K. Bachmann

发表

Examination of the Effect of Increasing Doses of Etoricoxib on Oral Methotrexate Pharmacokinetics in Patients With Rheumatoid Arthritis

T. Marbury, K. Gottesdiener, J. Schwartz, 2009, Journal of clinical pharmacology.

Lack of Pharmacokinetic Interaction between Rofecoxib and Methotrexate in Rheumatoid Arthritis Patients

J. Miller, B. Gertz, J. Redfern, 2001, Journal of clinical pharmacology.

The Potential of In Silico and In Vitro Approaches to Predict In Vivo Drug–Drug Interactions and ADMET/TOX Properties

S. Ekins, K. Bachmann, 2012 .

Inhibition constants, inhibitor concentrations and the prediction of inhibitory drug drug interactions: pitfalls, progress and promise.

K. Bachmann, Kenneth Bachmann, 2006, Current drug metabolism.

Scaling basic toxicokinetic parameters from rat to man.

K. Bachmann, D. Pardoe, D. White, 1996, Environmental health perspectives.

Development of CDD‐0102 as a selective M1 agonist for the treatment of Alzheimer's disease

C. Dockery, A. El-Assadi, E. Hassoun, 2002 .

Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.

K. Bachmann, L. Jauregui, 1993, Xenobiotica; the fate of foreign compounds in biological systems.

The Processing of the Selective M1 Agonist CDD-0102-J by Human Hepatic Drug Metabolizing Enzymes

W. Hoss, K. Bachmann, Urvi Telang, 2005, American journal of therapeutics.

Protein Binding of Coumarin Anticoagulants in Disease States

K. Bachmann, R. Shapiro, Ronald S. Shapiro, 1977, Clinical pharmacokinetics.

Human Pregnane X Receptor Antagonists and Agonists Define Molecular Requirements for Different Binding Sites

Sean Ekins, Ni Ai, Rachana Patel, 2007, Molecular Pharmacology.

An investigation of the relationship between estrogen, estrogen metabolites and blood cholesterol levels in ovariectomized rats.

K. Bachmann, D. Liu, Dongfang Liu, 1998, The Journal of pharmacology and experimental therapeutics.

Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity.

T. Sullivan, K. Bachmann, K. Miller, 1993, British journal of clinical pharmacology.

Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans.

J. Sarver, K. Bachmann, 1996, Pharmacology.

Estimating xenobiotic half-lives in humans from rat data: influence of log P.

J. Sarver, K. Bachmann, D. White, 1997, Environmental health perspectives.

Ethosuximide is primarily metabolized by CYP3A when incubated with isolated rat liver microsomes.

J. Sarver, K. Bachmann, W. Kliś, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Cytochrome P450 Enzymes and Drug—Drug Interactions: An Update on the Superfamily

Jeffrey D. Lewis, K. Bachmann, 2006 .

Serum lipids as biomarkers for therapeutic monitoring of latent tuberculosis infection

D. Menzies, A. Albanna, K. Bachmann, 2013, European Respiratory Journal.

Genotyping and Phenotyping the Cytochrome P-450 Enzymes

K. Bachmann, 2002, American journal of therapeutics.

Clinical evaluation of a noninvasive technology for the treatment of chronic joint symptoms

K. Bachmann, D. White, Kenneth M Chelucci, 2013 .

Predicting toxicokinetic parameters in humans from toxicokinetic data acquired from three small mammalian species

K. Bachmann, 1989, Journal of applied toxicology : JAT.

Effect of Montelukast on Single‐Dose Theophylline Pharmacokinetics

T. Reiss, T. Sullivan, J. Schwartz, 1998, American journal of therapeutics.

Influence of some novel N-substituted azoles and pyridines on rat hepatic CYP3A activity.

T. Rho, J. Slama, L. Sambucetti, 1998, Biochemical pharmacology.

Multiple-dose pharmacokinetics of intravenously administered cefoperazone and sulbactam when given in combination to infected, seriously ill, elderly patients

J. Schwartz, K. Bachmann, L. Jauregui, 1988, Antimicrobial Agents and Chemotherapy.

The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism.

