B. Shane

发表

Biomarkers of Nutrition for Development-Folate Review.

M. Fenech, L. Bailey, H. McNulty, 2015, The Journal of nutrition.

Primary structure of the Escherichia coli folC gene and its folylpolyglutamate synthetase-dihydrofolate synthetase product and regulation of expression by an upstream gene.

A. Bognar, B. Shane, C. Osborne, 1987, The Journal of biological chemistry.

Folylpoly-γ-glutamate synthesis by bacteria and mammalian cells

B. Shane, D. J. Cichowicz, S. K. Foo, 1981, Molecular and Cellular Biochemistry.

Effect of nicotinic acid administration on hepatic very low density lipoprotein-triglyceride production.

S. Myong, M. Hellerstein, R. Neese, 2001, American journal of physiology. Endocrinology and metabolism.

A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin.

Alexander F. Wilson, A. F. Wilson, H. Abaan, 2016, American journal of human genetics.

The Dihydrofolate Reductase 19 bp Polymorphism Is Not Associated with Biomarkers of Folate Status in Healthy Young Adults, Irrespective of Folic Acid Intake.

E. Gibney, A. Parle‐McDermott, L. Brody, 2015, The Journal of nutrition.

Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.

M. Brosnan, J. Brosnan, E. Gibney, 2015, The Journal of nutrition.

Common Variants at Putative Regulatory Sites of the Tissue Nonspecific Alkaline Phosphatase Gene Influence Circulating Pyridoxal 5'-Phosphate Concentration in Healthy Adults.

Alexander F. Wilson, A. F. Wilson, E. Gibney, 2015, The Journal of nutrition.

Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status?

J. Troendle, E. Gibney, P. Ueland, 2011, The American journal of clinical nutrition.

Role of folylpolyglutamate synthetase in the metabolism and cytotoxicity of 5-deazaacyclotetrahydrofolate, an anti-purine drug.

J. S. Kim, B. Shane, 1994, The Journal of biological chemistry.

In silico experimentation with a model of hepatic mitochondrial folate metabolism

H. Nijhout, C. Ulrich, M. Reed, 2006, Theoretical Biology and Medical Modelling.

Biomarkers of folate status in NHANES : a roundtable summary 1 – 6

L. Curtin, J. Massaro, C. Sempos, 2011 .

Biomarkers of folate status in NHANES: a roundtable summary123456

L. Curtin, J. Massaro, C. Sempos, 2011, The American journal of clinical nutrition.

Cell and stage of transformation-specific effects of folate deficiency on methionine cycle intermediates and DNA methylation in an in vitro model.

J. Stempak, K. Sohn, Young-In Kim, 2005, Carcinogenesis.

Regulation of folate and one-carbon metabolism in mammalian cells. III. Role of mitochondrial folylpoly-gamma-glutamate synthetase.

B. Shane, B. Lin, R. Huang, 1993, The Journal of biological chemistry.

Expression cloning of a human cDNA encoding folylpoly(gamma-glutamate) synthetase and determination of its primary structure.

A. Admon, B. Shane, T. Garrow, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Expression of Escherichia coli folylpolyglutamate synthetase in the Chinese hamster ovary cell mitochondrion.

B. Shane, B. Lin, 1994, The Journal of biological chemistry.

Folate-responsive birth defects: of mice and women.

B. Shane, 2012, The American journal of clinical nutrition.

Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficiency or excess. Part I – Folate, Vitamin B12, Vitamin B6

L. Bailey, W. Holzgreve, J. Simpson, 2010, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

Excess on Cancer-Related Biomarkers Mathematical Modeling Predicts the Effect of Folate Deficiency and Updated

H. Nijhout, C. Ulrich, M. Reed, 2011 .

Functionally null mutations in patients with the cblG-variant form of methionine synthase deficiency.

