W. Shang

发表

Comprehensive interactome analysis of the spike protein of swine acute diarrhea syndrome coronavirus

Zhènglì Shí, Gengfu Xiao, Yun Luo, 2021, Biosafety and Health.

A Subcellular Quantitative Proteomic Analysis of Herpes Simplex Virus Type 1-Infected HEK 293T Cells

Gengfu Xiao, Lei-ke Zhang, W. Shang, 2019, Molecules.

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

Jian He, Xiaming Jiang, Yuanyuan Sun, 2020, bioRxiv.

Novel and potent inhibitors targeting DHODH, a rate-limiting enzyme in de novo pyrimidine biosynthesis, are broad-spectrum antiviral against RNA viruses including newly emerged coronavirus SARS-CoV-2

Honglin Li, Gengfu Xiao, Zhenjiang Zhao, 2020, bioRxiv.

Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates

Xi Cheng, Lei-ke Zhang, Yan Wu, 2021, Acta Pharmacologica Sinica.

Visualizing lymphocytic choriomeningitis virus infection in cells and living mice

Gengfu Xiao, Lei-ke Zhang, Jingshi Wang, 2022, iScience.

In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2

Jian Li, Wenhao Dai, H. Su, 2022, Antiviral Research.

Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro

Gengfu Xiao, Zhìhóng Hú, Mingyue Xu, 2020, Virologica Sinica.

Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model

Gengfu Xiao, Lei-ke Zhang, Jingshan Shen, 2022, Signal Transduction and Targeted Therapy.

Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients

Kunqian Yu, Hualiang Jiang, Geng-fu Xiao, 2020, Acta Pharmacologica Sinica.

Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2

Yong Wang, Honglin Li, Lili Zhu, 2020, Protein & Cell.

Target-Based Virtual Screening and LC/MS-Guided Isolation Procedure for Identifying Phloroglucinol-Terpenoid Inhibitors of SARS-CoV-2

G. Gao, Hao Song, J. Qi, 2022, Journal of natural products.

Probing the Allosteric Inhibition Mechanism of a Spike Protein Using Molecular Dynamics Simulations and Active Compound Identifications

Fang Bai, Lin Wang, Lei-ke Zhang, 2021, Journal of medicinal chemistry.

Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein

Sheng Yao, Hong-Yang Wang, Fang Bai, 2021, Acta Pharmacologica Sinica.

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

Hualiang Jiang, Yechun Xu, Qiang Shao, 2021, Nature Communications.

Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

Z. Rao, Zhi-jie Liu, Haitao Yang, 2021, Nature Communications.

A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors

Ye-chun Xu, Lin Wang, Lei-ke Zhang, 2021, Acta Pharmacologica Sinica.

Novel inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives

S. Hasnain, Z. Rao, Zhi-jie Liu, 2021, bioRxiv.

Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension

Hao Li, Wei Liu, Gengfu Xiao, 2020, Cell Discovery.

High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against Arenaviruses and SARS-CoV-2

Gengfu Xiao, Lei-ke Zhang, Wei Liu, 2020, ACS infectious diseases.

Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

Hualiang Jiang, Shuyang Zhang, H. Xu, 2020, bioRxiv.

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

Kunqian Yu, Hualiang Jiang, Yechun Xu, 2020, bioRxiv.

Immunoglobulin fragment F(ab’)2 against RBD potently neutralizes SARS-CoV-2 in vitro

Gengfu Xiao, Xiaming Jiang, Yuanyuan Sun, 2020, bioRxiv.

RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates

Gengfu Xiao, Zili Wang, Cheng Peng, 2021, Cell discovery.

Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus

Gengfu Xiao, Lei-ke Zhang, Qingxing Wang, 2021, Viruses.

High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors

L. Guddat, Gengfu Xiao, Z. Rao, 2021, Protein & Cell.

Comprehensive Interactome Analysis Reveals that STT3B Is Required for N-Glycosylation of Lassa Virus Glycoprotein

Gengfu Xiao, Lei-ke Zhang, W. Shang, 2019, Journal of Virology.

Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection

Bo Wang, Gengfu Xiao, Zhìhóng Hú, 2019, Journal of Virology.

Drug Repurposing of Itraconazole and Estradiol Benzoate against COVID‐19 by Blocking SARS‐CoV‐2 Spike Protein‐Mediated Membrane Fusion

Gengfu Xiao, Shuwen Liu, Rong Zhang, 2021, Advanced therapeutics.

A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors

Hualiang Jiang, Fang Bai, Lin Wang, 2021, Acta pharmacologica Sinica.

Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2

Hualiang Jiang, Yechun Xu, Shuyang Zhang, 2021, Cell Research.

A Comparative Quantitative Proteomic Analysis of HCMV-Infected Cells Highlights pUL138 as a Multifunctional Protein

Gengfu Xiao, Yang Li, Lei-ke Zhang, 2020, Molecules.

Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir

Gengfu Xiao, Yan Zhang, H. Su, 2023, Nature communications.

A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir

Gengfu Xiao, Lei-ke Zhang, Jingshan Shen, 2023, Signal transduction and targeted therapy.

Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376

H. Xu, Lei-ke Zhang, W. Yin, 2022, Acta Pharmacologica Sinica.