Damian J. Houde

发表

Rapid characterization of IgG 1 conformation and conformational dynamics by hydrogen / deuterium exchange mass spectrometry

S. Berkowitz, J. Arndt, Damian J. Houde, 2009 .

Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding*

Damian Houde, John R Engen, J. R. Engen, 2010, Molecular & Cellular Proteomics.

Influence of glycan modification on IgG1 biochemical and biophysical properties

I. Kaltashov, Tyler Carlage, Damian J. Houde, 2018, Journal of pharmaceutical and biomedical analysis.

Engineering Aglycosylated IgG Variants with Wild-Type or Improved Binding Affinity to Human Fc Gamma RIIA and Fc Gamma RIIIAs.

Stephen L. Sazinsky, K. Wittrup, Huawei Qiu, 2017, Journal of molecular biology.

A comparison of three techniques for quantitative carbohydrate analysis used in characterization of therapeutic antibodies.

Yelena Lyubarskaya, Rohin Mhatre, Damian Houde, 2006, Carbohydrate research.

Scattering techniques for the characterization of biopharmaceuticals

L. Makowski, S. Berkowitz, Damian J. Houde, 2020, Biophysical Characterization of Proteins in Developing Biopharmaceuticals.

Scattering techniques for the characterization of biopharmaceuticals

L. Makowski, S. Berkowitz, Damian J. Houde, 2020, Biophysical Characterization of Proteins in Developing Biopharmaceuticals.

Investigating the conformation and conformational dynamics of protein biopharmaceuticals with hydrogen/deuterium exchange mass spectrometry

Damian J. Houde, D. Houde, 2010 .

The Role of Hydrogen Exchange Mass Spectrometry in Assessing the Consistency and Comparability of the Higher‐Order Structure of Protein Biopharmaceuticals

S. Berkowitz, Damian J. Houde, D. Houde, 2016 .

Investigating the Role of Artemin Glycosylation

K. Rand, Christian Code, J. Arndt, 2016, Pharmaceutical Research.

Conformation and dynamics of biopharmaceuticals: Transition of mass spectrometry-based tools from academe to industry

S. Berkowitz, I. Kaltashov, Damian J. Houde, 2010, Journal of the American Society for Mass Spectrometry.

Technical Decision-Making with Higher Order Structure Data: Detecting Reversible Concentration-Dependent Self-Association in a Monoclonal Antibody and a Preliminary Investigation to Eliminate It.

Damian J. Houde, G. Bou-Assaf, A. Weiskopf, 2015, Journal of pharmaceutical sciences.

The utility of hydrogen/deuterium exchange mass spectrometry in biopharmaceutical comparability studies.

S. Berkowitz, Damian J. Houde, J. Engen, 2011, Journal of pharmaceutical sciences.

Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry.

S. Berkowitz, J. Arndt, Damian J. Houde, 2009, Analytical chemistry.

Fine details of IGF-1R activation, inhibition, and asymmetry determined by associated hydrogen /deuterium-exchange and peptide mass mapping.

S. Demarest, Damian J. Houde, D. Houde, 2011, Structure.

Rapid Conformational Analysis of Protein Drugs in Formulation by Hydrogen/Deuterium Exchange Mass Spectrometry.

M. van de Weert, Damian J. Houde, G. Bou-Assaf, 2016, Journal of pharmaceutical sciences.

Conformational analysis of recombinant monoclonal antibodies with hydrogen/deuterium exchange mass spectrometry.

Damian J. Houde, J. Engen, D. Houde, 2013, Methods in molecular biology.

Abstract 2150: engEx: A novel exosome engineering platform enabling targeted transfer of pharmacological molecules

S. Sathyanarayanan, A. Boutin, S. Jang, 2019, Experimental and Molecular Therapeutics.

Abstract 944: exoSTING: An engineered exosome therapeutic that selectively delivers STING agonist to the tumor resident antigen-presenting cells resulting in improved tumor antigen-specific adaptive immune response

R. Moniz, S. Estes, S. Sathyanarayanan, 2019, Immunology.

Determination of protein oxidation by mass spectrometry and method transfer to quality control.

Y. Lyubarskaya, R. Mhatre, Damian J. Houde, 2006, Journal of chromatography. A.

Conformational comparability of factor IX-Fc fusion protein, factor IX, and purified Fc fragment in the absence and presence of calcium.

S. Berkowitz, DAMIAN HOUDE, STEVEN A. BERKOWITZ, 2012, Journal of pharmaceutical sciences.

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Jie Zheng, Albert J R Heck, Christoph Borchers, 2019, Nature Methods.

Biopharmaceutical industry's biophysical toolbox

Damian Houde, Steven A. Berkowitz, S. Berkowitz, 2020, Biophysical Characterization of Proteins in Developing Biopharmaceuticals.

A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties

R. Moniz, S. Estes, S. Sathyanarayanan, 2021, Molecular therapy : the journal of the American Society of Gene Therapy.

Biophysical characterization and its role in the biopharmaceutical industry

Damian Houde, Steven A. Berkowitz, S. Berkowitz, 2020, Biophysical Characterization of Proteins in Developing Biopharmaceuticals.

Size-exclusion chromatography (SEC) in biopharmaceutical process development

S. Berkowitz, Damian J. Houde, D. Houde, 2020, Biophysical Characterization of Proteins in Developing Biopharmaceuticals.

Size-Exclusion Chromatograph (SEC) in Biopharmaceutical Process Development

S. Berkowitz, Damian J. Houde, D. Houde, 2015 .

Characterization of a PEGylated protein therapeutic by ion exchange chromatography with on-line detection by native ESI MS and MS/MS.

Damian Houde, Zoran Sosic, I. Kaltashov, 2017, The Analyst.

Technical Decision Making With Higher Order Structure Data: Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry.

Guodong Chen, William F Weiss, Damian Houde, 2016, Journal of pharmaceutical sciences.

Investigating monoclonal antibody aggregation using a combination of H/DX-MS and other biophysical measurements.

L. Makowski, S. Berkowitz, Roxana E. Iacob, 2013, Journal of pharmaceutical sciences.

The complexity of protein structure and the challenges it poses in developing biopharmaceuticals

S. Berkowitz, Damian J. Houde, D. Houde, 2020, Biophysical Characterization of Proteins in Developing Biopharmaceuticals.

Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.

Rohin Mhatre, Damian Houde, Igor A Kaltashov, 2008, Analytical chemistry.

Analysis of recombinant monoclonal antibody isoforms by electrospray ionization mass spectrometry as a strategy for streamlining characterization of recombinant monoclonal antibody charge heterogeneity.

Yelena Lyubarskaya, Rohin Mhatre, Damian Houde, 2006, Analytical biochemistry.

Utility of Solution X-Ray Scattering for the Development of Antibody Biopharmaceuticals.

Lee Makowski, Damian Houde, L. Makowski, 2016, Journal of pharmaceutical sciences.