U. Schellenberger

发表

Efficient tumor killing and minimal cytokine release with novel T-cell agonist bispecific antibodies

A. Boudreau, N. Trinklein, O. Vafa, 2019, mAbs.

Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release

A. Boudreau, N. Trinklein, S. Kwek, 2021, Journal for ImmunoTherapy of Cancer.

Detection of Endogenous B-Type Natriuretic Peptide at Very Low Concentrations in Patients With Heart Failure

R. Nelson, S. Menon, U. Kiernan, 2008, Circulation. Heart failure.

Comparison of Mass Spectrometry and Clinical Assay Measurements of Circulating Fragments of B-Type Natriuretic Peptide in Patients With Chronic Heart Failure

A. Jaffe, Regis Perichon, U. Schellenberger, 2011, Circulation. Heart failure.

Clinical Implications of Defective B‐Type Natriuretic Peptide

S. Menon, R. Mills, A. Protter, 2009, Clinical cardiology.

Myocardial Contrast Echocardiography Can Be Used to Assess the Microvascular Response to Vascular Endothelial Growth Factor-121

J. Abraham, F. Villanueva, G. Schreiner, 2002, Circulation.

An apparatus for continuous analysis of protease-catalyzed acyl transfer reactions.

V. Schellenberger, H. Jakubke, Y. Mitin, 1987, Analytical biochemistry.

A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer

Harbani K. Malik-Chaudhry, A. Boudreau, N. Trinklein, 2022, Oncoimmunology.

Chemotherapeutic drug activation of the AP24 protease in apoptosis: requirement for caspase 3-like-proteases.

Y. Wang, H. Wang, S. C. Wright, 1998, Biochemical and biophysical research communications.

The precursor to B-type natriuretic peptide is an O-linked glycoprotein.

N. S. Pollitt, R. Jue, A. Protter, 2006, Archives of biochemistry and biophysics.

TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity

A. Poupon, E. Chini, M. Cuturi, 2022, mAbs.

Cloning, expression, purification, and characterization of 2'-deoxyuridylate hydroxymethylase from phage SPO1.

D. Santi, L. Livi, U. Schellenberger, 1995, Protein expression and purification.

Evidence for functional heterogeneity of circulating B-type natriuretic peptide.

Faquan Liang, Jessica O'Rear, Ute Schellenberger, 2007, Journal of the American College of Cardiology.

Activation of CPP 32-like Proteases Is Not Sufficient to Trigger Apoptosis : Inhibition of Apoptosis by Agents that Suppress Activation of AP 24 , but Not CPP 32-like Activity

J. Larrick, Hong Wang, S. C. Wright, 1997 .

Activation of CPP32-like Proteases Is Not Sufficient to Trigger Apoptosis: Inhibition of Apoptosis by Agents that Suppress Activation of AP24, but Not CPP32-like Activity

J. Larrick, Hong Wang, S. C. Wright, 1997, The Journal of experimental medicine.

Protease‐catalyzed peptide synthesis using inverse substrates: The synthesis of Pro‐Xaa‐bonds by trypsin

V. Schellenberger, H. Jakubke, Y. Mitin, 1991, Biotechnology and bioengineering.

Characterization of the S'-subsite specificity of porcine pancreatic elastase.

V. Schellenberger, H. Jakubke, Y. Mitin, 1989, European journal of biochemistry.

Sequence-Based Discovery Demonstrates That Fixed Light Chain Human Transgenic Rats Produce a Diverse Repertoire of Antigen-Specific Antibodies

Michael J. Osborn, A. Boudreau, N. Trinklein, 2018, Frontiers in Immunology.

Calmodulin‐dependent protein kinase II mediates signal transduction in apoptosis

J. Larrick, S. C. Wright, U. Schellenberger, 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Characterization of the S'-subsite specificity of bovine pancreatic alpha-chymotrypsin via acyl transfer to added nucleophiles.

