A. Irie

发表

Bladder cancer-associated cancer-testis antigen-derived long peptides encompassing both CTL and promiscuous HLA class II-restricted Th cell epitopes induced CD4+ T cells expressing converged T-cell receptor genes in vitro

S. Senju, Y. Nishimura, H. Hamana, 2018, Oncoimmunology.

Identification of SARS-COV Spike Protein-Derived and HLA-A2-Restricted Human CTL Epitopes by Using a New Muramyl Dipeptide-Derivative Adjuvant

M. Kohara, S. Senju, Y. Nishimura, 2010, International journal of immunopathology and pharmacology.

Augmentation of immune response by altered peptide ligands of the antigenic peptide in a human CD4+ T-cell clone reacting to TEL/AML1 fusion protein.

H. Fujita, S. Senju, S. Matsushita, 1999, Tissue antigens.

Peptides derived from human insulin‐like growth factor‐II mRNA binding protein 3 can induce human leukocyte antigen‐A2‐restricted cytotoxic T lymphocytes reactive to cancer cells

S. Senju, Y. Nishimura, K. Shiraishi, 2011, Cancer science.

Degenerate recognition and response of human CD4+ Th cell clones: implications for basic and applied immunology.

H. Yokomizo, S. Matsushita, Y. Nishimura, 2004, Molecular immunology.

Osteopontin expression of circulating T cells and plasma osteopontin levels are increased in relation to severity of heart failure.

Y. Nishimura, K. Kaikita, H. Ogawa, 2007, Circulation journal : official journal of the Japanese Circulation Society.

Elevated plasma osteopontin levels were associated with osteopontin expression of CD4+ T cells in patients with unstable angina.

Y. Nishimura, T. Sakamoto, H. Ogawa, 2005, Circulation journal : official journal of the Japanese Circulation Society.

Identification of the H2‐Kd‐restricted cytotoxic T lymphocyte epitopes of a tumor‐associated antigen, SPARC, which can stimulate antitumor immunity without causing autoimmune disease in mice

S. Senju, Y. Nishimura, H. Baba, 2009, Cancer science.

TCR ligand avidity determines the modeof B‐Raf/Raf‐1/ERK activation leading to the activationof human CD4+ T cell clone

Y. Nishimura, Kumiko Takeshita, Hirotake Tsukamoto, 2006, European journal of immunology.

Accumulation of HLA-DR4 in Colonic Epithelial Cells Causes Severe Colitis in Homozygous HLA-DR4 Transgenic Mice

Y. Nishimura, T. Imamura, N. Takeda, 2017, Inflammatory bowel diseases.

Accumulation of HLA-DR 4 in Colonic Epithelial Cells Causes Severe Colitis in Homozygous HLA-DR 4 Transgenic Mice

Y. Nishimura, T. Imamura, N. Takeda, 2022 .

Expression of interferon-g and interleukin-4 production in CD4+ T cells in patients with chronic heart failure

Y. Nishimura, T. Sakamoto, H. Ogawa, 2007, Heart and Vessels.

Identification of SPARC as a candidate target antigen for immunotherapy of various cancers

Yusuke Nakamura, Y. Furukawa, S. Senju, 2010, International journal of cancer.

An in vivo model of priming of antigen-specific human CTL by Mo-DC in NOD/Shi-scid IL2rgamma(null) (NOG) mice.

S. Senju, Y. Nishimura, H. Baba, 2009, Immunology letters.

Relation between CD4+ T-cell activation and severity of chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.

Y. Nishimura, K. Kaikita, H. Ogawa, 2007, The American journal of cardiology.

Selective inhibition of nuclear factor‐κB by nuclear factor‐κB essential modulator‐binding domain peptide suppresses the metastasis of highly metastatic oral squamous cell carcinoma

Y. Nishimura, S. Shinriki, A. Irie, 2012, Cancer science.

Identification of a Promiscuous Epitope Peptide Derived From HSP70

H. Nagano, Y. Nishimura, K. Tamada, 2019, Journal of immunotherapy.

A role of kinase inactive ZAP-70 in altered peptide ligand stimulated T cell activation.

