K. Broos

发表

A versatile T cell-based assay to assess therapeutic antigen-specific PD-1-targeted approaches

Z. Berneman, H. Sugiyama, Q. Lecocq, 2018, Oncotarget.

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.

H. Hammad, R. Schiffelers, C. Pichon, 2018, ACS nano.

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon

C. Heirman, K. Thielemans, C. Goyvaerts, 2016, Molecular therapy. Nucleic acids.

Anti-Human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation

C. Vanhove, N. Devoogdt, Q. Lecocq, 2020, Biomolecules.

Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy

N. Devoogdt, Q. Lecocq, K. Breckpot, 2018, Theranostics.

Particle-mediated Intravenous Delivery of Antigen mRNA Results in Strong Antigen-specific T-cell Responses Despite the Induction of Type I Interferon.

C. Heirman, K. Thielemans, C. Goyvaerts, 2016, Molecular therapy. Nucleic acids.

Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.

H. Hammad, R. Schiffelers, C. Pichon, 2018, ACS nano.

Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production

N. Devoogdt, Q. Lecocq, K. Thielemans, 2019, Vaccines.

Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent

N. Devoogdt, Q. Lecocq, S. Schoonooghe, 2019, Cancers.

Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade

M. Verdonck, A. Van Parys, N. Devoogdt, 2021, Molecular therapy. Methods & clinical development.

Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells

V. Flamand, C. Heirman, K. Thielemans, 2015, Cancer Immunology Research.

Impact of lenalidomide maintenance on the immune environment of multiple myeloma patients with low tumor burden after autologous stem cell transplantation

R. Schots, K. Thielemans, J. Caers, 2018, Oncotarget.

Oncolytic Herpes Simplex Virus Type 1 Induces Immunogenic Cell Death Resulting in Maturation of BDCA-1+ Myeloid Dendritic Cells

B. Neyns, J. Aerts, K. Breckpot, 2022, International journal of molecular sciences.

The transduction pattern of IL‐12‐encoding lentiviral vectors shapes the immunological outcome

C. Heirman, K. Thielemans, C. Goyvaerts, 2015, European journal of immunology.

Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers

Marleen Keyaerts, Nick Devoogdt, David Escors, 2017, Oncotarget.

The ReNAissanCe of mRNA-based cancer therapy

C. Heirman, K. Thielemans, K. Breckpot, 2015, Expert review of vaccines.

Targeting the tumor microenvironment to enhance antitumor immune responses

C. Heirman, K. Thielemans, C. Goyvaerts, 2014, Oncotarget.

Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

N. Devoogdt, Y. De Vlaeminck, C. Goyvaerts, 2023, Theranostics.