J. Hinson

发表

Synthesis and analysis of glucuronides of N-hydroxyamides.

C. Fenselau, P. Feng, M. Colvin, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Bromobenzene and p-bromophenol toxicity and covalent binding in vivo.

T. Monks, J. Hinson, J. Gillette, 1982, Life sciences.

Stereoselective formation of bromobenzene glutathione conjugates.

J R Gillette, J. Ferretti, T. Monks, 1982, Chemico-biological interactions.

Studies on the microsomal formation of arylating metabolites of acetaminophen and phenacetin.

S. Nelson, J. Hinson, J. Mitchell, 1977, Molecular pharmacology.

The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride.

T. Monks, L. Pohl, J. Hinson, 1981, Drug metabolism and disposition: the biological fate of chemicals.

Reactive metabolites of phenacetin and acetaminophen: a review

J. Hinson, 1983, Environmental health perspectives.

p-Nitrosophenetole: a reactive intermediate of phenacetin that binds to protein.

J. Hinson, J. B. Mays, 1986, Advances in experimental medicine and biology.

Microsomal N-Hydroxylation of p-Chloroacetanilide

D. Jollow, J. Hinson, Jerry R. Mitchell, 1975 .

N-hydroxylation of p-chloroacetanilde in hamsters.

D. Jollow, J. Hinson, J. Mitchell, 1976, Biochemical pharmacology.

N-Hydroxylation of phenacetin by hamster liver microsomes.

J. Hinson, J. Mitchell, 1976, Drug metabolism and disposition: the biological fate of chemicals.

Generation of reactive metabolites of N-hydroxy-phenacetin by glucoronidation and sulfation.

J R Gillette, G. Mulder, G J Mulder, 1977, Biochemical pharmacology.

Conversion of the N-Q-glucuronide and N-O-sulfate conjugates of N-hydroxyphenacetin to reactive intermediates.

G. Mulder, J. Hinson, J. Gillette, 1978, Biochemical pharmacology.

N-Hydroxyacetaminophen: a microsomal metabolite of N-hydroxyphenacetin but apparently not of acetaminophen.

L. Pohl, J. Hinson, J. Gillette, 1979, Life sciences.

Kinetic evidence for multiple chemically reactive intermediates in the breakdown of phenacetin N-O-glucuronide.

J. Hinson, J. Gillette, L. Andrews, 1979, Pharmacology.

Metabolism of [p-18O]-phenacetin: the mechanism of activation of phenacetin to reactive metabolites in hamsters.

S. Nelson, J. Hinson, J. Gillette, 1979, Molecular pharmacology.

The formation of arylating and alkylating metabolites of phenacetin in hamsters and hamster liver microsomes.

Y. Vaishnav, S. Nelson, J. Hinson, 1981, Molecular pharmacology.

Acetaminophen-induced hepatotoxicity.

J R Gillette, T. Monks, L. Pohl, 1981, Life sciences.

In Vivo Mechanisms of Tissue-Selective Drug Toxicity: Effects of Liver-Specific Knockout of the NADPH-Cytochrome P450 Reductase Gene on Acetaminophen Toxicity in Kidney, Lung, and Nasal Mucosa

H. Cui, Qing-Yu Zhang, M. Behr, 2005, Molecular Pharmacology.

Mechanisms of acetaminophen-induced liver necrosis.

L. James, J. Hinson, D. Roberts, 2010, Handbook of experimental pharmacology.

Mechanisms of Acetaminophen-Induced Liver Disease

J. Hinson, Jack A. Hinson, 2013 .

Mouse Liver Protein Sulfhydryl Depletion after Acetaminophen Exposure

James Greenhaw, Xi Yang, Qiang Shi, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Formation of chemically reactive metabolites of phenacetin and acetaminophen.

G. Mulder, L. Pohl, S. Nelson, 1981, Advances in experimental medicine and biology.

A sensitive immunochemical assay for acetaminophen-protein adducts.

N. Pumford, J. Hinson, D. Roberts, 1987, The Journal of pharmacology and experimental therapeutics.

The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study.

P. Wardman, B. Ketterer, S. Nelson, 1988, Archives of biochemistry and biophysics.

Immunochemical quantitation of 3-(cystein-S-yl)acetaminophen adducts in serum and liver proteins of acetaminophen-treated mice.