M. Nunlee, J. Schwartz, K. Bachmann, 1990, Xenobiotica; the fate of foreign compounds in biological systems.

The suitability of carbamazepine as a single-sample probe of human mixed function oxidase activity.

J. Schwartz, K. Bachmann, L. Jauregui, 1989, Xenobiotica; the fate of foreign compounds in biological systems.

Short report: a comparative study of the interaction between antacid and H2‐receptor antagonists

K. Bachmann, K. Miller, J. Reese, 1994, Alimentary pharmacology & therapeutics.

Impact of ciprofloxacin on theophylline clearance and steady-state concentrations in serum

J. Lettieri, J. Schwartz, K. Bachmann, 1988, Antimicrobial Agents and Chemotherapy.

The influence of anesthetic agents on rat hepatic cytochromes P450 in vivo.

K. Bachmann, J. Loch, J. Potter, 1995, Pharmacology.

A Controlled Comparison of Continuous Ranitidine and Intermittent Famotidine Infusions on Gastric pH

T. Sullivan, K. Bachmann, L. Jauregui, 1993, Journal of clinical pharmacology.

Warfarin Elimination and Responsiveness in Patients with Renal Dysfunction

K. Bachmann, R. Shapiro, James Mackiewicz, 1977, Journal of clinical pharmacology.

Dispositional and pharmacodynamic characteristics of brodifacoum in warfarin-sensitive rats.

T. Sullivan, K. Bachmann, 1983, Pharmacology.

Influence of a 3-day regimen of azithromycin on the disposition kinetics of cyclosporine A in stable renal transplant patients.

K. Bachmann, K. Thakker, R. Chandra, 2003, Pharmacological research.

The Influence of Dirithromycin on the Pharmacokinetics of Cyclosporine in Healthy Subjects and in Renal Transplant Patients.

T. Sullivan, K. Bachmann, G. Sides, 1995, American journal of therapeutics.

Steady‐State Pharmacokinetics of Theophylline in COPD Patients Treated With Dirithromycin

T. Sullivan, K. Bachmann, G. Sides, 1993, Journal of clinical pharmacology.

The effect of erythromycin on the disposition kinetics of warfarin.

J. Schwartz, K. Bachmann, R. Forney, 1984, Pharmacology.

Phenylbutazone and warfarin : aspects of their interaction in the dog /

K. Bachmann, 1973 .

Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework.

Edward J Calabrese, Thomas B Knudsen, Jim E Riviere, 2007, Toxicology and applied pharmacology.

ImpactofCiprofloxacin on Theophylline Clearance andSteady-State Concentrations inSerum

K. Bachmann, 1988 .

Convenient synthesis of 6-nor-9,10-dihydrolysergic acid methyl ester.

A. Crider, K. Bachmann, A. Rawat, 1981, Journal of Pharmacy and Science.

CONVENIENT SYNTHESIS OF 6‐NOR‐9,10‐DIHYDROLYSERGIC ACID METHYL ESTER

A. Crider, K. Bachmann, A. Rawat, 1982 .

Failure of Ceftibuten to Alter Single Dose Theophylline Clearance

M. Nunlee, J. Schwartz, K. Bachmann, 1990, Journal of clinical pharmacology.

Chapter 8 – Drug Metabolism

K. Bachmann, 2009 .

Drug interactions of H2-receptor antagonists.

T. Sullivan, K. Bachmann, K. Miller, 1994, Scandinavian journal of gastroenterology. Supplement.

Pharmacology: Principles and Practice

M. Hacker, K. Bachmann, Kenneth Bachmann, 2008 .

PXR and the regulation of apoA1 and HDL-cholesterol in rodents.

Sean Ekins, S. Ekins, Hiral S. Patel, 2004, Pharmacological research.

Exercise training does not alter cytochrome P-450 content and microsomal metabolism.

