J. Rhein

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Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis

D. Boulware, Darlisha A Williams, M. Nicol, 2019, Journal of Pharmacokinetics and Pharmacodynamics.

Management of amphotericin-induced phlebitis among HIV patients with cryptococcal meningitis in a resource-limited setting: a prospective cohort study

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2019, BMC Infectious Diseases.

Xpert MTB/RIF Ultra for the diagnosis of HIV-associated tuberculous meningitis: a prospective validation study

D. Boulware, A. Elliott, F. Cresswell, 2020, The Lancet. Infectious diseases.

Can improved diagnostics reduce mortality from Tuberculous meningitis? Findings from a 6.5-year cohort in Uganda.

D. Boulware, A. Elliott, F. Cresswell, 2018, Wellcome open research.

The conundrum of clinical trials and standard of care in sub-Saharan Africa – the research nurse perspective

D. Boulware, Darlisha A Williams, M. Abassi, 2019, Journal of research in nursing : JRN.

Detrimental Outcomes of Unmasking Cryptococcal Meningitis With Recent ART Initiation

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2018, Open forum infectious diseases.

Improved Diagnostic Sensitivity for TB Meningitis with Xpert MTB/Rif of centrifuged CSF: a prospective study

Reuben., D. Alland, Darlisha A Williams, 2016 .

Improved diagnostic sensitivity for tuberculous meningitis with Xpert(®) MTB/RIF of centrifuged CSF.

D. Alland, D. Boulware, D. Williams, 2015, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.

Evaluation of Fingerstick Cryptococcal Antigen Lateral Flow Assay in HIV-Infected Persons: A Diagnostic Accuracy Study

D. Boulware, Darlisha A Williams, D. Meya, 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Epidemiology of meningitis in an HIV-infected Ugandan cohort.

M. Crabtree, D. Boulware, D. Boxrud, 2015, The American journal of tropical medicine and hygiene.

High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy–Experienced Human Immunodeficiency Virus–Infected Patients in Northern Uganda in the Era of “Test and Treat”: Implications for Cryptococcal Screening Programs

P. Bohjanen, D. Meya, J. Rhein, 2022, Open forum infectious diseases.

Blood neutrophil counts in HIV-infected patients with cryptococcal meningitis: Association with mortality

D. Boulware, K. H. Hullsiek, P. Bohjanen, 2018, PloS one.

Delta-like 1 protein, vitamin D binding protein and fetuin for detection of Mycobacterium tuberculosis meningitis.

D. Boulware, S. Sreevatsan, Darlisha A Williams, 2018, Biomarkers in medicine.

Cytomegalovirus viremia associated with increased mortality in cryptococcal meningitis in sub-Saharan Africa.

S. Lofgren, D. Boulware, G. Meintjes, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Cryptococcosis in pregnancy and the postpartum period: Case series and systematic review with recommendations for management.

D. Boulware, K. Pastick, C. Skipper, 2019, Medical mycology.

Accuracy of Noninvasive Intraocular Pressure or Optic Nerve Sheath Diameter Measurements for Predicting Elevated Intracranial Pressure in Cryptococcal Meningitis

D. Boulware, A. Kiragga, D. Meya, 2014, Open forum infectious diseases.

Cerebrospinal Fluid and Brain Tissue Penetration of Tenofovir, Lamivudine, and Efavirenz in Postmortem Tissues with Cryptococcal Meningitis

D. Boulware, R. Lukande, Darlisha A Williams, 2019, Clinical and translational science.

Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy.

D. Boulware, P. Bohjanen, M. Kamya, 2008, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Utility of the monocyte to lymphocyte ratio in diagnosing latent tuberculosis among HIV-infected individuals with a negative tuberculosis symptom screen

C. Sekaggya-Wiltshire, D. Meya, J. Rhein, 2020, PloS one.

Diagnostic performance of a multiplex PCR assay for meningitis in an HIV-infected population in Uganda.