D. Leclerc, D. Rosenblatt, J. Phillips, 1998, American journal of human genetics.

Accumulation of 5‐methyltetrahydrofolic acid and folylpolyglutamate synthetase expression by mitogen stimulated human lymphocytes

S. Weitman, R. Lark, D. Fort, 1993, British journal of haematology.

Purification and Properties of Human Cytosolic Folylpoly-γ-glutamate Synthetase and Organization, Localization, and Differential Splicing of Its Gene*

J. Korenberg, B. Shane, Yun-Jung Choi, 1996, The Journal of Biological Chemistry.

Rapid Decline in Folylpolyglutamate Synthetase Activity and Gene Expression during Maturation of HL-60 Cells

B. Rumberger, F. Sirotnak, B. Rumberger, 1995, Journal of Biological Chemistry.

Different Antifolate-resistant L1210 Cell Variants with either Increased or Decreased Folylpolyglutamate Synthetase Gene Expression at the Level of mRNA Transcription (*)

F. Sirotnak, K. Roy, B. Shane, 1995, The Journal of Biological Chemistry.

Folylpoly-γ-Glutamate Synthetase

Yunjung Choi, P. Stover, B. Shane, 1993 .

Mammalian folylpoly-gamma-glutamate synthetase. 1. Purification and general properties of the hog liver enzyme.

B. Shane, D. J. Cichowicz, 1987, Biochemistry.

In situ autoradiographic detection of folylpolyglutamate synthetase activity.

D. Sussman, B. Shane, C. Osborne, 1986, Analytical biochemistry.

Characterization of human folylpolyglutamate synthetase expressed in Chinese hamster ovary cells

D. Sussman, B. Shane, G. Milman, 1986, Somatic cell and molecular genetics.

Regulation of folylpoly-gamma-glutamate synthesis in bacteria: in vivo and in vitro synthesis of pteroylpoly-gamma-glutamates by Lactobacillus casei and Streptococcus faecalis

A. Bognar, J. Lebowitz, B. Shane, 1983, Journal of bacteriology.

Folate bioavailability in humans: effects of wheat bran and beans.

B. Shane, S. M. Oace, P. Keagy, 1988, The American journal of clinical nutrition.

Characterization of the coexisting multiple mechanisms of methotrexate resistance in mouse 3T6 R50 fibroblasts.

Y. Assaraf, R. Schimke, J. Feder, 1992, The Journal of biological chemistry.

Enhancement of biological activity by conjugation reactions.

C. Fenselau, M. W. Anders, B. Shane, 1992, The Journal of nutrition.

Molecular Cloning, Characterization, and Regulation of the Human Mitochondrial Serine Hydroxymethyltransferase Gene*

K. Keyomarsi, P. Stover, Jae Rin Suh, 1997, The Journal of Biological Chemistry.

Chemistry and Biology of Pteridines and Folates

R. Levine, S. Milstien, G. Kapatos, 2002, Springer US.

Is low iron status a risk factor for neural tube defects?

L. Brody, J. Mills, R. Fan, 2014, Birth defects research. Part A, Clinical and molecular teratology.

Micronutrients and women of reproductive potential: required dietary intake and consequences of dietary deficienty or excess. Part II - Vitamin D, Vitamin A, Iron, Zinc, Iodine, Essential Fatty Acids

L. Bailey, W. Holzgreve, J. Simpson, 2011, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.

P. Ueland, L. Brody, J. Mills, 2016, The Journal of nutrition.

Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization.

X. Chen, J. Korenberg, B. Shane, 1993, The Journal of biological chemistry.

Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population

J. Troendle, L. Brody, A. Molloy, 2011, American journal of medical genetics. Part A.

Folate metabolism in the ethanol-fed rat.

B. Shane, J. Wilkinson, 1982, The Journal of nutrition.

Targeted Disruption of the Methionine Synthase Gene in Mice

M. Stitzel, L. Brody, L. Garrett, 2001, Molecular and Cellular Biology.

Quantitative analysis of folylpolyglutamate synthetase gene expression in tumor tissues by the polymerase chain reaction: marked variation of expression among leukemia patients.

H. Lenz, J. Bertino, K. Danenberg, 1994, Oncology research.

Folylpolyglutamates in Leishmania major.

D. Santi, B. Shane, P. Nolan, 1987, Biochemical and biophysical research communications.

Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metabolism.