N. Pumford, J. Hinson, D. Roberts, 1989, The Journal of pharmacology and experimental therapeutics.

Mechanism of paracetamol toxicity

S. Loft, H. Poulsen, K. Dalhoff, 1990, The Lancet.

Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice.

N. Pumford, P. R. Mayeux, J. Hinson, 1998, Chemical research in toxicology.

Deferoxamine delays the development of the hepatotoxicity of acetaminophen in mice.

D. Kusewitt, N. Pumford, J. Hinson, 1999, Toxicology letters.

Elevation of serum interleukin 8 levels in acetaminophen overdose in children and adolescents

H. Farrar, G. Kearns, P. Simpson, 2001, Clinical pharmacology and therapeutics.

Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice.

P. R. Mayeux, J. Hinson, T. Bucci, 2002, Nitric oxide : biology and chemistry.

Interleukin 6 and hepatocyte regeneration in acetaminophen toxicity in the mouse.

L. James, J. Hinson, L. Lamps, 2003, Biochemical and biophysical research communications.

Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression.

R. Kurten, L. James, J. Hinson, 2005, Basic & clinical pharmacology & toxicology.

Vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity.

P. Simpson, R. Kurten, L. James, 2006, American journal of physiology. Gastrointestinal and liver physiology.

The development and hepatotoxicity of acetaminophen: reviewing over a century of progress

Mitchell R. McGill, J. Hinson, 2020, Drug metabolism reviews.

Immunochemical detection of drug-protein adducts in acetaminophen hepatotoxicity.

N. Pumford, J. Hinson, D. Roberts, 1996, Advances in experimental medicine and biology.

Mechanisms of acetaminophen toxicity: immunochemical detection of drug-protein adducts.

N. Pumford, J. Hinson, D. Roberts, 1995, Drug metabolism reviews.

The role of metabolic activation in drug toxicity.

S. Nelson, N. Pumford, J. Hinson, 1994, Drug metabolism reviews.

Acetaminophen-induced alterations in pancreatic beta cells and serum insulin concentrations in B6C3F1 mice.

J. Hinson, D. Roberts, R. W. Benson, 1990, Toxicology and applied pharmacology.

Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice.

P. Simpson, L. James, J. Hinson, 2012, Toxicology and applied pharmacology.

Biotransformation of drugs.

J. Hinson, J. Gillette, Jack A. Hinson, 1978, Advances in experimental medicine and biology.

Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress.

L. James, J. Hinson, S. McCullough, 2006, Biochemical and biophysical research communications.

Immunochemical detection of oxidized proteins.

R. J. Keller, N. Pumford, J. Hinson, 1993, Chemical research in toxicology.

Echinomycin decreases induction of vascular endothelial growth factor and hepatocyte regeneration in acetaminophen toxicity in mice.

R. Kurten, A. Milesi-Hallé, L. James, 2012, Basic & clinical pharmacology & toxicology.

Covalent binding of acetaminophen to N-10-formyltetrahydrofolate dehydrogenase in mice.

B. Martin, R. Cook, N. Pumford, 1997, The Journal of pharmacology and experimental therapeutics.

Detection of Acetaminophen Protein Adducts in Children With Acute Liver Failure of Indeterminate Cause

William M. Lee, T. Davern, L. Hynan, 2006, Pediatrics.

Acetaminophen-induced hepatotoxicity. Analysis of total covalent binding vs. specific binding to cysteine.

N. Pumford, J. Hinson, D. Roberts, 1996, Drug metabolism and disposition: the biological fate of chemicals.

Measurement of Acetaminophen‐Protein Adducts in Children and Adolescents with Acetaminophen Overdoses

H. Farrar, G. Kearns, P. Walson, 2001, Journal of clinical pharmacology.

Acetaminophen peroxidation reactions.

J. Hinson, D. W. Potter, D. Potter, 1989, Drug metabolism reviews.

Immunochemical comparison of 3'-hydroxyacetanilide and acetaminophen binding in mouse liver.

S. Roberts, N. Pumford, W. Salminen, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Western blot analysis for nitrotyrosine protein adducts in livers of saline-treated and acetaminophen-treated mice.

N. Pumford, J. Hinson, S. L. Michael, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Mechanisms of Chloroform-Induced Hepatotoxicity: Oxidative Stress and Mitochondrial Permeability Transition in Freshly Isolated Mouse Hepatocytes

R. Kurten, L. James, J. Hinson, 2007, Journal of toxicology and environmental health. Part A.

Horseradish peroxidase-catalyzed oxidation of acetaminophen to intermediates that form polymers or conjugate with glutathione.

