H. Ngan

发表

Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells.

A. Cheung, N. Auersperg, L. W. Cheung, 2006, Endocrinology.

Patient compliance with cervical smear surveillance in a shared‐care setting

P. Ip, A. Cheung, H. Ngan, 2016, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Hypermethylation of SOX2 Gene in Hydatidiform Mole and Choriocarcinoma

E. Wong, H. Ngan, A. Cheung, 2008, Reproductive Sciences.

Proto-oncogenes and p53 protein expression in normal cervical stratified squamous epithelium and cervical intra-epithelial neoplasia.

A. Cheung, H. Ngan, H. Yu, 1999, European journal of cancer.

Title Differential DNA methylation profiles in gynecological cancersand correlation with clinico-pathological data

Vincent WS Liu, H. Ngan, Hui-juan Yang, 2006 .

Differential Functions of Growth Factor Receptor–Bound Protein 7 (GRB7) and Its Variant GRB7v in Ovarian Carcinogenesis

D. Chan, V. W. Liu, H. Ngan, 2010, Clinical Cancer Research.

Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface

H. Lai, P. Ip, A. Cheung, 2018, Nature Communications.

Aberrant upregulation of PDK1 in ovarian cancer cells impairs CD8+ T cell function and survival through elevation of PD-L1

M. K. Siu, A. Cheung, D. Chan, 2019, Oncoimmunology.

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.

Wei Zheng, Weiqun Peng, Yan Kai, 2018, Cancer letters.

Loss of Programmed cell death 4 (Pdcd4) associates with the progression of ovarian cancer

A. Cheung, Thomas H. Leung, X. Liao, 2009, Molecular Cancer.

Overexpressed PAK4 promotes proliferation, migration and invasion of choriocarcinoma.

A. Cheung, Hongquan Zhang, H. Ngan, 2011, Carcinogenesis.

p21-Activated kinase-1 promotes aggressive phenotype, cell proliferation, and invasion in gestational trophoblastic disease.

A. Cheung, D. S. Kong, H. Ngan, 2010, The American journal of pathology.

p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells.

A. Cheung, A. Wong, H. Ngan, 2008, Cancer research.

FBI-1 Is Overexpressed in Gestational Trophoblastic Disease and Promotes Tumor Growth and Cell Aggressiveness of Choriocarcinoma via PI3K/Akt Signaling.

Ka-Kui Chan, E. Wong, A. Cheung, 2015, The American journal of pathology.

Downregulation of ASPP2 in choriocarcinoma contributes to increased migratory potential through Src signaling pathway activation.

Xin Lu, A. Cheung, H. Ngan, 2013, Carcinogenesis.

Section B: Malignant manifestations of HPV infection Carcinoma of the cervix, vulva, vagina, anus, and penis

L. Denny, H. Ngan, 2006, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer

L. Chow, I. Andrulis, H. Ozçelik, 1999, Oncogene.

Pazopanib Maintenance Therapy in East Asian Women With Advanced Epithelial Ovarian Cancer: Results From AGO-OVAR16 and an East Asian Study

Jae-Weon Kim, Ji-Hong Liu, Byoung-Gie Kim, 2015, International Journal of Gynecologic Cancer.

Who receives, benefits from and is harmed by cervical and breast cancer screening among Hong Kong Chinese?

B. Cowling, T. Lam, G. Leung, 2008, Journal of public health.

Functional polymorphisms in the BRCA1 promoter influence transcription and are associated with decreased risk for breast cancer in Chinese women

J. Long, W. Zheng, U. Khoo, 2008, Journal of Medical Genetics.

Comparison of Human Papillomavirus DNA Levels in Gynecological Cancers: Implication for Cancer Development

A. Cheung, V. W. Liu, H. Ngan, 2003, Tumor Biology.

Establishment and characterization of a human first-trimester extravillous trophoblast cell line (TEV-1).

