C. Colas

发表

Discrimination of agonists versus antagonists of nicotinic ligands based on docking onto AChBP structures.

Michael Nilges, Antoine Taly, Claire Colas, 2011, Journal of molecular graphics & modelling.

Ligand Discovery for the Nutrient Transporters ASCT2 and LAT‐1 from Homology Modeling and Virtual Screening

A. Schlessinger, C. Colas, Claire Colas, 2017 .

Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

A. Schlessinger, M. Bonomi, J. Holst, 2015 .

From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins.

F. Roussi, B. Iorga, V. Dumontet, 2014, Chemical communications.

LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs.

A. Schlessinger, K. Giacomini, Lawrence Lin, 2016, Bioorganic & medicinal chemistry letters.

Studies of structural determinants of substrate binding in the Creatine Transporter (CreaT, SLC6A8) using molecular models

G. Ecker, C. Colas, Giulia Banci, 2020, Scientific Reports.

Lobeline Docking on AChBP and Nicotinic Receptors: Discriminating Importance of the Pocket Geometry and of the Ligand Configuration

M. Nilges, T. Malliavin, D. Joseph, 2012 .

SLC Transporters: Structure, Function, and Drug Discovery.

A. Schlessinger, P. Ung, C. Colas, 2016, MedChemComm.

Identification of mitochondrial toxicants by combined in silico and in vitro studies – A structure-based view on the adverse outcome pathway

G. Ecker, M. Leist, B. Water, 2020, Computational Toxicology.

l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.

A. Schlessinger, K. Giacomini, C. Colas, 2019, Bioorganic & medicinal chemistry letters.

Computing Substrate Selectivity in a Peptide Transporter.

A. Schlessinger, C. Colas, David E. Smith, 2016, Cell chemical biology.

Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1.

Loëtitia Favre, M. Raphaël, F. Roussi, 2014, Bioorganic & medicinal chemistry letters.

Chemical Modulation of the Human Oligopeptide Transporter 1, hPepT1.

A. Schlessinger, S. Miyauchi, C. Colas, 2017, Molecular pharmaceutics.

Effects of Hydroxylated Mephedrone Metabolites on Monoamine Transporter Activity in vitro

H. Sitte, G. Ecker, M. Mihovilovic, 2021, Frontiers in Pharmacology.

LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates.

A. Schlessinger, K. Giacomini, Lawrence Lin, 2016, Bioorganic & medicinal chemistry letters.

Mutations in the Na+/Citrate Cotransporter NaCT (SLC13A5) in Pediatric Patients with Epilepsy and Developmental Delay

A. Schlessinger, B. Porter, A. Pajor, 2016, Molecular medicine.

Effects of Mutations and Ligands on the Thermostability of the l-Arginine/Agmatine Antiporter AdiC and Deduced Insights into Ligand-Binding of Human l-Type Amino Acid Transporters

A. Schlessinger, D. Fotiadis, C. Colas, 2018, International journal of molecular sciences.

Identification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC.

T. Malliavin, P. Corringer, C. Van Renterghem, 2013, Journal of medicinal chemistry.

The RESOLUTE consortium: unlocking SLC transporters for drug discovery

D. Kell, G. Superti-Furga, R. Everley, 2020, Nature Reviews Drug Discovery.

ATP modulates SLC7A5 (LAT1) synergistically with cholesterol

G. Ecker, C. Colas, Tiziano Mazza, 2020, Scientific Reports.

Studies of structural determinants of substrate binding in the Creatine Transporter (CreaT, SLC6A8) using molecular models

G. Ecker, C. Colas, Giulia Banci, 2020, Scientific Reports.

Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2

A. Schlessinger, J. Holst, C. Grewer, 2018, Front. Chem..

Toward a Systematic Structural and Functional Annotation of Solute Carriers Transporters—Example of the SLC6 and SLC7 Families

C. Colas, Claire Colas, 2020, Frontiers in Pharmacology.

Targeting Solute Carrier Transporters through Functional Mapping.

É. Laine, C. Colas, Claire Colas, 2020, Trends in pharmacological sciences.

Structure-Based Identification of Inhibitors for the SLC13 Family of Na(+)/Dicarboxylate Cotransporters.

A. Schlessinger, A. Pajor, C. Colas, 2015, Biochemistry.

Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

Avner Schlessinger, Massimiliano Bonomi, Thomas Albers, 2015, PLoS Comput. Biol..

Determinants of Substrate and Cation Transport in the Human Na+/Dicarboxylate Cotransporter NaDC3*

A. Schlessinger, A. Pajor, C. Colas, 2014, The Journal of Biological Chemistry.

Structure activity relationships of benzylproline-derived inhibitors of the glutamine transporter ASCT2.

A. Schlessinger, C. Grewer, C. Colas, 2017, Bioorganic & medicinal chemistry letters.

Efficiency of an Optimized Care Organization in Fibromyalgia Patients: The From Intent to Move (FIMOUV) Study Protocol of a Randomized Controlled Trial

F. Roche, L. Féasson, C. Créac’h, 2021, Frontiers in Public Health.

Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).

A. Schlessinger, K. Giacomini, D. Fotiadis, 2018, Journal of medicinal chemistry.

Understanding Experiences of Fibromyalgia Patients Involved in the Fimouv Study During COVID-19 Lockdown

L. Féasson, A. Jumel, C. Colas, 2021, Frontiers in Psychology.

Targeting SLC transporters: small molecules as modulators and therapeutic opportunities.

A. Schlessinger, C. Colas, Nicole Zatorski, 2023, Trends in biochemical sciences.