E. Aguado

发表

Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.

P. Perrin, R. Locksley, M. Mingueneau, 2009, Immunity.

HLA-B2702 (77–83/83–77) Peptide Binds to β-Tubulin on Human NK Cells and Blocks Their Cytotoxic Capacity1

G. López-Lluch, R. Solana, E. Aguado, 2000, The Journal of Immunology.

Their Cytotoxic Capacity-Tubulin on Human NK Cells and Blocks β 77 ) Peptide Binds to − 83 / 83 − HLA-B

G. López-Lluch, R. Solana, E. Aguado, 2000 .

Influence of size and surface capping on photoluminescence and cytotoxicity of gold nanoparticles

E. Aguado, F. García-Cozar, C. Fernández-Ponce, 2018, Journal of Nanoparticle Research.

Functional expression of CD43 on human natural killer cells

M. Gallego, E. Aguado, M. Santamaria, 1999, Journal of leukocyte biology.

Altered expression of CD43-hexasaccharide isoform on peripheral T lymphocytes from HIV-infected individuals

M. Gallego, E. Aguado, J. M. Kindelán, 2001, AIDS.

The role of the adapter LAT in T cell activation and maturation

E. Aguado, M. Martínez-Florensa, 2005 .

Induction of T Helper Type 2 Immunity by a Point Mutation in the LAT Adaptor

B. Malissen, M. Malissen, Xiao-jun Guo, 2002, Science.

Role of the LAT adaptor in T-cell development and Th2 differentiation.

B. Malissen, M. Malissen, E. Aguado, 2005, Advances in immunology.

A Novel, LAT/Lck Double Deficient T Cell Subline J.CaM1.7 for Combined Analysis of Early TCR Signaling

A. Miazek, E. Aguado, I. Serrano-García, 2021, Cells.

The Type 1 Cysteinyl Leukotriene Receptor Triggers Calcium Influx and Chemotaxis in Mouse αβ- and γδ Effector T Cells1

H. Mollenkopf, S. Kaufmann, B. Malissen, 2005, The Journal of Immunology.

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation.

B. Malissen, B. Payrastre, M. Malissen, 2007, Blood.

Inhibition of CD28-mediated natural cytotoxicity by KIR2DL2 does not require p56(lck) in the NK cell line YT-Indy.

J. Coligan, F. Borrego, R. Solana, 2002, Molecular immunology.

Aggregation of MHC class I molecules on a CD8+ α β T cell clone specifically inhibits non‐antigen‐specific lysis of target cells

D. Sancho, E. Aguado, P. Aparicio, 2004 .

A Stretch of Negatively Charged Amino Acids of Linker for Activation of T-Cell Adaptor Has a Dual Role in T-Cell Antigen Receptor Intracellular Signaling

Michael Loran Dustin, A. Miazek, E. Aguado, 2018, Front. Immunol..

LAT regulates gammadelta T cell homeostasis and differentiation.

L. Xerri, B. Chetaille, B. Malissen, 2003, Nature immunology.

Platelet aggregation induced by the C‐terminal peptide of thrombospondin‐1 requires the docking protein LAT but is largely independent of αIIb/β3

B. Malissen, B. Payrastre, M. Plantavid, 2003, Journal of thrombosis and haemostasis : JTH.

Increased Protein Stability and Interleukin-2 Production of a LATG131D Variant With Possible Implications for T Cell Anergy

A. Miazek, E. Aguado, F. García-Cozar, 2020, Frontiers in Cell and Developmental Biology.

Assessment of caspase mediated degradation of linker for activation of T cells (LAT) at a single cell level.

P. Kisielow, A. Miazek, E. Aguado, 2013, Journal of immunological methods.

In vivo retrovirus-mediated gene transfer to the liver of dogs results in transient expression and induction of a cytotoxic immune response.

D. Aubert, N. Ferry, E. Aguado, 1999, Human gene therapy.

Editorial: Regulatory Mechanisms of Early Intracellular Signaling in T Lymphocytes

E. Compeer, A. Miazek, E. Aguado, 2021, Frontiers in Cell and Developmental Biology.

Non–T Cell Activation Linker (NTAL)

Naděžda Brdičková, B. Schraven, J. Špička, 2002, The Journal of experimental medicine.