S. Tsao, A. Cheung, W. Deng, 2005, Journal of the Society for Gynecologic Investigation.

Orchestrated Action of AMPK Activation and Combined VEGF/PD-1 Blockade with Lipid Metabolic Tunning as Multi-Target Therapeutics against Ovarian Cancers

M. K. Siu, D. Chan, H. Ngan, 2022, International journal of molecular sciences.

The Potential Molecular Therapeutic Approach in Targeting Ovarian Clear Cell Carcinoma

D. Chan, H. Ngan, 2012 .

Title Increased expression of PITX 2 transcription factor contributes toovarian cancer progression

A. Cheung, D. Chan, V. W. Liu, 2012 .

Abnormal expression or mutation of TP53 and HPV in vulvar cancer.

A. Cheung, H. Ngan, S. Liu, 1999, European journal of cancer.

maximum likelihood and Bayesian methods incidence in Hong Kong from 1972 to 2001 using Age-period-cohort analysis of cervical cancer

G. Leung, T. Thach, S. McGhee, 2006 .

The need for public education on HPV and cervical cancer prevention in Asia. Opinions of experts at the AOGIN conference.

M. Pitts, S. Pagliusi, C. J. Chen, 2008, Vaccine.

Human papillomavirus-16/18 AS04-adjuvanted cervical cancer vaccine: immunogenicity and safety in healthy Chinese women from Hong Kong.

A. Cheung, H. Tang, D. Descamps, 2010, Hong Kong medical journal = Xianggang yi xue za zhi.

Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance

Noel Southall, P. Shinn, Wei Zheng, 2018, Oncogene.

Association between High Diffusion-Weighted Imaging-Derived Functional Tumor Burden of Peritoneal Carcinomatosis and Overall Survival in Patients with Advanced Ovarian Carcinoma

E. Hui, H. Ngan, J. A. Perucho, 2022, Korean journal of radiology.

SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells

D. Chan, H. Ngan, Y. Chan, 2021, Theranostics.

Update on the diagnosis and management of gestational trophoblastic disease

R. Berkowitz, M. Seckl, L. Massuger, 2018, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Update on the diagnosis and management of gestational trophoblastic disease

R. Berkowitz, M. Seckl, H. Ngan, 2018, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Tyrosine kinase B receptor and BDNF expression in ovarian cancers - Effect on cell migration, angiogenesis and clinical outcome.

E. Wong, A. Cheung, X. Liao, 2009, Cancer letters.

Downregulation of ASPP1 in gestational trophoblastic disease: correlation with hypermethylation, apoptotic activity and clinical outcome

Xin Lu, A. Cheung, H. Ngan, 2011, Modern Pathology.

A comprehensive systematic review and network meta-analysis: the role of anti-angiogenic agents in advanced epithelial ovarian cancer

R. Kennedy, R. Ngan, H. Ngan, 2021, Scientific Reports.

Gestational trophoblastic disease.

H. Ngan, K. Tse, 2003, Best practice & research. Clinical obstetrics & gynaecology.

Trophoblastic disease

L. Cole, R. Kurman, M. Seckl, 2012, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Management of early cervical cancer

H. Ngan, Karen K. L. Chan, 2014 .

Telomerase Assay and HPV 16/18 Typing as Adjunct to Conventional Cytological Cervical Cancer Screening

S. Tsao, A. Cheung, H. Ngan, 2002, Tumor Biology.

Primary treatment with vincristine, dactinomycin, and cyclophosphamide in nondysgerminomatous germ cell tumor of the ovary.

H. Ngan, H. Ma, L. Wong, 1989, Gynecologic oncology.

Aberrant activation of hedgehog signaling pathway in ovarian cancers: Effect on prognosis, cell invasion and differentiation

A. Cheung, X. Liao, H. Ngan, 2008 .

MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis.

Dakang Xu, Jinbiao Zhan, T. Ng, 2020, Pharmacological research.

