satoru Watanabe, I. Kavai, 1995 .

Methyl 3,4-di-O-acetyl-2-deoxy-2(R)-[1h,3h-2,4-dioxo-1-pyrimidinyl]-2-fluoro-β-D-arabinopyranoside: Novel nucleoside analogues via condensation of gem-2,2-difluoro methyl glycosides with silylated heterocyclic bases.

M. Bobek, S. An, 1986 .

Synthesis of 2′,3′-dideoxy-3′-methylene pyrimine nucleosides as potential anti-aids agents

M. Bobek, M. Sharma, 1990 .

THE CHEMISTRY AND BIOLOGY OF SOME NEW NUCLEOSIDE ANALOGS ACTIVE AGAINST TUMOR CELLS

M. Bobek, A. Bloch, 1978 .

Preparation and activity of the 4'-thio derivatives of some 6-substituted purine nucleosides.

R. Whistler, M. Bobek, A. Bloch, 1970, Journal of medicinal chemistry.

Synthesis and in vitro antitumor activity of some amino-deoxy 7-hexofuranosylpyrrolo[2,3-d]pyrimidines.

M. Bobek, B. G. Huang, 1998, Carbohydrate research.

Antiviral Action and Cellular Toxicity of Four Thymidine Analogues: 5-Ethyl-, 5-Vinyl-, 5-Propyl-, and 5-Allyl-2′-Deoxyuridine

R. Sharma, Y. Cheng, R. Sharma, 1976, Antimicrobial Agents and Chemotherapy.

Suppression of ocular herpes recurrences by a thymidine kinase inhibitor in squirrel monkeys.

Y. Cheng, H. Thompson, E. Varnell, 1991, Antiviral research.

ACETYLENIC NUCLEOSIDES. 1. SYNTHESIS OF 1-(5,6-DIDEOXY-β-D-RIBO-HEX-5-YNOFURANOSYL)URACIL AND 1-(2,5,6-TRIDEOXY-β-D-ERYTHRO-HEX-5-YNOFURANOSYL)-5-METHYLURACIL

R. Sharma, M. Bobek, 1978 .

Acetylenic nucleosides. 1. Synthesis of 1-(5,6-dideoxy-beta-D-ribo-hex-5-ynofuranosyl) uracil and 1-(2,5,6-Trideoxy-beta-D-erythro-hex-5-ynofuranosyl)-5-methyluracil.

R. Sharma, M. Bobek, 1978, The Journal of organic chemistry.

Synthesis of 3-(2-deoxy-β-{=D}--pentofuranosyl)-2,3-dihydro-1,3-6H-oxazine-2,6-dione (“3-oxa-2′-deoxyuridine”), a new pyrimidine nucleoside analog

S. Kuhar, M. Bobek, A. Bloch, 1973 .

2'-Fluorinated isonucleosides. 1. Synthesis and biological activity of some methyl 2'-deoxy-2'-fluoro-2'-pyrimidinyl-D-arabinopyranosides.

E. De Clercq, R. Bernacki, M. Bobek, 1989, Journal of Medicinal Chemistry.

A Practical Synthesis of The Antibiotic Toyocamycin

M. Bobek, A. Bloch, M. Sharma, 1993 .

Biological and biochemical effects of 2'-azido-2'-deoxyarabinofuranosylcytosine on human tumor cells in vitro.

R. S. Tan, Y. Cheng, D. Derse, 1981, Cancer research.

Novel arabinofuranosyl derivatives of cytosine resistant to enzymatic deamination and possessing potent antitumor activity.

Y. Cheng, M. Bobek, A. Bloch, 1978, Journal of medicinal chemistry.

2′-Azido-2′-deoxy- and 2′-amino-2′-deoxy-β-d-arabino-furanosyl purine nucleosides

M. Bobek, 1979 .

Preparation and biological activity of some aminoacyl and peptidyl derivatives of 2'-amino-2'-deoxyuridine.

R. Sharma, M. Bobek, A. Bloch, 1975, Journal of Medicinal Chemistry.

Synthesis of gem-difluorosaccharides

R. Sharma, M. Bobek, I. Kavai, 1977 .

Synthesis, biologic effects, and biochemical properties of some 2'-azido- and 2'-amino-2'-deoxyarabinofuranosyl pyrimidines and purines.

Y. Cheng, M. Bobek, E. Mihich, 1980, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

The synthesis of anomeric 3--acetyl-5--benzoyl-2-azido-2-deoxy--arabinofuranosyl chlorides. Versatile sugar intermediates for the synthesis of 2′-azido-2′-deoxy- and 2′-amino-2′-deoxy-β--arabinofuranosyl nucleosides.

V. Martín, M. Bobek, 1978 .

Synthesis and biological activity of 4'-thio analogs of the antibiotic toyocamycin.

R. Whistler, M. Bobek, A. Bloch, 1972, Journal of medicinal chemistry.

Relationship Between the Structure of Sangivamycin-Derived Nucleosides and Their Effect on Leukemic Cell Growth and on Protein Kinase A and C Activity

M. Bobek, A. Bloch, 1994 .

Synthesis and biological evaluation of 6-ethynyluracil, a thiol-specific alkylating pyrimidine.

