H. Itoh

发表

Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding protein.

Y. Kaziro, T. Kishimoto, Taro Saito, 2003, Biochemical and biophysical research communications.

CEP164 Deficiency Causes Hyperproliferation of Pancreatic Cancer Cells

Tetsuo Kobayashi, Kosuke Tanaka, H. Itoh, 2020, Frontiers in Cell and Developmental Biology.

Betagamma subunits of pertussis toxin-sensitive G proteins mediate A1 adenosine receptor agonist-induced activation of phospholipase C in collaboration with thyrotropin. A novel stimulatory mechanism through the cross-talk of two types of receptors.

M. Ui, F. Okajima, H. Itoh, 1997, The Journal of biological chemistry.

G‐protein signalling negatively regulates the stability of aryl hydrocarbon receptor

Y. Fujii‐Kuriyama, Asuka Nakata, D. Urano, 2009, EMBO reports.

Distinct Pathways of Cell Migration and Antiapoptotic Response to Epithelial Injury: Structure-Function Analysis of Human Intestinal Trefoil Factor

D. Taupin, D. Podolsky, H. Itoh, 2000, Molecular and Cellular Biology.

Isolation and characterization of the human Gs alpha gene.

Y. Kaziro, T. Kozasa, H. Itoh, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and characterization of the human Gsa gene ( GTP-binding protein / alternative splicing / promoter / adenylate cyclase )

Y. Kaziro, T. Kozasa, H. Itoh, 2022 .

Involvement of Protein Kinase C and Src Family Tyrosine Kinase in Gαq/11-induced Activation of c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase*

Y. Kaziro, H. Itoh, J. Yamauchi, 1998, The Journal of Biological Chemistry.

Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling

Y. Kubo, T. Misaka, O. Saitoh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Signal transduction mediated through adhesion-GPCRs.

H. Itoh, N. Mizuno, 2010, Advances in experimental medicine and biology.

G protein-coupled receptor signaling through Gq and JNK negatively regulates neural progenitor cell migration.

H. Kokubu, H. Kurose, H. Itoh, 2005, Proceedings of the National Academy of Sciences of the United States of America.

LUCA15, a putative tumour suppressor gene encoding an RNA‐binding nuclear protein, is down‐regulated in ras‐transformed Rat‐1 cells

Y. Kaziro, H. Itoh, H. Edamatsu, 2000, Genes to cells : devoted to molecular & cellular mechanisms.

HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma

B. Dynlacht, Tetsuo Kobayashi, H. Itoh, 2017, EMBO reports.

HDAC 2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma

B. Dynlacht, Tetsuo Kobayashi, H. Itoh, 2017 .

Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Specific Cell Surface Binding Protein of Hepatocyte Growth Factor Activator (HGFA) and Regulates HGFA Activity in the Pericellular Microenvironment*

K. Miyazawa, N. Kitamura, T. Shimomura, 2000, The Journal of Biological Chemistry.

Cytosolic nuclease activated by caspase-3 and inhibited by DFF-45.

Y. Kaziro, H. Itoh, N. Mizuno, 1998, Biochemical and biophysical research communications.

RABL2 positively controls localization of GPCRs in mammalian primary cilia

Tetsuo Kobayashi, H. Itoh, Shuhei Chiba, 2019, Journal of Cell Science.

Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric‐8B in Gs suppression by Gq signal

H. Kurose, K. Tago, H. Itoh, 2013, Genes to cells : devoted to molecular & cellular mechanisms.

Gi-dependent Activation of c-Jun N-terminal Kinase in Human Embryonal Kidney 293 Cells*

Y. Kaziro, Takeharu Kawano, H. Itoh, 2000, The Journal of Biological Chemistry.

Requirement for Protein-tyrosine Phosphatase SHP-2 in Insulin-induced Activation of c-Jun NH2-terminal Kinase*

M. Kasuga, T. Matozaki, Y. Hayashi, 2000, The Journal of Biological Chemistry.

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

H. Kawasaki, K. Suzuki, T. Katada, 1986, Proceedings of the National Academy of Sciences of the United States of America.

G protein βγ subunit activates Ras, Raf, and MAP kinase in HEK 293 cells

Y. Kaziro, T. Satoh, H. Itoh, 1995 .

Presence of Three Distinct Molecular Species of Gi Protein a Subunit

R. Toyama, Y. Kaziro, T. Kozasa, 1988 .

G protein betagamma subunits induce stress fiber formation and focal adhesion assembly in a Rho-dependent manner in HeLa cells.

