L. Chamberlain

发表

The intracellular dynamic of protein palmitoylation

J. Greaves, C. Salaun, L. Chamberlain, 2010, The Journal of cell biology.

Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels

F. Saleem, M. Shipston, P. Ruth, 2008, Proceedings of the National Academy of Sciences.

DHHC palmitoyl transferases: substrate interactions and (patho)physiology.

J. Greaves, L. Chamberlain, 2011, Trends in biochemical sciences.

The SNARE Proteins SNAP-25 and SNAP-23 Display Different Affinities for Lipid Rafts in PC12 Cells

G. Gould, L. Chamberlain, C. Salaün, 2005, Journal of Biological Chemistry.

Detergents as tools for the purification and classification of lipid rafts

L. Chamberlain, 2004, FEBS letters.

Differential palmitoylation regulates intracellular patterning of SNAP25

J. Greaves, L. Chamberlain, 2011, Journal of Cell Science.

The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain

J. Greaves, L. Chamberlain, Juliet A. Carmichael, 2011, Molecular biology of the cell.

Dual role of the cysteine-string domain in membrane binding and palmitoylation-dependent sorting of the molecular chaperone cysteine-string protein.

J. Greaves, L. Chamberlain, 2006, Molecular biology of the cell.

The neuropathic potential of anti-GM1 autoantibodies is regulated by the local glycolipid environment in mice.

Kazuro Furukawa, H. Willison, J. Pediani, 2009, The Journal of clinical investigation.

Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse model

J. Pratt, R. Brett, D. Thomson, 2018, Experimental Neurology.

Distinct effects of alpha-SNAP, 14-3-3 proteins, and calmodulin on priming and triggering of regulated exocytosis

R. Burgoyne, A. Morgan, L. Chamberlain, 1995, The Journal of cell biology.

Cysteine‐String Protein

R. Burgoyne, L. Chamberlain, 2000, Journal of neurochemistry.

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry

Terry K. Smith, J. Greaves, L. Chamberlain, 2017, Proceedings of the National Academy of Sciences.

Development of a novel high-throughput screen for the identification of new inhibitors of protein S-acylation

C. Salaun, L. Chamberlain, N. Tomkinson, 2022, bioRxiv.

A molecular toggle after exocytosis sequesters the presynaptic syntaxin1a molecules involved in prior vesicle fusion

Rory R. Duncan, Colin Rickman, Weiping Lu, 2014, Nature Communications.

S-acylation of the Insulin-Responsive Aminopeptidase (IRAP): Quantitative analysis and Identification of Modified Cysteines

L. Chamberlain, M. Werno, 2015, Scientific Reports.

The Vesicle- and Target-SNARE Proteins That Mediate Glut4 Vesicle Fusion Are Localized in Detergent-insoluble Lipid Rafts Present on Distinct Intracellular Membranes*

G. Gould, L. Chamberlain, 2002, The Journal of Biological Chemistry.

Regulatory effects of post-translational modifications on zDHHC S-acyltransferases

L. Chamberlain, Filip Zmuda, 2020, The Journal of Biological Chemistry.

Lemonidis, Kimon and Werno, Martin W. and Greaves, Jennifer and Diez Ardanuy, Cinta and Sanchez Perez, Maria C. and Salaun, Christine and Thomson, David M. and Chamberlain, Luke H. (2015) The zDHHC family

J. Greaves, L. Chamberlain, M. Werno, 2018 .

Substrate selectivity in the zDHHC family of S-acyltransferases.

J. Greaves, C. Salaun, L. Chamberlain, 2017, Biochemical Society transactions.

The zDHHC family of S-acyltransferases.

J. Greaves, D. Thomson, C. Salaun, 2015, Biochemical Society transactions.

The Molecular Chaperone Function of the Secretory Vesicle Cysteine String Proteins*

R. Burgoyne, L. Chamberlain, 1997, The Journal of Biological Chemistry.

This information is current as Rafts Regulates Ligand Binding Activity RIIa ( CD 32 a ) with Lipid γ Association of Fc

M. Glennie, S. Hart, I. Dransfield, 2009 .

Association of FcγRIIa (CD32a) with Lipid Rafts Regulates Ligand Binding Activity1

M. Glennie, S. Hart, I. Dransfield, 2009, The Journal of Immunology.

Lipid Rafts and the Regulation of Exocytosis

L. Chamberlain, C. Salaün, D. James, 2004, Traffic.

Lipid Rafts as Regulators of SNARE Activity and Exocytosis

L. Chamberlain, C. Salaün, 2007 .

Inhibition of isoprenoid biosynthesis causes insulin resistance in 3T3‐L1 adipocytes

L. Chamberlain, 2001, FEBS letters.

Identification of a Novel Sequence Motif Recognized by the Ankyrin Repeat Domain of zDHHC17/13 S-Acyltransferases

L. Chamberlain, K. Lemonidis, Maria C. Sanchez-Perez, 2015, The Journal of Biological Chemistry.

Palmitoylation and the trafficking of peripheral membrane proteins.