M. Bobek, A. Schroeder, A. Bloch, 1982, Journal of Medicinal Chemistry.

Synthesis of 2′-amino-2′-deoxy-5-fluorocytidine

R. Sharma, M. Bobek, A. Bloch, 1982 .

Relationship Between the Structure of Sangivamycin‐Derived Nucleosides and Their Effect on Leukemic Cell Growth and on Protein Kinase A and C Activity.

M. Bobek, A. Bloch, 1995 .

Synthesis of 5′-Substituted Derivatives of the Pyrrolo[2,3-d]-Pyrimidine Nucleoside Sangivamycin and Their Effect on Protein Kinase A and C Activity

H. Wikiel, M. Bobek, R. Hromchak, 1993 .

Synthesis and biological activity of 2'-amino-2'-deoxy-5-fluorouridine.

R. Sharma, M. Bobek, A. Bloch, 1974, Journal of medicinal chemistry.

Synthesis and biological activity of 5-(2,2-difluorovinyl)-2'-deoxyuridine.

E. De Clercq, M. Bobek, I. Kavai, 1987, Journal of medicinal chemistry.

Synthesis and antitumor activity of 1,2-dihydro-1-(2-deosy-beta-D-erythro-pentofuranosyl)-2-oxo-5-methylpyrazine 4-oxide, a structural analogue of thymidine.

M. Bobek, J. Bardos, P. Berkowitz, 1977, Journal of medicinal chemistry.

An alternative synthesis of anomeric methyl 2-deoxy-4-thio-D-erythro-pentofuranosides.

M. Bobek, Y. L. Fu, 1976, The Journal of organic chemistry.

Synthesis of 5-vinyluridine and 5-vinyl-2'-deoxyuridine as new pyrimidine nucleoside analogs.

R. Sharma, M. Bobek, 1975, The Journal of organic chemistry.

Biochemical effects of 2'-azido-2'-deoxyarabinofuranosyl cytosine (cytarazid) in leukemia l1210 and hela cells. Abstr.

Y. Rustum, D. Derse, M. Bobek, 1980 .

NOVEL ARABINOFURANOSYL DERIVATIVES OF CYTOSINE RESISTANT TO ENZYMIC DEAMINATION AND POSSESSING POTENT ANTITUMOR ACTIVITY

M. Bobek, A. Bloch, Yung‐chi Cheng, 1978 .

PREPARATION AND BIOLOGICAL ACTIVITY OF SOME AMINOACYL AND PEPTIDYL DERIVATIVES OF 2′-AMINO-2′-DEOXYURIDINE

R. Sharma, M. Bobek, A. Bloch, 1976 .

Acetylenic nucleosides. 3. Synthesis and biological activities of some 5-ethynylpyrimidine nucleosides.

R. G. Hughes, R. Sharma, M. Bobek, 1984, Journal of medicinal chemistry.

Gliomas Based on Oligonucleotide Microarray Analysis Distinctive Molecular Profiles of High-Grade and Low-Grade Updated

David E. Misek, R. Kuick, S. Hanash, 2001 .

Pyrazine nucleoside analogs. Synthesis and reactions of some 5-thio-substituted pyrazines

M. Bobek, P. Tuntiwachwuttikul, T. Bardos, 1991 .

Synthesis and biological activity of 5-fluoro- and 5-methyl-1,3-oxazine-2,6(3H)-dione.

S. Kuhar, M. Bobek, A. Bloch, 1979, Journal of medicinal chemistry.

SYNTHESIS AND BIOLOGICAL ACTIVITY OF 5-FLUORO- AND 5-METHYL-1,3-OXAZINE-2,6(3H)-DIONE

S. Kuhar, M. Bobek, A. Bloch, 1979 .

Pyrazine Nucleoside Analogs. Synthesis and Reactions of Some 5‐ Thiosubstituted Pyrazines.

M. Bobek, P. Tuntiwachwuttikul, T. Bardos, 1991 .

Synthesis and biological activity of pyrazines and pyrazine ribonucleosides as pyrimidine analogs.

M. Bobek, A. Bloch, 1972, Journal of medicinal chemistry.

Beauty ranking of mammalian species kept in the Prague Zoo: does beauty of animals increase the respondents’ willingness to protect them?

D. Frynta, E. Landová, M. Janovcová, 2018, The Science of Nature.

African Odyssey project – satellite tracking of black storks Ciconia nigra breeding at a migratory divide

S. Bureš, M. Bobek, L. Peške, 2008 .

Food Provisioning and Nestling Diet of the Black Stork in the Czech Republic

P. Baláž, S. Bureš, M. Bobek, 2005 .

The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas.

David E. Misek, S. Hanash, M. Israel, 2001, Cancer research.

Symposium S05: Analysis of Movements

M. Bobek, L. Peške, P. Hulley, 2001 .

Dynamics of cervical langerhans cell counts in the course of HPV-positive CIN treatment with the use of human recombinant interferon gamma.

M. Bobek, M. Sikorski, T. Bieda, 2005, European journal of gynaecological oncology.

Use of factor IX complex in warfarin-related intracranial hemorrhage.

A. Schmaier, N. Boulis, J. Hoff, 1999, Neurosurgery.

Synthesis and biological activity of 5-fluoro-4'-thiouridine and some related nucleosides.

R. Whistler, M. Bobek, A. Bloch, 1975, Journal of medicinal chemistry.

Synthesis and in vitro antitumor activity of some amino-deoxy 7-hexofuranosylpyrrolo[2,3-d]pyrimidines.

M. Bobek, Bao-Guo Huang, 1998, Carbohydrate research.