J. S. Kim, B. Shane, C. Osborne, 1993, The Journal of biological chemistry.

Purification and properties of Lactobacillus casei folylpoly-gamma-glutamate synthetase.

A. Bognar, B. Shane, 1983, The Journal of biological chemistry.

Pteroylpoly(gamma-glutamate) synthesis by Corynebacterium species. In vivo synthesis of folates.

B. Shane, 1980, The Journal of biological chemistry.

Regulation of Folate-mediated One-carbon Metabolism by 10-Formyltetrahydrofolate Dehydrogenase*

J. Selhub, P. Stover, M. C. Anguera, 2006, Journal of Biological Chemistry.

Folate fortification: enough already? 1,2

B. Shane, 2003 .

Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia.

G. Morgan, C. Skibola, S. Rollinson, 2002, Blood.

[50] Identification of folylpoly(γ-glutamate) chain length by cleavage to and separation of p-aminobenzoylpoly(γ-glutamates)

B. Shane, 1986 .

Identification of glutamine chain lengths of endogenous Folypoly-γ-glytamates in rat tissues

B. Shane, D. Schutz, J. Watson, 1977 .

Radiometric--microbiologic assay of vitamin B-6: application to food analysis.

T. Guilarte, B. Shane, P. McIntyre, 1981, The Journal of nutrition.

Mthfd1 Is an Essential Gene in Mice and Alters Biomarkers of Impaired One-carbon Metabolism*

P. Stover, A. MacFarlane, B. Shane, 2009, Journal of Biological Chemistry.

Inhibition of hog liver folylpolyglutamate synthetase by 5-substituted 5,8-dideaza analogues of folic acid bearing a terminal L-ornithine residue.

B. Shane, S. Singh, J. Hynes, 1992, Journal of Medicinal Chemistry.

Summary and Future Directions for Epidemiological, Preventive and Basic Research

A. Motulsky, S. Fortmann, B. Shane, 2000 .

Biomarkers of vitamin B-12 status in NHANES: a roundtable summary

L. Curtin, J. Massaro, C. Sempos, 2011, The American journal of clinical nutrition.

Folic Acid and L-5-Methyltetrahydrofolate

L. Bailey, B. Shane, K. Pietrzik, 2010, Clinical pharmacokinetics.

Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase. Cloning and high expression of the Escherichia coli folC gene and purification and properties of the gene product.

R. Ferone, A. Bognar, B. Shane, 1985, The Journal of biological chemistry.

Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop.

C. Davis, I. Rosenberg, R. Finnell, 2020, The American journal of clinical nutrition.

Regulation of folylpoly-gamma-glutamate synthesis in mammalian cells. In vivo and in vitro synthesis of pteroylpoly-gamma-glutamates by Chinese hamster ovary cells.

B. Shane, S. K. Foo, 1982, The Journal of biological chemistry.

High performance liquid chromatography of folates: identification of poly-gamma-glutamate chain lengths of labeled and unlabeled folates.

B. Shane, 1982, The American journal of clinical nutrition.

Cleavage of naturally occurring folates to unsubstituted p-aminobenzoylpoly-gamma-glutamates.

B. Shane, D. J. Cichowicz, S. K. Foo, 1980, Analytical biochemistry.

Folate status assessment history: implications for measurement of biomarkers in NHANES12345

B. Shane, 2011, The American journal of clinical nutrition.

FOLATE CHEMISTRY AND METABOLISM*

B. Shane, 2001 .

Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.

K. Shelnutt, L. Bailey, J. Shuster, 2005, The Journal of nutrition.

Cerebral Vascular Dysfunction in Methionine Synthase–Deficient Mice

A. Devlin, T. Bottiglieri, F. Faraci, 2004, Circulation.

Inhibition of mammalian folylpolyglutamate synthetase and human dihydrofolate reductase by 5,8-dideaza analogues of folic acid and aminopterin bearing a terminal L-ornithine.

