N. Stewart

发表

Investigation of the Binding Specificity of Wild Type Human Platelet Profilin for Phosphatidylinositol-4, 5-bisphosphate (PIP2) and Analogues

N. Stewart, 2005 .

Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction

B. Chait, J. Berger, Yinyin Li, 2010, Proceedings of the National Academy of Sciences.

C6 Hydroxymethyl-Substituted Carbapenem MA-1-206 Inhibits the Major Acinetobacter baumannii Carbapenemase OXA-23 by Impeding Deacylation

M. Tóth, Clyde A. Smith, S. Vakulenko, 2022, mBio.

High affinity binding to profilin by a covalently constrained, soluble mimic of phosphatidylinositol-4,5-bisphosphate micelles.

N. Stewart, M. G. Oakley, Sarah M. Richer, 2009, ACS chemical biology.

NMR investigation of the binding between human profilin I and inositol 1,4,5-triphosphate, the soluble headgroup of phosphatidylinositol 4,5-bisphosphate.

M. Stone, N. Stewart, M. G. Oakley, 2008, Biochemistry.

Synthesis and characterization of covalent mimics of phosphatidylinositol-4,5-bisphosphate micelles.

Y. Mechref, M. Novotny, N. Stewart, 2007, Biomacromolecules.

The l,d-Transpeptidase LdtAb from Acinetobacter baumannii Is Poorly Inhibited by Carbapenems and Has a Unique Structural Architecture.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2022, ACS infectious diseases.

Class D β-Lactamases: Are They All Carbapenemases?

M. Tóth, S. Vakulenko, N. T. Antunes, 2014, Antimicrobial Agents and Chemotherapy.

Role of the Conserved Disulfide Bridge in Class A Carbapenemases*

M. Tóth, Clyde A. Smith, S. Vakulenko, 2016, The Journal of Biological Chemistry.

In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D β-lactamases.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2021, ACS infectious diseases.

Class D β-lactamases do exist in Gram-positive bacteria

Sergei Vakulenko, M. Tóth, Clyde A. Smith, 2015, Nature chemical biology.

Structural basis for carbapenemase activity of the OXA-23 β-lactamase from Acinetobacter baumannii.

Malika Kumarasiri, S. Mobashery, M. Tóth, 2013, Chemistry & biology.

Effects of Inactivation of d,d-Transpeptidases of Acinetobacter baumannii on Bacterial Growth and Susceptibility to β-Lactam Antibiotics

M. Tóth, S. Vakulenko, Mijoon Lee, 2021, Antimicrobial agents and chemotherapy.

Intrinsic Class D β-Lactamases of Clostridium difficile

M. Tóth, Clyde A. Smith, S. Vakulenko, 2018, mBio.

Aminoglycoside resistance profile and structural architecture of the aminoglycoside acetyltransferase AAC(6')-Im

M. Tóth, Clyde A. Smith, S. Vakulenko, 2017, Microbial cell.

Structural basis for the MukB‐topoisomerase IV interaction and its functional implications in vivo

J. Berger, N. Stewart, S. Vos, 2013, The EMBO journal.

A Synthetic Dual Drug Sideromycin Induces Gram-Negative Bacteria To Commit Suicide with a Gram-Positive Antibiotic.

W. Boggess, S. Vakulenko, Marvin J. Miller, 2018, Journal of medicinal chemistry.

Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type β-Lactamases

Clyde A. Smith, S. Vakulenko, Hilary Frase, 2014, Biochemistry.

Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases.

K. Kantardjieff, M. Tóth, Clyde A. Smith, 2015, ACS chemical biology.

Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D β-Lactamases

M. Tóth, Clyde A. Smith, S. Vakulenko, 2018, Antimicrobial Agents and Chemotherapy.

A Surface Loop Modulates Activity of the Bacillus Class D β-Lactamases.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2020, Journal of structural biology.

The Crystal Structures of CDD-1, the Intrinsic Class D β-Lactamase from the Pathogenic Gram-Positive Bacterium Clostridioides difficile, and its Complex with Cefotaxime.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2019, Journal of structural biology.

Structural Insights into the Mechanism of Carbapenemase Activity of the OXA-48 β-Lactamase

M. Tóth, Clyde A. Smith, S. Vakulenko, 2019, Antimicrobial Agents and Chemotherapy.

The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against Klebsiella spp. Isolates Producing OXA-48-Type Carbapenemases.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2023, ACS infectious diseases.

The role of conserved surface hydrophobic residues in the carbapenemase activity of the class D β-lactamases.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2017, Acta crystallographica. Section D, Structural biology.

Structural basis for the diversity of the mechanism of nucleotide hydrolysis by the aminoglycoside-2''-phosphotransferases.

M. Tóth, Clyde A. Smith, S. Vakulenko, 2019, Acta crystallographica. Section D, Structural biology.