De-an Wang

发表

Palmitoylated Cysteine 192 Is Required for RhoB Tumor-suppressive and Apoptotic Activities*

S. Sebti, Said M Sebti, De-an Wang, 2005, Journal of Biological Chemistry.

Inhibition of Ca2+ signalling by the sphingosine 1-phosphate receptor S1P1

K. Jakobs, G. Tigyi, De-an Wang, 2003 .

Structure-activity studies on a library of potent calix[4]arene-based PDGF antagonists that inhibit PDGF-stimulated PDGFR tyrosine phosphorylation.

S. Sebti, A. Hamilton, Huchen Zhou, 2006, Organic & biomolecular chemistry.

Optimal Lysophosphatidic Acid-induced DNA Synthesis and Cell Migration but Not Survival Require Intact Autophosphorylation Sites of the Epidermal Growth Factor Receptor*

T. Patel, L. Johnson, H. Poppleton, 2004, Journal of Biological Chemistry.

Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate.

W. Siess, G. Tigyi, De-an Wang, 2003, Cellular signalling.

Injury-elicited differential transcriptional regulation of phospholipid growth factor receptors in the cornea.

G. Tigyi, D. Brindley, M. Watsky, 2002, American journal of physiology. Cell physiology.

Identification of the Hydrophobic Ligand Binding Pocket

Y. Fujiwara, A. Parrill, K. Liliom, 2007 .

Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors

D. Coppola, S. Sebti, A. Hamilton, 2004, Oncogene.

Pharmacological Characterization of Phospholipid Growth‐Factor Receptors

Duane D. Miller, D. Baker, A. Parrill, 2000, Annals of the New York Academy of Sciences.

LPA protects intestinal epithelial cells from apoptosis by inhibiting the mitochondrial pathway.

E. Gosmanova, L. Johnson, G. Tigyi, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Lysophosphatidic acid protects and rescues intestinal epithelial cells from radiation- and chemotherapy-induced apoptosis.

L. Johnson, G. Tigyi, De-an Wang, 2002, Gastroenterology.

Molecular basis for lysophosphatidic acid receptor antagonist selectivity.

D. Baker, A. Parrill, G. Tigyi, 2002, Biochimica et biophysica acta.

A Single Amino Acid Determines Lysophospholipid Specificity of the S1P1 (EDG1) and LPA1 (EDG2) Phospholipid Growth Factor Receptors*

A. Parrill, K. Liliom, Z. Lorincz, 2001, The Journal of Biological Chemistry.

Geranylgeranyltransferase I Inhibitors Target RalB To Inhibit Anchorage-Dependent Growth and Induce Apoptosis and RalA To Inhibit Anchorage-Independent Growth

C. Der, S. Sebti, A. Hamilton, 2007, Molecular and Cellular Biology.

Identification of the Hydrophobic Ligand Binding Pocket of the S1P1 Receptor*

Y. Fujiwara, A. Parrill, K. Liliom, 2007, Journal of Biological Chemistry.

Phospholipid Growth Factors and Corneal Wound Healing

G. Tigyi, M. Griffith, M. Watsky, 2000, Annals of the New York Academy of Sciences.

Identification of Edg1 Receptor Residues That Recognize Sphingosine 1-Phosphate*

S. Spiegel, D. Baker, A. Parrill, 2000, The Journal of Biological Chemistry.

Lipid phosphate phosphatase-1 and Ca2+ control lysophosphatidate signaling through EDG-2 receptors.

L. Berthiaume, G. Tigyi, James Xu, 2000, The Journal of biological chemistry.

Inhibition of Ca(2+) signalling by the sphingosine 1-phosphate receptor S1P(1).

K. Jakobs, G. Tigyi, De-an Wang, 2003, Cellular signalling.

Structural Features of EDG1 Receptor‐Ligand Complexes Revealed by Computational Modeling and Mutagenesis

S. Spiegel, D. Baker, A. Parrill, 2000, Annals of the New York Academy of Sciences.

Lysophosphatidic acid as a regulator of endothelial/leukocyte interaction.

J. Berliner, N. Leitinger, H. Lee, 1999, Laboratory investigation; a journal of technical methods and pathology.

Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter

S. Sebti, S. Chellappan, A. Hamilton, 2007, Oncogene.