B. Shane, S. Singh, J. Freisheim, 1989, Journal of medicinal chemistry.

Substrate specificity of mammalian folylpoly-gamma-glutamate synthetase for 5,8-dideazafolates and 5,8-dideaza analogues of aminopterin.

B. Shane, J. Hynes, D. J. Cichowicz, 1988, Biochimica et biophysica acta.

Mammalian folylpoly-gamma-glutamate synthetase. 3. Specificity for folate analogues.

B. Shane, D. J. Cichowicz, S. George, 1987, Biochemistry.

Mammalian folylpoly-gamma-glutamate synthetase. 2. Substrate specificity and kinetic properties.

B. Shane, D. J. Cichowicz, 1987, Biochemistry.

Folylpoly-gamma-glutamate synthesis by bacteria and mammalian cells.

B. Shane, D. J. Cichowicz, S. K. Foo, 1981, Molecular and cellular biochemistry.

Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism.

B. Shane, 1989, Vitamins and hormones.

leukemia hydroxymethyltransferase genes and risk of adult acute lymphocytic Polymorphisms in the thymidylate synthase and serine

G. Morgan, C. Skibola, S. Rollinson, 2013 .

Cytoplasmic Serine Hydroxymethyltransferase Mediates Competition between Folate-dependent Deoxyribonucleotide andS-Adenosylmethionine Biosyntheses*

Katherine L. Herbig, P. Stover, B. Shane, 2002, The Journal of Biological Chemistry.

Bioinformatic and Genetic Association Analysis of MicroRNA Target Sites in One-Carbon Metabolism Genes

P. Sethupathy, P. Ueland, L. Brody, 2011, PloS one.

Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L.

T. Hudson, B. Ge, T. Wai, 2002, American journal of human genetics.

Human Methionine Synthase

B. Shane, H. Hwang, Linda H. Chen, 1997, The Journal of Biological Chemistry.

New and underutilized technologies to reduce maternal mortality: call to action from a Bellagio workshop

B. Shane, V. Tsu, V D Tsu, 2004, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Impaired milk folate secretion is not corrected by supplemental folate during iron deficiency in rats.

D. O’Connor, B. Shane, T. Tamura, 1990, The Journal of nutrition.

Absorption of mono- and polyglutamyl folates in zinc-depleted man.

J. King, E. Stokstad, S. Margen, 1978, The American journal of clinical nutrition.

Availability of monoglutamyl and polyglutamyl folates in normal subjects and in patients with coeliac sprue.

B. Shane, A. Reisenauer, T. Tamura, 1978, Gut.

Synthesis and biological evaluation of analogues of 5,8-dideazaisofolic acid (IAHQ) modified at positions 2, 4 and 9.

B. Shane, J. Freisheim, J. Hynes, 1993, Advances in experimental medicine and biology.

Synthesis and preliminary biological evaluation of analogues of 5,8-dideazaisofolic acid and its 2-desamino-2-methyl derivative containing fluorine at position five.

B. Shane, J. Freisheim, J. Hynes, 1993, Advances in experimental medicine and biology.

Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects

P. Chines, J. Troendle, A. Parle‐McDermott, 2012, BMC Medical Genetics.

Regulation of folate and one-carbon metabolism in mammalian cells. I. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-gamma-glutamate synthetase activity.

B. Shane, C. Osborne, K. Lowe, 1993, Journal of Biological Chemistry.

Mammalian folylpoly-gamma-glutamate synthetase. 4. In vitro and in vivo metabolism of folates and analogues and regulation of folate homeostasis.

B. Shane, D. J. Cichowicz, A. Lawler, 1987, Biochemistry.

Folylpoly-gamma-glutamate synthetase: generation of isozymes and the role in one carbon metabolism and antifolate cytotoxicity.

Y. Choi, S. Xiao, H. Qi, 1999, Advances in enzyme regulation.

Molecular biology in nutrition research: modeling of folate metabolism.

J. S. Kim, B. Shane, T. Garrow, 1996, Advances in food and nutrition research.

Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice.

