S. Sugita

发表

Differential effects of 4-aminopyridine, serotonin, and phorbol esters on facilitation of sensorimotor connections in Aplysia.

D. A. Baxter, J. Byrne, D A Baxter, 1997, Journal of neurophysiology.

Diverse exocytic pathways for mast cell mediators.

S. Sugita, Hao Xu, Na-Ryum Bin, 2018, Biochemical Society transactions.

Distinct Ca(2+)-dependent properties of the first and second C2-domains of synaptotagmin I.

T. Südhof, Y. Hata, S. Sugita, 1996, The Journal of biological chemistry.

A conformational switch in syntaxin during exocytosis: role of munc18

T. Südhof, I. Dulubova, J. Rizo, 1999, The EMBO journal.

Munc18b Is a Major Mediator of Insulin Exocytosis in Rat Pancreatic β-Cells

H. Kasai, M. Kauppi, V. Olkkonen, 2013, Diabetes.

Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells

D. Zhu, Seungmee Park, S. Sugita, 2013, Diabetologia.

Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis

T. Liang, C. Ostenson, S. Sugita, 2017, EBioMedicine.

RalA-Exocyst Interaction Mediates GTP-dependent Exocytosis*

S. Sugita, Li Wang, Gang Li, 2004, Journal of Biological Chemistry.

RalA and RalB Function as the Critical GTP Sensors for GTP-Dependent Exocytosis

Q. Wan, S. Sugita, S. Chiew, 2007, The Journal of Neuroscience.

Neuronal SNAP-23 scales hippocampal synaptic plasticity and memory

Zhong-Ping Feng, Hong-Shuo Sun, J. Pessin, 2022, bioRxiv.

Calcium-dependent Activator Protein for Secretion 1 (CAPS1) Binds to Syntaxin-1 in a Distinct Mode from Munc13-1*

Seungmee Park, S. Sugita, Lijun Li, 2013, The Journal of Biological Chemistry.

Propofol-induced Inhibition of Catecholamine Release Is Reversed by Maintaining Calcium Influx

Aiping Li, S. Sugita, R. Sandhu, 2016, Anesthesiology.

N-Terminal Insertion and C-Terminal Ankyrin-Like Repeats of α-Latrotoxin Are Critical for Ca2+-Dependent Exocytosis

Zhong-Ping Feng, S. Sugita, S. Chiew, 2005, The Journal of Neuroscience.

Neurexins are functional alpha-latrotoxin receptors.

T. Südhof, S. Sugita, M. Khvochtev, 1999, Neuron.

TNF Production in Activated RBL-2H3 Cells Requires Munc13-4

S. Sugita, Hao Xu, Pratikshya Adhikari, 2020, Inflammation.

Novel role of glial syntaxin‐1B in supporting neuronal survival

Seungmee Park, S. Sugita, Na-Ryum Bin, 2014, Journal of neurochemistry.

Specificity of Ca2+-dependent protein interactions mediated by the C2A domains of synaptotagmins.

T. Südhof, S. Sugita, 2000, Biochemistry.

A stoichiometric complex of neurexins and dystroglycan in brain

T. Südhof, K. Campbell, J. Satz, 2001, The Journal of cell biology.

α-Latrotoxin Receptor CIRL/Latrophilin 1 (CL1) Defines an Unusual Family of Ubiquitous G-protein-linked Receptors

T. Südhof, K. Ichtchenko, S. Sugita, 1998, The Journal of Biological Chemistry.

RalA GTPase Tethers Insulin Granules to L‐ and R‐Type Calcium Channels Through Binding α2δ‐1 Subunit

D. James, T. Liang, S. Chidambaram, 2013, Traffic.

Synaptotagmins form a hierarchy of exocytotic Ca2+ sensors with distinct Ca2+ affinities

T. Südhof, Y. Lao, S. Sugita, 2002, The EMBO journal.

Systemic Polyethylene Glycol Promotes Neurological Recovery and Tissue Sparing in Rats After Cervical Spinal Cord Injury