Y. Kaziro, K. Kato, H. Ueda, 2000, The Journal of biological chemistry.

Analysis by mRNA levels of the expression of six G protein alpha-subunit genes in mammalian cells and tissues.

Y. Kaziro, T. Kozasa, M. Matsuoka, 1991, Biochimica et biophysica acta.

The ram: A novel low molecular weight GTP‐binding protein cDNA from a rat megakaryocyte library

Y. Nozawa, Y. Kaziro, Y. Okano, 1990, FEBS letters.

Mechanism and Role of High Density Lipoprotein-induced Activation of AMP-activated Protein Kinase in Endothelial Cells*

I. Matsuoka, Masa-aki Ito, H. Kurose, 2009, The Journal of Biological Chemistry.

The Src family tyrosine kinase is involved in Rho-dependent activation of c-Jun N-terminal kinase by Gα12

Y. Kaziro, H. Itoh, M. Nagao, 1999, Oncogene.

Expression of an oncogenic mutant Gαi2 activates Ras in Rat‐1 fibroblast cells

Y. Kaziro, H. Itoh, H. Edamatsu, 1998 .

Ric-8B Stabilizes the α Subunit of Stimulatory G Protein by Inhibiting Its Ubiquitination*

Y. Nagai, K. Tago, H. Itoh, 2010, The Journal of Biological Chemistry.

Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit.

M. Matsuoka, Y. Kaziro, T. Kozasa, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Light-dependent activation of G proteins by two isoforms of chicken melanopsins

Y. Fukada, D. Kojima, H. Itoh, 2015, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Differential display of mRNAs regulated by G-protein signaling.

Y. Kaziro, H. Itoh, H. Edamatsu, 2002, Methods in enzymology.

Role of Dbl's big sister in the anti-mitogenic pathway from alpha1B-adrenergic receptor to c-Jun N-terminal kinase.

G. Tsujimoto, A. Hirasawa, H. Kokubu, 2002, Biochemical and biophysical research communications.

Activation of Stat1 and subsequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is independent of interferon‐γ‐induced MAPK activation that is mediated by p21 ras

T. Uehara, Y. Kaziro, H. Itoh, 1997, FEBS letters.

Involvement of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase in alpha1B-adrenergic receptor/Galphaq-induced inhibition of cell proliferation.

G. Tsujimoto, Y. Kaziro, H. Shinoura, 2001, Biochemical and biophysical research communications.

CHAPTER 4 – Organization of Genes Coding for G-Protein α Subunits in Higher and Lower Eukaryotes

M. Nakafuku, Y. Kaziro, H. Itoh, 1990 .

Regulation of the Golgi structure by the α subunits of heterotrimeric G proteins

M. Tagaya, K. Tani, H. Itoh, 2000 .

KIF24 controls the clustering of supernumerary centrosomes in pancreatic ductal adenocarcinoma cells

B. Dynlacht, H. Itoh, Yu Mashima, 2022, bioRxiv.

Thrombin‐induced inhibition of myoblast differentiation is mediated by Gβγ

Y. Kaziro, H. Itoh, M. Nagao, 2000, FEBS letters.

Gα11 Induces Caspase-mediated Proteolytic Activation of Rho-associated Kinase, ROCK-I, in HeLa Cells*

K. Mikoshiba, S. Narumiya, T. Asano, 2001, The Journal of Biological Chemistry.

Licochalcone A Potently Inhibits Tumor Necrosis Factor α-Induced Nuclear Factor-κB Activation through the Direct Inhibition of IκB Kinase Complex Activation

T. Mashino, T. Kasahara, M. Funakoshi-Tago, 2009, Molecular Pharmacology.

Differential regulation of mitogen-activated protein kinase kinase 4 (MKK4) and 7 (MKK7) by signaling from G protein beta gamma subunit in human embryonal kidney 293 cells.

Y. Kaziro, H. Itoh, J. Yamauchi, 1999, The Journal of biological chemistry.

Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cells.

Y. Kobayashi, K. Tago, H. Itoh, 2015, Biological & pharmaceutical bulletin.

KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells

B. Dynlacht, H. Itoh, Yu Mashima, 2022, Life Science Alliance.

Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions.