R. Rozen, R. Finnell, L. Brody, 2007, The Journal of nutritional biochemistry.

Mathematical Modeling of Folate Metabolism: Predicted Effects of Genetic Polymorphisms on Mechanisms and Biomarkers Relevant to Carcinogenesis

H. Nijhout, C. Ulrich, M. Reed, 2008, Cancer Epidemiology Biomarkers & Prevention.

Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

A. Evans, D. Shields, J. Yarnell, 1999, Genetic epidemiology.

Evolution of drug resistance in CCRF-CEM human leukemia cells selected by intermittent methotrexate exposure.

B. Shane, J. McGuire, C. Russell, 1995, Oncology research.

The 677C→T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population.

A. F. Wilson, J. Bailey-Wilson, P. Ueland, 2018, The American journal of clinical nutrition.

Serine Hydroxymethyltransferase Anchors de Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis*

P. Stover, B. Shane, C. Woeller, 2012, The Journal of Biological Chemistry.

Serine Hydroxymethyltransferase Anchorsde Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA

P. Stover, B. Shane, C. Woeller, 2012 .

Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor.

L. Bailey, J. Gregory, E. Quinlivan, 2004, American journal of physiology. Endocrinology and metabolism.

In vitro metabolism of 5,8-dideazafolates and 5,8-dideazaisofolates by mammalian folylpoly-gamma-glutamate synthetase.

D. Cesar, B. Shane, J. Hynes, 1991, Biochemical pharmacology.

Glutamate carboxypeptidase II and folate deficiencies result in reciprocal protection against cognitive and social deficits in mice: Implications for neurodevelopmental disorders

J. Coyle, L. Schaevitz, J. Berger-Sweeney, 2012, Developmental neurobiology.

Vitamin B-6 metabolism and turnover in the ethanol-fed rat.

B. Shane, 1982, The Journal of nutrition.

Human Mitochondrial C1-Tetrahydrofolate Synthase

D. Appling, B. Shane, Schuyler T. Pike, 2003, Journal of Biological Chemistry.

Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosides.

K. Shelnutt, L. Bailey, J. Gregory, 2005, The Journal of nutrition.

Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.

R. Strawderman, A. Litonjua, J. Gaziano, 2005, The Journal of nutrition.

Effect of methotrexate and 5-fluorouracil on de novo thymidylate synthesis in human colon carcinoma cell line, Caco-2

Sang-Woon Choi, J. Selhub, B. Shane, 1996 .

Folate and Vitamin B12 Metabolism: Overview and Interaction with Riboflavin, Vitamin B6, and Polymorphisms

B. Shane, 2008, Food and nutrition bulletin.

Human cytosolic folylpoly-γ-glutamate synthase

B. Shane, T. Garrow, I. Atkinson, 1997 .

Isolation of dihydrofolate and folylpolyglutamate synthetase activities from Neurospora.

B. Shane, E. Cossins, I. Atkinson, 1995, Phytochemistry.

Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid.

M. Hanlon, B. Shane, J. Freisheim, 1991, Biochemical pharmacology.

A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.

Barry Shane, Cornelia M Ulrich, H Frederik Nijhout, 2006, The Journal of nutrition.

Folic Acid and L-5-Methyltetrahydrofolate Comparison of Clinical Pharmacokinetics and Pharmacodynamics

L. Bailey, B. Shane, K. Pietrzik, 2010 .

Human cytosolic folylpoly-gamma-glutamate synthase.

B. Shane, T. Garrow, I. Atkinson, 1997, Methods in enzymology.

Regulation of folate and one-carbon metabolism in mammalian cells. IV. Role of folylpoly-gamma-glutamate synthetase in methotrexate metabolism and cytotoxicity.

J. S. Kim, B. Shane, K. Lowe, 1993, The Journal of biological chemistry.

Folinate Supplementation Ameliorates Methotrexate Induced Mitochondrial Formate Depletion In Vitro and In Vivo

Yi-Ming Chen, Der-Yuan Chen, B. Shane, 2021, International journal of molecular sciences.

Mathematical Modeling Predicts the Effect of Folate Deficiency and Excess on Cancer-Related Biomarkers

Barry Shane, Cornelia M Ulrich, H Frederik Nijhout, 2011, Cancer Epidemiology, Biomarkers & Prevention.