M. Fehlings, D. Baptiste, S. Sugita, 2009, Journal of neuropathology and experimental neurology.

Synaptogyrins Regulate Ca2+-dependent Exocytosis in PC12 Cells*

T. Südhof, R. Janz, S. Sugita, 1999, The Journal of Biological Chemistry.

Ca2+-dependent Activator Protein for Secretion 1 Is Critical for Constitutive and Regulated Exocytosis but Not for Loading of Transmitters into Dense Core Vesicles*

S. Sugita, H. Gaisano, S. Chiew, 2007, Journal of Biological Chemistry.

Regulation of PINK1 by NR2B‐containing NMDA receptors in ischemic neuronal injury

Q. Wan, Bao-song Liu, N. Chang, 2009, Journal of neurochemistry.

α-Latrotoxin and Its Receptors

A. Rohou, S. Sugita, Y. Ushkaryov, 2008 .

alpha-Latrotoxin and its receptors.

A. Rohou, S. Sugita, Y. Ushkaryov, 2008, Handbook of experimental pharmacology.

alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis.

T. Südhof, K. Ichtchenko, S. Sugita, 1998, The Journal of biological chemistry.

cAMP-independent effects of 8-(4-parachlorophenylthio)-cyclic AMP on spike duration and membrane currents in pleural sensory neurons of Aplysia.

D. A. Baxter, J. Byrne, S. Sugita, 1994, Journal of neurophysiology.

Sr2+ Binding to the Ca2+ Binding Site of the Synaptotagmin 1 C2B Domain Triggers Fast Exocytosis without Stimulating SNARE Interactions

T. Südhof, Christian Rosenmund, J. Rhee, 2003, Neuron.

Synaptotagmin VII as a Plasma Membrane Ca2+ Sensor in Exocytosis

T. Südhof, Xinran Liu, S. Butz, 2001, Neuron.

Distinct Ca-dependent Properties of the First and Second C-domains of Synaptotagmin I (*)

T. Südhof, Y. Hata, S. Sugita, 1996, The Journal of Biological Chemistry.

Ischemic stroke resulting from a transient or permanent blockade of cerebral blood flow causes neurodegeneration and neuronal death via a complex cascade of cell events

Q. Wan, Bao-song Liu, N. Chang, 2009 .

Crystal Structure of the Second LNS/LG Domain from Neurexin 1α

T. Südhof, G. Rudenko, L. Henry, 2006, Journal of Biological Chemistry.

Neurexins Are Functional α-Latrotoxin Receptors

T. Südhof, S. Sugita, M. Khvochtev, 1999, Neuron.

The Munc18-1 domain 3a loop is essential for neuroexocytosis but not for syntaxin-1A transport to the plasma membrane

Nancy T. Malintan, Jennifer L. Martin, Sally Martin, 2013, Journal of Cell Science.

A conformational switch in the Piccolo C2A domain regulated by alternative splicing

Josep Rizo, T. Südhof, S. Gerber, 2004, Nature Structural &Molecular Biology.

C2 Domains of Munc13-4 Are Crucial for Ca2+-Dependent Degranulation and Cytotoxicity in NK Cells

Hong-Shuo Sun, Ekaterina Turlova, P. van der Sluijs, 2018, The Journal of Immunology.

Transient Receptor Potential Melastatin 2 ( TRPM 2 ) Channel Plays a Role in Neonatal Hypoxic-Ischemic Brain Injury

Zhong-Ping Feng, Hong-Shuo Sun, Haitao Wang, 2016 .

The RIM/NIM Family of Neuronal C2 Domain Proteins

T. Südhof, Yun Wang, Yun Wang, 2000, The Journal of Biological Chemistry.

UNC-18 and Tomosyn Antagonistically Control Synaptic Vesicle Priming Downstream of UNC-13 in Caenorhabditis elegans

J. Rizo, M. Zhen, Shangbang Gao, 2017, The Journal of Neuroscience.

Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion

J. Rizo, B. Quade, C. Brautigam, 2017, eLife.

Conformational states of syntaxin-1 govern the necessity of N-peptide binding in exocytosis of PC12 cells and Caenorhabditis elegans

M. Zhen, M. Ikura, Matthew J. Smith, 2016, Molecular biology of the cell.

Continuous Monitoring via Tethered Electroencephalography of Spontaneous Recurrent Seizures in Mice

James H. Eubanks, Liang Zhang, J. Eubanks, 2017, Front. Behav. Neurosci..

