P. Schweizer

发表

The human cardiac K2P3.1 (TASK-1) potassium leak channel is a molecular target for the class III antiarrhythmic drug amiodarone

H. Katus, Dierk Thomas, E. Ficker, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

Cardiac K2P13.1 (THIK-1) two-pore-domain K+ channels: Pharmacological regulation and remodeling in atrial fibrillation.

H. Katus, Dierk Thomas, P. Lugenbiel, 2019, Progress in biophysics and molecular biology.

Long-term use of amiodarone before heart transplantation significantly reduces early post-transplant atrial fibrillation and is not associated with increased mortality after heart transplantation

C. Gleissner, H. Katus, L. Frankenstein, 2016, Drug design, development and therapy.

Inhibition of cardiac two-pore-domain K+ (K2P) channels--an emerging antiarrhythmic concept.

H. Katus, Dierk Thomas, C. Schmidt, 2014, European journal of pharmacology.

Herg K+ Channel-Dependent Apoptosis and Cell Cycle Arrest in Human Glioblastoma Cells

H. Katus, Dierk Thomas, P. Schweizer, 2014, PloS one.

Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine

H. Katus, Dierk Thomas, E. Ficker, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine

W. Wenzel, H. Katus, Dierk Thomas, 2011, Naunyn-Schmiedeberg's Archives of Pharmacology.

Carvedilol targets human K2P3.1 (TASK1) K+ leak channels

H. Katus, Ann-Kathrin Rahm, E. Ficker, 2011, British journal of pharmacology.

In vivo cardiac pacemaker function of differentiated human mesenchymal stem cells from adipose tissue transplanted into porcine hearts

H. Katus, U. Leimer, Dierk Thomas, 2020, World journal of stem cells.

The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease.

A. Draguhn, C. Bruehl, F. Sedaghat-Hamedani, 2019, Biochemical and biophysical research communications.

Sinus Node Disease and Cardiac Conduction Disease

P. Schweizer, 2018 .

Novel approach to discriminate left bundle branch block from nonspecific intraventricular conduction delay using pacing-induced functional left bundle branch block

H. Katus, Dierk Thomas, P. Lugenbiel, 2018, Journal of Interventional Cardiac Electrophysiology.

Fully digital data processing during cardiovascular implantable electronic device follow-up in a high-volume tertiary center

L. Uhlmann, H. Katus, Dierk Thomas, 2017, European Journal of Medical Research.

ANK2 functionally interacts with KCNH2 aggravating long QT syndrome in a double mutation carrier.

S. Heinemann, J. Haas, H. Katus, 2019, Biochemical and biophysical research communications.

Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability.

H. Katus, Dierk Thomas, P. Schweizer, 2011, Biochimica et biophysica acta.

Cloning and characterization of zebrafish K2P13.1 (THIK-1) two-pore-domain K+ channels.

H. Katus, Dierk Thomas, J. Gierten, 2019, Journal of Molecular and Cellular Cardiology.

Improved Generation of Human Induced Pluripotent Stem Cell-Derived Cardiac Pacemaker Cells Using Novel Differentiation Protocols

N. Frey, R. Rivinius, P. Schweizer, 2022, International journal of molecular sciences.

Augmentation of myocardial If dysregulates calcium homeostasis and causes adverse cardiac remodeling

A. Draguhn, C. Bruehl, R. Fink, 2019, Nature Communications.

Alternative splicing determines mRNA translation initiation and function of human K2P10.1 K+ channels

H. Katus, Dierk Thomas, Ann-Kathrin Rahm, 2011, The Journal of physiology.

Therapeutic targeting of two-pore-domain potassium (K(2P)) channels in the cardiovascular system.

H. Katus, Dierk Thomas, C. Schmidt, 2016, Clinical science.

Modulation of K2P2.1 and K2P10.1 K+ channel sensitivity to carvedilol by alternative mRNA translation initiation

H. Katus, P. Schweizer, D. Thomas, 2014, British journal of pharmacology.

Inhibition of cardiac two-pore-domain K+ (K2P) channels by the antiarrhythmic drug vernakalant--comparison with flecainide.