LAT regulates γδ T cell homeostasis and differentiation

L. Xerri, B. Chetaille, B. Malissen, 2003, Nature Immunology.

Immune modulation by the hepatitis C virus core protein

M. Dominguez-Villar, E. Aguado, F. García-Cozar, 2017, Journal of viral hepatitis.

PARP‐2 deficiency affects the survival of CD4+CD8+ double‐positive thymocytes

J. Yélamos, V. Schreiber, J. Ménissier-de murcia, 2006, The EMBO journal.

CD4+ Primary T Cells Expressing HCV-Core Protein Upregulate Foxp3 and IL-10, Suppressing CD4 and CD8 T Cells

M. Dominguez-Villar, E. Aguado, F. García-Cozar, 2014, PloS one.

Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells.

J. Yélamos, V. Schreiber, P. Parrilla, 2008, Molecular immunology.

Serine residues in the LAT adaptor are essential for TCR‐dependent signal transduction

J. Yélamos, B. Malissen, Antonio García-Blesa, 2011, Journal of leukocyte biology.

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

Marie Malissen, Romain Roncagalli, Bernard Malissen, 2008, Nature Immunology.

Ultrastructural Localization and Molecular Associations of HCV Capsid Protein in Jurkat T Cells

W. Bloch, C. Baumann, E. Aguado, 2018, Front. Microbiol..

Identification of functional, short-lived isoform of linker for activation of T cells (LAT)

M. Majkowski, A. Miazek, E. Aguado, 2014, Genes and Immunity.

The atheroma plaque secretome stimulates the mobilization of endothelial progenitor cells ex vivo.

A. Heck, A. Altelaar, J. Bolívar, 2017, Journal of molecular and cellular cardiology.

Dynamic recruitment of the adaptor protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment

D. Olive, F. Sánchez‐Madrid, C. Langlet, 2004, Journal of Cell Science.

Mutation of the glycine residue preceding the sixth tyrosine of the LAT adaptor severely alters T cell development and activation

B. Malissen, Yinming Liang, E. Aguado, 2022, Frontiers in Immunology.

The membrane adaptor LAT is proteolytically cleaved following Fas engagement in a tyrosine phosphorylation-dependent fashion.

B. Malissen, A. Miazek, E. Aguado, 2013, The Biochemical journal.

Autistic effector T cells in mice with a point mutation in the LAT adaptor fail to respond to Listeria monocytogenes infection.

S. Kaufmann, B. Malissen, H. Mittrücker, 2005, International immunology.

Expression of Non-T Cell Activation Linker (NTAL) in Jurkat Cells Negatively Regulates TCR Signaling: Potential Role in Rheumatoid Arthritis

E. Aguado, F. Medina-Varo, I. Serrano-García, 2023, International journal of molecular sciences.

Slow phosphor-Y-LAT-ion for TCR ligand discrimination

E. Aguado, M. M. Arbulo-Echevarria, 2019, Nature Immunology.

Non‐T cell activation linker (NTAL) proteolytic cleavage as a terminator of activatory intracellular signals

A. Miazek, E. Aguado, C. Fernández-Ponce, 2016, Journal of leukocyte biology.

Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription

A. Miazek, E. Aguado, K. Marek-Bukowiec, 2016, Genes and Immunity.

Activation of T lymphocytes and the role of the adapter LAT.

E. Aguado, P. Aparicio, M. Martínez-Florensa, 2006, Transplant immunology.

A Story of Kinases and Adaptors: The Role of Lck, ZAP-70 and LAT in Switch Panel Governing T-Cell Development and Activation

E. Aguado, Inmaculada Vico-Barranco, M. M. Arbulo-Echevarria, 2023, Biology.

Serine residues in the LAT adaptor are essential for TCR‐dependent signal transduction

J. Yélamos, B. Malissen, M. Dominguez-Villar, 2011, Journal of leukocyte biology.

Raman spectroscopic study of transfected HEK293T cells

S. Sánchez‐Cortés, E. Aguado, N. Joshi, 2012 .