D. Boulware, J. Cloud, Darlisha A Williams, 2016, Diagnostic microbiology and infectious disease.

Prognosis and management of cryptococcal meningitis in patients with human immunodeficiency virus infection

D. Boulware, J. Rhein, Joshua Rhein, 2012 .

Adjunctive sertraline for HIV-associated cryptococcal meningitis: a randomised, placebo-controlled, double-blind phase 3 trial.

D. Boulware, K. Huppler Hullsiek, Darlisha A Williams, 2019, The Lancet. Infectious diseases.

Erratum: The effect of therapeutic lumbar punctures on acute mortality from cryptococcal meningitis (Clinical Infectious Diseases (2014) 59 (1607-1614))

K. H. Hullsiek, M. Rolfes, J. Rhein, 2015 .

Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA–vaccinated patients with inflammatory bowel disease

A. Khoruts, T. Schacker, M. Jenkins, 2022, JCI insight.

Efficacy of Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis: an open-label dose-ranging study

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2016, The Lancet. Infectious diseases.

Cryptococcal Meningitis: Diagnosis and Management Update

D. Boulware, M. Abassi, J. Rhein, 2015, Current Tropical Medicine Reports.

Increased Antifungal Drug Resistance in Clinical Isolates of Cryptococcus neoformans in Uganda

D. Boulware, K. H. Hullsiek, Tami R. McDonald, 2015, Antimicrobial Agents and Chemotherapy.

AIDS-related mycoses: the way forward.

Lisa M. Graham, M. Netea, A. Casadevall, 2014, Trends in microbiology.

ATI-2307 Exhibits Equivalent Antifungal Activity in Cryptococcus neoformans Clinical Isolates With High and Low Fluconazole IC50

Elliot S. Gerlach, D. Boulware, Kirsten Nielsen, 2021, Frontiers in Cellular and Infection Microbiology.

OUTCOMES OF CRYPTOCOCCAL MENINGITIS IN UGANDA BEFORE AND AFTER THE AVAILABILITY OF HAART

D. Boulware, P. Bohjanen, M. Kamya, 2008 .

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones

Chaim A. Schramm, Alexander M Schrager, J. Mascola, 2022, bioRxiv.

Chronic pulmonary aspergillosis in patients with active pulmonary tuberculosis with persisting symptoms in Uganda

S. Prasad, D. Denning, C. Sekaggya-Wiltshire, 2022, Mycoses.

The effect of sertraline on depression and associations with persistent depression in survivors of HIV-related cryptococcal meningitis

S. Lofgren, N. Nakasujja, D. Boulware, 2021, Wellcome Open Research.

The Changing Epidemiology of HIV-Associated Adult Meningitis, Uganda 2015–2017

D. Boulware, F. Cresswell, A. Bangdiwala, 2019, Open forum infectious diseases.

Minimum Inhibitory Concentration Distribution of Fluconazole Against Cryptococcus Species and the Fluconazole Exposure Prediction Model

D. Boulware, C. Skipper, M. Nicol, 2019, Open forum infectious diseases.

Recent advances in AIDS-related cryptococcal meningitis treatment with an emphasis on resource limited settings

S. Lofgren, D. Boulware, M. Abassi, 2017, Expert review of anti-infective therapy.

Sertraline for HIV-associated cryptococcal meningitis - Authors' reply.

D. Boulware, Kirsten Nielsen, D. Meya, 2016, The Lancet. Infectious diseases.

Evaluation of the BioFire® FilmArray® Meningitis/Encephalitis panel in an adult and pediatric Ugandan population.