H. Katus, Dierk Thomas, P. Schweizer, 2014, European journal of pharmacology.

Enhancement of K2P2.1 (TREK1) background currents expressed in Xenopus oocytes by voltage-gated K+ channel β subunits.

H. Katus, Dierk Thomas, P. Schweizer, 2012, Life sciences.

Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels

H. Katus, Dierk Thomas, C. Schmidt, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Transcription profiling of HCN-channel isotypes throughout mouse cardiac development

H. Katus, Dierk Thomas, P. Schweizer, 2009, Basic Research in Cardiology.

Regulation of apoptosis in HL‐1 cardiomyocytes by phosphorylation of the receptor tyrosine kinase EphA2 and protection by lithocholic acid

H. Katus, P. Schweizer, I. Staudacher, 2012, British Journal of Pharmacology.

Biological Heart Rate Reduction Through Genetic Suppression of Gαs Protein in the Sinoatrial Node

H. Katus, Dierk Thomas, P. Lugenbiel, 2012, Journal of the American Heart Association.

Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels.

H. Katus, Dierk Thomas, J. Gierten, 2012, Biochimica et biophysica acta.

Identification and functional characterization of zebrafish K2P17.1 (TASK‐4, TALK‐2) two‐pore‐domain K+ channels

H. Katus, Dierk Thomas, J. Gierten, 2018, European journal of pharmacology.

Vernakalant activates human cardiac K(2P)17.1 background K(+) channels.

H. Katus, Dierk Thomas, E. Zitron, 2014, Biochemical and biophysical research communications.

Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure.

W. Wenzel, H. Katus, Dierk Thomas, 2014, Heart rhythm.

Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels.

H. Katus, Dierk Thomas, C. Schmidt, 2013, European journal of pharmacology.

Functional characterization of zebrafish K2P18.1 (TRESK) two-pore-domain K+ channels

H. Katus, Dierk Thomas, C. Schmidt, 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

PKC‐dependent activation of human K2P18.1 K+ channels

H. Katus, Dierk Thomas, Ann-Kathrin Rahm, 2012, British journal of pharmacology.

The symptom complex of familial sinus node dysfunction and myocardial noncompaction is associated with mutations in the HCN4 channel.

A. Draguhn, C. Bruehl, J. Haas, 2014, Journal of the American College of Cardiology.

Electrophysiological fi ndings in Fabry cardiomyopathy: mapping the maze of risk stratifi cation

A. Warth, P. Schnabel, H. Katus, 2012 .

Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure and Preserved Ejection Fraction

M. Kieser, H. Katus, N. Frey, 2022, Circulation: Heart Failure.

Obesity Cardiovascular Disease and the Failure of Public Health Education

S. Boekholdt, H. Katus, C. Bezzina, 2022 .

cAMP Sensitivity of HCN Pacemaker Channels Determines Basal Heart Rate But Is Not Critical for Autonomic Rate Control

A. Draguhn, C. Bruehl, H. Katus, 2010, Circulation. Arrhythmia and electrophysiology.

Dilation of the Aorta Ascendens Forms Part of the Clinical Spectrum of HCN4 Mutations.

A. Wilde, S. Boekholdt, H. Katus, 2016, Journal of the American College of Cardiology.

A Distinct Cardiomyopathy: HCN4 Syndrome Comprising Myocardial Noncompaction, Bradycardia, Mitral Valve Defects, and Aortic Dilation.

H. Katus, Dierk Thomas, P. Schweizer, 2017, Journal of the American College of Cardiology.

Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2.

H. Katus, Dierk Thomas, P. Schweizer, 2012, Biochemical and biophysical research communications.

Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation.

A. Draguhn, C. Bruehl, I. Schlichting, 2013, European heart journal.

Provocation of an autoimmune response to cardiac voltage-gated sodium channel NaV1.5 induces cardiac conduction defects in rats.