Cholesterol synthesis inhibition promotes axonal regeneration in the injured central nervous system

A. Shabanzadeh, P. Monnier, P. Koeberle, 2021, Neurobiology of Disease.

α‐Latrotoxin action probed with recombinant toxin: receptors recruit α‐latrotoxin but do not transduce an exocytotic signal

T. Südhof, K. Ichtchenko, L. Simpson, 1998, The EMBO journal.

α-Latrotoxin Stimulates a Novel Pathway of Ca2+-Dependent Synaptic Exocytosis Independent of the Classical Synaptic Fusion Machinery

T. Südhof, Xinran Liu, F. Deák, 2009, The Journal of Neuroscience.

Involvement of protein kinase C in serotonin-induced spike broadening and synaptic facilitation in sensorimotor connections of Aplysia.

D. A. Baxter, J. Byrne, D A Baxter, 1992, Journal of neurophysiology.

NECABs: a family of neuronal Ca2+-binding proteins with an unusual domain structure and a restricted expression pattern

T. Südhof, A. Ho, S. Sugita, 2002, Neuroscience.

Munc18‐1 as a key regulator of neurosecretion

Nancy T. Malintan, B. Collins, F. Meunier, 2010, Journal of neurochemistry.

Extracellular phosphorylation drives the formation of neuronal circuitry

J. Cloutier, L. Attisano, R. Bremner, 2019, Nature Chemical Biology.

Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells

P. Hiesinger, S. Grinstein, V. Baert, 2012, The Journal of cell biology.

Open syntaxin overcomes exocytosis defects of diverse mutants in C. elegans

J. Rizo, M. Zhen, Shangbang Gao, 2020, Nature Communications.

Open syntaxin overcomes synaptic transmission defects in diverse C. elegans exocytosis mutants

J. Rizo, M. Zhen, Shangbang Gao, 2020, bioRxiv.

Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells.

B. Davletov, P. Monnier, S. Sugita, 2007, Molecular biology of the cell.

Munc 18-1 Is Critical for Plasma Membrane Localization of Syntaxin 1 but Not of SNAP-25 in PC 12 Cells

B. Davletov, P. Monnier, S. Sugita, 2008 .

Observations From a Mouse Model of Forebrain Voa1 Knockout: Focus on Hippocampal Structure and Function

P. Monnier, Liang Zhang, Y. Wada, 2019, Front. Cell. Neurosci..

Vacuolar H+-ATPase subunits Voa1 and Voa2 cooperatively regulate secretory vesicle acidification, transmitter uptake, and storage

Y. Wada, G. Sun-Wada, S. Sugita, 2011, Molecular biology of the cell.

Cholesterol-Dependent Kinase Activity Regulates Transmitter Release from Cerebellar Synapses

Alex J. Smith, M. Charlton, S. Sugita, 2010, The Journal of Neuroscience.

Neuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation

L. Zhang, Zhong-Ping Feng, Hong-Shuo Sun, 2023, iScience.

Abrogating Munc18-1-SNARE Complex Interaction Has Limited Impact on Exocytosis in PC12 Cells*

Nancy T. Malintan, B. Collins, F. Meunier, 2009, The Journal of Biological Chemistry.

Mechanisms of exocytosis

S. Sugita, S Sugita, 2007, Acta physiologica.

A Central Kinase Domain of Type I Phosphatidylinositol Phosphate Kinases Is Sufficient to Prime Exocytosis

S. Sugita, Li Wang, Gang Li, 2005, Journal of Biological Chemistry.

Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation

Christopher A. Piggott, S. Sugita, Na-Ryum Bin, 2013, Proceedings of the National Academy of Sciences.

Structural and functional understanding of disease-associated mutations in V-ATPase subunit a1 and other isoforms

S. Sugita, Karen Indrawinata, Peter Argiropoulos, 2023, Frontiers in Molecular Neuroscience.

Syntaxin-3 is dispensable for basal neurotransmission and synaptic plasticity in postsynaptic hippocampal CA1 neurons

Mengjia Huang, P. Monnier, Liang Zhang, 2020, Scientific Reports.

