M. Ledwidge

K. McDonald, M. Ledwidge, B. Travers, 2003, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

FKBPL is associated with metabolic parameters and is a novel determinant of cardiovascular disease

A. Keech, A. Jenkins, A. Januszewski, 2020, Scientific Reports.

Diagnosis of heart failure with preserved ejection fraction: improved accuracy with the use of markers of collagen turnover

S. Donnelly, C. O’loughlin, K. McDonald, 2009, European journal of heart failure.

Aspirin Use in Heart Failure: Is Low Dose Therapy Associated with Mortality and Morbidity Benefits in a Large Community Population? Bermingham Et Al: Low-dose Aspirin and Mortality in Heart Failure

J. Gilmer, K. McDonald, M. Ledwidge, 2022 .

A systematic review of clinical prediction rules for the diagnosis of chronic heart failure

C. Watson, K. McDonald, M. Ledwidge, 2019, ESC heart failure.

Biomarker Testing and Pre-emptive Therapy in Preventing Heart Failure

C. Watson, K. McDonald, M. Ledwidge, 2015, Current Cardiovascular Risk Reports.

Serum Amyloid P-Component Prevents Cardiac Remodeling in Hypertensive Heart Disease

P. Collier, C. Watson, S. Horgan, 2015, Journal of Cardiovascular Translational Research.

STOP-HF Trial

P. McKie, M. Ledwidge, C. Watson, 2021, JACC. Basic to translational science.

Heart failure in sub‐Saharan Africa: review of the aetiology of heart failure and the role of point‐of‐care biomarker diagnostics

J. O’Donoghue, C. Watson, K. McDonald, 2015, Tropical medicine & international health : TM & IH.

Heart failure care in a hospital unit: a comparison of standard 3‐month and extended 6‐month programs

C. O’loughlin, K. McDonald, M. Ledwidge, 2005, European journal of heart failure.

Is multidisciplinary care of heart failure cost‐beneficial when combined with optimal medical care?

J. Cahill, K. McDonald, M. Ledwidge, 2003, European journal of heart failure.

Need and evolution of need for device therapy in a community heart failure population

C. O’loughlin, K. McDonald, M. Ledwidge, 2008, European journal of heart failure.

Life expectancy for community-based patients with heart failure from time of diagnosis.

M. Hensey, C. Watson, K. McDonald, 2015, International journal of cardiology.

426 A systematic review of clinical prediction rules to diagnose bacterial lower respiratory infection in children in primary care and their validation in a new cohort

C. Watson, M. Ledwidge, J. Gallagher, 2021, Abstracts.

Nondipping Nocturnal Blood Pressure Predicts Sleep Apnea in Patients With Hypertension.

W. McNicholas, S. Ryan, K. McDonald, 2019, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

Outpatient intravenous diuretic therapy; potential for marked reduction in hospitalisations for acute decompensated heart failure

C. O’loughlin, K. McDonald, M. Ledwidge, 2008, European journal of heart failure.

Community Direct Access Service for Early Detection and Treatment of Clinical Deterioration

C. O’loughlin, K. McDonald, M. Ledwidge, 2006 .

The biologic variability of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide in stable heart failure patients.

D. Phelan, C. O’loughlin, K. McDonald, 2007, Journal of cardiac failure.

Angiotensin Receptor Neprilysin Inhibitors in HFrEF: Is This the First Disease Modifying Therapy Drug Class Leading to a Substantial Reduction in Diuretic Need?

M. Barrett, K. McDonald, M. Ledwidge, 2021, International journal of heart failure.

Cardiac MRI e-prime predicts myocardial late gadolinium enhancement and diastolic dysfunction in hypertrophic cardiomyopathy.

J. Dodd, K. McDonald, P. Teekakirikul, 2022, European journal of radiology.

Natural history of markers of collagen turnover in patients with early diastolic dysfunction and impact of eplerenone.

D. Phelan, C. Watson, K. McDonald, 2009, Journal of the American College of Cardiology.

Heart failure management: multidisciplinary care has intrinsic benefit above the optimization of medical care.