J. Greaves, L. Chamberlain, Oforiwa A. Gorleku, 2013, Biochemical Society transactions.

Endoplasmic Reticulum Localization of DHHC Palmitoyltransferases Mediated by Lysine-based Sorting Signals*

G. R. Prescott, J. Greaves, L. Chamberlain, 2011, The Journal of Biological Chemistry.

S-acylation by the DHHC protein family.

J. Greaves, L. Chamberlain, 2010, Biochemical Society transactions.

The hydrophobic cysteine-rich domain of SNAP25 couples with downstream residues to mediate membrane interactions and recognition by DHHC palmitoyl transferases.

G. R. Prescott, M. Fukata, Y. Fukata, 2009, Molecular biology of the cell.

Palmitoylation and Membrane Interactions of the Neuroprotective Chaperone Cysteine-string Protein*

M. Fukata, Y. Fukata, J. Greaves, 2008, Journal of Biological Chemistry.

Plasma membrane targeting of exocytic SNARE proteins.

J. Greaves, L. Chamberlain, C. Salaün, 2004, Biochimica et biophysica acta.

The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation

J. Greaves, C. Salaun, L. Chamberlain, 2020, The Journal of Biological Chemistry.

The Linker Domain of SNAP25 Acts as a Flexible Molecular Spacer to Ensure Efficient S-Acylation

J. Greaves, C. Salaun, L. Chamberlain, 2020, bioRxiv.

Regional and developmental brain expression patterns of SNAP25 splice variants

G. R. Prescott, L. Chamberlain, 2011, BMC Neuroscience.

Palmitoylation of the SNAP25 Protein Family

J. Greaves, C. Salaun, L. Chamberlain, 2010, The Journal of Biological Chemistry.

Lipid Raft Association of SNARE Proteins Regulates Exocytosis in PC12 Cells*

G. Gould, L. Chamberlain, C. Salaün, 2005, Journal of Biological Chemistry.

Quantification of SNARE protein levels in 3T3-L1 adipocytes: implications for insulin-stimulated glucose transport.

V. H. Maier, G. Gould, G. Hickson, 2000, Biochemical and biophysical research communications.

Kouskou, Marianna and Thomson, David M. and Brett, Ros R. and Wheeler, Lee and Tate, Rothwelle J. and Pratt, Judith A. and Chamberlain, Luke H. (2018) Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse

J. Pratt, R. Brett, D. Thomson, 2019 .

Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy

J. Greaves, K. Faulds, D. Graham, 2018, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

Cysteine‐string proteins regulate exocytosis of insulin independent from transmembrane ion fluxes

C. Wollheim, R. Burgoyne, W. Kelley, 1998, FEBS letters.

Obesogenic and Diabetogenic Effects of High-Calorie Nutrition Require Adipocyte BK Channels

M. Shipston, P. Ruth, S. Offermanns, 2016, Diabetes.

A cluster of palmitoylated cysteines are essential for aggregation of cysteine-string protein mutants that cause neuronal ceroid lipofuscinosis

J. Greaves, L. Chamberlain, N. Tomkinson, 2017, Scientific Reports.

The cysteine-string domain of the secretory vesicle cysteine-string protein is required for membrane targeting.

R. Burgoyne, L. Chamberlain, 1998, The Biochemical journal.

Cysteine string protein functions directly in regulated exocytosis.

R. Burgoyne, L. Chamberlain, 1998, Molecular biology of the cell.

Identification of a Novel Cysteine String Protein Variant and Expression of Cysteine String Proteins in Non-neuronal Cells (*)

R. Burgoyne, L. Chamberlain, 1996, The Journal of Biological Chemistry.

SNAPs and SNAREs in exocytosis in chromaffin cells.

R. J. Barnard, R. Burgoyne, A. Morgan, 1996, Biochemical Society transactions.

The Golgi S-acylation machinery comprises zDHHC enzymes with major differences in substrate affinity and S-acylation activity

Christopher Grefen, L. Chamberlain, Oforiwa A. Gorleku, 2014, Molecular biology of the cell.

Palmitoylation-induced Aggregation of Cysteine-string Protein Mutants That Cause Neuronal Ceroid Lipofuscinosis*

Christopher Grefen, Carlos Cruchaga, Christopher Grefen, 2012, The Journal of Biological Chemistry.

The physiology of protein S-acylation.

M. Shipston, L. Chamberlain, 2015, Physiological reviews.

Neomycin Prevents the Wortmannin Inhibition of Insulin-stimulated Glut4 Translocation and Glucose Transport in 3T3-L1 Adipocytes*

J. Connell, L. Chamberlain, C. Salaün, 2004, Journal of Biological Chemistry.

Palmitoylation of the synaptic vesicle fusion machinery

G. R. Prescott, J. Greaves, L. Chamberlain, 2009, Journal of neurochemistry.

LIF-dependent survival of embryonic stem cells is regulated by a novel palmitoylated Gab1 signalling protein

A. Joshi, Austin G Smith, T. Burdon, 2018, Journal of Cell Science.

Identification of key features required for efficient S-acylation and plasma membrane targeting of sprouty-2

C. Salaun, L. Chamberlain, C. Locatelli, 2020, Journal of Cell Science.

New links between S‐acylation and cancer

J. Greaves, L. Chamberlain, 2014, The Journal of pathology.

Fam49/CYRI interacts with Rac1 and locally suppresses protrusions

Matthew P. Neilson, K. Anderson, P. Thomason, 2018, Nature Cell Biology.