D. Miller, J. Hinson, D. W. Potter, 1986, Molecular pharmacology.

Acetaminophen hepatotoxicity and HIF-1 α induction in mice occurs without hypoxia

P. Simpson, J. Hinson, L. Hennings, 2011 .

FORUM Mechanisms of Hepatotoxicity

G. Gores, H. Jaeschke, D. Pessayre, 2002 .

Are oxidative mechanisms primary in ethanol induced Purkinje neuron death of the neonatal rat?

J. Hinson, K. Light, D. Pierce, 2006, Neuroscience Letters.

Utility of solution electrochemistry mass spectrometry for investigating the formation and detection of biologically important conjugates of acetaminophen.

Walter A. Korfmacher, J. Hinson, T. Getek, 1989, Journal of chromatography.

Glutamate dehydrogenase covalently binds to a reactive metabolite of acetaminophen.

B. Martin, N. Pumford, J. Hinson, 1996, Chemical research in toxicology.

Immunochemical quantitation of 3-(cystein-S-yl)acetaminophen protein adducts in subcellular liver fractions following a hepatotoxic dose of acetaminophen.

N. Pumford, J. Hinson, D. Roberts, 1990, Biochemical pharmacology.

A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein.

B. Martin, N. Pumford, J. Hinson, 1992, Biochemical and biophysical research communications.

Direct analysis of rat bile for acetaminophen and two of its conjugated metabolites via thermospray liquid chromatography/mass spectrometry.

Walter A. Korfmacher, J. Lay, J. Hinson, 1987, Biomedical & environmental mass spectrometry.

Haemoglobin adducts as biomarkers of exposure to the herbicides propanil and fluometuron.

J. Lay, J. Freeman, J. Hinson, 1996, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Acylcarnitine Profiles in Acetaminophen Toxicity in the Mouse: Comparison to Toxicity, Metabolism and Hepatocyte Regeneration

S. Bhattacharyya, R. Beger, P. Simpson, 2013, Metabolites.

3-Hydroxyacetaminophen: a microsomal metabolite of acetaminophen. Evidence against an epoxide as the reactive metabolite of acetaminophen.

F. Guengerich, T. Monks, L. Pohl, 1980, Drug metabolism and disposition: the biological fate of chemicals.

Propanil-induced methemoglobinemia and hemoglobin binding in the rat.

D. McMillan, J. Hinson, T. A. McRae, 1990, Toxicology and applied pharmacology.

19 – Pharmacokinetic Aspects of the Formation and Inactivation of Chemically Reactive Metabolites

J. Hinson, J. Gillette, L. Andrews, 1978 .

Evaluation of Occult Acetaminophen Hepatotoxicity in Hospitalized Children Receiving Acetaminophen

H. Farrar, G. Kearns, N. Pumford, 2001, Clinical pediatrics.

Covalent binding of xenobiotics to specific proteins in the liver.

N. Pumford, J. Hinson, N. C. Halmes, 1997, Drug metabolism reviews.

A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids.

L. Pohl, J. Hinson, J. Gillette, 1980, Analytical biochemistry.

Human Recombinant Vascular Endothelial Growth Factor Reduces Necrosis and Enhances Hepatocyte Regeneration in a Mouse Model of Acetaminophen Toxicity

P. Simpson, A. Saad, R. Kurten, 2010, Journal of Pharmacology and Experimental Therapeutics.

Advances in biomarker development in acetaminophen toxicity.

William M. Lee, Mitchell R. McGill, L. James, 2020, Advances in clinical chemistry.

Acetaminophen‐Associated Hepatic Injury: Evaluation of Acetaminophen Protein Adducts in Children and Adolescents With Acetaminophen Overdose

G. Kearns, P. Simpson, E. Capparelli, 2008, Clinical pharmacology and therapeutics.

Reaction of mutagenic phenacetin metabolites with glutathione and DNA. Possible implications for toxicity.

G. Mulder, F. Kadlubar, J. Hinson, 1984, Molecular pharmacology.

Identification of acetaminophen polymerization products catalyzed by horseradish peroxidase.