J. Cahill, P. Quigley, K. McDonald, 2002, Journal of cardiac failure.

The Heart Failure Virtual Consultation — a powerful tool for the delivery of specialist care and the democratization of knowledge in the community

K. McDonald, M. Ledwidge, J. Gallagher, 2019, European journal of heart failure.

Comparison of longitudinal change in sST2 vs BNP to predict major adverse cardiovascular events in asymptomatic patients in the community

J. Januzzi, C. Watson, K. McDonald, 2020, Journal of cellular and molecular medicine.

Late cardiac effects of chemotherapy in breast cancer survivors treated with adjuvant doxorubicin: 10-year follow-up

J. Crown, C. Watson, G. Gullo, 2016, Breast Cancer Research and Treatment.

Natriuretic peptide-guided treatment for the prevention of cardiovascular events in patients without heart failure.

C. Ryan, C. Watson, K. McDonald, 2018, The Cochrane database of systematic reviews.

Multidisciplinary Care of Heart Failure: What Have We Learned and Where Can We Improve?

K. McDonald, M. Ledwidge, B. Travers, 2003, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

Heart failure management programs: can we afford to ignore the inpatient phase of care?

K. McDonald, M. Ledwidge, 2003, Journal of cardiac failure.

NT‐proBNP/BNP ratio for prognostication in European Caucasian patients enrolled in a heart failure prevention programme

C. Ryan, C. Watson, M. Barrett, 2021, ESC heart failure.

Mechanisms of aggregation inhibition by aspirin and nitrate‐aspirin prodrugs in human platelets

M. Radomski, M. Santos-Martinez, J. Gilmer, 2012, The Journal of pharmacy and pharmacology.

Changing to remote management of a community heart failure population during COVID-19 – Clinician and patient perspectives’

M. Barrett, K. McDonald, M. Ledwidge, 2020, IJC Heart & Vasculature.

Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults

A. Healy, J. Gilmer, M. Ledwidge, 2018, Acta Haematologica.

Extracellular matrix sub-types and mechanical stretch impact human cardiac fibroblast responses to transforming growth factor beta

D. Phelan, P. Collier, C. Watson, 2014, Connective tissue research.

TF-GCTS140011 248..256

D. Phelan, P. Collier, C. Watson, 2014 .

Public perceptions of pharmacogenomic services in Ireland - Are people with chronic disease more likely to want service availability than those without? A questionnaire study

C. Ryan, M. Ledwidge, J. M. Laughlin, 2022, Exploratory research in clinical and social pharmacy.

Diastolic Heart Failure Evidence of Increased Myocardial Collagen Turnover Linked to Diastolic Dysfunction Heart Failure

S. Donnelly, C. O’loughlin, K. McDonald, 2007 .

The prehospital patient pathway and experience of care with acute heart failure: a comparison of two health care systems

M. Cowie, J. Riley, K. McDonald, 2020, ESC heart failure.

Effects of environmental factors on the dehydration of diclofenac HEP dihydrate and theophylline monohydrate

O. Corrigan, M. Ledwidge, 1997 .

Nitric oxide-matrix metaloproteinase-9 interactions: biological and pharmacological significance--NO and MMP-9 interactions.

M. Radomski, J. Gilmer, M. Ledwidge, 2014, Biochimica et biophysica acta.

Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis

C. Watson, S. Horgan, K. McDonald, 2016, Journal of cardiovascular pharmacology and therapeutics.

Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype.

D. Phelan, P. Collier, A. McCann, 2014, Human molecular genetics.

MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure

T. Thum, C. Watson, Shashi K. Gupta, 2015, European journal of heart failure.

In vivo impact of prodrug isosorbide-5-nicotinate-2-aspirinate on lipids and prostaglandin D2: is this a new immediate-release therapeutic option for niacin?

D. Kerins, J. Gilmer, M. Ledwidge, 2012, Atherosclerosis.

The St Vincent's potentially inappropriate medicines study: development of a disease‐specific consensus list and its evaluation in ambulatory heart failure care

K. McDonald, M. Ledwidge, J. Gallagher, 2014, European journal of heart failure.

Importance of risk factor management in diabetic patients and reduction in Stage B heart failure.

