J. Stobaugh

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Suitability of DTAF as a fluorescent labelling reagent for direct analysis of primary and secondary amines--spectral and chemical reactivity considerations.

R. Siegler, L. Sternson, J. Stobaugh, 1989, Journal of pharmaceutical and biomedical analysis.

Profiling the Photochemical-Induced Degradation of Rat Growth Hormone with Extreme Ultra-pressure Chromatography–Mass Spectrometry Utilizing Meter-Long Microcapillary Columns Packed with Sub-2-µm Particles

J. Jorgenson, M. Forrest, C. Schöneich, 2017, Chromatographia.

Using Lysine-Reactive Fluorescent Dye for Surface Characterization of a Monoclonal Antibody

Y. Kao, C. Quan, J. Stults, 2014 .

Amino acid and peptide analysis using derivatization with p-nitrophenol-2,5-dihydroxyphenylacetate bis-tetrahydropyranyl ether and capillary electrophoresis with electrochemical detection.

S. Lunte, M. Rose, J. Stobaugh, 2003, Journal of pharmaceutical and biomedical analysis.

Determination of alpha-difluoromethylornithine in blood by microdialysis sampling and capillary electrophoresis with UV detection.

S. Lunte, C. Riley, J. Stobaugh, 1995, Journal of chromatography. A.

The Development of a Sheathless Interface for Capillary Electrophoresis Electrospray Ionization Mass Spectrometry Using a Cellulose Acetate Cast Capillary

C. Lunte, J. Stobaugh, Ryan T. Johnson, 2017, Chromatographia.

Chemiluminescence: a sensitive and versatile method for analyte detection.

R. Givens, H. Chokshi, C. Riley, 1990, Journal of pharmaceutical and biomedical analysis.

Applications of Capillary Electrophoresis in Pharmaceutical Analysis

J. Stobaugh, S. Rabel, 1993, Pharmaceutical Research.

Determination of angiotensin II in blood–brain barrier permeability studies using microbore LC with p-nitrophenyl-2,5-dihydroxyphenylacetate bis-tetrahydropyranyl ether as a pre-separation electrochemical labeling reagent

K. Audus, S. Lunte, M. Rose, 1999 .

Fluorogenic derivatization of peptides with naphthalene-2,3-dicarboxaldehyde/cyanide: optimization of yield and application in the determination of leucine-enkephalin spiked human plasma samples.

C. Riley, L. Sternson, J. Stobaugh, 1990, Journal of pharmaceutical and biomedical analysis.

Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS.

T. Williams, M. Becker, J. Stobaugh, 2011, Bioanalysis.

Fluorogenic Tagging of Peptide and Protein 3-Nitrotyrosine with 4-(Aminomethyl)benzenesulfonic Acid for Quantitative Analysis of Protein Tyrosine Nitration

R. Dobrowsky, C. Schöneich, J. Stobaugh, 2010, Chromatographia.

Role of capillary electrophoresis methods in the drug development process

D. Skanchy, J. Stobaugh, E. Rickard, 1996 .

Selective fluorogenic derivatization of 3-nitrotyrosine and 3,4-dihydroxyphenylalanine in peptides: a method designed for quantitative proteomic analysis.

Jacqueline D. Killmer, C. Schöneich, J. Stobaugh, 2008, Methods in enzymology.

Phenylisothiocyanate as a Multiple Chemical Dimension Reagent for the Relative Quantitation of Protein Nitrotyrosine

Jacqueline D. Killmer, C. Schöneich, J. Stobaugh, 2008 .

Target specific sample preparation from aqueous extracts with molecular imprinted polymers.

J. Stobaugh, S. Moring, O. Wong, 2002, Journal of pharmaceutical and biomedical analysis.

Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier.