V. Schellenberger, H. Jakubke, Y. Mitin, 1990, European journal of biochemistry.

TNB585.001: A multicenter, phase 1, open-label, dose-escalation and expansion study of tnb-585, a bispecific T-cell engager targeting PSMA in subjects with metastatic castrate resistant prostate cancer.

L. Fong, Duy Pham, U. Schellenberger, 2021 .

TNB-486 induces potent tumor cell cytotoxicity coupled with low cytokine release in preclinical models of B-NHL

Harbani K. Malik-Chaudhry, A. Boudreau, N. Trinklein, 2021, mAbs.

A selective insecticidal protein from Pseudomonas for controlling corn rootworms

Amit Sethi, Jian-zhou Zhao, A. Lu, 2016, Science.

Cysteine 116 participates in intermolecular bonding of the human VEGF(121) homodimer.

R. Jue, U. Schellenberger, N. Gaspar, 2002, Archives of biochemistry and biophysics.

Crystal structures of a unique thermal-stable thymidylate synthase from Bacillus subtilis.

R. Stroud, D. Santi, U. Schellenberger, 1998, Biochemistry.

Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies

Michael J. Osborn, A. Boudreau, N. Trinklein, 2019, Front. Immunol..

A bispecific antibody agonist of the IL-2 heterodimeric receptor preferentially promotes in vivo expansion of CD8 and NK cells

Harbani K. Malik-Chaudhry, A. Boudreau, N. Trinklein, 2021, Scientific Reports.

Targeted In Vivo Labeling of Receptors for Vascular Endothelial Growth Factor

William R. Wagner, Flordeliza S. Villanueva, Alexander L. Klibanov, 2003, Circulation.

Partial restoration of activity to Lactobacillus casei thymidylate synthase following inactivation by domain deletion.

B. Shoichet, D. Santi, P. Balaram, 1994, Biochemistry.

A selective insecticidal protein from Pseudomonas mosselii for corn rootworm control

A. Kassa, N. Yalpani, Jian-zhou Zhao, 2017, Plant biotechnology journal.

Pre-clinical development of TNB-383B, a fully human T-cell engaging bispecific antibody targeting BCMA for the treatment of multiple myeloma.

N. Trinklein, S. F. Aldred, Duy Pham, 2018 .

T Cell Engagement without Cytokine Storm: A Novel Bcma x CD3 Antibody Killing Myeloma Cells with Minimal Cytokine Secretion

N. Trinklein, S. F. Aldred, Duy Pham, 2017 .

Multispecific Antibody Development Platform Based on Human Heavy Chain Antibodies.

Michael J. Osborn, A. Boudreau, N. Trinklein, 2019 .

Chyhotrypsin-catalyzed fragment coupling synthesis of D-Phe(6)-GnRH

E. Krause, V. Schellenberger, H. Jakubke, 1990 .

Development of a fully human t-cell engaging bispecific antibody for the treatment of multiple myeloma.

N. Trinklein, S. F. Aldred, Duy Pham, 2017 .

Evidence for functional heterogeneity of circulating B-type natriuretic peptide.

A. Maisel, M. Lasecki, N. S. Pollitt, 2007, Journal of the American College of Cardiology.

Activation of CPP32-like Proteases Is Not Sufficient to Trigger Apoptosis: Inhibition of Apoptosis by Agents that Suppress Activation of AP24, but Not CPP32-like Activity

J. Larrick, Hong Wang, S. C. Wright, 1997, The Journal of experimental medicine.

TNB-486, a Novel Fully Human Bispecific CD19 x CD3 Antibody That Kills CD19-Positive Tumor Cells with Minimal Cytokine Secretion

A. Boudreau, N. Trinklein, S. F. Aldred, 2019, Blood.

Multispecific antibodies targeting CD38 show potent tumor-specific cytotoxicity.

A. Boudreau, N. Trinklein, S. F. Aldred, 2018 .