J. Griffin, J. O’ Connell, C. Watson, 2015, QJM : monthly journal of the Association of Physicians.

Attenuation of Monocyte Chemotaxis—A Novel Anti-inflammatory Mechanism of Action for the Cardio-protective Hormone B-Type Natriuretic Peptide

P. Collier, C. Watson, K. McDonald, 2013, Journal of Cardiovascular Translational Research.

Physicochemical characterization of diclofenac N-(2-hydroxyethyl)pyrrolidine: anhydrate and dihydrate crystalline forms.

O. Corrigan, M. Ledwidge, S. Draper, 1996, Journal of pharmaceutical sciences.

Cost‐effectiveness of natriuretic peptide‐based screening and collaborative care: a report from the STOP‐HF (St Vincent's Screening TO Prevent Heart Failure) study

L. Tilson, C. Watson, K. McDonald, 2015, European journal of heart failure.

Can individualized weight monitoring using the HeartPhone algorithm improve sensitivity for clinical deterioration of heart failure?

K. McDonald, Mark T Ledwidge, Rory O'Hanlon, 2013, European journal of heart failure.

Screening to prevent heart failure (STOP‐HF): expanding the focus beyond asymptomatic left ventricular systolic dysfunction

K. McDonald, M. Ledwidge, G. Murtagh, 2012, European journal of heart failure.

Proteomic Analysis of Coronary Sinus Serum Reveals Leucine-Rich &agr;2-Glycoprotein as a Novel Biomarker of Ventricular Dysfunction and Heart Failure

M. Dunn, D. Phelan, P. Collier, 2011, Circulation. Heart failure.

Fluid restriction in the management of decompensated heart failure: no impact on time to clinical stability.

C. O’loughlin, K. McDonald, M. Ledwidge, 2007, Journal of cardiac failure.

Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial.

P. Ponikowski, P. Poole‐Wilson, S. Anker, 2007, Journal of the American College of Cardiology.

Clinical deterioration in established heart failure: What is the value of BNP and weight gain in aiding diagnosis?

C. O’loughlin, K. McDonald, M. Ledwidge, 2005, European journal of heart failure.

Pharmacogenetic interventions to improve outcomes in patients with multimorbidity or prescribed polypharmacy: a systematic review

C. Ryan, M. Ledwidge, J. Gallagher, 2022, The Pharmacogenomics Journal.

Targeted DNA Methylation Profiling of Human Cardiac Tissue Reveals Novel Epigenetic Traits and Gene Deregulation Across Different Heart Failure Patient Subtypes

D. Phelan, P. Collier, W. Gallagher, 2019, Circulation. Heart failure.

Multiple neurohumoral modulating agents in systolic dysfunction heart failure: are we lowering blood pressure too much?

C. O’loughlin, K. McDonald, G. Mak, 2008, Journal of cardiac failure.

Improvement but no cure of left ventricular systolic dysfunction in treated heart failure patients

C. O’loughlin, K. McDonald, M. Ledwidge, 2007, European journal of heart failure.

A Central Role for Monocyte–Platelet Interactions in Heart Failure

C. Watson, J. Gilmer, M. Ledwidge, 2016, Journal of cardiovascular pharmacology and therapeutics.

Prospective analysis of LDL-C goal achievement and self-reported medication adherence among statin users in primary care.

J. Hayden, K. McDonald, M. Ledwidge, 2011, Clinical therapeutics.

Are beta2‐agonists responsible for increased mortality in heart failure?

