A. Mathis

发表

Preclinical Characterization and In Vivo Efficacy of GSK8853, a Small-Molecule Inhibitor of the Hepatitis C Virus NS4B Protein

R. Hamatake, J. Vamathevan, T. Shimada, 2015, Antimicrobial Agents and Chemotherapy.

A direct-acting antiviral drug abrogates viremia in Zika virus–infected rhesus macaques

Dane R. Schalk, A. Perelson, K. Best, 2020, Science Translational Medicine.

A novel class of fast‐acting antimalarial agents: Substituted 15‐membered azalides

F. Gamo, S. Alihodžić, Mirjana Bukvić, 2020, British journal of pharmacology.

Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents.

C. Moore, A. Mathis, J. Botyánszki, 2014, Journal of medicinal chemistry.

Rational design of potent non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Liping Wang, R. Nolte, E. Stewart, 2012, Journal of medicinal chemistry.

Discovery of a potent boronic acid derived inhibitor of the HCV RNA-dependent RNA polymerase.

R. Hamatake, Z. Hong, Shawn P. Williams, 2014, Journal of medicinal chemistry.

Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters

B. Gowen, Brady T. Hickerson, J. Westover, 2018, Antiviral Research.

Activity of Galidesivir in a Hamster Model of SARS-CoV-2

H. Bielefeldt-Ohmann, R. Bowen, Airn E. Hartwig, 2021, Viruses.

Accumulation and Intracellular Distribution of Antitrypanosomal Diamidine Compounds DB75 and DB820 in African Trypanosomes

D. Boykin, J. Hall, R. Tidwell, 2006, Antimicrobial Agents and Chemotherapy.

An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral

B. Gowen, D. Walling, A. Mathis, 2021, Antiviral Research.

Imidazo[1,2-a]pyridines That Directly Interact with Hepatitis C NS4B: Initial Preclinical Characterization.

D. J. Price, M. Thomson, R. Crosby, 2012, ACS medicinal chemistry letters.

Design of N-Benzoxaborole Benzofuran GSK8175—Optimization of Human Pharmacokinetics Inspired by Metabolites of a Failed Clinical HCV Inhibitor

D. J. Price, John Miller, Shawn P. Williams, 2019, Journal of medicinal chemistry.

Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanism.

Ryan Lauchli, A. Mathis, John F. Miller, 2014, Journal of medicinal chemistry.

Hepatitis C replication inhibitors that target the viral NS4B protein.

D. J. Price, R. Hamatake, Z. Hong, 2014, Journal of medicinal chemistry.

Antiparasitic compounds that target DNA.

W. Wilson, D. Boykin, J. Hall, 2008, Biochimie.

Dications that target the DNA minor groove: compound design and preparation, DNA interactions, cellular distribution and biological activity.

W. Wilson, Binh Nguyen, D. Boykin, 2005, Current medicinal chemistry. Anti-cancer agents.