Saeed R. Khan

发表

Synthesis and cytotoxicity studies of Hedgehog enzyme inhibitors SANT-1 and GANT-61 as anticancer agents

Venugopal Chenna, Chaoxin Hu, Saeed R. Khan, 2014, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

Rational design of novel antiandrogens for neutralizing androgen receptor function in hormone refractory prostate cancer

J. Isaacs, O. Bakare, Y. Kageyama, 2008, The Prostate.

Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents.

N. Davidson, Saeed R. Khan, Srinivas K. Kumar, 2003, Journal of Medicinal Chemistry.

Anticancer activities of novel chalcone and bis-chalcone derivatives.

N. Davidson, G. Achanta, Saeed R. Khan, 2006, Bioorganic & medicinal chemistry.

Biological evaluation of Paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery

N. Neamati, Saeed R. Khan, R. Anchoori, 2010, Cancer biology & therapy.

Chemistry of the phenoxathiins and isosterically related heterocycles. XXXVII The synthesis and molecular structure of benzo[2, 3]naphtho[5, 6, 7-ij][1, 4]dithiepin and its 1-oxide†

V. Lynch, A. Zektzer, G. Martin, 1989 .

Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer.

H. Lilja, E. Garrett, J. Isaacs, 2003, Journal of the National Cancer Institute.

A Boronic-Chalcone Derivative Exhibits Potent Anticancer Activity through Inhibition of the Proteasome

G. Achanta, Li Feng, Saeed R. Khan, 2006, Molecular Pharmacology.

Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer.

A. Maitra, P. Beachy, I. Roy, 2008, Bioorganic & medicinal chemistry.

In vitro and In vivo Clinical Pharmacology of Dimethyl Benzoylphenylurea, a Novel Oral Tubulin-Interactive Agent

Manuel Hidalgo, Ming Zhao, Robert W. Robey, 2005, Clinical Cancer Research.

Synthesis and antitumor evaluation of benzoylphenylurea analogs.

M. Hidalgo, M. Rudek, Ming Zhao, 2004, Bioorganic & medicinal chemistry letters.

α,β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus (HPV) positive cervical cancer cells.

R. Roden, R. Gavioli, B. Karanam, 2011, Journal of medicinal chemistry.

A 5-fluorodeoxyuridine prodrug as targeted therapy for prostate cancer.

J. Isaacs, S. Denmeade, Wei Yao, 2002, Bioorganic & medicinal chemistry letters.

Modulating paclitaxel bioavailability for targeting prostate cancer.

Simon A. Williams, J. Isaacs, S. Denmeade, 2007, Bioorganic & medicinal chemistry.

In Vivo activity of a PSA‐activated doxorubicin prodrug against PSA‐producing human prostate cancer xenografts

S. Denmeade, Saeed R. Khan, 2000, The Prostate.

Inhibition of IkB kinase and NF-kappaB by a novel synthetic compound SK 2009.

B. Aggarwal, K. Harikumar, Saeed R. Khan, 2010, Bioorganic & medicinal chemistry.

Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy.

M. Hidalgo, P. Diest, E. Hamel, 2008, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel riccardiphenol analogs.

M. Hidalgo, Saeed R. Khan, S. Bhat, 2005, Bioorganic & Medicinal Chemistry.

Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents.

N. Davidson, Saeed R. Khan, Srinivas K. Kumar, 2003, Journal of medicinal chemistry.

Design, synthesis and evaluation of new RDP inhibitors

K. Kinzler, B. Vogelstein, P. Buckhaults, 2003 .

Benzoylphenylurea sulfur analogues with potent antitumor activity.

S. Sukumar, A. Jimeno, M. Hidalgo, 2006, Journal of medicinal chemistry.

Stressing the Ubiquitin-Proteasome System without 20S Proteolytic Inhibition Selectively Kills Cervical Cancer Cells

R. Roden, R. Gavioli, Federica Destro, 2011, PloS one.

Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase.

K. Kinzler, B. Vogelstein, Saeed R. Khan, 2004, Bioorganic & medicinal chemistry letters.

Sesquiterpenes: natural products that decrease cancer growth.

Saeed R. Khan, A. Modzelewska, Surojit Sur, 2005, Current medicinal chemistry. Anti-cancer agents.

Bis(carbamoyloxymethyl) Esters of 2′,3′-Dideoxyuridine 5′-monophosphate (ddUMP) as Potential ddUMP Prodrugs

D. Farquhar, Saeed R. Khan, Srinivas K. Kumar, 2005, Pharmaceutical Research.

Benzohydrazides, benzothiohydrazides, and benzamidrazones as sources of 1,3,4(2H)‐oxadiazolenones, 1,3,4(2H)‐thiadiazolenones, and 1,2,4(5H)‐triazolenones

Saeed R. Khan, M. Gibson, S. Fung, 1986 .

A Polymeric Nanoparticle Encapsulated Small-Molecule Inhibitor of Hedgehog Signaling (NanoHHI) Bypasses Secondary Mutational Resistance to Smoothened Antagonists

C. Rudin, A. Maitra, Seung‐Mo Hong, 2011, Molecular Cancer Therapeutics.

Fenugreek: A naturally occurring edible spice as an anticancer agent

A. Jimeno, M. Hidalgo, M. Carducci, 2009, Cancer biology & therapy.

Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer

A. Jimeno, M. Hidalgo, E. Garrett-Mayer, 2007, Molecular Cancer Therapeutics.

Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer

V. Stearns, C. Umbricht, M. Allu, 2011, Cancer biology & therapy.

Reactions of steroidal 5,6-epoxides and cyclohexene oxide with aluminum alkoxides

Saeed R. Khan, H. Holland, 1985 .

Concentration of enzymatically active prostate‐specific antigen (PSA) in the extracellular fluid of primary human prostate cancers and human prostate cancer xenograft models

D. Chan, L. Sokoll, J. Isaacs, 2001, The Prostate.

Activation of latent protease function of pro‐hk2, but not pro‐PSA, involves autoprocessing

H. Lilja, J. Isaacs, S. Denmeade, 2001, The Prostate.

Activationof Latent Protease Functionof Pro-HK2,

J. Isaacs, Saeed R. Khan, R. Denmeade, 2022 .

Bis(pivaloyloxymethyl) thymidine 5'-phosphate is a cell membrane-permeable precursor of thymidine 5'-phosphate in thymidine kinase deficient CCRF CEM cells.

W. Plunkett, D. Farquhar, Saeed R. Khan, 2005, Biochemical pharmacology.