Y. Nishimura, Hirotake Tsukamoto, A. Irie, 2006, Biochemical and biophysical research communications.

Preference Toward a T-Helper Type 1 Response in Patients With Coronary Spastic Angina

Y. Nishimura, I. Kajiwara, T. Sakamoto, 2003, Circulation.

A novel coculture system for assessing respiratory sensitizing potential by IL-4 in T cells.

S. Senju, Y. Nishimura, T. Yoshimoto, 2022, ALTEX.

B‐Raf‐mediated signaling pathway regulates T cell development

S. Senju, Y. Nishimura, L. Wojnowski, 2008, European journal of immunology.

A novel tumor‐associated antigen, cell division cycle 45‐like can induce cytotoxic T‐lymphocytes reactive to tumor cells

Yusuke Nakamura, S. Senju, Y. Nishimura, 2011, Cancer science.

Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4+ and CD8+ T-cell Epitopes: KIF20A-Specific CD4+ T-cell Immunity in Patients with Malignant Tumor

Yusuke Nakamura, S. Senju, Y. Nishimura, 2013, Clinical Cancer Research.

Expression of interferon-gamma and interleukin-4 production in CD4+ T cells in patients with chronic heart failure.

Y. Nishimura, T. Sakamoto, H. Ogawa, 2007, Heart and vessels.

Unique T cell proliferation associated with PKCμ activation and impaired ZAP‐70 phosphorylation in recognition of overexpressed HLA/partially agonistic peptide complexes

Y. Nishimura, Hirotake Tsukamoto, A. Irie, 2003, European Journal of Immunology.

Production of C5a by ASP, a Serine Protease Released from Aeromonas sobria1

H. Baba, K. Okamoto, T. Imamura, 2008, The Journal of Immunology.

Association of high cellular expression and plasma concentration of angiopoietin-like 4 with tongue cancer lung metastasis and poor prognosis

T. Imamura, A. Irie, H. Nakayama, 2022, Oncology letters.

Inhibition of Aeromonas sobria serine protease (ASP) by α2-macroglobulin

M. Hasegawa, K. Okamoto, T. Imamura, 2012, Biological chemistry.

Establishment of HLA-DR4 Transgenic Mice for the Identification of CD4+ T Cell Epitopes of Tumor-Associated Antigens

S. Senju, Y. Nishimura, H. Sugiyama, 2013, PloS one.

Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells.

Y. Nishimura, N. Araki, Hirotake Tsukamoto, 2006, International immunology.

Identification of CDCA1‐derived long peptides bearing both CD4+ and CD8+ T‐cell epitopes: CDCA1‐specific CD4+ T‐cell immunity in cancer patients

Yusuke Nakamura, S. Senju, Y. Nishimura, 2014, International journal of cancer.

Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus.

Y. Nishimura, J. Potempa, T. Imamura, 2011, Microbiology.

An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs

S. Senju, Y. Nishimura, K. Kono, 2016, Oncoimmunology.

Identification of glypican-3-derived long peptides activating both CD8+ and CD4+ T cells; prolonged overall survival in cancer patients with Th cell response

S. Senju, Y. Nishimura, K. Kono, 2015, Oncoimmunology.

Generation of dendritic cells and macrophages from human induced pluripotent stem cells aiming at cell therapy

S. Senju, Y. Nishimura, S. Fukushima, 2011, Gene Therapy.

The forkhead box M1 transcription factor as a candidate of target for anti‐cancer immunotherapy

Yusuke Nakamura, S. Senju, Y. Nishimura, 2009, International journal of cancer.

An Integrated Approach of Differential Mass Spectrometry and Gene Ontology Analysis Identified Novel Proteins Regulating Neuronal Differentiation and Survival*

N. Araki, A. Irie, Daiki Kobayashi, 2009, Molecular & Cellular Proteomics.

Neurofibromatosis Type 1 (NF1) Tumor Suppressor, Neurofibromin, Regulates the Neuronal Differentiation of PC12 Cells via Its Associating Protein, CRMP-2*

H. Saya, K. Kaibuchi, N. Araki, 2008, Journal of Biological Chemistry.

Activation of prothrombin by ASP, a serine protease released from Aeromonas sobria

H. Baba, K. Okamoto, T. Imamura, 2007, FEBS letters.

Differences between T-cell reactivities to major myelin protein-derived peptides in opticospinal and conventional forms of multiple sclerosis and healthy controls.