D. Miller, J. Hinson, D. W. Potter, 1985, The Journal of biological chemistry.

Application of chemical ionization mass spectrometry and the twin-ion technique to better define a mechanism in acetylhydrazine toxicity.

S. Nelson, J. Hinson, J. Mitchell, 1976, Biochemical and biophysical research communications.

An examination of octanol and octanal metabolism to octanoic acid by horse liver alcohol dehydrogenase.

R. A. Neal, J. Hinson, 1975, Biochimica et biophysica acta.

Toxic Drug Reactions

W. Potter, J. Timbrell, J. Hinson, 1975 .

Propanil : toxicological characteristics, metabolism, and biodegradation potential in soil

C. Cerniglia, J. Hinson, J. V. Pothuluri, 1991 .

Cytokines and Toxicity in Acetaminophen Overdose

H. Farrar, G. Kearns, P. Simpson, 2005, Journal of clinical pharmacology.

The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes.

S. Melnyk, N. Aykin-Burns, L. James, 2015, Free radical biology & medicine.

Acetaminophen-Induced Hepatotoxicity and Protein Nitration in Neuronal Nitric-Oxide Synthase Knockout Mice

L. MacMillan-Crow, L. James, J. Hinson, 2012, Journal of Pharmacology and Experimental Therapeutics.

Role of metabolites in propanil-induced hemolytic anemia.

D. McMillan, D. Jollow, J. Hinson, 1991, Toxicology and applied pharmacology.

Contribution of 3,4-dichlorophenylhydroxylamine in propanil-induced hemolytic anemia.

J. McMillan, D. McMillan, D. Jollow, 1991, Advances in experimental medicine and biology.

Trifluoperazine inhibits acetaminophen-induced hepatotoxicity and hepatic reactive nitrogen formation in mice and in freshly isolated hepatocytes

S. Melnyk, N. Aykin-Burns, L. James, 2017, Toxicology reports.

Antagonism of bromobenzene-induced hepatotoxicity by phentolamine: evidence for a metabolism-independent intervention.

R. Harbison, S. Roberts, B. Kerger, 1988, Toxicology and applied pharmacology.

Role of sulfotransferase from rat liver in the mutagenicity of N-hydroxy-2-acetylaminofluorene in Salmonella typhimurium

W. L. Nelson, S. Thorgeirsson, G. Mulder, 1977 .

Mechanisms of Acetaminophen-Induced Hepatotoxicity: Role of Oxidative Stress and Mitochondrial Permeability Transition in Freshly Isolated Mouse Hepatocytes

R. Kurten, J. Hinson, Angela B Reid, 2005, Journal of Pharmacology and Experimental Therapeutics.

Studies on the mutagenicity of N-hydroxy-2-acetylaminofluorene in the Ames-Salmonella mutagenesis test system.

L. S. Andrews, J. Hinson, J. Gillette, 1978, Biochemical pharmacology.

Acetaminophen-induced hepatotoxicity.

Laura P James, Philip R Mayeux, Jack A Hinson, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Acetaminophen‐Induced Hepatotoxicity: Role of Metabolic Activation, Reactive Oxygen/Nitrogen Species, and Mitochondrial Permeability Transition

Laura P James, Jack A Hinson, L. James, 2004, Drug metabolism reviews.

Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation.

L. James, J. Hinson, L. Lamps, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Measurement of serum acetaminophen-protein adducts in patients with acute liver failure.

William M. Lee, R. Fontana, T. Davern, 2006, Gastroenterology.

Mechanism of acetaminophen-induced hepatotoxicity: covalent binding versus oxidative stress.

N. Pumford, J. Hinson, J D Gibson, 1996, Chemical research in toxicology.

Role of covalent and noncovalent interactions in cell toxicity: effects on proteins.

J. Hinson, D. Roberts, D W Roberts, 1992, Annual review of pharmacology and toxicology.

Selective protein covalent binding and target organ toxicity.

Steven D. Cohen, K. Boekelheide, L. Pohl, 1997, Toxicology and applied pharmacology.

Mechanisms of hepatotoxicity.

G. Gores, H. Jaeschke, D. Pessayre, 2002, Toxicological sciences : an official journal of the Society of Toxicology.

An examination of the oxidation of aldehydes by horse liver alcohol dehydrogenase.

R. A. Neal, J. Hinson, 1972, The Journal of biological chemistry.

Metabolism of the arylamide herbicide propanil. I. Microsomal metabolism and in vitro methemoglobinemia.