M. Flynn, K. Bachmann, F. Andres, 1994, Medicine and science in sports and exercise.

Computational Discovery of Novel Low Micromolar Human Pregnane X Receptor Antagonists

Sean Ekins, Ni Ai, Vladyslav Kholodovych, 2008, Molecular Pharmacology.

Accuracy of Two Equations in Determining Normalized Phenytoin Concentrations

J. D. Robinson, K. Bachmann, L. S. Mauro, 1989, DICP : the annals of pharmacotherapy.

Differential Kinetics of Phenytoin in Elderly Patients

K. Bachmann, Robert J. Jr Belloto, Robert J. Jr Belloto, 1999, Drugs & aging.

In vivo evidence that theophylline is metabolized principally by CYP1A in rats.

G. Sanyal, R. Schiavone, K. Bachmann, 1993, Pharmacology.

Provision of Drug Information to Patients by Pharmacists: The Impact of the Omnibus Budget Reconciliation Act of 1990 a Decade Later

K. Bachmann, R. J. Belloto, Robin A Schatz, 2003, American journal of therapeutics.

The effects of cobalt chloride, SKF-525A, and N-(3,5-dichlorophenyl)succinimide on in vivo hepatic mixed function oxidase activity as determined by single-sample plasma clearances.

G. Rankin, K. Bachmann, M. Madhira, 1992, Xenobiotica; the fate of foreign compounds in biological systems.

Use of Plasma Unbound Drug Concentrations in Adjusting Phenytoin Doses

K. Bachmann, R. Forney, K. Voeller, 1984, Therapeutic Drug Monitoring.

Estimating the clearance of amylobarbitone from a single plasma measurement.

K. Bachmann, 1987, British journal of clinical pharmacology.

A nationwide survey of physician office visits found that inappropriate antibiotic prescriptions were issued for bacterial respiratory tract infections in ambulatory patients.

Xuming He, Steven J Martin, Ying Wei, 2005, Journal of clinical epidemiology.

Inappropriate prescriptions for the aging population of the United States: an analysis of the National Ambulatory Medical Care Survey, 1997

Xuming He, Randi Chen, Boji Huang, 2002, Pharmacoepidemiology and drug safety.

A Comprehensive in Vitro and in Silico Analysis of Antibiotics That Activate Pregnane X Receptor and Induce CYP3A4 in Liver and Intestine

Sean Ekins, Aarati R. Ranade, S. Ekins, 2008, Drug Metabolism and Disposition.

A possible role for cyanate in the albumin binding defect of uremia.

K. Bachmann, M. Valentovic, R. Shapiro, 1980, Biochemical pharmacology.

The use of single sample clearance estimates to probe hepatic drug metabolism in rats. I.

J. Schwartz, K. Bachmann, D. Jahn, 1988, Xenobiotica; the fate of foreign compounds in biological systems.

The use of single-sample clearance estimates to probe hepatic drug metabolism in rats. IV. A model for possible application to phenotyping xenobiotic influences on human drug metabolism.

K. Bachmann, 1989, Xenobiotica; the fate of foreign compounds in biological systems.

Predicting Inhibitory Drug—Drug Interactions and Evaluating Drug Interaction Reports Using Inhibition Constants

Jeffrey D. Lewis, K. Bachmann, Kenneth A Bachmann, 2005, The Annals of pharmacotherapy.

Use of limited laboratory-acquired therapeutic drug monitoring data in determining individualized drug requirements.

K. Bachmann, R. Forney, G. Gronau, 1987, Annals of clinical and laboratory science.

Smoking and warfarin disposition

T. Sullivan, K. Bachmann, R. Shapiro, 1979, Clinical pharmacology and therapeutics.

Changes in the Steady‐State Pharmacokinetics of Theophylline During Treatment with Dirithromycin

K. Desante, K. Bachmann, G. Sides, 1990, Journal of clinical pharmacology.

A Comprehensive in vitro and in silico Analysis of Antibiotics that Activate PXR and Induce CYP3A4 in Liver and Intestine

Aarati R. Ranade, S. Ekins, S. Strom, 2008 .

Inability of ibuprofen to alter single dose phenytoin disposition.