K. Arai, K. Matsumoto, M. Nakafuku, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Structures of the genes coding for G-protein alpha subunits from mammalian and yeast cells.

M. Nakafuku, R. Toyama, Y. Kaziro, 1988, Cold Spring Harbor symposia on quantitative biology.

Identification of sites for alkylation by N‐ethylmaleimide and pertussis toxin‐catalyzed ADP‐ribosylation on GTP‐binding proteins

H. Kawasaki, K. Suzuki, S. Hoshino, 1990, FEBS letters.

Purification, identification, and characterization of two GTP-binding proteins with molecular weights of 25,000 and 21,000 in human platelet cytosol. One is the rap1/smg21/Krev-1 protein and the other is a novel GTP-binding protein.

T. Katada, Y. Nozawa, Y. Kaziro, 1989, The Journal of biological chemistry.

Activation of c-fos Promoter by Gβγ-Mediated Signaling: Involvement of Rho and c-Jun N-Terminal Kinase

Yunjie Sun, Y. Kaziro, H. Itoh, 1999 .

Activation of c-fos promoter by Gbetagamma-mediated signaling: involvement of Rho and c-Jun N-terminal kinase.

Y. Kaziro, Y. Sun, H. Itoh, 1999, Journal of biochemistry.

Activation of the G protein Gq/11 through tyrosine phosphorylation of the α subunit

K. Mikoshiba, S. Nakanishi, Takafumi Inoue, 1997 .

Phosphorylation of Doublecortin by Protein Kinase A Orchestrates Microtubule and Actin Dynamics to Promote Neuronal Progenitor Cell Migration*

K. Tago, H. Itoh, Michinori Toriyama, 2012, The Journal of Biological Chemistry.

Actin Dynamics to Promote Neuronal Kinase A Orchestrates Microtubule and Phosphorylation of Doublecortin by Protein Signal Transduction :

Fukami, K. Tago, H. Itoh, 2012 .

Structure and function of signal-transducing GTP-binding proteins.

M. Nakafuku, Y. Kaziro, T. Kozasa, 1991, Annual review of biochemistry.

Heterotrimeric G-Proteins: α, β, and γ Subunits

Y. Kaziro, H. Itoh, 1993 .

Arf tumor suppressor disrupts the oncogenic positive feedback loop including c-Myc and DDX5

Y. Furukawa, J. Kikuchi, K. Suzuki, 2014, Oncogene.

Regulation of Rac and Cdc42 Pathways by Gi during Lysophosphatidic Acid-induced Cell Spreading*

T. Asano, Kanefusa Kato, H. Itoh, 2001, The Journal of Biological Chemistry.

Ras Oncoprotein Induces CD44 Cleavage through Phosphoinositide 3-OH Kinase and the Rho Family of Small G Proteins*

H. Saya, Y. Kawano, S. Ueda, 2000, The Journal of Biological Chemistry.

α Helix Content of G Protein α Subunit Is Decreased upon Activation by Receptor Mimetics*

Takeshi Tanaka, T. Kohno, T Tanaka, 1998, The Journal of Biological Chemistry.

Activation of p38 Mitogen-activated Protein Kinase by Signaling through G Protein-coupled Receptors

Y. Kaziro, H. Itoh, J. Yamauchi, 1997, The Journal of Biological Chemistry.

Celecoxib potently inhibits TNFalpha-induced nuclear translocation and activation of NF-kappaB.

T. Kasahara, M. Funakoshi-Tago, K. Tago, 2008, Biochemical pharmacology.

NESK, a Member of the Germinal Center Kinase Family That Activates the c-Jun N-terminal Kinase Pathway and Is Expressed during the Late Stages of Embryogenesis*

N. Kitamura, H. Itoh, J. Yamauchi, 2000, The Journal of Biological Chemistry.

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

R. Jessberger, Y. Gotoh, N. Mochizuki, 2002, Nature.

Bikunin Target Genes in Ovarian Cancer Cells Identified by Microarray Analysis*

Y. Saga, Mitsuaki Suzuki, Y. Hirashima, 2003, The Journal of Biological Chemistry.

Inducible high-level expression vector for mammalian cells, pEF-LAC carrying human elongation factor 1alpha promoter and lac operator.