Assessment of knowledge and stigmatizing attitudes related to human papillomavirus among Hong Kong Chinese healthcare providers

H. Ngan, K. Chan, K. Tam, 2012, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Anti-fibrotic effect of decorin in peritoneal dialysis and PD-associated peritonitis

K. Chu, T. Chan, S. Yung, 2020, EBioMedicine.

Title Paradoxical Impact of Two Folate Receptors , FR α and RFC , in Ovarian Cancer : Effect on Cell Proliferation , Invasion and Clinical Outcome

P. Ip, A. Cheung, X. Le, 2014 .

Early detection of persistent trophoblastic tumour by serum human chorionic gonadotrophin monitoring after molar pregnancy.

H. Ngan, L. Wong, 1999, Chinese medical journal.

Title Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer

Thomas H. Leung, D. Chan, H. Ngan, 2013 .

Down-regulation of Sox7 is associated with aberrant activation of Wnt/β-catenin signaling in endometrial cancer

Thomas H. Leung, D. Chan, H. Ngan, 2012, Oncotarget.

New Insights into Ferroptosis Initiating Therapies (FIT) by Targeting the Rewired Lipid Metabolism in Ovarian Cancer Peritoneal Metastases

M. K. Siu, D. Chan, H. Ngan, 2022, International journal of molecular sciences.

Prognostic significance of serum tumour markers in carcinoma of the cervix.

I. Lauder, A. Cheung, H. Ngan, 1996, European journal of gynaecological oncology.

Control of cervical cancer: Women's options and rights

J. Cain, S. Garland, H. Ngan, 2009, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Overcoming barriers to the eradication of cervical cancer: Women's health and rights

J. Cain, L. Denny, H. Ngan, 2007, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Post‐treatment serial serum squamous cell carcinoma antigen (SCC) in the monitoring of squamous cell carcinoma of the cervix

H. Ngan, H. Ma, L. Wong, 1996 .

The prognostic value of TPA and SCC in squamous cell carcinoma of the cervix.

W. Yeung, H. Ngan, H. Ma, 1994, Gynecologic oncology.

Serum squamous cell carcinoma antigen in the monitoring of radiotherapy treatment response in carcinoma of the cervix.

D. Choy, S. Chan, H. Ngan, 1990, Gynecologic oncology.

Use of serum squamous cell carcinoma antigen assays in chemotherapy treatment of cervical cancer.

S. Chan, H. Ngan, H. Ma, 1989, Gynecologic oncology.

The Impact of the Tumor Microenvironment on Macrophage Polarization in Cancer Metastatic Progression

D. Chan, H. Ngan, Karen K. L. Chan, 2021, International journal of molecular sciences.

Staging and classification systems 1 6 STAGING AND CLASSIFICATION SYSTEMS

H. Ngan, L. Wong, K. Tse, 2016 .

The practicability of FIGO 2000 staging for gestational trophoblastic neoplasia.

H. Ngan, 2004, International journal of gynecological cancer : official journal of the International Gynecological Cancer Society.

Overexpression of NANOG in gestational trophoblastic diseases: effect on apoptosis, cell invasion, and clinical outcome.

A. Cheung, H. Ngan, M. Siu, 2008, The American journal of pathology.

Malignant mixed Müllerian tumors of the uterus

H. Ngan, W. To, 1994, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

BRCA1 deficiency induces protective autophagy to mitigate stress and provides a mechanism for BRCA1 haploinsufficiency in tumorigenesis.

Ava Kwong, A. Cheung, W. Xia, 2014, Cancer letters.

Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer

K. Yao, D. Chan, P. Chiu, 2014, Molecular Cancer.

Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers

E. Lam, A. Cheung, X. Le, 2013, Oncogene.

Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications

D. Chan, P. Chiu, H. Ngan, 2012, BMC Cancer.

miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer

Weiqun Peng, Yan Kai, A. Tzatsos, 2018, Oncogene.