T. Sullivan, J. Schwartz, K. Bachmann, 1986, British journal of clinical pharmacology.

Phenytoin as a probe of drug metabolism. Predicting clearance with a salivary sample.

J. Schwartz, K. Bachmann, R. Forney, 1985, Pharmacology.

Monitoring phenytoin in salivary and plasma ultrafiltrates of pediatric patients.

K. Bachmann, R. Forney, K. Voeller, 1983, Therapeutic drug monitoring.

An Evaluation of the Dose‐Dependent Inhibition of CYP1A2 by Rofecoxib Using Theophylline as a CYP1A2 Probe

Patrick J Larson, J. Schwartz, N. Agrawal, 2003, Journal of clinical pharmacology.

Theophylline kinetics: dose dependency and single sample prediction of clearance.

J. Schwartz, K. Bachmann, R. Forney, 1985, Pharmacology.

Predicting the ciprofloxacin-theophylline interaction from single plasma theophylline measurements.

J. Schwartz, K. Bachmann, L. Jauregui, 1988, British journal of clinical pharmacology.

Phenylbutazone‐warfarin interaction in the dog

K. Bachmann, A. M. BURKMAN, 1975, The Journal of pharmacy and pharmacology.

Influence of 3,4-benzo(a)pyrene on warfarin hypoprothrombinemia and disposition in the rat.

K. Bachmann, J. Tarloff, 1977, Toxicology and applied pharmacology.

Cyclooxygenase‐2 inhibition by rofecoxib reverses naturally occurring fever in humans

K. Grasing, B. Gertz, S. Adcock, 1999, Clinical pharmacology and therapeutics.

Drug–Drug Interactions with an Emphasis on Drug Metabolism and Transport

K. Bachmann, 2009 .

Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes

N. Peng, J. Sarver, K. Bachmann, 2003, Xenobiotica; the fate of foreign compounds in biological systems.

Controlled Study of the Putative Interaction Between Famotidine and Theophylline in Patients with Chronic Obstructive Pulmonary Disease

K C Yeh, T. Sullivan, J. Schwartz, 1995, Journal of clinical pharmacology.

Impact of cefaclor on the pharmacokinetics of theophylline.

J. Schwartz, K. Bachmann, R. Forney, 1986, Therapeutic Drug Monitoring.

The use of in vitro methods to predict in vivo pharmacokinetics and drug interactions.

K A Bachmann, R Ghosh, K. Bachmann, 2001, Current drug metabolism.

Comparative Investigation of the Influence of Nizatidine, Ranitidine, and Cimetidine on the Steady‐State Pharmacokinetics of Theophylline in COPD Patients

K. Bachmann, L. S. Mauro, Timothy Sullivan, 1992, Journal of clinical pharmacology.

Glossary and tutorial of xenobiotic metabolism terms used during small molecule drug discovery and development (IUPAC Technical Report)

N. Bodor, S. Wrighton, H. Masumoto, 2021, Pure and Applied Chemistry.

Influence of renal dysfunction on warfarin plasma protein binding.

K. Bachmann, J. Mackiewicz, R. Shapiro, 1976, Journal of clinical pharmacology.

Examination of the Effect of Increasing Doses of Etoricoxib on Oral Methotrexate Pharmacokinetics in Patients With Rheumatoid Arthritis

T. Marbury, K. Gottesdiener, N. Agrawal, 2009, Journal of clinical pharmacology.

Drug-Drug Interactions and the Cytochromes P450

B. Ring, S. Wrighton, K. Bachmann, 2003 .

A STUDY OF THE INTERACTION BETWEEN DIRITHROMYCIN AND ASTEMIZOLE IN HEALTHY ADULTS

K. Bachmann, T. Sullivan, K. Miller, 1997, American journal of therapeutics.

Contribution of cyanate to the albumin binding defect of uremia.

K. Bachmann, M. Valentovic, R. Shapiro, 1981, Biochemical pharmacology.

Chapter 8 – Drug Metabolism

K. Bachmann, 2009 .