Y. Kaziro, H. Itoh, H. Edamatsu, 1997, Gene.

Critical Duration of Intracellular Ca2+ Response Required for Continuous Translocation and Activation of Cytosolic Phospholipase A2 *

Takao Shimizu, Takehiko Yokomizo, Kenzo Hirose, 1999, The Journal of Biological Chemistry.

Src Kinase Regulates the Activation of a Novel FGD-1-related Cdc42 Guanine Nucleotide Exchange Factor in the Signaling Pathway from the Endothelin A Receptor to JNK*

H. Itoh, Y. Miyamoto, J. Yamauchi, 2003, Journal of Biological Chemistry.

The Adaptor Protein Nck1 Mediates Endothelin A Receptor-regulated Cell Migration through the Cdc42-dependent c-Jun N-terminal Kinase Pathway*

H. Itoh, Y. Miyamoto, J. Yamauchi, 2004, Journal of Biological Chemistry.

Expression and analysis of Gs alpha mutants with decreased ability to activate adenylylcyclase.

A. Gilman, H. Itoh, 1991, The Journal of biological chemistry.

p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5

R. Brachmann, M. Asaka, L. Sutherland, 2011, International journal of cancer.

CD47 Promotes Neuronal Development through Src- and FRG/Vav2-Mediated Activation of Rac and Cdc42

T. Matozaki, H. Itoh, H. Okazawa, 2006, The Journal of Neuroscience.

Functions and Regulatory Mechanisms of Gq-Signaling Pathways

H. Itoh, N. Mizuno, 2009, Neurosignals.

Orphan G Protein-coupled Receptor GPR56 Regulates Neural Progenitor Cell Migration via a Gα12/13 and Rho Pathway*

K. Tago, H. Itoh, N. Mizuno, 2008, Journal of Biological Chemistry.

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

R. Toyama, Y. Kaziro, T. Kozasa, 1988, The Journal of biological chemistry.

Involvement of c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase in α1B-Adrenergic Receptor/Gαq-Induced Inhibition of Cell Proliferation

G. Tsujimoto, Y. Kaziro, H. Shinoura, 2001 .

Phosphorylation of F-actin-Associating G Protein γ12 Subunit Enhances Fibroblast Motility*

Y. Kaziro, T. Asano, Kanefusa Kato, 1999, The Journal of Biological Chemistry.

Importance of the G protein γ subunit in activating G protein‐coupled inward rectifier K+ channels

Y. Kaziro, Takeharu Kawano, H. Itoh, 1999, FEBS letters.

Calcium phosphate-mediated transfection of primary cultured brain neurons using GFP expression as a marker: application for single neuron electrophysiology

Y. Kaziro, Takeharu Kawano, H. Itoh, 1999, Neuroscience Research.

Ric‐8A potentiates Gq‐mediated signal transduction by acting downstream of G protein‐coupled receptor in intact cells

H. Itoh, J. Yamauchi, N. Mizuno, 2006, Genes to cells : devoted to molecular & cellular mechanisms.

Structure of the human gene and two rat cDNAs encoding the alpha chain of GTP-binding regulatory protein Go: two different mRNAs are generated by alternative splicing.

R. Toyama, Y. Kaziro, T. Kozasa, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Identification of lung major GTP-binding protein as Gi2 and its distribution in various rat tissues determined by immunoassay.

Y. Kaziro, K. Kato, T. Asano, 1989, Biochemistry.

GTP‐binding proteins in human platelet membranes serving as the specific substrate of islet‐activating protein, pertussis toxin

T. Katada, Y. Kaziro, M. Tohkin, 1988, FEBS letters.

Identification of three pertussis toxin substrates (41, 40 and 39 kDa proteins) in mammalian brain Comparison of predicted amino acid sequences from G‐protein α‐subunit genes and cDNAs with partial amino acid sequences from purified proteins

H. Kawasaki, T. Katada, Y. Kaziro, 1988, FEBS letters.

Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit.

