I. Hemmilä

发表

Solid-phase immunoassay of digoxin by measuring time-resolved fluorescence.

T. Lövgren, P. Helsingius, I. Hemmilä, 1986, Clinical chemistry.

Double-label time-resolved immunofluorometry of lutropin and follitropin in serum.

Kim Pettersson, Ilkka Hemmilä, K. Pettersson, 1987, Clinical chemistry.

Profiling the hydA gene and hydA gene transcript levels of Clostridium butyricum during continuous, mixed-culture hydrogen fermentation

P. Koskinen, M. Karp, Ville Santala, 2008 .

A new sensitive assay of human alpha-fetoprotein using time-resolved fluorescence and monoclonal antibodies.

T. Lövgren, I. Hemmilä, M. Suonpää, 1985, Clinica chimica acta; international journal of clinical chemistry.

Detection of viral antigens by time-resolved fluoroimmunoassay.

T. Lövgren, E. Soini, I. Hemmilä, 1983, Current topics in microbiology and immunology.

Determination of cytotoxic T lymphocyte activity by time-resolved fluorometry using europium-labelled concanavalin A-stimulated cells as targets.

T. Lövgren, C. Granberg, I. Hemmilä, 1988, Journal of immunological methods.

Micelle Stabilized Phosphorescent Immunoassay Based on Bispecific Antibodies Against Label and Antigen

A. Savitsky, B. Micheel, I. Hemmilä, 1995 .

A versatile method for quantification of DNA and PCR products based on time-resolved EuIII luminescence.

J. Bünzli, C. Vandevyver, Bo Song, 2008, The Analyst.

Nonradioactive GTP binding assay to monitor activation of g protein-coupled receptors.

M. Scheinin, P. Hurskainen, I. Hemmilä, 2003, Assay and drug development technologies.

Two-site time-resolved immunofluorometric assay of human insulin.

J. Zeuthen, J. Marniemi, T. Lövgren, 1986, Clinical chemistry.

Homogeneous assay based on anti-Stokes' shift time-resolved fluorescence resonance energy-transfer measurement.

I. Hemmilä, V. Laitala, 2005, Analytical chemistry.

Lanthanide chelates as new fluorochrome labels for cytochemistry.

L. Pelliniemi, J. Kankare, E. Soini, 1988, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Influence of coupling method on the luminescence properties, coupling efficiency, and binding affinity of antibodies labeled with europium (III) chelates.

K. Pettersson, T. Lövgren, A. Toivonen, 1997, Bioconjugate chemistry.

Determination of hormones by time-resolved fluoroimmunoassay.

E. Bertoft, K. Pettersson, T. Lövgren, 1984, Talanta.

Europium-labelled target cells in an assay of natural killer cell activity. I. A novel non-radioactive method based on time-resolved fluorescence.

T. Lövgren, C. Granberg, I. Hemmilä, 1986, Journal of immunological methods.

Development of a Ubiquitin Transfer Assay for High Throughput Screening by Fluorescence Resonance Energy Transfer

S. Josiah, M. Boisclair, I. Hemmilä, 2000, Journal of biomolecular screening.

Time-resolved fluoroimmunoassay: a new test for rubella antibodies

T. Lövgren, I. Hemmilä, O. Meurman, 1982, Journal of clinical microbiology.

Caspase multiplexing: simultaneous homogeneous time-resolved quenching assay (TruPoint) for caspases 1, 3, and 6.

H. Hakala, J. Hovinen, P. Hurskainen, 2004, Analytical biochemistry.

Europium-labelled target cells in an assay of natural killer cell activity. II. A novel non-radioactive method based on time-resolved fluorescence. significance and specificity of the method.

T. Lövgren, C. Granberg, I. Hemmilä, 1986, Journal of immunological methods.

Homogeneous Time-Resolved Fluorescence Quenching Assay (LANCE) for Caspase-3

U. Warrior, D. Burns, P. Hurskainen, 2002, Journal of biomolecular screening.

Development of luminescent lanthanide chelate labels for diagnostic assays

I. Hemmilä, H. Takalo, V. Mukkala, 1997 .

SYNTHESIS AND LUMINESCENCE OF NOVEL EUIII COMPLEXING AGENTS AND LABELS WITH 4-(PHENYLETHYNYL)PYRIDINE SUBUNITS

I. Hemmilä, H. Takalo, M. Latva, 1996 .

Co-fluorescence effect in time-resolved fluoroimmunoassays. A review.

T. Lövgren, I. Hemmilä, Y. Y. Xu, 1992, The Analyst.

Co-fluorescence enhancement system based on pivaloyltrifluoroacetone and yttrium for the simultaneous detection of europium, terbium, samarium and dysprosium

I. Hemmilä, Yongqian Xu, 1992 .

A Cell-Based DNA Fragmentation Assay in Microplate Format using DELFIA ® Technology

P. Hurskainen, I. Hemmilä, H. Frang, 2002 .

Europium as a label in time-resolved immunofluorometric assays.