Tumor-secreted exosomal miR-141 activates tumor-stroma interactions and controls premetastatic niche formation in ovarian cancer metastasis

M. K. Siu, S. Tsui, Dakang Xu, 2023, Molecular Cancer.

Transforming growth factor beta1 promotes chromosomal instability in human papillomavirus 16 E6E7-infected cervical epithelial cells.

S. Tsao, E. Wong, A. Cheung, 2008, Cancer research.

Domestic Violence in Hong Kong Chinese Women Attending Colposcopy Clinics

H. Ngan, K. Tam, W. Paulin, 2011 .

ERK Regulates HIF1α-Mediated Platinum Resistance by Directly Targeting PHD2 in Ovarian Cancer

Wei Zheng, A. Cheung, Wei Sun, 2019, Clinical Cancer Research.

Persistent gestational trophoblastic disease after a diploid partial hydatidiform mole coexisting with a normal living fetus.

H. Ngan, A. Ghosh, N. A. Cheung, 1992, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

The practicability of FIGO 2000 staging for gestational trophoblastic neoplasia

H. Ngan, 2004, International Journal of Gynecologic Cancer.

Relapsed gestational trophoblastic neoplasia: A 20-year experience.

H. Ngan, K. Chan, K. Lam, 2006, The Journal of reproductive medicine.

Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

Hui-Juan Yang, Vincent WS Liu, Yue Wang, 2006, BMC Cancer.

Overexpression of proto-oncogene FBI-1 activates membrane type 1-matrix metalloproteinase in association with adverse outcome in ovarian cancers

E. Lam, A. Cheung, X. Le, 2010, Molecular Cancer.

Extremely stringent activation of p16INK4a prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression

S. Tsao, A. Cheung, W. Deng, 2016, Oncotarget.

Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells.

T. Furukawa, K. Yao, D. Chan, 2008, Carcinogenesis.

Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation

P. Ip, E. Wong, A. Cheung, 2008, Carcinogenesis.

Targeting AMPK signaling in combating ovarian cancers: opportunities and challenges.

D. Chan, H. Ngan, M. Yung, 2016, Acta biochimica et biophysica Sinica.

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade

F. Ross, D. Hardie, Jinbiao Zhan, 2015, Integrative cancer therapies.

Title Bitter melon ( Momordica charantia ) extract functions as a natural AMPK activator and synergistically enhances cisplatin cytotoxicity in ovarian cancer cells

F. Ross, D. Hardie, Jinbiao Zhan, 2016 .

The mitosis‐specific marker phosphohistone‐H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumours: an outcome‐based study

P. Ip, A. Cheung, C. Cheung, 2017, Histopathology.

Asia Oceania Guidelines for the Implementation of Programs for Cervical Cancer Prevention and Control

Y. Qiao, E. Domingo, S. Garland, 2011, Journal of cancer epidemiology.

Review Article Asia Oceania Guidelines for the Implementation of Programs for Cervical Cancer Prevention and Control 1. Aogin Consensus Statement on Prevention and Control of Cervical Cancer

Y. Qiao, E. Domingo, S. Garland, 2022 .

Title Reduced expression of AMPK-β 1 during tumor progressionenhances the oncogenic capacity of advanced ovarian cancer

K. Yao, D. Chan, P. Chiu, 2014 .

Aberrant activation of hedgehog signaling pathway contributes to endometrial carcinogenesis through β-catenin

P. Ip, A. Cheung, X. Liao, 2009, Modern Pathology.

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

S. Tsao, A. Cheung, S. Strömblad, 2010, Proceedings of the National Academy of Sciences.

International survey on fear and childbirth experience in pregnancy and the postpartum period during the COVID-19 pandemic: study protocol

M. Tarrant, D. Fong, H. Ngan, 2021, BMJ Open.

p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation

A. Cheung, D. S. Kong, Lili Jiang, 2015, PloS one.

Vacuum Extractor: A Safe Instrument?