K. Audus, J. Stobaugh, G. Chandorkar, 2002, International journal of pharmaceutics.

Mechanism Based Design of Amine Fluorogenic Derivatization Reagents: Proof of Concept, Physical–Chemical Characterization and Initial Analytical Derivatization Protocols

J. Stobaugh, L. L. McChesney-Harris, S. V. Kakodakar, 2013, Chromatographia.

CHAPTER 2 - Novel Approaches to the Liquid Chromatographic Analysis of Primary Amines, Amino Acids and Peptides

S. Lunte, C. Riley, J. Stobaugh, 1994 .

Reversed-phase liquid chromatography of the opioid peptides. 3. Development of a microanalytical system for opioid peptides involving microbore liquid chromatography, post-column derivatization and laser-induced fluorescence detection.

T. Rossi, C. Riley, J. Stobaugh, 1992, Journal of pharmaceutical and biomedical analysis.

Multi-dimensional high-performance liquid chromatography of opioid peptides following pre-column derivatization with naphthalene-2,3-dicarboxaldehyde in the presence of cyanide ion. Preliminary results on the determination of leucine- and methionine-enkephalin-like fluorescence in the striatum regio

C. Riley, J. Stobaugh, D. K. Krehbiel, 1989, Journal of chromatography.

Chemical derivatization as a strategy to enhance detectability of agents used in cancer management.

T. J. Reid, L. Sternson, J. Stobaugh, 1988, Journal of pharmaceutical and biomedical analysis.

Aspects of the stability of isoindoles derived from the reaction of o-phthalaldehyde-ethanethiol with primary amino compounds.

L. Sternson, J. Stobaugh, A. Repta, 1986, Journal of pharmaceutical and biomedical analysis.

Rational design and evaluation of improved o-phthalaldehyde-like fluorogenic reagents.

L. Sternson, J. Stobaugh, A. Repta, 1985, Analytical biochemistry.

Selective fluorogenic derivatization of a peptide nucleic acid trimer with naphthalene-2,3-dicarboxaldehyde.

R. Borchardt, M. Rose, J. Stobaugh, 1997, Journal of pharmaceutical and biomedical analysis.

A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells.

T. Williams, M. Becker, J. Stobaugh, 2009, Rapid communications in mass spectrometry : RCM.

Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability

R. Gaedigk, M. Becker, J. Stobaugh, 2012, Pharmacogenetics and genomics.

Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle

J. Stobaugh, L. Haandel, 2010, Analytical and bioanalytical chemistry.

Synthesis of sulfonamide- and sulfonyl-phenylboronic acid-modified silica phases for boronate affinity chromatography at physiological pH.

C. Schöneich, J. Stobaugh, Justin Pennington, 2008, Analytical biochemistry.

Capillary electrophoresis separation of an asparagine containing hexapeptide and its deamidation products.

E. Topp, D. Skanchy, J. Stobaugh, 1998, Journal of pharmaceutical and biomedical analysis.

Resolution of acylated dipeptide stereoisomers by capillary electrophoresis using sulfobutylether derivatized β‐cyclodextrin

D. Skanchy, R. Wilson, J. Stobaugh, 1997, Electrophoresis.

Folate determination in human health: UPLC-MS/MS is the emerging methodology of choice.

J. Stobaugh, L. van Haandel, 2013, Bioanalysis.

Expedient methodology for total methotrexate polyglutamation pool determination in human erythrocytes

M. Becker, J. Stobaugh, A. Heemskerk, 2010 .

High performance liquid chromatographic method for the determination of homocysteine in human plasma using a water-soluble phosphine reducing agent and fluorogenic derivatization

J. Stobaugh, O. Wong, M. Whittle, 2000 .

Application of sulfobutylether‐β‐cyclodextrin with specific degrees of substitution for the enantioseparation of pharmaceutical mixtures by capillary electrophoresis

D. Skanchy, R. Tait, J. Stobaugh, 1999, Electrophoresis.

Chiral separations of enantiomeric pharmaceuticals by capillary electrophoresis using sulphobutyl ether beta-cyclodextrin as isomer selector.

