Daniel Zimmerli

Predicting and Tuning Physicochemical Properties in Lead Optimization: Amine Basicities

Manfred Kansy, Rainer E. Martin, Stefanie Bendels, 2007, ChemMedChem.

Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors.

Markus Bender, Edilio Borroni, Daniela Alberati, 2010, Bioorganic & medicinal chemistry letters.

Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia.

Alexander Alanine, Markus Bender, Edilio Borroni, 2010, Journal of medicinal chemistry.

Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery.

Manfred Kansy, Björn Wagner, Erick M Carreira, 2015, Journal of medicinal chemistry.