Klaus Müller

发表

Predicting and Tuning Physicochemical Properties in Lead Optimization: Amine Basicities

Manfred Kansy, Rainer E. Martin, Stefanie Bendels, 2007, ChemMedChem.

A fluorine scan of thrombin inhibitors to map the fluorophilicity/fluorophobicity of an enzyme active site: evidence for C-F...C=O interactions.

Paul Seiler, François Diederich, F. Diederich, 2003, Angewandte Chemie.

Enamines I. Vinyl Amine, a Theoretical Study of its Structure, electrostatic potential, and proton affinity

L. D. Brown, K. Müller, Klaus Müller, 1978 .

Generic shapes for the conformation analysis of macrocyclic structures

Klaus Gubernator, Paul R. Gerber, P. Gerber, 1988 .

Fluorine Interactions at the Thrombin Active Site: Protein Backbone Fragments HCαCO Comprise a Favorable CF Environment and Interactions of CF with Electrophiles

Manfred Kansy, Björn Wagner, Paul Seiler, 2004, Chembiochem : a European journal of chemical biology.

Structure-Based Ligand Design

Klaus Gubernator, Paul R. Gerber, Clemens Broger, 1995 .

Orthogonal multipolar interactions in structural chemistry and biology.

François Diederich, F. Diederich, K. Müller, 2005, Angewandte Chemie.

Molecular modelling contributions to serine protease and serine esterase inhibitor design

Klaus Gubernator, Paul R. Gerber, Clemens Broger, 1993 .

Fluorine in Medicinal Chemistry

Martin Stahl, Manfred Kansy, Hans-Joachim Böhm, 2004, Chembiochem : a European journal of chemical biology.

The construction of new proteins: V. A template‐assembled synthetic protein (TASP) containing both a 4‐helix bundle and β‐barrel‐like structure

Klaus Gubernator, Manfred Mutter, M. Mutter, 1989, Proteins.

Oxetanes in drug discovery: structural and synthetic insights.

Franz Schuler, Björn Wagner, Mark Rogers-Evans, 2010, Journal of medicinal chemistry.

Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery.

Manfred Kansy, Björn Wagner, Erick M Carreira, 2015, Journal of medicinal chemistry.