J. Freeman, D. McMillan, J. Hinson, 1990, Toxicology and applied pharmacology.

Determination of acetaminophen-protein adducts in mouse liver and serum and human serum after hepatotoxic doses of acetaminophen using high-performance liquid chromatography with electrochemical detection.

K. Muldrew, H. Hendrickson, Laura P James, 2002, Drug metabolism and disposition: the biological fate of chemicals.

Hepatic necrosis caused by furosemide

W. Potter, D. Jollow, J. Hinson, 1974, Nature.

Ascorbic acid inhibits covalent binding of enzymatically generated 2-acetyl-aminofluororene-N-sulfate to DNA under conditions in which it increases mutagenesis in salmonella TA-1538.

L. S. Andrews, J. Hinson, J. Gillette, 1979, Life Science.

Functional importance of ICAM-1 in the mechanism of neutrophil-induced liver injury in bile duct-ligated mice.

H. Jaeschke, Jie Liu, A. Farhood, 2004, American journal of physiology. Gastrointestinal and liver physiology.

The 1- and 2-electron oxidation of acetaminophen catalyzed by prostaglandin H synthase.

J. Hinson, D. Potter, 1987, The Journal of biological chemistry.

The acetaminophen regioisomer 3'-hydroxyacetanilide inhibits and covalently binds to cytochrome P450 2E1.

N. Pumford, J. Hinson, N. C. Halmes, 1998, Toxicology letters.

Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia.

Pippa M Simpson, Leah Hennings, P. Simpson, 2011, Toxicology and applied pharmacology.

Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

William M. Lee, T. Davern, P. Simpson, 2009, Drug Metabolism and Disposition.

Immunohistochemical localization and quantification of the 3-(cystein-S-yl)-acetaminophen protein adduct in acetaminophen hepatotoxicity.

T J Bucci, N. Pumford, A. Warbritton, 1991, The American journal of pathology.

Acetaminophen toxicity to cultured rat embryos.

E. Khairallah, J. Hinson, M. Bruno, 1990, Teratogenesis, carcinogenesis, and mutagenesis.

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

N. Pumford, J. Hinson, S. L. Michael, 1999, Hepatology.

An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure

William M. Lee, R. Fontana, D. Ganger, 2017, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

3-(glutathion-S-yl)acetaminophen: a biliary metabolite of acetaminophen.

T. Monks, L. Pohl, J. Hinson, 1982, Drug metabolism and disposition: the biological fate of chemicals.

Acetaminophen-induced hepatic glycogen depletion and hyperglycemia in mice.

J. Hinson, A. Cameron, J. B. Mays, 1983, Biochemical pharmacology.

2,6-Dimethylaniline--hemoglobin adducts from lidocaine in humans.

R. E. Harrell, M. Bryant, J. Hinson, 1994, Carcinogenesis.

784 Serum acetaminophen adducts reliably distinguish acetaminophen toxicity from other causes of acute liver failure

R. Fontana, A. Larson, L. James, 2003 .

Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice.

N. Pumford, J. Hinson, D. Roberts, 1990, Toxicology and applied pharmacology.

Pretreatment with mixed‐function oxidase inducers increases the sensitivity of the hepatocyte/DNA repair assay

J. Shaddock, D. Casciano, D. McMillan, 1989, Environmental and molecular mutagenesis.

Comparison of covalent binding of acetaminophen and the regioisomer 3'-hydroxyacetanilide to mouse liver protein.

N. Pumford, J. Hinson, D. Roberts, 1997, Toxicology letters.

Epitope characterization of acetaminophen bound to protein and nonprotein sulfhydryl groups by an enzyme-linked immunosorbent assay.

N. Pumford, J. Hinson, D. Roberts, 1989, The Journal of pharmacology and experimental therapeutics.

Acetaminophen-induced alterations in blood glucose and blood insulin levels in mice.

S. J. Holt, B. Ketterer, P. Mclean, 1984, Research communications in chemical pathology and pharmacology.

Reactions of glutathione with oxidative intermediates of acetaminophen.

J. Hinson, D. Potter, 1986, Advances in experimental medicine and biology.

Metabolism of the arylamide herbicide propanil. II. Effects of propanil and its derivatives on hepatic microsomal drug-metabolizing enzymes in the rat.

M. P. Arlotto, J. McMillan, D. McMillan, 1990, Toxicology and applied pharmacology.

Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress.