D. Boulware, K. H. Hullsiek, F. Cresswell, 2021, Journal de mycologie medicale.

Evaluation of the Diagnostic Performance of a Semiquantitative Cryptococcal Antigen Point-of-Care Assay among HIV-Infected Persons with Cryptococcal Meningitis

D. Boulware, Darlisha A Williams, C. Skipper, 2021, Journal of clinical microbiology.

Evaluation of the Dynamiker Cryptococcal Antigen Lateral Flow Assay for the Diagnosis of HIV-Associated Cryptococcosis

D. Boulware, Darlisha A Williams, D. Meya, 2020, Journal of Clinical Microbiology.

Evaluation of Serum Cryptococcal Antigen Testing Using Two Novel Semiquantitative Lateral Flow Assays in Persons with Cryptococcal Antigenemia

D. Boulware, C. Skipper, R. Rajasingham, 2020, Journal of Clinical Microbiology.

Cerebrospinal Fluid Early Fungicidal Activity as a Surrogate Endpoint for Cryptococcal Meningitis Survival in Clinical Trials

D. Boulware, S. Bangdiwala, G. Meintjes, 2020 .

Evaluation of a point-of-care immunoassay test kit ‘StrongStep’ for cryptococcal antigen detection

D. Boulware, Darlisha A Williams, Liliane Mukaremera, 2018, PloS one.

Reproducibility of CSF quantitative culture methods for estimating rate of clearance in cryptococcal meningitis.

D. Boulware, J. Dyal, Darlisha A Williams, 2016, Medical mycology.

Detection of High Cerebrospinal Fluid Levels of (1→3)-β-d-Glucan in Cryptococcal Meningitis

D. Boulware, Yonglong Zhang, M. Finkelman, 2014, Open forum infectious diseases.

Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis.

D. Boulware, P. Bohjanen, G. Meintjes, 2014, The New England journal of medicine.

Standardized Electrolyte Supplementation and Fluid Management Improves Survival During Amphotericin Therapy for Cryptococcal Meningitis in Resource-Limited Settings

D. Boulware, A. Kambugu, M. Rolfes, 2014, Open forum infectious diseases.

The Effect of Therapeutic Lumbar Punctures on Acute Mortality From Cryptococcal Meningitis

D. Boulware, K. H. Hullsiek, G. Meintjes, 2014, Clinical Infectious Diseases.

Diagnosis and Management of Cryptococcal Relapse.

D. Boulware, D. Meya, J. Rhein, 2013, Journal of AIDS & clinical research.

Clinical Features and Serum Biomarkers in HIV Immune Reconstitution Inflammatory Syndrome after Cryptococcal Meningitis: A Prospective Cohort Study

Tracy L. Bergemann, Joshua Rhein, David R. Boulware, 2010, PLoS medicine.

Cerebrospinal Fluid Culture Positivity and Clinical Outcomes After Amphotericin-Based Induction Therapy for Cryptococcal Meningitis

D. Boulware, P. Bohjanen, G. Meintjes, 2015, Open forum infectious diseases.

Emerging fluconazole resistance: Implications for the management of cryptococcal meningitis

M. Abassi, J. Rhein, Edward Mpoza, 2017, Medical mycology case reports.

Central nervous system cryptococcoma in a Ugandan patient with Human Immunodeficiency Virus

D. Boulware, J. Rhein, A. Musubire, 2014, Medical mycology case reports.

Phase I EnACT Trial of the Safety and Tolerability of a Novel Oral Formulation of Amphotericin B

D. Boulware, K. H. Hullsiek, R. Mannino, 2020, Antimicrobial Agents and Chemotherapy.

Safety and tolerability of a novel oral formulation of amphotericin B: Phase I EnACT Trial 1

D. Boulware, K. H. Hullsiek, R. Mannino, 2020 .

Impact of biological sex on cryptococcal meningitis mortality in Uganda and South Africa.

S. Lofgren, D. Boulware, K. H. Hullsiek, 2021, Medical mycology.

1468Detection of High CSF Levels of (1 → 3)-Beta-D-Glucan in Cryptococcal Meningitis

D. Boulware, M. Finkelman, G. Meintjes, 2014, Open Forum Infectious Diseases.

Therapeutic Lumbar Punctures in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis: Should Opening Pressure Direct Management?