H. Ngan, H. Ma, G. Tang, 1986, The Australian & New Zealand journal of obstetrics & gynaecology.

Germline PALB2 Mutation in High-Risk Chinese Breast and/or Ovarian Cancer Patients

T. Chan, C. Au, A. Kwong, 2021, Cancers.

Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells

K. Yao, D. Chan, V. W. Liu, 2011, PloS one.

Mechanisms of Chemoresistance in Human Ovarian Cancer at a Glance

D. Chan, H. Ngan, M. Liu, 2012 .

Germline Mutation in 1338 BRCA-Negative Chinese Hereditary Breast and/or Ovarian Cancer Patients

T. Chan, C. Au, A. Kwong, 2020, The Journal of Molecular Diagnostics.

Germline mutation in 1,338 BRCA-negative Chinese hereditary breast and/or ovarian cancer patients: clinical testing with a multigene test panel.

E. Ma, T. Chan, C. Au, 2020, The Journal of molecular diagnostics : JMD.

Mutational analysis of BRCA1 and BRCA2 genes in Chinese ovarian cancer identifies 6 novel germline mutations

Jing Lu, I. Andrulis, H. Ozçelik, 2000, Human mutation.

Role of adjuvant and post-surgical treatment in gynaecological cancer.

H. Ngan, Karen K. L. Chan, Siew-Fei Ngu, 2021, Best practice & research. Clinical obstetrics & gynaecology.

TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies.

M. von Knebel Doeberitz, M. Blettner, A. Giuliano, 2009, The Lancet. Oncology.

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

M. K. Siu, H. Ngan, H. Ngan, 2018, Cancer Cell International.

Title Aberrant activation of ERK / FOXM 1 signaling cascade triggersthe cell migration / invasion in ovarian cancer cells

D. Chan, V. W. Liu, H. Ngan, 2011 .

Staging of uterine sarcomas.

R. Crawford, H. Ngan, K. Tse, 2011, Best practice & research. Clinical obstetrics & gynaecology.

Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells

K. Yao, D. Chan, H. Ngan, 2011, The Journal of pathology.

Verification of HPV16 as a good prognostic factor for cervical adeno-adenosquamous carcinoma via an international collaborative study.

Lan-Yan Yang, Cheng-Chang Chang, Shih-Ming Jung, 2022, Taiwanese journal of obstetrics & gynecology.

Nuclear HKII-P-p53 (Ser15) Interaction is a Prognostic Biomarker for Chemoresponsiveness and Glycolytic Regulation in Epithelial Ovarian Cancer

M. K. Siu, Y. Song, R. Bast, 2021, Cancers.

Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis

Tak-Hong Cheung, So Fan Yim, David I. Smith, 2005, Oncogene.

Overexpression of Forkhead Box Protein M1 (FOXM1) in Ovarian Cancer Correlates with Poor Patient Survival and Contributes to Paclitaxel Resistance

E. Lam, A. Cheung, A. Gomes, 2014, PloS one.

MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis

Kai-Fai Lee, D. Chan, H. Ngan, 2017, Molecular Cancer.

miR-135a leads to cervical cancer cell transformation through regulation of β-catenin via a SIAH1-dependent ubiquitin proteosomal pathway.

S. Tsao, A. Cheung, W. Yeung, 2014, Carcinogenesis.

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer

D. Chan, H. Ngan, M. Siu, 2013, Oncotarget.

Title Epigenetic silencing of microRNA-199 b-5 p is associated with acquired chemoresistance via activation of JAG 1-Notch 1 signaling in ovarian cancer

D. Chan, H. Ngan, M. Siu, 2014 .

Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels

L. Esserman, A. Kurian, S. Domchek, 2017, Oncotarget.

HPV 16 E2 binding sites 1 and 2 become more methylated than E2 binding site 4 during cervical carcinogenesis

A. Cheung, H. Ngan, T. Leung, 2015, Journal of medical virology.

MicroRNA-135a-induced formation of CD133+ subpopulation with cancer stem cell properties in cervical cancer.