J. Hinson, M. Bajt, H. Jaeschke, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Changes in Mouse Liver Protein Glutathionylation after Acetaminophen Exposure

Jinchun Sun, James Greenhaw, Xi Yang, 2012, Journal of Pharmacology and Experimental Therapeutics.

Oxidant stress in rat liver after lipopolysaccharide administration: effect of inducible nitric-oxide synthase inhibition.

J. Hinson, C. Zhang, L. M. Walker, 2000, The Journal of pharmacology and experimental therapeutics.

Acetaminophen-induced hepatotoxicity in mice lacking inducible nitric oxide synthase activity.

N. Pumford, A. Warbritton, J. Hinson, 2001, Nitric oxide : biology and chemistry.

Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity.

S. Abdel‐Rahman, A. Milesi-Hallé, L. James, 2011, Chemico-biological interactions.

Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite.

D. Doerge, J. Hinson, P. Mayeux, 2010, Biochemical pharmacology.

Acetaminophen Toxicity in Mice Lacking NADPH Oxidase Activity: Role of Peroxynitrite Formation and Mitochondrial Oxidant Stress

H. Jaeschke, L. James, J. Hinson, 2003, Free radical research.

High-performance liquid chromatographic assay for acetaminophen and phenacetin in the presence of their metabolites in biological fluids.

K. Pang, A. Taburet, J. Hinson, 1979, Journal of chromatography.

NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia.

H. Jaeschke, A. Farhood, J. Hinson, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Proinsulin Atypical Maturation and Disposal Induces Extensive Defects in Mouse Ins2+/Akita β-Cells

K. Osei, Wei-Yu Tang, J. Hinson, 2012, PloS one.

Evaluation of propanil and its N-oxidized derivatives for genotoxicity in the Salmonella typhimurium reversion, Chinese hamster ovary/hypoxanthine guanine phosphoribosyl transferase, and rat hepatocyte/DNA repair assays

J. Shaddock, D. Casciano, D. McMillan, 1988 .

Microsoft Word-66827354-file00

T. Davern, P. Simpson, E. Capparelli, 2009 .

Acetaminophen-Induced Hepatotoxicity in Mice Occurs with Inhibition of Activity and Nitration of Mitochondrial Manganese Superoxide Dismutase

L. MacMillan-Crow, L. James, J. Hinson, 2011, Journal of Pharmacology and Experimental Therapeutics.

Mechanisms of acetaminophen oxidation to N-acetyl-P-benzoquinone imine by horseradish peroxidase and cytochrome P-450.

J. Hinson, D. Potter, 1987, The Journal of biological chemistry.

Reactive nitrogen species in acetaminophen-induced mitochondrial damage and toxicity in mouse hepatocytes.

L. MacMillan-Crow, J. Hinson, Angela S. Burke, 2010, Chemical research in toxicology.

Phase II enzymes and bioactivation.

J. Hinson, J A Hinson, P G Forkert, 1995, Canadian journal of physiology and pharmacology.

Studies on the activation of p-18O-phenacetin to a reactive metabolite in hamsters

S. Nelson, J. Hinson, J. Gillette, 1978 .

Chlorotyrosine protein adducts are reliable biomarkers of neutrophil-induced cytotoxicity in vivo

H. Jaeschke, J. Hinson, J. Gujral, 2004, Comparative hepatology.

Reactions of N-acetyl-p-benzoquinone imine with reduced glutathione, acetaminophen, and NADPH.

J. Hinson, D. Potter, 1986, Molecular pharmacology.

New insights into the mechanisms of acetaminophen toxicity

L. MacMillan-Crow, L. James, J. Hinson, 2010 .

Glossary and tutorial of xenobiotic metabolism terms used during small molecule drug discovery and development (IUPAC Technical Report)

N. Bodor, S. Wrighton, H. Masumoto, 2021, Pure and Applied Chemistry.

Acetaminophen-induced hepatotoxicity.

L. James, J. Hinson, P. Mayeux, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Fast atom bombardment mass spectrometry and fast atom bombardment mass spectrometry/mass spectrometry of three glutathione conjugates of acetaminophen.

J. Lay, J. Hinson, D. Potter, 1987, Biomedical & environmental mass spectrometry.

Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

William M. Lee, T. Davern, P. Simpson, 2009, Drug Metabolism and Disposition.