Biomarkers of vitamin B-12 status in NHANES: a roundtable summary123456

L. Curtin, J. Massaro, C. Sempos, 2011, The American journal of clinical nutrition.

Supplemental folic acid.

B. Shane, M. Zimmermann, 1993, The American journal of clinical nutrition.

Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.

J. Toth, J. Gregory, P. Stacpoole, 2000, The American journal of clinical nutrition.

Combined marginal folate and riboflavin status affect homocysteine methylation in cultured immortalized lymphocytes from persons homozygous for the MTHFR C677T mutation.

J. Selhub, P. Bagley, V. Shih, 2003, The Journal of nutrition.

Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults.

M. Brosnan, J. Brosnan, P. Ueland, 2018, The American journal of clinical nutrition.

Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects

H. Abaan, J. Troendle, A. Parle‐McDermott, 2014, BMC Medical Genetics.

The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation

Alexander F. Wilson, A. F. Wilson, H. McNulty, 2017, Human molecular genetics.

Folate fortification: enough already?

B. Shane, 2003, The American journal of clinical nutrition.

Folate and Vitamin B 12 Function

B. Shane, 2013 .

MTHFR C677T polymorphism increases MTX sensitivity via the inhibition of S-adenosylmethionine and de novo purine synthesis.

Der-Yuan Chen, B. Shane, E. Chiang, 2019, Clinical science.

Title Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects

P. Chines, J. Troendle, A. Parle‐McDermott, 2012 .

Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association.

A. Parle‐McDermott, L. Brody, J. Mills, 2005, Molecular genetics and metabolism.

First things first-addressing frank nutrient deficiencies must remain a priority in the age of precision nutrition.

P. Stover, B. Shane, 2023, The American journal of clinical nutrition.

Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.

P. Ueland, L. Brody, Aiyi Liu, 2014, The American journal of clinical nutrition.

Pteroylpoly(gamma-glutamate) synthesis by Corynebacterium species. Purification and properties of folypoly(gamma-glutamate) synthetase.

B. Shane, 1980, The Journal of biological chemistry.

Pteroylpoly(gamma-glutamate) synthesis by Corynebacterium species. Studies on the mechanism of folypoly(gamma-glutamate) synthetase.

B. Shane, 1980, The Journal of biological chemistry.

Dihydrofolate synthetase and folylpolyglutamate synthetase: direct evidence for intervention of acyl phosphate intermediates.

R. Banerjee, B. Shane, J. Coward, 1988, Biochemistry.

Bacterial folylpoly(gamma-glutamate) synthase-dihydrofolate synthase.

A. Bognar, B. Shane, 1986, Methods in enzymology.

Folylpoly-γ-Glutamate Synthetases: Properties and Regulation

B. Shane, D. J. Cichowicz, 1983 .

Biomarkers of Nutrition for Development-Folate Review.

M. Fenech, L. Bailey, H. McNulty, 2015, The Journal of nutrition.

A dihydrofolate reductase 2 (DHFR2) variant is associated with risk of neural tube defects in an Irish cohort but not in a United Kingdom cohort

A. Parle‐McDermott, L. Brody, J. Mills, 2021, American journal of medical genetics. Part A.

Identification of 10-formyltetrahydrofolate dehydrogenase-hydrolase as a major folate binding protein in liver cytosol.

E. Stokstad, B. Shane, B. Shane, 1988, Biochimica et biophysica acta.

A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.

H. Nijhout, C. Ulrich, M. Reed, 2006, The Journal of nutrition.

Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.

M. Brosnan, J. Brosnan, E. Gibney, 2015, The Journal of nutrition.

Theoretical Biology and Medical Modelling Open Access in Silico Experimentation with a Model of Hepatic Mitochondrial Folate Metabolism

C. Ulrich, M. Reed, B. Shane, 2022 .

Serine Hydroxymethyltransferase Anchors de Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis*

P. Stover, B. Shane, C. Woeller, 2012, The Journal of Biological Chemistry.