S. Tsao, A. Cheung, W. Yeung, 2020, Carcinogenesis.

Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers

D. Chan, H. Ngan, K. Chan, 2021, Clinical Epigenetics.

Robotic Natural Orifice Transluminal Endoscopic Surgery Hysterectomy and Salpingo-Oophorectomy in a Porcine Model

C. Yeung, B. Sreedhar, H. Ngan, 2021, Surgical innovation.

Dysregulated stemness-related genes in gynecological malignancies.

A. Cheung, H. Ngan, M. Siu, 2012, Histology and histopathology.

SENP1-mediated deSUMOylation of JAK2 regulates its kinase activity and platinum drug resistance

Wei Zheng, A. Cheung, Huadong Pei, 2021, Cell Death & Disease.

Increased Expression of PITX2 Transcription Factor Contributes to Ovarian Cancer Progression

A. Cheung, D. Chan, V. W. Liu, 2012, PloS one.

Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival

A. Cheung, X. Le, Lili Jiang, 2011, Histopathology.

Mitochondrial DNA variant 16189T>C is associated with susceptibility to endometrial cancer

P. Nagley, V. W. Liu, H. Ngan, 2003, Human mutation.

Age-period-cohort analysis of cervical cancer incidence in Hong Kong from 1972 to 2001 using maximum likelihood and Bayesian methods

T. Thach, S. McGhee, G. Leung, 2006, Journal of Epidemiology and Community Health.

Paradoxical Impact of Two Folate Receptors, FRα and RFC, in Ovarian Cancer: Effect on Cell Proliferation, Invasion and Clinical Outcome

P. Ip, A. Cheung, X. Le, 2012, PloS one.

Aberrant Cholesterol Metabolism in Ovarian Cancer: Identification of Novel Therapeutic Targets

M. K. Siu, H. Ngan, K. Chan, 2021, Frontiers in Oncology.

Long‐term Neurological Sequelae Following Vacuum Extractor Delivery

H. Ngan, L. Ko, H. Ma, 1990, The Australian & New Zealand journal of obstetrics & gynaecology.

Epigenetic Silencing of miR-33b Promotes Peritoneal Metastases of Ovarian Cancer by Modulating the TAK1/FASN/CPT1A/NF-κB Axis

Xueyu Wang, D. Chan, H. Ngan, 2021, Cancers.

Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface

H. Lai, P. Ip, A. Cheung, 2018, Nature Communications.

Targeting estrogen-related receptor alpha inhibits epithelial-to-mesenchymal transition and stem cell properties of ovarian cancer cells.

A. Cheung, A. Wong, H. Ngan, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Somatic mutation profiling in BRCA-negative breast and ovarian cancer patients by multigene panel sequencing.

Dona N. Ho, E. Ma, T. Chan, 2020, American journal of cancer research.

Further study of sexual functioning following treatment of carcinoma of the cervix in Chinese patients

H. Ngan, G. Tang, 1988 .

Vaginal template implant for cervical carcinoma with vaginal stenosis or inadvertent diagnosis after hysterectomy.

D. Choy, J. Sham, H. Ngan, 1994, International journal of radiation oncology, biology, physics.

P634A4 and TAp73 immunocytochemistry in liquid-based cervical cytology—potential biomarkers for diagnosis and progress prediction of cervical neoplasia

A. Cheung, H. Ngan, M. Siu, 2010, Modern Pathology.

PFKFB3 Regulates Chemoresistance, Metastasis and Stemness via IAP Proteins and the NF-κB Signaling Pathway in Ovarian Cancer

A. Cheung, D. Chan, H. Ngan, 2022, Frontiers in Oncology.

Loss of MKP3 is associated with cisplatin-resistance and tumorigenicity of ovarian cancer

D. Chan, V. W. Liu, H. Ngan, 2007 .

Molecular Biomarkers for the Early Detection of Ovarian Cancer

M. K. Siu, H. Ngan, K. Chan, 2022, International journal of molecular sciences.

Tumour Markers and Their Prognostic Value in Adenocarcinoma of the Cervix

I. Lauder, A. Cheung, H. Ngan, 1998, Tumor Biology.

Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells

Dakang Xu, D. Chan, H. Ngan, 2019, Communications Biology.

iASPP and Chemoresistance in Ovarian Cancers: Effects on Paclitaxel-Mediated Mitotic Catastrophe

Lara J. Monteiro, E. Lam, Xin Lu, 2011, Clinical Cancer Research.