K. McDonald, M. Ledwidge, M. Bermingham, 2011, European journal of heart failure.

Differential inhibition of tumour cell‐induced platelet aggregation by the nicotinate aspirin prodrug (ST0702) and aspirin

M. Radomski, M. Santos-Martinez, J. Gilmer, 2012, British journal of pharmacology.

Elimination of early rehospitalization in a randomized, controlled trial of multidisciplinary care in a high‐risk, elderly heart failure population: the potential contributions of specialist care, clinical stability and optimal angiotensin‐converting enzyme inhibitor dose at discharge

J. Cahill, K. McDonald, M. Ledwidge, 2001, European journal of heart failure.

Developing a disease management program for the improvement of heart failure outcomes: the do’s and the don’ts

C. Watson, K. McDonald, M. Ledwidge, 2019, Expert review of cardiovascular therapy.

Profiling B-type natriuretic peptide in a stable heart failure population: a valuable adjunct to care

C. O’loughlin, K. McDonald, A. Jan, 2011, Irish journal of medical science.

Can we reduce preventable heart failure readmissions in patients enrolled in a Disease Management Programme?

D. Phelan, C. O’loughlin, K. McDonald, 2009, Irish journal of medical science.

Elevated BNP with normal systolic function in asymptomatic individuals at-risk for heart failure: a marker of diastolic dysfunction and clinical risk

J. Cahill, C. O’loughlin, K. McDonald, 2006, Irish journal of medical science.

Diabetes and complications of the heart in Sub-Saharan Africa: An urgent need for improved awareness, diagnostics and management.

C. Watson, K. McDonald, M. Ledwidge, 2018, Diabetes research and clinical practice.

Modest Elevation in BNP in Asymptomatic Hypertensive Patients Reflects Sub-Clinical Cardiac Remodeling, Inflammation and Extracellular Matrix Changes

D. Phelan, P. Collier, S. Donnelly, 2012, PloS one.

Heart Failure in Sub-Saharan Africa.

C. Watson, K. McDonald, M. Ledwidge, 2018, Cardiac failure review.

B-Type Natriuretic Peptide and Ventricular Dysfunction in the Prediction of Cardiovascular Events and Death in Hypertension

C. Watson, K. McDonald, M. Ledwidge, 2018, American journal of hypertension.

Causes and consequences of nonpersistence with heart failure medication.

C. O’loughlin, K. McDonald, M. Ledwidge, 2009, The American journal of cardiology.

Heart Failure Virtual Consultation: bridging the gap of heart failure care in the community ‐ A mixed‐methods evaluation

C. Watson, K. McDonald, M. Ledwidge, 2017, ESC heart failure.

Multiplexed measurement of candidate blood protein biomarkers of heart failure

K. McDonald, J. Baugh, C. Tonry, 2021, ESC heart failure.

Progression of preserved systolic function heart failure to systolic dysfunction -- a natural history study.

J. Cahill, K. McDonald, M. Ledwidge, 2006, International journal of cardiology.

225 Anaemia in a heart failure disease management program: iron deficiency or anaemia of chronic disease

K. McDonald, M. Ledwidge, Enda Ryan, 2003 .

Effect of Sacubitril/Valsartan vs Valsartan on Left Atrial Volume in Patients With Pre–Heart Failure With Preserved Ejection Fraction

J. Dodd, C. Watson, K. McDonald, 2023, JAMA cardiology.

FK506-Binding Protein like (FKBPL) Has an Important Role in Heart Failure with Preserved Ejection Fraction Pathogenesis with Potential Diagnostic Utility

M. Tesic, K. McDonald, L. McClements, 2023, Biomolecules.

Tetranectin, a potential novel diagnostic biomarker of heart failure, is expressed within the myocardium and associates with cardiac fibrosis

P. Collier, K. McDonald, J. Baugh, 2020, Scientific Reports.

Aetiology and severity of childhood pneumonia in primary care in Malawi: a cohort study

Sudipto Das, R. Drew, M. Ledwidge, 2021, BMJ Open.

Implementing Innovative Approaches to Healthcare in a Lower-Middle Income Country: Perspectives from Malawi

S. Taylor-Robinson, J. Gallagher, C. Watson, 2020, International journal of general medicine.

A Systematic Review of Clinical Prediction Rules to Predict Hospitalisation in Children with Lower Respiratory Infection in Primary Care and their Validation in a New Cohort

C. Watson, R. Drew, M. Ledwidge, 2021, EClinicalMedicine.

Decompensation of chronic heart failure associated with pregabalin in patients with neuropathic pain.