T. Lövgren, H. Siitari, I Hemmilä, 1984, Analytical biochemistry.

Fluoroimmunoassay: present status and key problems.

I Hemmilä, E Soini, E. Soini, 1979, Clinical chemistry.

Progress in Lanthanides as Luminescent Probes

I. Hemmilä, I. Hemmilä, V. Laitala, 2005, Journal of Fluorescence.

Novel Thiazole‐Containing Complexing Agents and Luminescence of Their Europum(III) and Terbium(III) Chelates

J. Kankare, I. Hemmilä, H. Takalo, 1996 .

Synthesis and luminescence properties of some Eu(III) and Tb(III) chelate labels having 2,2′:6′,2″-terpyridine as an energy absorbing part

I. Hemmilä, H. Takalo, V. Mukkala, 1995 .

Homogeneous assay based on low quantum yield Sm(III)-donor and anti-Stokes’ shift time-resolved fluorescence resonance energy-transfer measurement

I. Hemmilä, V. Laitala, 2005 .

Comparison of homogeneous single-label fluorometric binding assays: fluorescence polarization and dual-parametric quenching resonance energy transfer technique.

P. Hänninen, H. Härmä, I. Hemmilä, 2010, Analytical chemistry.

Effect of C-H bonds on the quenching of luminescent lanthanide chelates

I. Hemmilä, H. Takalo, V. Mukkala, 1995, Journal of Fluorescence.

Lanthanides as probes for time-resolved fluorometric immunoassays.

I Hemmilä, I. Hemmilä, 1988, Scandinavian journal of clinical and laboratory investigation.

Bioconjugated lanthanide luminescent helicates as multilabels for lab-on-a-chip detection of cancer biomarkers.

M. Gijs, H. Lehr, J. Bünzli, 2010, The Analyst.

Time-resolved fluoroimmunoassay of human choriogonadotropin.

U. Stenman, K. Pettersson, T. Lövgren, 1983, Clinical chemistry.

Expression of the tumour-associated antigen CA-242 in transitional cell bladder tumours: a comparison with CA-50.

P. Lipponen, I. Hemmilä, M. Eskelinen, 1993, European journal of cancer.

Europium-labelled streptavidin as a highly sensitive universal label. Indirect time-resolved immunofluorometry of FSH and TSH.

I. Hemmilä, M. Suonpää, T. Ståhlberg, 1992, Journal of immunological methods.

Time-Resolved Fluorometric Immunoassays; Instrumentation, Applications, Unresolved Issues and Future Trends

Ilkka Hemmilä, I. Hemmilä, 2008 .

Fluoroimmunoassays and immunofluorometric assays.

I Hemmilä, I. Hemmilä, 1985, Clinical chemistry.

Time-resolved fluoroimmunoassay (TR-FIA) of tetanus antibodies

T. Lövgren, I. Hemmilä, M. Viljanen, 1984 .

Time-resolved europium fluorescence in enzyme activity measurements: a sensitive protease assay.

M. Karp, P. Mäntsälä, I. Hemmilä, 1983, Journal of applied biochemistry.

Detection of hepatitis B surface antigen using time-resolved fluoroimmunoassay

V. Koistinen, T. Lövgren, H. Siitari, 1983, Nature.

Analytical application of the co-fluorescence effect in detection of europium, terbium, samarium and dysprosium with time-resolved fluorimetry.

I. Hemmilä, Y. Y. Xu, 1992, Talanta.

Applications of Fluorescence in Immunoassays

I. Hemmilä, 1991 .

Genotyping of celiac disease-related-risk haplotypes using a closed-tube polymerase chain reaction analysis of dried blood and saliva disk samples.

J. Hovinen, I. Hemmilä, Hanna-Mari Raussi, 2009, Analytical biochemistry.

Quantitative monitoring of a hydrogen-producing Clostridium butyricum strain from a continuous-flow, mixed culture bioreactor employing real-time PCR

P. Koskinen, J. Puhakka, M. Karp, 2008 .

Time-resolved detection probe for homogeneous nucleic acid analyses in one-step format.

Ilkka Hemmilä, I. Hemmilä, Ville Laitala, 2007, Analytical biochemistry.

Homogeneous time-resolved fluorescence quenching assay (TruPoint) for nucleic acid detection.

H. Hakala, J. Hovinen, I. Hemmilä, 2004, Clinical chemistry.

Time-resolved fluorometric determination of terbium in aqueous solution

I. Hemmilä, 1985 .

Time-resolved fluorimetry in the study of attachment of staphylococci and streptococci on substrate-bound fibronectin

M. Vuento, I. Hemmilä, E. Myhre, 1986 .

Time-Resolved FRET -Based Approach for Antibody Detection – A New Serodiagnostic Concept

A. Vaheri, J. Hepojoki, O. Vapalahti, 2013, PloS one.

Novel detection strategies for drug discovery.