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2022, Open forum infectious diseases.

Unmasking histoplasmosis immune reconstitution inflammatory syndrome in a patient recently started on antiretroviral therapy

R. Lukande, J. Rhein, R. Kiggundu, 2016, Autopsy & case reports.

Acute Kidney Injury and Urinary Biomarkers in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis

D. Boulware, G. Meintjes, C. Schutz, 2017, Open forum infectious diseases.

Brief Report: Effects of Tenofovir and Amphotericin B Deoxycholate Coadministration on Kidney Function in Patients Treated for Cryptococcal Meningitis

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2016, Journal of acquired immune deficiency syndromes.

Prognostic implications of baseline anaemia and changes in haemoglobin concentrations with amphotericin B therapy for cryptococcal meningitis

D. Boulware, K. H. Hullsiek, D. Williams, 2017, HIV medicine.

Impact of community engagement and social support on the outcomes of HIV-related meningitis clinical trials in a resource-limited setting

L. Haddow, S. Lofgren, D. Boulware, 2020, Research Involvement and Engagement.

Sterile Cerebrospinal Fluid Culture at Cryptococcal Meningitis Diagnosis Is Associated with High Mortality

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2022, Journal of fungi.

Cytomegalovirus viremia as a risk factor for mortality in HIV-associated cryptococcal and tuberculous meningitis

D. Boulware, K. H. Hullsiek, M. Schleiss, 2022, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Cerebrospinal Fluid Lactate as a Prognostic Marker of Disease Severity and Mortality in Cryptococcal Meningitis.

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Standardized Urine-Based Tuberculosis (TB) Screening With TB-Lipoarabinomannan and Xpert MTB/RIF Ultra in Ugandan Adults With Advanced Human Immunodeficiency Virus Disease and Suspected Meningitis

D. Boulware, A. Elliott, F. Cresswell, 2020, Open forum infectious diseases.

Symptomatic Cryptococcal Antigenemia Presenting as Early Cryptococcal Meningitis With Negative Cerebral Spinal Fluid Analysis.

S. Lofgren, D. Boulware, K. H. Hullsiek, 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Tuberculous meningitis diagnosis and outcomes during the Xpert MTB/Rif era: a 6.5-year cohort study in Uganda

D. Boulware, A. Elliott, F. Cresswell, 2018, Wellcome open research.

Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study

D. Boulware, K. H. Hullsiek, C. Denkinger, 2018, The Lancet. Infectious diseases.

Cryptococcal Disease in the Era of “Test and Treat”: Is There Cause for Concern?

D. Boulware, M. Abassi, D. Meya, 2017, Open forum infectious diseases.

Evolving Failures in the Delivery of Human Immunodeficiency Virus Care: Lessons From a Ugandan Meningitis Cohort 2006–2016

D. Boulware, M. Roediger, K. H. Hullsiek, 2017, Open forum infectious diseases.

Baseline Serum C-Reactive Protein Level Predicts Mortality in Cryptococcal Meningitis

D. Boulware, K. H. Hullsiek, Darlisha A Williams, 2019, Open forum infectious diseases.

CSF early fungicidal activity as a surrogate endpoint for cryptococcal meningitis survival in clinical trials.

D. Boulware, K. H. Hullsiek, G. Meintjes, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Cryptococcal Meningitis and Tuberculous Meningitis Co-infection in HIV-Infected Ugandan Adults

D. Boulware, F. Cresswell, J. Rhein, 2018, Open forum infectious diseases.

Early ART After Cryptococcal Meningitis Is Associated With Cerebrospinal Fluid Pleocytosis and Macrophage Activation in a Multisite Randomized Trial

D. Boulware, K. H. Hullsiek, G. Meintjes, 2015, The Journal of infectious diseases.

Retroperitoneal Actinomycosis: A Rare Sequela of an Infected Obstructing Ureteral Stone