Title MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF 12 / Sp 1 / survivin axis

Kai-Fai Lee, D. Chan, H. Ngan, 2017 .

Patient-Initiated Follow-Up in Ovarian Cancer

H. Ngan, K. Chan, K. Tse, 2023, Current oncology.

De‐stigmatising human papillomavirus in the context of cervical cancer: a randomised controlled trial

H. Ngan, K. Chan, K. Tam, 2010, Psycho-oncology.

P-cadherin cooperates with insulin-like growth factor-1 receptor to promote metastatic signaling of gonadotropin-releasing hormone in ovarian cancer via p120 catenin

P. Leung, L. W. Cheung, A. Wong, 2011, Oncogene.

The increase of mitochondrial DNA content in endometrial adenocarcinoma cells: a quantitative study using laser-captured microdissected tissues.

A. Cheung, V. W. Liu, H. Ngan, 2005, Gynecologic oncology.

Cervical Cancer Burden and Prevention Strategies: Asia Oceania Perspective

S. Garland, H. Ngan, N. Bhatla, 2012, Cancer Epidemiology, Biomarkers & Prevention.

Maternal transfer of anti HPV 6 and 11 antibodies upon immunization with the 9-valent HPV vaccine

A. Hirschberg, O. Bautista, A. Luxembourg, 2018, Human vaccines & immunotherapeutics.

Role of CA125 and abdominal pelvic computerized axial tomogram in the monitoring of chemotherapy treatment of ovarian cancer.

S. Chan, H. Ngan, L. Wong, 1990, Cancer Investigation.

Human papillomavirus infection in the cervix of pregnant females in Hong Kong

G. Srivastava, A. Cheung, T. Pun, 1990, Cytopathology : official journal of the British Society for Clinical Cytology.

The Stress-Inducible BCL2A1 Is Required for Ovarian Cancer Metastatic Progression in the Peritoneal Microenvironment

D. Chan, H. Ngan, K. Chan, 2021, Cancers.

Radiomic Features of T2-weighted Imaging and Diffusion Kurtosis Imaging in Differentiating Clinicopathological Characteristics of Cervical Carcinoma.

P. Ip, V. Vardhanabhuti, H. Ngan, 2021, Academic radiology.

Title p 21-Activated Kinases 1 , 2 and 4 in Endometrial Cancers : Effectson Clinical Outcomes and Cell Proliferation

Y. Cheung, D. S. Kong, Lili Jiang, 2015 .

Pazopanib (Paz) monotherapy in Asian women who have not progressed after first-line chemotherapy for advanced ovarian, Fallopian tube, or primary peritoneal carcinoma.

M. Yen, Byoung-Gie Kim, Lihui Wei, 2013 .

Abnormal expression of pan-ras, c-myc and tp53 in squamous cell carcinoma of cervix: correlation with HPV and prognosis.

A. Cheung, H. Ngan, L. Wong, 2001, Oncology reports.

Detection of human papillomavirus DNA in malignant lesions from Chinese women with carcinomas of the upper genital tract.

A. Cheung, A. Cheung, H. Ngan, 2002, Gynecologic oncology.

Mutational analysis of BRCA1 and BRCA2 genes in Chinese ovarian cancer identifies 6 novel germline mutations

I. Andrulis, H. Ozçelik, A. Cheung, 2000, Human mutation.

FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology.

H. Ngan, J. Benedet, S. Pecorelli, 2000, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Detection of hypermethylated genes in tumor and plasma of cervical cancer patients.

A. Cheung, U. Khoo, H. Ngan, 2004, Gynecologic oncology.

E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours.