Peptide array-based screening reveals a large number of proteins interacting with the ankyrin-repeat domain of the zDHHC17 S-acyltransferase

G. Baillie, L. Chamberlain, K. Lemonidis, 2017, The Journal of Biological Chemistry.

SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis

G. Gould, R. Burgoyne, L. Chamberlain, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Jcb: Mini-review Introduction

J. Greaves, L. Chamberlain, 2022 .

Regulation of SNAP-25 trafficking and function by palmitoylation.

G. R. Prescott, J. Greaves, L. Chamberlain, 2010, Biochemical Society transactions.

Phosphorylation of Cysteine String Protein by Protein Kinase A

R. Burgoyne, A. Morgan, L. Chamberlain, 2001, The Journal of Biological Chemistry.

The synaptic vesicle protein, cysteine-string protein, is associated with the plasma membrane in 3T3-L1 adipocytes and interacts with syntaxin 4.

S. Kane, V. H. Maier, G. Gould, 2001, Journal of cell science.

Mutational analysis of cysteine-string protein function in insulin exocytosis.

R. Burgoyne, W. Kelley, L. Chamberlain, 1999, Journal of cell science.

Activation of the ATPase activity of heat-shock proteins Hsc70/Hsp70 by cysteine-string protein.

R. Burgoyne, L. Chamberlain, L H Chamberlain, 1997, The Biochemical journal.

t-SNARE Protein Conformations Patterned by the Lipid Microenvironment*

O. Mandula, R. Duncan, S. Rizzoli, 2010, The Journal of Biological Chemistry.

The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells

J. Greaves, T. Bushell, Louise Ritchie, 2017, Molecular and Cellular Neuroscience.

The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif

G. Banting, L. Chamberlain, Oforiwa A. Gorleku, 2013, Biology Open.

Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons

N. Gay, C. Bryant, John A. Wright, 2018, Neuropharmacology.

Evidence for a Role of the Exocyst in Insulin-stimulated Glut4 Trafficking in 3T3-L1 Adipocytes*

S. Kane, G. Gould, M. Clarke, 2005, Journal of Biological Chemistry.

Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.

Wanjin Hong, Nicholas J Morris, W. Hong, 2003, Molecular biology of the cell.

Fam49/CYRI interacts with Rac1 and locally suppresses protrusions

Matthew P. Neilson, K. Anderson, P. Thomason, 2018, Nature Cell Biology.

The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

G. R. Prescott, J. Greaves, L. Chamberlain, 2009, Molecular membrane biology.

S-acylation regulates the trafficking and stability of the unconventional Q-SNARE STX19

M. Collins, J. Greaves, A. Peden, 2018, Journal of Cell Science.

Munc18-1 prevents the formation of ectopic SNARE complexes in living cells

Colin Rickman, Rory R Duncan, R. Duncan, 2007, Journal of Cell Science.

CYRI (FAM49) proteins are local inhibitors of Scar/WAVE induced lamellipodia that bind directly to active Rac1

Matthew P. Neilson, K. Anderson, P. Thomason, 2017, bioRxiv.

CYRI ( FAM 49 ) is a Rac 1 interacting local inhibitor of actin-based protrusion

Jamie, Matthew P. Neilson, P. Thomason, 2019 .

GEMS–RCPSG: ‘Is Academic Medicine for Me?’ National Conference 2011, 19 November 2011

H. Branigan, D. Webb, H. Grabsch, 2012 .

Regulatory effects of protein S-acylation on insulin secretion and insulin action

M. Shipston, G. Gould, L. Chamberlain, 2021, Open Biology.

Accessory proteins of the zDHHC family of S-acylation enzymes

C. Salaun, L. Chamberlain, Filip Zmuda, 2020, Journal of Cell Science.

Salaun, Christine and Ritchie, Louise and Greaves, Jennifer and Bushell,

J. Greaves, T. Bushell, Louise Ritchie, 2018 .

Evolving views on protein palmitoylation (Comment on DOI 10.1002/bies.201300076)

L. Chamberlain, 2013, Bioessays.

Cysteine String Proteins Are Associated with Chromaffin Granules*

R. Burgoyne, L. Chamberlain, J. Henry, 1996, The Journal of Biological Chemistry.

Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons. Short title: TLR3 activation impairs neuronal function

C. Bryant, John A. Wright, M. Zagnoni, 2018 .

Palmitoylation-dependent protein sorting

J. Greaves, L. Chamberlain, 2022 .

The endoplasmic reticulum–localized enzyme zDHHC6 mediates S-acylation of short transmembrane constructs from multiple type I and II membrane proteins

C. Salaun, L. Chamberlain, N. Tomkinson, 2023, The Journal of biological chemistry.