D. Skanchy, J. Stobaugh, G. Xie, 1997, Biomedical chromatography : BMC.

Plasma analysis of alpha-difluoromethylornithine using pre-column derivatization with naphthalene-2,3-dicarboxaldehyde/CN and multidimensional chromatography.

M. Slavik, C. Riley, J. Stobaugh, 1998, Journal of pharmaceutical and biomedical analysis.

Comprehensive quantitative measurement of folate polyglutamates in human erythrocytes by ion pairing ultra-performance liquid chromatography/tandem mass spectrometry.

T. Williams, M. Becker, J. Stobaugh, 2012, Rapid communications in mass spectrometry : RCM.

Improved preparation and structural conformation of the fluorescence labelling reagents 1,2-diamino-4,5-dimethoxybenzene and 3,4-dihydro-6,7-dimethoxy-4-methyl-3-oxo-quinoxaline-2-carbonyl chloride.

C. Riley, J. Stobaugh, D. V. Vander Velde, 1990, Journal of pharmaceutical and biomedical analysis.

Synthesis and biological evaluation of gem-dichlorocyclopropyl and cyclopropyl analogs of stilbene congeners as potential antiestrogens.

J. Pento, R. A. Magarian, J. Stobaugh, 1982, Journal of pharmaceutical sciences.

A methodology for simultaneous fluorogenic derivatization and boronate affinity enrichment of 3-nitrotyrosine-containing peptides.

C. Schöneich, J. Stobaugh, V. Sharov, 2011, Analytical biochemistry.

Factors affecting the stability of fluorescent isoindoles derived from reaction of o-phthalaldehyde and hydroxyalkylthiols with primary amines.

L. Sternson, J. Stobaugh, K. Garren, 1983, Analytical biochemistry.

Naphthalene-2,3-dicarboxyaldehyde/cyanide ion: a rationally designed fluorogenic reagent for primary amines

R. Givens, T. Higuchi, L. Sternson, 1987 .

Characterization of sulphoalkyl ether derivatives of beta-cyclodextrin by capillary electrophoresis with indirect UV detection.

V. Stella, D. Skanchy, R. Tait, 1992, Journal of pharmaceutical and biomedical analysis.

Sulfobutyl Ether .beta.-Cyclodextrin as a Chiral Discriminator for Use with Capillary Electrophoresis

V. Stella, R. Tait, J. Stobaugh, 1994 .

Quantitative analysis of a model opioid peptide and its cyclic prodrugs in rat plasma using high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection.

R. Borchardt, J. Stobaugh, Jerry Z Yang, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Evaluation of the utility of capillary electrophoresis for the analysis of sulfobutyl ether beta-cyclodextrin mixtures.

V. Stella, R. Tait, R. Rajewski, 1996, Journal of pharmaceutical and biomedical analysis.

High-performance liquid chromatography of bis[1,2-bis-(diphenylphosphino)ethane]gold(I) chloride, a potential antineoplastic agent.

C. Riley, J. Stobaugh, F. W. Crouch, 1988, Journal of chromatography.

Hydroquinone-based derivatization reagents for the quantitation of amines using electrochemical detection.

S. Lunte, M. Rose, J. Stobaugh, 1999, Analytical chemistry.

Photodegradation Pathways of Protein Disulfides: Human Growth Hormone

Christian Schöneich, Y. J. Wang, C. Schöneich, 2017, Pharmaceutical Research.

Analysis of 5-flourouracil in plasma by precolumn derivatization with 4-bromomethyl-7-methoxycoumarin, followed by multi-dimensional high-performance liquid chromatography

M. Slavik, C. Riley, J. Stobaugh, 1989 .

High-performance liquid chromatography of 5-fluorouracil after derivatization with 4-bromomethyl-7-methoxycoumarin. Characterization of the derivative and the use of column switching for the improvement of resolution and the enhancement of sensitivity.