Investigating the Role of SNARE Proteins in Trafficking of Postsynaptic Receptors using Conditional Knockouts

Mengjia Huang, S. Sugita, Na-Ryum Bin, 2019, Neuroscience.

Crucial Role of Postsynaptic Syntaxin 4 in Mediating Basal Neurotransmission and Synaptic Plasticity in Hippocampal CA1 Neurons.

J. Wrana, Zhengping Jia, K. Okamoto, 2018, Cell reports.

Activators of protein kinase C mimic serotonin-induced modulation of a voltage-dependent potassium current in pleural sensory neurons of Aplysia.

D. A. Baxter, J. Byrne, S. Sugita, 1994, Journal of neurophysiology.

Modulation of a cAMP/Protein Kinase A Cascade by Protein Kinase C in Sensory Neurons of Aplysia

D. A. Baxter, J. Byrne, S. Sugita, 1997, The Journal of Neuroscience.

Munc18-1 domain-1 controls vesicle docking and secretion by interacting with syntaxin-1 and chaperoning it to the plasma membrane

Nancy T. Malintan, B. Collins, F. Meunier, 2011, Molecular biology of the cell.

Rescue of Munc18-1 and -2 double knockdown reveals the essential functions of interaction between Munc18 and closed syntaxin in PC12 cells.

Nancy T. Malintan, B. Collins, F. Meunier, 2009, Molecular Biology of the Cell.

Rescue of Munc 18-1 and-2 Double Knockdown Reveals the Essential Functions of Interaction between Munc 18 and Closed Syntaxin in PC 12 Cells

Nancy T. Malintan, B. Collins, F. Meunier, 2009 .

A Pivotal Role for Pro-335 in Balancing the Dual Functions of Munc18-1 Domain-3a in Regulated Exocytosis*

Seungmee Park, S. Sugita, Na-Ryum Bin, 2014, The Journal of Biological Chemistry.

Domain 3a of Munc18-1 plays a crucial role at the priming stage of exocytosis

S. Sugita, Na-Ryum Bin, Liping Han, 2013, Journal of Cell Science.

Munc18 Domain-3a in Exocytosis the Domain-3a of Munc18-1 Plays a Crucial Role at the Priming Stage of Exocytosis 2 3 4 5 Munc18 Domain-3a in Exocytosis 2

S. Sugita, Na-Ryum Bin, Liping Han, 2022 .

Exocytic machineries differentially control mediator release from allergen-triggered RBL-2H3 cells

S. Sugita, Hao Xu, Pratikshya Adhikari, 2023, Inflammation Research.

Chaperoning of closed syntaxin-3 through Lys46 and Glu59 in domain 1 of Munc18 proteins is indispensable for mast cell exocytosis

Hong-Shuo Sun, Ekaterina Turlova, S. Sugita, 2015, Journal of Cell Science.

Navigation through the Plasma Membrane Molecular Landscape Shapes Random Organelle Movement

Rory R. Duncan, Gabriel J. Lord, Colin Rickman, 2017, Current Biology.

Differential Regulation of Excitatory vs Inhibitory Synaptic Release by Complexin/CPX-1 and CAPS/UNC-31 at the C. elegans Neuromuscular Junctions

Shangbang Gao, Mengjia Huang, C. Zhang, 2023, bioRxiv.

Double mutation of open syntaxin and UNC-18 P334A leads to excitatory-inhibitory imbalance and impairs multiple aspects of C. elegans behavior

J. Rizo, Shangbang Gao, Mengjia Huang, 2023, bioRxiv.

Synaptotagmin 1 C 2 B Domain Triggers Fast Exocytosis without Stimulating SNARE Interactions

Christian Rosenmund, J. Rhee, Jiong Tang, 2003 .

Mouse model of multiple sclerosis induced by disrupting vesicular transport in oligodendrocytes

Zhong-Ping Feng, Hong-Shuo Sun, Mengjia Huang, 2023, bioRxiv.

ϒ-secretase and LARG mediate distinct RGMa activities to control appropriate layer targeting within the optic tectum

P. Mehlen, P. Banerjee, P. Monnier, 2015, Cell Death and Differentiation.

In Reply.

S. Sugita, G. Lonart, Liping Han, 2016, Anesthesiology.