K. Mikoshiba, S. Nakanishi, T. Inoue, 1997, Science.

Identification of Cis-elements of the Human Endothelin-A Receptor Gene and Inhibition of the Gene Expression by the Decoy Strategy*

K. Nakao, H. Itoh, H. Arai, 1998, The Journal of Biological Chemistry.

Dynamic Mobility of Immunological Cells Expressing S100A8 and S100A9 in vivo: A Variety of Functional Roles of the two Proteins as Regulators in Acute Inflammatory Reaction

S. Arai, H. Itoh, S. Uemoto, 2011, Inflammation.

C-terminal Mutation of G Protein β Subunit Affects Differentially Extracellular Signal-regulated Kinase and c-Jun N-terminal Kinase Pathways in Human Embryonal Kidney 293 Cells*

Y. Kaziro, H. Itoh, J. Yamauchi, 1997, The Journal of Biological Chemistry.

κB-Ras Is a Nuclear-Cytoplasmic Small GTPase That Inhibits NF-κB Activation through the Suppression of Transcriptional Activation of p65/RelA*

M. Funakoshi-Tago, K. Tago, H. Itoh, 2010, The Journal of Biological Chemistry.

Parallel Regulation of Mitogen-activated Protein Kinase Kinase 3 (MKK3) and MKK6 in Gq-signaling Cascade*

G. Tsujimoto, Y. Kaziro, H. Itoh, 2001, The Journal of Biological Chemistry.

GPR56 C‐terminal fragment mediates signal received by N‐terminal fragment of another adhesion GPCR Latrophilin1 in neurons

K. Tago, K. Morishita, H. Itoh, 2022, Genes to cells : devoted to molecular & cellular mechanisms.

Beta2-adrenergic receptor/cyclic adenosine monophosphate (cAMP) leads to JNK activation through Rho family small GTPases.

G. Tsujimoto, A. Hirasawa, H. Itoh, 2001, Biochemical and biophysical research communications.

Conversion of adrenergic mechanism from an alpha- to a beta-type during primary culture of rat hepatocytes. Accompanying decreases in the function of the inhibitory guanine nucleotide regulatory component of adenylate cyclase identified as the substrate of islet-activating protein.

M. Ui, F. Okajima, H. Itoh, 1984, The Journal of biological chemistry.

Endothelin suppresses cell migration via the JNK signaling pathway in a manner dependent upon Src kinase, Rac1, and Cdc42

G. Tsujimoto, A. Hirasawa, H. Kokubu, 2002, FEBS letters.

Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the alpha subunit of mammalian G proteins.

M. Nakafuku, Y. Kaziro, S. Nakamura, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule

T. Hakoshima, M. Taniguchi, K. Tago, 2010, Proceedings of the National Academy of Sciences.

Hamster alpha 1B-adrenergic receptor directly activates Gs in the transfected Chinese hamster ovary cells.

G. Tsujimoto, H. Itoh, K. Horie, 1995, Molecular pharmacology.

Cholesterol in the ciliary membrane as a therapeutic target against cancer

H. Itoh, T. Miyamoto, Sotai Kimura, 2023, Frontiers in Molecular Biosciences.

A glutamate residue at the C terminus regulates activity of inward rectifier K+ channels: Implication for Andersen's syndrome

Y. Kaziro, Takeharu Kawano, H. Itoh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Loss of a primary cilium in PDAC

Tetsuo Kobayashi, H. Itoh, 2017, Cell cycle.

CEP164-GLI2 association ensures the hedgehog signaling in pancreatic cancer cells.

H. Itoh, Tetsuo Kobayashi, Toshihiko Fushimi, 2023, Biochemical and biophysical research communications.

Atypical small GTPase RABL3 interacts with RAB11 to regulate early ciliogenesis in human cells

H. Itoh, Tatsuya Ikeda, Reo Ota, 2022, bioRxiv.

Purification and identification of two pertussis-toxin-sensitive GTP-binding proteins of bovine spleen.

Y. Kaziro, K. Kato, T. Asano, 1989, Biochemical and Biophysical Research Communications - BBRC.

The lipid raft proteins flotillins/reggies interact with Galphaq and are involved in Gq-mediated p38 mitogen-activated protein kinase activation through tyrosine kinase.

Tomoko Takahashi, K. Tago, H. Itoh, 2007, Cellular signalling.

The mechanism of membrane‐translocation of regulator of G‐protein signaling (RGS) 8 induced by Gα expression

O. Saitoh, I. Masuho, H. Itoh, 2003, Journal of neurochemistry.

Involvement of protein kinase C and Src family tyrosine kinase in Galphaq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase.