M. Karck, H. Katus, E. Giannitsis, 2013, Journal of the American College of Cardiology.

Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system

S. Meuth, K. Klingel, T. Budde, 2022, Cellular and Molecular Life Sciences.

Quantitative Efficacy and Fate of Mesenchymal Stromal Cells Targeted to Cardiac Sites by Radiofrequency Catheter Ablation

H. Katus, A. Seckinger, Dierk Thomas, 2020, Cell transplantation.

Cardiovascular pharmacology of K2P17.1 (TASK-4, TALK-2) two-pore-domain K+ channels

H. Katus, S. Chai, Christina Mayer, 2018, Naunyn-Schmiedeberg's Archives of Pharmacology.

Novel roles for hERG K+ channels in cell proliferation and apoptosis

H. Katus, P. Schweizer, J. Jehle, 2011, Cell Death and Disease.

Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells.

A. Draguhn, C. Bruehl, D. Hose, 2019, Life Science.

Butterfly and reverse butterfly: usefulness of a resistance band to provoke exercise-induced arrhythmias during catheter ablation in a patient refractory to pharmacological stimulation

H. Katus, Dierk Thomas, P. Lugenbiel, 2018, Clinical Research in Cardiology.

Cryoballoon pulmonary vein isolation-mediated rise of sinus rate in patients with paroxysmal atrial fibrillation

H. Katus, Dierk Thomas, P. Lugenbiel, 2020, Clinical Research in Cardiology.

The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation

H. Katus, Dierk Thomas, C. Schmidt, 2011, Vascular health and risk management.

Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation

H. Katus, Dierk Thomas, P. Schweizer, 2011, Drug design, development and therapy.

Prevalence of intracardiac thrombi under phenprocoumon, direct oral anticoagulants (dabigatran and rivaroxaban), and bridging therapy in patients with atrial fibrillation and flutter.

M. Kieser, H. Katus, D. Mereles, 2015, The American journal of cardiology.

Anti-KCNQ1 K⁺ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy.

H. Katus, Dierk Thomas, C. Schmidt, 2013, Cardiovascular research.

Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels

H. Katus, Dierk Thomas, C. Schmidt, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

I Ks current and are associated with QT interval shortening in dilated cardiomyopathy

H. Katus, Dierk Thomas, C. Schmidt, 2013 .

Atrial Fibrillation Complicated by Heart Failure Induces Distinct Remodeling of Calcium Cycling Proteins

H. Katus, Dierk Thomas, P. Lugenbiel, 2015, PloS one.

Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation

M. Borggrefe, M. Karck, H. Katus, 2015, Circulation.

Upregulation of K 2 P 3 . 1 K + Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation

M. Borggrefe, M. Karck, H. Katus, 2015 .

Current Causes Action Potential Shortening in Patients with Chronic Atrial Fibrillation

M. Borggrefe, M. Karck, H. Katus, 2015 .

German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper: impact of molecular mechanisms on clinical arrhythmia management

A. Goette, R. Wakili, J. Heijman, 2018, Clinical Research in Cardiology.

University of Birmingham German Cardiac Society Working Group on Cellular Electrophysiology state-of-the-art paper

A. Goette, R. Wakili, J. Heijman, 2018 .

Effects of β-blocker therapy on electrocardiographic and echocardiographic characteristics of left ventricular noncompaction

H. Katus, B. Meder, D. Mereles, 2015, Clinical Research in Cardiology.

Genetic suppression of Gαs protein provides rate control in atrial fibrillation

H. Katus, Dierk Thomas, P. Lugenbiel, 2012, Basic Research in Cardiology.

Mechanisms of zolpidem‐induced long QT syndrome: acute inhibition of recombinant hERG K+ channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells

H. Katus, C. Schmidt, I. Deschênes, 2013, British journal of pharmacology.

Impaired ion channel function related to a common KCNQ1 mutation - implications for risk stratification in long QT syndrome 1.

H. Katus, Dierk Thomas, P. Schweizer, 2012, Gene.

Atrial fibrillation before heart transplantation is a risk factor for post‐transplant atrial fibrillation and mortality

N. Frey, Dierk Thomas, R. Rivinius, 2021, ESC heart failure.

Antiarrhythmic gene therapy - will biologics replace catheters, drugs and devices?