J. Kira, S. Matsushita, A. Irie, 2001, Tissue antigens.

High ratio of myeloid dendritic cells to plasmacytoid dendritic cells in blood of patients with acute coronary syndrome.

Y. Nishimura, K. Kaikita, H. Ogawa, 2009, Circulation journal : official journal of the Japanese Circulation Society.

Influence of the C5a–C5a receptor system on breast cancer progression and patient prognosis

Aiko Sueta, H. Iwase, T. Imamura, 2016, Breast Cancer.

B-Raf Contributes to Sustained Extracellular Signal-regulated Kinase Activation Associated with Interleukin-2 Production Stimulated through the T Cell Receptor*

Y. Nishimura, Hirotake Tsukamoto, A. Irie, 2004, Journal of Biological Chemistry.

Pro- and anti-apoptotic dual functions of the C5a receptor: involvement of regulator of G protein signaling 3 and extracellular signal-regulated kinase

H. Nishiura, Tetsurou Yamamoto, J. Kehrl, 2009, Laboratory Investigation.

Comparison of frequency of interferon-gamma-positive CD4+ T cells before and after percutaneous coronary intervention and the effect of statin therapy in patients with stable angina pectoris.

Y. Nishimura, K. Fujimoto, I. Kajiwara, 2004, The American journal of cardiology.

Enhancement of active MMP release and invasive activity of lymph node metastatic tongue cancer cells by elevated signaling via the TNF-α-TNFR1-NF-κB pathway and a possible involvement of angiopoietin-like 4 in lung metastasis.

T. Imamura, A. Irie, H. Nakayama, 2016, International journal of oncology.

Phosphorylation of SET Protein at Ser171 by Protein Kinase D2 Diminishes Its Inhibitory Effect on Protein Phosphatase 2A

Y. Nishimura, N. Araki, A. Irie, 2012, PloS one.

Identification of a Novel Tumor-Associated Antigen, Cadherin 3/P-Cadherin, as a Possible Target for Immunotherapy of Pancreatic, Gastric, and Colorectal Cancers

Yusuke Nakamura, Hidewaki Nakagawa, Hideo Baba, 2008, Clinical Cancer Research.

Identification of a NovelTumor-Associated Antigen , Cadherin 3 / P-Cadherin , as a PossibleTarget for Immunotherapy of Pancreatic , Gastric , and Colorectal Cancers

Yusuke Nakamura, H. Nakagawa, S. Senju, 2008 .

Identification of immunogenic LY6K long peptide encompassing both CD4+ and CD8+ T-cell epitopes and eliciting CD4+ T-cell immunity in patients with malignant disease

Yusuke Nakamura, S. Senju, Y. Nishimura, 2014, Oncoimmunology.

Development of an Ideal and Potent Cancer Immunotherapy Designed by Consideration of HLA Polymorphism

S. Senju, Y. Nishimura, Y. Tomita, 2013 .

HLA‐A2‐restricted CTL epitopes of a novel lung cancer‐associated cancer testis antigen, cell division cycle associated 1, can induce tumor‐reactive CTL

Yusuke Nakamura, S. Senju, Y. Nishimura, 2008, International journal of cancer.

Identification of HLA-A2-restricted CTL epitopes of a novel tumour-associated antigen, KIF20A, overexpressed in pancreatic cancer

Y. Nakamura, H. Nakagawa, S. Senju, 2010, British Journal of Cancer.

Involvement of CD44 in mast cell proliferation during terminal differentiation

K. Nakayama, Y. Sugimoto, A. Ichikawa, 2009, Laboratory Investigation.

Enhancement of Human Cancer Cell Motility and Invasiveness by Anaphylatoxin C5a via Aberrantly Expressed C5a Receptor (CD88)

H. Baba, G. Yamada, Y. Kawano, 2013, Clinical Cancer Research.

Flow cytometric analysis of mouse neurospheres based on the expression level of RANDAM-2

S. Okamoto, K. Itoh, H. Sakuraba, 2007, Neuroscience Letters.