Qing Ruan

发表

γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.

W. Hauswirth, S. Boye, M. Boulton, 2012, Investigative ophthalmology & visual science.

Discovery of structure-based small molecular inhibitor of αB-crystallin against basal-like/triple-negative breast cancer development in vitro and in vivo

Hua-bei Jiang, Lei Xi, D. Ostrov, 2014, Breast Cancer Research and Treatment.

Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).

M. Boulton, R. Baxter, S. Li Calzi, 2011, Investigative ophthalmology & visual science.

γ-Secretase and Presenilin Mediate Cleavage and Phosphorylation of Vascular Endothelial Growth Factor Receptor-1

W. Hauswirth, S. Boye, M. Boulton, 2011, The Journal of Biological Chemistry.

Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

W. Hauswirth, S. Boye, M. Agbandje-McKenna, 2013, PloS one.

PEDF Regulates Vascular Permeability by a γ-Secretase-Mediated Pathway

M. Boulton, S. Li Calzi, M. Grant, 2011, PloS one.

Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1.

W. Hauswirth, S. Boye, A. Dizhoor, 2015, Human gene therapy.

Capsid Mutated Adeno-Associated Virus Delivered to the Anterior Chamber Results in Efficient Transduction of Trabecular Meshwork in Mouse and Rat

W. Hauswirth, S. Boye, S. Boye, 2015, PloS one.

Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development.

Lei Xi, Huabei Jiang, W. Hauswirth, 2013, Cancer letters.

β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment

Alonso Emilio, Catherine Bowes Rickman, B. de Strooper, 2012, EMBO molecular medicine.

αB-Crystallin, an Effector of Unfolded Protein Response, Confers Anti-VEGF Resistance to Breast Cancer via Maintenance of Intracrine VEGF in Endothelial Cells

W. Jiang, M. Boulton, B. Law, 2011, Molecular Cancer Research.

Connection of pericyte-angiopoietin-Tie-2 system in diabetic retinopathy: friend or foe?

Jun Cai, Qing Ruan, Song Han, 2012, Future medicinal chemistry.

Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors

S. Boye, M. Agbandje-McKenna, S. Boye, 2016, Journal of Virology.

Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness.

E. Simpson, S. Boye, M. McCall, 2015, Human molecular genetics.

Natural History of Cone Disease in the Murine Model of Leber Congenital Amaurosis Due to CEP290 Mutation: Determining the Timing and Expectation of Therapy

A. J. Roman, W. Hauswirth, A. Cideciyan, 2014, PloS one.

Gene Therapy Fully Restores Vision to the All-Cone Nrl(-/-) Gucy2e(-/-) Mouse Model of Leber Congenital Amaurosis-1.

W. Hauswirth, S. Boye, A. Dizhoor, 2015, Human gene therapy.