Ralph W. H. Gottschalk

发表

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.

Andre Boorsma, J. Kleinjans, K. Brauers, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Prediagnostic plasma concentrations of organochlorines and risk of B-cell non-Hodgkin lymphoma in envirogenomarkers: a nested case-control study

M. Kogevinas, P. Vineis, R. Vermeulen, 2017, Environmental Health.

The role of glutathione in the regulation of nucleotide excision repair during oxidative stress.

R. Godschalk, F. V. van Schooten, S. Langie, 2007, Toxicology letters.

Alcohol consumption, alcohol dehydrogenase 1C (ADH1C) genotype, and risk of colorectal cancer in the Netherlands Cohort Study on diet and cancer.

R. Goldbohm, P. A. van den Brandt, M. van Engeland, 2011, Alcohol.

Bayesian Network Inference Enables Unbiased Phenotypic Anchoring of Transcriptomic Responses to Cigarette Smoke in Humans.

Diana M. Hendrickx, Diana M Hendrickx, J. Kleinjans, 2015, Chemical research in toxicology.

Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers.

J. Kleinjans, R. Godschalk, G. Haenen, 2007, Carcinogenesis.

Interindividual Variations in DNA Adduct Levels Assessed by Analysis of Multiple Genetic Polymorphisms in Smokers

J. Kleinjans, R. Godschalk, R. Vlietinck, 2006, Cancer Epidemiology Biomarkers & Prevention.

Potential role of cytochrome P450‐1B1 in the metabolic activation of 4‐aminobiphenyl in humans

J. Kleinjans, R. Godschalk, J. V. van Delft, 2009, Molecular carcinogenesis.

Whole Exome Sequencing Is the Preferred Strategy to Identify the Genetic Defect in Patients With a Probable or Possible Mitochondrial Cause

H. Smeets, R. Kamps, B. de Koning, 2018, Front. Genet..

Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs.

J. Kleinjans, R. Vlietinck, M. Gielen, 2006, Carcinogenesis.

Prevalence of at-risk genotypes for genotoxic effects decreases with age in a randomly selected population in Flanders: a cross sectional study

J. Kleinjans, V. Nelen, R. Godschalk, 2011, Environmental health : a global access science source.

Polyhydramnios and cerebellar atrophy: a prenatal presentation of mitochondrial encephalomyopathy caused by mutations in the FBXL4 gene

H. Smeets, F. Jansen, M. Haak, 2016, Clinical case reports.

Novel SLC25A32 mutation in a patient with a severe neuromuscular phenotype

H. Smeets, J. Bierau, S. Sallevelt, 2017, European Journal of Human Genetics.

Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis

M. Kogevinas, J. Vlaanderen, P. Vineis, 2017, BMC Genomics.

The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis.

M. Daemen, F. V. van Schooten, M. D. de Winther, 2007, Mutation research.

Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.

E. Wouters, A. Bast, L. Geraets, 2007, European journal of pharmacology.

Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet–gene interactions and promoter CpG island hypermethylation in colorectal cancer

R. Goldbohm, P. A. van den Brandt, M. van Engeland, 2010, Cancer Causes & Control.

Genetic Variants of Methyl Metabolizing Enzymes and Epigenetic Regulators: Associations with Promoter CpG Island Hypermethylation in Colorectal Cancer

Matty P Weijenberg, Piet A van den Brandt, R. Goldbohm, 2009, Cancer Epidemiology, Biomarkers & Prevention.

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

André Boorsma, Anne S Kienhuis, Richard S Paules, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

Multiplex Genotyping as a Biomarker for Susceptibility to Carcinogenic Exposure in the FLEHS Biomonitoring Study

J. Kleinjans, N. V. van Larebeke, J. V. van Delft, 2008, Cancer Epidemiology Biomarkers & Prevention.

Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

J. Pennings, H. van Loveren, R. Vandebriel, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices.

C. Ioannides, J. V. van Delft, F. V. van Schooten, 2008, Mutagenesis.

Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation.

D. Hebels, J. V. van Delft, F. V. van Schooten, 2007, Carcinogenesis.

Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents.

J. Kleinjans, J. V. van Delft, E. Moonen, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

R. Stierum, C. Dejong, J. Kleinjans, 2009, Toxicology in vitro : an international journal published in association with BIBRA.

Mitochondrial DNA copy number in colorectal cancer: between tissue comparisons, clinicopathological characteristics and survival.

P. A. van den Brandt, A. Voets, H. Smeets, 2015, Carcinogenesis.

Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking

Marlon J. A. Jetten, M. Kogevinas, P. Vineis, 2016, Scientific Reports.

Transcriptome Analysis in Peripheral Blood of Humans Exposed to Environmental Carcinogens: A Promising New Biomarker in Environmental Health Studies

J. Kleinjans, V. Nelen, N. V. van Larebeke, 2008, Environmental health perspectives.

Genomic analysis suggests higher susceptibility of children to air pollution.

André Boorsma, Marie Pedersen, Micheline Kirsch-Volders, 2008, Carcinogenesis.

Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases

M. Kogevinas, P. Vineis, R. Vermeulen, 2017, Scientific Reports.

Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells.

J. Kleinjans, J. V. van Delft, T. D. de Kok, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

A pro-inflammatory genotype predisposes to Barrett's esophagus.

E. Kuipers, J. Kleinjans, P. Siersema, 2008, Carcinogenesis.

Toxicogenomic profiles in relation to maternal immunotoxic exposure and immune functionality in newborns.

H. Meltzer, H. van Loveren, J. Kleinjans, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

R. Stierum, C. Dejong, J. Kleinjans, 2009, Toxicological sciences : an official journal of the Society of Toxicology.