H. Sosa

发表

X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle.

H E Huxley, A. Stewart, H. Huxley, 1994, Biophysical journal.

Single-molecule fluorescence spectroscopy and microscopy of biomolecular motors.

W E Moerner, Hernando Sosa, E. Peterman, 2004, Annual review of physical chemistry.

Distinct Interaction Modes of the Kinesin-13 Motor Domain with the Microtubule.

G. Gerfen, D. Sharp, A. Asenjo, 2016, Biophysical journal.

Kinesin-13s form rings around microtubules

V. Mennella, D. Sharp, A. Asenjo, 2006, The Journal of cell biology.

Kinesin-5 Promotes Microtubule Nucleation and Assembly by Stabilizing a Lattice-Competent Conformation of Tubulin

W. Hancock, A. Asenjo, H. Sosa, 2019, Current Biology.

Kinesin-5 Promotes Micro tubule Nucleation and Assembly by Stabilizing a Lattice-Competent Conformation of Tubulin Graphical

W. Hancock, J. M. Cleary, A. Asenjo, 2019 .

Kinesin-5 Promotes Microtubule Nucleation and Assembly by Stabilizing a Lattice-Competent Conformation of Tubulin

W. Hancock, J. M. Cleary, A. Asenjo, 2019, Current Biology.

KIF14 binds tightly to microtubules and adopts a rigor-like conformation.

A. Asenjo, B. Kwok, J. Allingham, 2014, Journal of molecular biology.

Plunge Quick Freezing Method: Myofilament Lengths

H. Huxley, D. Popp, H. Sosa, 2005 .

Three different approaches for calculating the three-dimensional structure of microtubules decorated with kinesin motor domains.

A. Hoenger, R. Milligan, H. Sosa, 1997, Journal of structural biology.

Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration

Shannon F. Stewman, J. Ross, S. Rogers, 2011, Nature Cell Biology.

Use of Single Molecule Fluorescence Polarization Microscopy to Study Protein Conformation and Dynamics of Kinesin-Microtubule Complexes.

H. Sosa, M. Benoit, 2018, Methods in molecular biology.

Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14

A. Asenjo, B. Kwok, H. Sosa, 2020, Nature Communications.

Nucleotide-free structures of Kif20A illuminate the atypical allostery in this mitotic kinesin-6

S. Rosenfeld, A. Houdusse, A. Asenjo, 2022, bioRxiv.

X-ray diffraction study of the structural changes accompanying phosphorylation of tarantula muscle

R. Padrón, H. Sosa, N. Panté, 1991, Journal of Muscle Research & Cell Motility.

Ultrastructure of skeletal muscle fibers studied by a plunge quick freezing method: myofilament lengths.

H. Huxley, D. Popp, H. Sosa, 1994, Biophysical journal.

Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis

Shannon F. Stewman, J. Ross, J. Metz, 2012, Cell cycle.

ADP-induced rocking of the kinesin motor domain revealed by single-molecule fluorescence polarization microscopy

W. E. Moerner, Erwin J.G. Peterman, Hernando Sosa, 2001, Nature Structural Biology.

Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases.

William J Rice, Hernando Sosa, M. Silvestry, 2013, Cell reports.

Cryo-EM Unveils the Processivity Mechanism of Kinesin KIF1A and the Impact of its Pathogenic Variant P305L

A. Gennerich, A. Asenjo, H. Sosa, 2023, bioRxiv.

A Second Tubulin Binding Site on the Kinesin-13 Motor Head Domain Is Important during Mitosis

M. Greenbaum, D. Sharp, A. Asenjo, 2013, PloS one.

Structure of the kinesin13-microtubule ring complex.

William J Rice, Hernando Sosa, W. Rice, 2008, Structure.

The Drosophila kinesin-13, KLP59D, impacts Pacman- and Flux-based chromosome movement.

G. C. Rogers, D. Sharp, H. Sosa, 2009, Molecular biology of the cell.

Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s

A. Asenjo, H. Sosa, M. Benoît, 2017, Nature Communications.

Motor domain phosphorylation and regulation of the Drosophila kinesin 13, KLP10A

V. Mennella, D. Sharp, A. Asenjo, 2009, The Journal of cell biology.

The Human UGT2B7 Nanodisc

T. Leyh, H. Sosa, I. Cook, 2019, Drug Metabolism and Disposition.

Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape

C. Frazer, A. Asenjo, J. Allingham, 2022, Nature Communications.

Three-dimensional structure of ncd-decorated microtubules obtained by a back-projection method.

R A Milligan, R. Milligan, H. Sosa, 1996, Journal of molecular biology.

A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion.

M. Kielian, H. Sosa, Claudia Sánchez-San Martín, 2008, Cell host & microbe.

A Model for the Microtubule-Ncd Motor Protein Complex Obtained by Cryo-Electron Microscopy and Image Analysis

Andreas Hoenger, Ronald A Milligan, Michael Whittaker, 1997, Cell.

Relationship between moiré patterns, tubulin shape, and microtubule polarity.

D. Chrétien, H. Sosa, H Sosa, 1998, Cell motility and the cytoskeleton.

A mobile kinesin-head intermediate during the ATP-waiting state

Hernando Sosa, A. Asenjo, H. Sosa, 2009, Proceedings of the National Academy of Sciences.

Configuration of the two kinesin motor domains during ATP hydrolysis

Hernando Sosa, A. Asenjo, H. Sosa, 2003, Nature Structural Biology.

Nucleotide binding and hydrolysis induces a disorder-order transition in the kinesin neck-linker region

Hernando Sosa, A. Asenjo, H. Sosa, 2006, Nature Structural &Molecular Biology.

Structure and dynamics of the kinesin-microtubule interaction revealed by fluorescence polarization microscopy.

E. Peterman, A. Asenjo, H. Sosa, 2010, Methods in cell biology.

Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6

A. Houdusse, A. Asenjo, H. Sosa, 2023, Open Biology.

A stable prefusion intermediate of the alphavirus fusion protein reveals critical features of class II membrane fusion.

M. Kielian, H. Sosa, Claudia Sánchez-San Martín, 2008, Cell host & microbe.

Polarized fluorescence microscopy of individual and many kinesin motors bound to axonemal microtubules.

W E Moerner, W. Moerner, H. Sosa, 2001, Biophysical journal.

Cryo-EM unveils kinesin KIF1A’s processivity mechanism and the impact of its pathogenic variant P305L

A. Gennerich, A. Asenjo, H. Sosa, 2024, Nature communications.