J. Rhein, M. Borofsky, E. Bearrick, 2017, Journal of endourology case reports.

HIV-Associated Cryptococcal Meningitis Occurring at Relatively Higher CD4 Counts

S. Lofgren, D. Boulware, K. H. Hullsiek, 2018, The Journal of infectious diseases.

Cryptococcal Antigenemia in Human Immunodeficiency Virus Antiretroviral Therapy–Experienced Ugandans With Virologic Failure

D. Boulware, I. Ssewanyana, R. Rajasingham, 2019, Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America.

Neurocognitive function in HIV-infected persons with asymptomatic cryptococcal antigenemia: a comparison of three prospective cohorts

N. Nakasujja, D. Boulware, P. Bohjanen, 2017, BMC Neurology.

A secondary analysis of depression outcomes from a randomized controlled trial of adjunctive sertraline for HIV-associated cryptococcal meningitis

S. Lofgren, N. Nakasujja, D. Boulware, 2022, Wellcome Open Research.

Tuberculosis in HIV-Associated Cryptococcal Meningitis is Associated with an Increased Risk of Death

D. Boulware, K. H. Hullsiek, F. Cresswell, 2020, Journal of clinical medicine.

Differences in Immunologic Factors Among Patients Presenting with Altered Mental Status During Cryptococcal Meningitis

S. Lofgren, D. Boulware, K. H. Hullsiek, 2017, The Journal of infectious diseases.

Prevalence and nature of potential drug-drug interactions among hospitalized HIV patients presenting with suspected meningitis in Uganda

D. Boulware, K. H. Hullsiek, M. Nicol, 2020, BMC Infectious Diseases.

High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines

A. Khoruts, T. Schacker, M. Jenkins, 2021, Cell Reports.

Convergent epitope specificities, V gene usage and public clones elicited by primary exposure to SARS-CoV-2 variants.

Chaim A. Schramm, Alexander M Schrager, J. Mascola, 2022, bioRxiv : the preprint server for biology.

Culture-negative cryptococcal meningitis.

C. Skipper, J. Rhein, K. Ssebambulidde, 2019, The Lancet. Infectious diseases.

Symptomatic cryptococcal antigenemia presenting as early cryptococcal meningitis with negative CSF analysis

D. Boulware, K. H. Hullsiek, F. Cresswell, 2019 .

Clinical mycology today: A synopsis of the mycoses study group education and research consortium (MSGERC) second biennial meeting, September 27-30, 2018, Big Sky, Montana, a proposed global research agenda.

L. Pirofski, B. Jackson, R. Wynn, 2020, Medical mycology.

Cryptococcal Antigenemia in HIV therapy-experienced Ugandans with Virologic Failure.

D. Boulware, I. Ssewanyana, R. Rajasingham, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Human Immune Response Varies by the Degree of Relative Cryptococcal Antigen Shedding

D. Boulware, Tami R. McDonald, G. Meintjes, 2015, Open forum infectious diseases.

Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation

D. Boulware, D. Meya, J. Rhein, 2014, Medical mycology case reports.

1,3-β-D-glucan in cryptococcal meningitis.

D. Boulware, J. Rhein, N. Bahr, 2015, The Lancet. Infectious diseases.

Implementation of an Anticoagulation Practice Guideline for COVID-19 via a Clinical Decision Support System in a Large Academic Health System and Its Evaluation: Observational Study (Preprint)

Deborah L. Pestka, G. Melton, N. Shippee, 2021 .

Implementation of an Anticoagulation Practice Guideline for COVID-19 via a Clinical Decision Support System in a Large Academic Health System and Its Evaluation: Observational Study

Deborah L. Pestka, G. Melton, N. Shippee, 2021, JMIR medical informatics.

Antiretroviral Therapy Down-Regulates Innate Antiviral Response Genes in Patients With AIDS in Sub-Saharan Africa

D. Boulware, P. Bohjanen, A. Kambugu, 2010, Journal of acquired immune deficiency syndromes.