P. Hurskainen, I. Hemmilä, 2002, Drug discovery today.

LANCE™: Homogeneous Assay Platform for HTS

I. Hemmilä, 1999 .

Time-resolved fluorescence imaging of europium chelate label in immunohistochemistry and in situ hybridization.

R Harju, S. Syrjänen, A. Kuusisto, 1992, Cytometry.

Simultaneous quadruple-label fluorometric immunoassay of thyroid-stimulating hormone, 17 alpha-hydroxyprogesterone, immunoreactive trypsin, and creatine kinase MM isoenzyme in dried blood spots.

K. Pettersson, T. Lövgren, H. Mikola, 1992, Clinical chemistry.

Homogeneous time-resolved fluoroimmunoassay of thyroxin in serum.

T. Lövgren, H. Mikola, I. Hemmilä, 1988, Clinical chemistry.

Progress in Delayed Fluorescence Immunoassay

I. Hemmilä, 1993 .

Purification and properties of glutamate synthase and glutamate dehydrogenase from Bacillus megaterium.

P. Mäntsälä, I. Hemmilä, 1978, The Biochemical journal.

Development of solid-phase immunoassay using chemiluminescent IgG conjugates.

T. Lövgren, I. Hemmilä, P. 0. Cheng, 1982, Journal of immunological methods.

A dissociative fluorescence enhancement technique for one-step time-resolved immunoassays

H. Hakala, I. Hemmilä, V. Mukkala, 2010, Analytical and Bioanalytical Chemistry.

16 Development of Nuclear Receptor Homogeneous Assay Using the LANCE TM Technology

N. Rouleau, R. Bossé, P. Hurskainen, 2006 .

Time-resolved fluorometry: an overview of the labels and core technologies for drug screening applications

Ilkka Hemmilä, I. Hemmilä, S. Webb, 1997 .

Di- and tetracarboxylate derivatives of pyridines, bipyridines and terpyridines as luminogenic reagents for time-resolved fluorometric determination of terbium and dysprosium.

I. Hemmilä, P. Kiilholma, V. Mukkala, 1993, Journal of biochemical and biophysical methods.

A New Simple Cell-Based Homogeneous Time-Resolved Fluorescence QRET Technique for Receptor-Ligand Interaction Screening

M. Perälä, P. Hänninen, H. Härmä, 2009, Journal of biomolecular screening.

Luminescent lanthanide chelates—a way to more sensitive diagnostic methods

I. Hemmilä, I. Hemmilä, 1995 .

Terbium and rhodamine as labels in a homogeneous time-resolved fluorometric energy transfer assay of the beta subunit of human chorionic gonadotropin in serum.

P. Hurskainen, I. Hemmilä, K. Blomberg, 1999, Clinical chemistry.

Europium-labelled recombinant protein G. A fast and sensitive universal immunoreagent for time-resolved immunofluorometry.

I. Hemmilä, T. Ståhlberg, E. Markela, 1993, JIM - Journal of Immunological Methods.

Time-resolved fluoroimmunoassay (TR-FIA)

T. Lövgren, E. Soini, I. Hemmilä, 1982 .

Co-fluorescence of europium and samarium in time-resolved fluorimetric immunoassays.

T. Lövgren, I Hemmilä, V M Mukkala, 1991, The Analyst.

Simultaneous quantification of two plant viruses by double-label time-resolved immunofluorometric assay.

H. Siitari, I. Hemmilä, L. Järvekülg, 1989, Journal of virological methods.

Lanthanide Chelates as New Fluorochrome Labels for

L. Pelliniemi, J. Kankare, E. Soini, 1988 .

Fluorescence quenching-based assays for hydrolyzing enzymes. Application of time-resolved fluorometry in assays for caspase, helicase, and phosphatase.

Johanna Tamminen, Jarkko Karvinen, Pertti Hurskainen, 2004, Analytical chemistry.

Homogeneous GTP Binding Assay Employing QRET Technology

M. Scheinin, P. Hänninen, H. Härmä, 2010, Journal of biomolecular screening.

HOMOGENEOUS TIME-RESOLVED IL-2–IL-2Rα ASSAY USING FLUORESCENCE RESONANCE ENERGY TRANSFER

Pertti Hurskainen, Ilkka Hemmilä, S. Eriksson, 1998 .

Use of fluorescent europium chelates as labels in microscopy allows glutaraldehyde fixation and permanent mounting and leads to reduced autofluorescence and good long‐term stability

I Hemmilä, E Soini, E. Soini, 1994, Microscopy research and technique.