M. Slavik, C. Riley, J. Stobaugh, 1989, Journal of pharmaceutical and biomedical analysis.

Evaluation of 1.5 μm reversed phase nonporous silica in packed capillary electrochromatography and application in pharmaceutical analysis

J. Stobaugh, C. Demarest, T. Catalano, 1999 .

Aspects of column fabrication for packed capillary electrochromatography.

J. Stobaugh, C. Demarest, T. Catalano, 2000, Journal of chromatography. A.

Method development in pharmaceutical analysis employing capillary electrochromatography

J. Stobaugh, C. Demarest, T. Catalano, 1998, Electrophoresis.

LC-MS/MS method for the determination of carbamathione in human plasma.

M. D. Faiman, T. Williams, E. McCance-Katz, 2011, Journal of pharmaceutical and biomedical analysis.

Continuous in vivo monitoring of amino acid neurotransmitters by microdialysis sampling with on-line derivatization and capillary electrophoresis separation.

S. Lunte, C. Lunte, J. Stobaugh, 1995, Analytical chemistry.

Determination of spirogermanium (2-aza-8-germanspiro[4.5]-decane-2-propanamine-8,8-diethyl-N,N-dimethyl dichloride) by fluorometric ion-pair extraction. Application to the uniformity of content of solutions for intravenous injection.

M. Slavik, C. Riley, J. Stobaugh, 1989, Journal of pharmaceutical and biomedical analysis.

The Derivatization of Proquinoidal Analytes with 1,2-Diphenylethane-1,2-diamine (DPE) and Benzylamine (BA): An Investigation of Products, Yields, Kinetics and Reagent Selectivity

J. Stobaugh, Joshua Woods, Justin Pennington, 2015, Chromatographia.

Selective Fluorogenic Derivatization with Isotopic Coding of Catechols and 2-Amino Phenols with Benzylamine: A Chemical Basis for the Relative Determination of 3-Hydroxy-tyrosine and 3-Nitro-tyrosine Peptides

C. Schöneich, J. Stobaugh, Justin Pennington, 2007 .

Automated analytical systems for drug development studies. I--A system for the determination of drug stability.

M Slavik, R. Schowen, M. Slavik, 1994, Journal of pharmaceutical and biomedical analysis.

Liquid chromatographic determination of cyclophosphamide enantiomers in plasma by precolumn chiral derivatization.

J. M. Reid, L. Sternson, J. Stobaugh, 1989, Analytical chemistry.

Stereoselective pharmacokinetics and metabolism of the enantiomers of cyclophosphamide. Preliminary results in humans and rabbits.

M. Slavik, C. Riley, J. Stobaugh, 1990, Biochemical pharmacology.

Determination of intracellular levels of 6-mercaptopurine metabolites in erythrocytes utilizing capillary electrophoresis with laser-induced fluorescence detection.

J. Stobaugh, R. Trueworthy, S. Rabel, 1995, Analytical biochemistry.

A Clinical Method for the Analysis of Amygdalin in Human Plasma

L. Sternson, J. Stobaugh, A. Repta, 1978 .

Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations.

R. Gaedigk, M. Becker, J. Stobaugh, 2010, Arthritis and rheumatism.

On-line coupling of in vivo microdialysis sampling with capillary electrophoresis.

S. Lunte, C. Lunte, B L Hogan, 1994, Analytical chemistry.

The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response.

Hongying Dai, Roger Gaedigk, Bradley Thomas, 2011, Arthritis and rheumatism.

Stability of intravenous admixtures of 5-fluorouracil and spirogermanium, a novel combination of cytotoxic agents

M. Slavik, C. Riley, J. Stobaugh, 1990 .

Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle

J. Stobaugh, L. Haandel, 2010, Analytical and bioanalytical chemistry.

Selective fluorogenic derivatization of Pro2—Lys peptides with naphthalene-2,3-dicarboxaldehyde/cyanide

J. Stobaugh, F. Kristjánsson, A. Thakur, 1992 .