I. Hofmann

发表

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis.

Michael G. Kharas, S. Armstrong, A. McMahon, 2009, Cell stem cell.

A novel macromolecular prodrug concept exploiting endogenous serum albumin as a drug carrier for cancer chemotherapy.

J. Drevs, C. Unger, F. Kratz, 2000, Journal of medicinal chemistry.

Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction

David A. Williams, S. Gabriel, N. Gupta, 2020, Journal of Clinical Immunology.

Distinct genetic pathways define pre-leukemic and compensatory clonal hematopoiesis in Shwachman-Diamond syndrome

Nicholas D. Camarda, S. Carter, M. Norkin, 2020, bioRxiv.

Myelodysplastic syndromes and myeloproliferative disorders

N. Hijiya, I. Hofmann, M. Elghetany, 2022, Lanzkowsky's Manual of Pediatric Hematology and Oncology.

Chapter 17 – Myelodysplastic Syndromes and Myeloproliferative Disorders

I. Hofmann, T. Elghetany, 2016 .

Induction of Histiocytic Sarcoma in Mouse Skeletal Muscle

Christine M. Miller, R. Bronson, A. Wagers, 2012, PloS one.

When should transplant physicians think about familial blood cancers?

H. Carraway, Q. Bashir, L. Godley, 2019, Journal of Clinical Haematology.

Comparison of outcomes of myeloablative allogeneic stem cell transplantation for pediatric patients with bone marrow failure, myelodysplastic syndrome and acute myeloid leukemia with and without germline GATA2 mutations.

W. London, L. Lehmann, I. Hofmann, 2020, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer

Kirby D. Johnson, S. Keleş, E. Bresnick, 2019, The Journal of clinical investigation.

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice.

W. Ouwehand, A. Barr, R. Favier, 2018, Blood.

CTC1 Mutations in a patient with dyskeratosis congenita

Rachel B. Keller, Suneet Agarwal, I. Hofmann, 2012, Pediatric blood & cancer.

Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9.

Szymon J. Ciesielski, Meghan C Towne, P. Newburger, 2015, Blood.

Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity

David A. Williams, T. Walsh, M. King, 2015, Haematologica.

In Vivo and In Vitro Efficacy of an Acid-Sensitive Albumin Conjugate of Adriamycin Compared to the Parent Compound in Murine Renal-Cell Carcinoma

J. Drevs, D. Marmé, C. Unger, 1999 .

Acute lymphoblastic leukemia in a patient with MonoMAC syndrome/GATA2 haploinsufficiency

A. Koegel, K. Moffitt, I. Hofmann, 2016, Pediatric blood & cancer.

TGFb signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome

C. Nusbaum, T. Libermann, Guocheng Yuan, 2019 .

TGF b signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome

C. Nusbaum, T. Libermann, Guocheng Yuan, 2019 .

Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome

Nicholas D. Camarda, S. Carter, M. Norkin, 2021, Nature Communications.

TGFβ signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome.

C. Nusbaum, T. Libermann, Guocheng Yuan, 2019, The Journal of clinical investigation.

Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy

David A. Williams, T. Walsh, M. King, 2015, Nature Genetics.

Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model.

G. Martiny-Baron, J. Wood, J. Drevs, 2000, Cancer research.

Congenital X‐linked neutropenia with myelodysplasia and somatic tetraploidy due to a germline mutation in SEPT6

David A. Williams, B. Ebert, T. Springer, 2021, American journal of hematology.

Effects of PTK 787 / ZK 222584 , a Specific Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases , on Primary Tumor , Metastasis , Vessel Density , and Blood Flow in a Murine Renal Cell Carcinoma Model 1

G. Martiny-Baron, J. Wood, J. Drevs, 2000 .

Downregulating Notch counteracts KrasG12D-induced ERK activation and oxidative phosphorylation in myeloproliferative neoplasm

M. Loh, W. Pear, E. Ranheim, 2018, Leukemia.

Pediatric aplastic anemia and refractory cytopenia: A retrospective analysis assessing outcomes and histomorphologic predictors

David A. Williams, M. Harris, W. London, 2015, American journal of hematology.

Poly(A)-specific ribonuclease (PARN) mediates 3′-end maturation of the telomerase RNA component

P. Cahan, E. Guinan, Suneet Agarwal, 2015, Nature Genetics.

Pediatric myelodysplastic syndromes

I. Hofmann, 2015, Journal of Hematopathology.

Diagnosis and treatment of pediatric myelodysplastic syndromes: A survey of the North American Pediatric Aplastic Anemia Consortium

T. Olson, M. Wlodarski, A. Shimamura, 2020, Pediatric blood & cancer.

Myeloproliferative neoplasms in children

I. Hofmann, 2015, Journal of Hematopathology.

Mutations of the hemophagocytic lymphohistiocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis.

A. Filipovich, M. Hazen, I. Hofmann, 2008, Arthritis and rheumatism.

Hematopoietic Stem Cell Transplant for Shwachman Diamond Syndrome.

M. MacMillan, K. Myers, M. Eapen, 2020, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

GATA2 Mutations In Pediatric Myelodysplastic Syndromes and Bone Marrow Failure

David A. Williams, M. Loh, M. Fleming, 2013 .

Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity

David A. Williams, T. Walsh, M. King, 2015, Haematologica.