H. Ngan, H. Ngan, L. Wong, 2003, European journal of cancer.

DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling

H. Ngan, Dakang Xu, B. Tsang, 2016, Oncogene.

Assessment of cell proliferation in hydatidiform mole using monoclonal antibody MIB1 to Ki-67 antigen.

H. Ngan, A. Cheung, A. Cheung, 1994, Journal of clinical pathology.

Effect of all-trans retinoic acid on tissue dynamics of choriocarcinoma cell lines: an organotypic model

S. Tsao, H. Ngan, A. Cheung, 2006, Journal of Clinical Pathology.

Frequent Occurrence of Mitochondrial Microsatellite Instability in the D‐Loop Region of Human Cancers

P. Nagley, H. Ngan, Yue Wang, 2005, Annals of the New York Academy of Sciences.

p70 S6 kinase in the control of actin cytoskeleton dynamics and directed migration of ovarian cancer cells

H. Ngan, C. Ip, A. Wong, 2011, Oncogene.

Recurrent BRCA1 and BRCA2 germline mutations in ovarian cancer: A founder mutation of BRCA1 identified in the Chinese population

K. Choy, H. Ozçelik, H. Ngan, 2002, Human mutation.

Quantification of human papillomavirus DNA in the plasma of patients with cervical cancer

H. Ngan, V. W. Liu, H. Ngan, 2004, International Journal of Gynecologic Cancer.

Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells

Dakang Xu, D. Chan, H. Ngan, 2019, Communications Biology.

Loss of imprinting of the IGF-II and H19 genes in epithelial ovarian cancer.

H. Ngan, H. Ngan, L. Wong, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas.

A. Cheung, P. Nagley, T. Leung, 2001, Cancer research.

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer

D. Chan, H. Ngan, M. Siu, 2013, Oncotarget.

t(High) frequency of telomeric associations in human ovarian surface epithelial cells transformed by human papilloma viral oncogenes.

S. Tsao, H. Ngan, L. Chan, 1997, Cancer genetics and cytogenetics.

Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease.

H. Ngan, E. Wong, Ky Wong, 2008, Placenta.

Gestational trophoblastic disease.

H. Ngan, K. Tse, 2012, Best practice & research. Clinical obstetrics & gynaecology.

Clinical applicability of the ATP cell viability assay as a predictor of chemoresponse in platinum-resistant epithelial ovarian cancer using nonsurgical tumor cell samples.

H. Ngan, H. Ngan, L. Wong, 2000, Gynecologic oncology.

Primary HPV testing with cytology versus cytology alone in cervical screening—A prospective randomized controlled trial with two rounds of screening in a Chinese population

H. Ngan, H. Ngan, S. Liu, 2020, International journal of cancer.

Methylation profile in benign, borderline and malignant ovarian tumors

H. Ngan, A. Cheung, V. W. Liu, 2007, Journal of Cancer Research and Clinical Oncology.

Efficacy, Immunogenicity, and Safety of a 9-Valent Human Papillomavirus Vaccine: Subgroup Analysis of Participants From Asian Countries

S. Garland, P. Pitisuttithum, H. Yoshikawa, 2018, The Journal of infectious diseases.

Trophoblastic disease

L. Cole, R. Kurman, M. Seckl, 2012, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Association of decreased mitochondrial DNA content with ovarian cancer progression

A. Cheung, H. Ngan, V. W. Liu, 2006, British Journal of Cancer.

Outcome after loop electrosurgical excision procedure for cervical high-grade squamous intraepithelial lesion.

H. Ngan, Siew-Fei Ngu, L. S. Lau, 2023, Taiwanese journal of obstetrics & gynecology.

A4. Preinvasive lesions of the cervix

H. Ngan, C. Trimble, 2006, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Dose-tumor response of carcinoma of cervix: an analysis of 594 patients treated by radiotherapy.

J. Sham, D. Choy, H. Ngan, 1993, Gynecologic oncology.