H. Katus, Dierk Thomas, P. Lugenbiel, 2016, European journal of pharmacology.

Successful acute and long-term management of electrical storm in Brugada syndrome using orciprenaline and quinine/quinidine

H. Katus, Dierk Thomas, P. Schweizer, 2010, Clinical Research in Cardiology.

Efficacy, High Procedural Safety And Rapid Optimization Of Cryoballoon Atrial Fibrillation Ablation In The Hands Of A New Operator.

H. Katus, Dierk Thomas, P. Lugenbiel, 2016, Journal of atrial fibrillation.

TREK-1 (K2P2.1) K+ channels are suppressed in patients with atrial fibrillation and heart failure and provide therapeutic targets for rhythm control

C. Bruehl, M. Karck, H. Katus, 2016, Basic Research in Cardiology.

Atrial‐Radiofrequency Catheter Ablation Mediated Targeting of Mesenchymal Stromal Cells

A. Ho, H. Katus, A. Seckinger, 2007, Stem cells.

hERG: protein trafficking and potential for therapy and drug side effects.

Hugo A Katus, H. Katus, Dierk Thomas, 2010, Current opinion in drug discovery & development.

Sphingosine-1-phosphate Treatment Improves Cryopreservation Efﬁciency in Human Mesenchymal Stem Cells

Young-Hoon Kang, G. Rho, P. Schweizer, 2023 .

Role of ion channels in heart failure and channelopathies

H. Katus, Dierk Thomas, P. Lugenbiel, 2018, Biophysical Reviews.

Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

J. Utikal, A. Draguhn, H. Katus, 2017, Stem Cell Research & Therapy.

Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation".

M. Borggrefe, M. Karck, H. Katus, 2016, Circulation.

Functional characterization of zebrafish K2P18.1 (TRESK) two-pore-domain K+ channels

H. Katus, Dierk Thomas, C. Schmidt, 2014, Naunyn-Schmiedeberg's Archives of Pharmacology.

Biophysical characterization of KCNQ1 P320 mutations linked to long QT syndrome 1.

H. Katus, Dierk Thomas, C. Karle, 2010, Journal of molecular and cellular cardiology.

Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells

J. Utikal, A. Draguhn, H. Katus, 2017, Stem Cell Research & Therapy.

Epigenetic regulation of cardiac electrophysiology in atrial fibrillation: HDAC2 determines action potential duration and suppresses NRSF in cardiomyocytes

C. Bruehl, P. Most, M. Karck, 2021, Basic Research in Cardiology.

Cardiac expression and atrial fibrillation-associated remodeling of K₂p2.1 (TREK-1) K⁺ channels in a porcine model.

W. Wenzel, H. Katus, Dierk Thomas, 2014, Life sciences.

Vascular Health and Risk Management Dovepress the Pathology and Treatment of Cardiac Arrhythmias: Focus on Atrial Fibrillation

C. Schmidt, P. Schweizer, J. Kisselbach, 2022 .

The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation

C. Schmidt, P. Schweizer, J. Kisselbach, 2011 .

Cardiovascular pharmacology of K2P17.1 (TASK-4, TALK-2) two-pore-domain K+ channels

H. Katus, Christina Mayer, Dierk Thomas, 2018, Naunyn-Schmiedeberg's Archives of Pharmacology.

Enhancement of K2P2.1 (TREK1) background currents expressed in Xenopus oocytes by voltage-gated K+ channel β subunits.

H. Katus, Dierk Thomas, P. Schweizer, 2012, Life sciences.

Anti-KCNQ1 K⁺ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy.

H. Katus, Dierk Thomas, C. Schmidt, 2013, Cardiovascular research.

Chest pain, shortness of breath, and palpitations unmask an unexpected diagnosis.

A. Remppis, H. Katus, S. Aulmann, 2012, Circulation.

Role of ion channels in heart failure and channelopathies

H. Katus, Dierk Thomas, P. Lugenbiel, 2018, Biophysical Reviews.

Initial experience with robotic navigation for catheter ablation of paroxysmal and persistent atrial fibrillation.

Hugo A Katus, H. Katus, Dierk Thomas, 2012, Journal of electrocardiology.

Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability.

H. Katus, Dierk Thomas, P. Schweizer, 2011, Biochimica et biophysica acta.