S. Pimplikar

发表

Reassessing the amyloid cascade hypothesis of Alzheimer's disease.

S. Pimplikar, Sanjay W Pimplikar, 2009, The international journal of biochemistry & cell biology.

Association of the Herpes Simplex Virus Type 1 Us11 Gene Product with the Cellular Kinesin Light-Chain-Related Protein PAT1 Results in the Redistribution of Both Polypeptides

I. Mohr, S. Pimplikar, M. Mulvey, 2003, Journal of Virology.

Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane

M. Zerial, L. Huber, R. Parton, 1993, The Journal of cell biology.

PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein.

S. Pimplikar, S. V. Vande Pol, P. Zheng, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Basolateral protein transport in streptolysin O-permeabilized MDCK cells

E. Ikonen, K. Simons, S. Pimplikar, 1994, The Journal of cell biology.

Regulation of apical transport in epithelial cells by a Gsclass of heterotrimeric G protein

K. Simons, S. Pimplikar, 1993, Nature.

Regulation of nuclear functions--nucleocytoplasmic transport in context.

T. Weimbs, A. Tartakoff, A. Matera, 2004, European journal of cell biology.

JNK-interacting protein 1 mediates Alzheimer's-like pathological features in AICD-transgenic mice

Chinthasagar Bastian, S. Pimplikar, Q. Fan, 2015, Neurobiology of Aging.

Role of heterotrimeric G proteins in polarized membrane transport

K. Simons, S. Pimplikar, 1993, Journal of Cell Science.

Activators of protein kinase A stimulate apical but not basolateral transport in epithelial Madin-Darby canine kidney cells.

K. Simons, S. Pimplikar, 1994, The Journal of biological chemistry.

Abnormal neuronal networks and seizure susceptibility in mice overexpressing the APP intracellular domain

D. Bredesen, B. Lamb, V. Galvan, 2011, Neurobiology of Aging.

AβPP, apoptosis and Alzheimer's disease

S. Pimplikar, 2002 .

AβPP, Apoptosis and Alzheimer's disease Commentary on: Neuronal apoptosis is accompanied by amyloid β-protein accumulation in the endoplasmic reticulum

S. Pimplikar, 2002 .

Multi-omics and Alzheimer's disease: a slower but surer path to an efficacious therapy?

S. Pimplikar, 2017, American journal of physiology. Cell physiology.

Biogenesis of cell-surface polarity in epithelial cells and neurons.

L. Huber, P. Dupree, K. Simons, 1992, Cold Spring Harbor symposia on quantitative biology.

Sphingolipid transport from the trans‐Golgi network to the apical surface in permeabilized MDCK cells

R. Parton, K. Simons, S. Bhakdi, 1992, FEBS letters.

Chromogranin B (secretogranin I), a secretory protein of the regulated pathway, is also present in a tightly membrane-associated form in PC12 cells.

W. Huttner, S. Pimplikar, 1992, The Journal of biological chemistry.

Analysis of erythrocyte membrane proteins from dystrophic hamsters

S. Pimplikar, S. Malhotra, S. W. Pimplikar, 1983, FEBS letters.

The γ-secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

S. Pimplikar, Yuehua Gao, 2001, Proceedings of the National Academy of Sciences of the United States of America.

PAT1 induces cell death signal and SET mislocalization into the cytoplasm by increasing APP/APLP2 at the cell surface

B. Allinquant, S. Pimplikar, P. Facchinetti, 2011, Neurobiology of Aging.

What the granins tell us about the formation of secretory granules in neuroendocrine cells

W. Huttner, S. Pimplikar, J. Stinchcombe, 1991, Cell Biophysics.

Aging and excitotoxic stress exacerbate neural circuit reorganization in amyloid precursor protein intracellular domain transgenic mice

S. Pimplikar, Kaushik Ghosal, 2011, Neurobiology of Aging.

Structure and Function of the Band 3 Cl‐/HCO‐3 Transporter a

J. Casey, R. Reithmeier, S. Pimplikar, 1989, Annals of the New York Academy of Sciences.

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

R. Ransohoff, S. Staugaitis, G. Landreth, 2015, The Journal of experimental medicine.

Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth.

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2005, Molecular endocrinology.

Neuroinflammation in Alzheimer’s Disease: from Pathogenesis to a Therapeutic Target

S. Pimplikar, 2014, Journal of Clinical Immunology.

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

T. Goiran, E. Duplan, Lila Rouland, 2017, Biological Psychiatry.

Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis

Li-Huei Tsai, Ralph A. Nixon, L. Tsai, 2010, The Journal of Neuroscience.

inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models

R. Ransohoff, S. Staugaitis, G. Landreth, 2015 .

When neurogenesis encounters aging and disease

Henriette van Praag, Mark P. Mattson, M. Mattson, 2010, Trends in Neurosciences.

Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease

K. Herrup, B. Lamb, Nicholas H. Varvel, 2008, The Journal of Neuroscience.

Amyloid precursor protein is required for convergent-extension movements during Zebrafish development.

S. Pimplikar, Powrnima Joshi, J. Sullivan, 2009, Developmental biology.

Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer’s-Like Pathological Features in Mice

S. Pimplikar, H. Dawson, Q. Fan, 2016, PloS one.

Response to Correspondence: Pardossi-Piquard et al., “Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP.” Neuron 46, 541–554

P. George-Hyslop, J. Dunys, F. Checler, 2007, Neuron.

APP Intracellular Domain Impairs Adult Neurogenesis in Transgenic Mice by Inducing Neuroinflammation

S. Pimplikar, Kaushik Ghosal, A. Stathopoulos, 2010, PloS one.

Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain

S. Pimplikar, K. Ryan, 2005, The Journal of cell biology.

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain

Yong Shen, B. Lamb, S. Pimplikar, 2009, Proceedings of the National Academy of Sciences.

Amyloid precursor protein: more than just neurodegeneration

S. Pimplikar, Kaushik Ghosal, 2011, Stem cell research & therapeutics.

The Apolipoprotein-E-Mimetic COG112 Protects Amyloid Precursor Protein Intracellular Domain-Overexpressing Animals from Alzheimer's Disease-Like Pathological Features

M. Vitek, S. Pimplikar, Dustin Thomas, 2012, Neurodegenerative Diseases.

Detection of APP intracellular domain in brain tissue.

S. Pimplikar, A. Suryanarayana, 2011, Methods in molecular biology.

Knockdown of Amyloid Precursor Protein in Zebrafish Causes Defects in Motor Axon Outgrowth

Ping Song, S. Pimplikar, 2012, PloS one.

Decrease in levels of the evolutionarily conserved microRNA miR-124 affects oligodendrocyte numbers in Zebrafish, Danio rerio

B. Trapp, Ping Song, S. Pimplikar, 2015, Invertebrate Neuroscience.

Clinical and biomarker changes in Alzheimer's disease.

S. Pimplikar, 2012, The New England journal of medicine.

Kidney, liver, erythrocyte membrane Na, K-adenosine triphosphatase in protein-energy malnourished rats.

S. Pimplikar, S. Kaplay, 1981, Biochemical medicine.

When neurogenesis encounters aging and disease

M. Mattson, H. Praag, D. Peterson, 2010, Trends in Neurosciences.

Reassessing the amyloid cascade hypothesis of Alzheimer's disease.

S. Pimplikar, 2009, The international journal of biochemistry & cell biology.

Amyloid precursor protein: more than just neurodegeneration

S. Pimplikar, Kaushik Ghosal, 2011, Stem Cell Research & Therapy.