Y. Kaziro, H. Itoh, J. Yamauchi, 1998, The Journal of biological chemistry.

Domain-domain interaction of P-Rex1 is essential for the activation and inhibition by G protein betagamma subunits and PKA.

Asuka Nakata, D. Urano, K. Tago, 2008, Cellular signalling.

Expression of an oncogenic mutant G alpha i2 activates Ras in Rat-1 fibroblast cells.

Y. Kaziro, H. Itoh, H. Edamatsu, 1998, FEBS letters.

Characterization of the human gene for Gx alpha, a pertussis toxin-insensitive regulatory GTP-binding protein.

M. Matsuoka, Y. Kaziro, M. Matsuoka, 1990, The Journal of biological chemistry.

G protein beta gamma subunit activates Ras, Raf, and MAP kinase in HEK 293 cells.

Y. Kaziro, T. Satoh, H. Itoh, 1995, FEBS Letters.

Differential Regulation of Mitogen-activated Protein Kinase Kinase 4 (MKK4) and 7 (MKK7) by Signaling from G Protein βγ Subunit in Human Embryonal Kidney 293 Cells*

Y. Kaziro, H. Itoh, J. Yamauchi, 1999, The Journal of Biological Chemistry.

Preferential expression of the third immunoglobulin-like domain of K-sam product provides keratinocyte growth factor-dependent growth in carcinoma cell lines.

H. Ishii, Teruhiko Yoshida, T. Sugimura, 1994, Cancer research.

Maintenance of the hematopoietic stem cell pool in bone marrow niches by EVI1-regulated GPR56

Y. Saito, H. Itoh, I. Miura, 2013, Leukemia.

Galphaq-dependent activation of mitogen-activated protein kinase kinase 4/c-Jun N-terminal kinase cascade.

G. Tsujimoto, Y. Kaziro, H. Shinoura, 2001, Biochemical and biophysical research communications.

G Protein βγ Subunits Induce Stress Fiber Formation and Focal Adhesion Assembly in a Rho-dependent Manner in HeLa Cells*

Y. Kaziro, H. Ueda, T. Asano, 2000, The Journal of Biological Chemistry.

Cis Elements for Transcriptional Regulation of the Human Endothelin‐A Receptor Gene

K. Nakao, H. Arai, K. Takaya, 1995, Journal of cardiovascular pharmacology.

p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5

R. Brachmann, M. Asaka, L. Sutherland, 2011, International journal of cancer.

Mechanism and Role of High Density Lipoprotein-induced Activation of AMP-activated Protein Kinase in Endothelial Cells*

I. Matsuoka, Masa-aki Ito, H. Kurose, 2009, The Journal of Biological Chemistry.

Phosphorylation of Doublecortin by Protein Kinase A Orchestrates Microtubule and Actin Dynamics to Promote Neuronal Progenitor Cell Migration*

K. Tago, H. Itoh, Michinori Toriyama, 2012, The Journal of Biological Chemistry.

cDNA sequencing of mouse alpha 1-microglobulin/inter-alpha-trypsin inhibitor light chain and its expression in acute inflammation.

H. Kataoka, H. Itoh, H. Itoh, 1994, Journal of biochemistry.

HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma

B. Dynlacht, Tetsuo Kobayashi, H. Itoh, 2017, EMBO reports.

Domain-domain interaction of P-Rex1 is essential for the activation and inhibition by G protein betagamma subunits and PKA.

Asuka Nakata, D. Urano, K. Tago, 2008, Cellular signalling.

Carboxyl Terminal of G Protein β Subunit Is Required for Association with γ Subunit

Y. Kaziro, H. Itoh, J. Yamauchi, 1995 .

Licochalcone A Potently Inhibits Tumor Necrosis Factor α-Induced Nuclear Factor-κB Activation through the Direct Inhibition of IκB Kinase Complex Activation

T. Mashino, T. Kasahara, M. Funakoshi-Tago, 2009, Molecular Pharmacology.

Mast cell protease inhibitor, trypstatin, is a fragment of inter-alpha-trypsin inhibitor light chain.

H. Itoh, H. Itoh, Y. Nawa, 1994, The Journal of biological chemistry.

Multiple Transcripts of Human Endothelin‐A Receptor Gene Detected by Reverse Transcription and the Polymerase Chain Reaction

K. Nakao, H. Arai, K. Takaya, 1995, Journal of cardiovascular pharmacology.