K. McDonald, M. Ledwidge, N. Murphy, 2007, Journal of cardiac failure.

Reassuring cardiac and non-cardiac outcomes for heart failure patients managed in a disease management programme during the COVID-19 pandemic

M. Barrett, K. McDonald, M. Ledwidge, 2021, IJC Heart & Vasculature.

Tetranectin, a potential novel diagnostic biomarker of heart failure, is expressed within the myocardium and associates with cardiac fibrosis

P. Collier, C. Watson, K. McDonald, 2020, Scientific Reports.

Biomarker profiling for risk of future heart failure (HFpEF) development

C. Watson, K. McDonald, M. Ledwidge, 2021, Journal of translational medicine.

A Machine Learning Approach for Chronic Heart Failure Diagnosis

D. Fotiadis, K. Naka, L. Michalis, 2021, Diagnostics.

Effects of surface active characteristics and solid state forms on the pH solubility profiles of drug–salt systems

O. Corrigan, Owen I. Corrigan, M. Ledwidge, 1998 .

Influence of Hospital Procedural Volume on Care Process and Mortality for Patients Undergoing Elective Surgery for Mitral Regurgitation

Sean M. O'Brien, Sean M O'Brien, Bartley P Griffith, 2007, Circulation.

ECSIT is a critical limiting factor for cardiac function

D. Stolz, D. Grieve, C. Watson, 2021, JCI insight.

Heart failure virtual consultation: caters for frailer, multimorbid and remote patients

M. Barrett, K. McDonald, M. Ledwidge, 2023, Open heart.

Influence of diabetes on natriuretic peptide thresholds in screening for Stage B heart failure

C. Watson, K. McDonald, D. O'Shea, 2016, Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.

Continuous positive airway pressure but not Liraglutide-mediated weight loss improves early cardiovascular disease in obstructive sleep apnea: Data from a randomized proof-of-concept study.

R. Gitau, S. Ryan, J. Dodd, 2023, medRxiv.

A systematic review of clinical prediction rules for the diagnosis of chronic heart failure

C. Watson, K. McDonald, M. Ledwidge, 2019, ESC heart failure.

Importance of risk factor management in diabetic patients and reduction in Stage B heart failure.

J. Griffin, J. Baugh, M. Ledwidge, 2015, QJM : monthly journal of the Association of Physicians.

Getting to the heart of cardiac remodeling; how collagen subtypes may contribute to phenotype.

D. Phelan, M. Tolan, J. Baugh, 2012, Journal of molecular and cellular cardiology.

Neurocardiogenic syncope: a model for SIDS

M. Ledwidge, T. Matthews, M. Ledwidge, 1998, Archives of disease in childhood.

Non-specific effects of Pneumococcal and Haemophilus vaccines in children aged 5 years and under: a systematic review

M. Ledwidge, Keith Geraghty, Darragh Rooney, 2023, BMJ Open.

Diastolic Heart Failure: Evidence of Increased Myocardial Collagen Turnover Linked to Diastolic Dysfunction

S. Donnelly, C. O’loughlin, K. McDonald, 2007, Circulation.

Respiratory syncytial virus-associated pneumonia in primary care in Malawi

M. Ledwidge, M. Chisale, Elena Koskinas, 2024, Journal of tropical pediatrics.

Alcohol consumption and heart failure: a dose-response meta-analysis.

M. Ledwidge, C. Reddin, Shuaiwei Zhou, 2024, The Cochrane database of systematic reviews.

Aspirin Use in Heart Failure: Is Low-Dose Therapy Associated With Mortality and Morbidity Benefits in a Large Community Population?

J. Gilmer, K. McDonald, M. Ledwidge, 2014, Circulation. Heart failure.

Heart Failure diagnosis based on deep learning techniques

D. Fotiadis, K. Naka, E. Tripoliti, 2021, 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

CPAP but Not GLP1-mediated Weight Loss Improves Early Cardiovascular Disease in Obstructive Sleep Apnea: A Randomized Proof-of-Concept Study.

M. Ledwidge, C. O’Donnell, Mark Traynor, 2023, Annals of the American Thoracic Society.