E. Chan

发表

Regulation of metalloproteinases and NF‐κB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA

Beth Apsel, S. Abramson, R. Clancy, 2004, British journal of pharmacology.

Cyclooxygenase-2-Derived E Prostaglandins Down-Regulate Matrix Metalloproteinase-1 Expression in Fibroblast-Like Synoviocytes via Inhibition of Extracellular Signal-Regulated Kinase Activation 1

Beth Apsel, S. Abramson, J. Greenberg, 2003, The Journal of Immunology.

Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages.

B. Cronstein, K. Anwar, Hongwei H Zhang, 2008, Arthritis and rheumatism.

Methotrexate in Atherogenesis and Cholesterol Metabolism

E. Coomes, A. Reiss, E. Chan, 2011, Cholesterol.

Extracellular generation of adenosine by the ectonucleotidases CD39 and CD73 promotes dermal fibrosis.

L. Chiriboga, B. Cronstein, S. Robson, 2013, The American journal of pathology.

A BRIEF COMMUNICATION

B. Cronstein, J. Merrill, K. Anwar, 2009, Experimental biology and medicine.

A BRIEF COMMUNICATION

B. Cronstein, J. Merrill, K. Anwar, 2009, Experimental biology and medicine.

Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3

B. Cronstein, A. Mediero, E. Chan, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

90 – Immunomodulating pharmaceuticals

B. Cronstein, E. Chan, Stephen Oliver, 2008 .

Atheroprotective Effects of Methotrexate on Reverse Cholesterol Transport Proteins and Foam Cell Transformation in THP-1 Human Monocytes/Macrophages

K. Anwar, S. Carsons, A. Reiss, 2011 .

Adenosine A2A Receptor Occupancy Stimulates Collagen Expression by Hepatic Stellate Cells via Pathways Involving Protein Kinase A, Src, and Extracellular Signal-Regulated Kinases 1/2 Signaling Cascade or p38 Mitogen-Activated Protein Kinase Signaling Pathway

B. Cronstein, E. Chan, J. Che, 2007, Molecular Pharmacology.

Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.

J. F. Chen, B. Cronstein, M. Schwarzschild, 2006, Arthritis and rheumatism.

Methotrexate—how does it really work?

B. Cronstein, E. Chan, Edwin S. L. Chan, 2010, Nature Reviews Rheumatology.

Adenosine in fibrosis

B. Cronstein, E. Chan, Edwin S. L. Chan, 2010, Modern rheumatology.

Adenosine A2A Receptor Blockade or Deletion Diminishes Fibrocyte Accumulation in the Skin in a Murine Model of Scleroderma, Bleomycin-induced Fibrosis

B. Cronstein, E. Chan, P. Fernández, 2008, Inflammation.

The mechanisms of methotrexate’s action in the treatment of inflammatory disease

B. Cronstein, E. Chan, Edwin S. L. Chan, 2000 .

Neutrophils in Vasculitis

B. Cronstein, E. Chan, Edwin S. L. Chan, 2000 .

Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism

B. Cronstein, E. Chan, M. Trojanowska, 2013, Arthritis Research & Therapy.

Mechanisms of action of methotrexate.

B. Cronstein, E. Chan, 2013, Bulletin of the Hospital for Joint Disease.

Adenosine in inflammatory joint diseases

B. Cronstein, E. Chan, P. Fernández, 2007, Purinergic Signalling.

Molecular Pathogenesis of Skin Fibrosis: Insight from Animal Models

E. Chan, G. Smith, Edwin S. L. Chan, 2010, Current rheumatology reports.

Cholesterol 27-Hydroxylase but Not Apolipoprotein apoE Contributes to A2A Adenosine Receptor Stimulated Reverse Cholesterol Transport

E. Fisher, B. Cronstein, Saj Parathath, 2012, Inflammation.

Methotrexate in rheumatoid arthritis

B. Cronstein, E. Chan, P. Fernández, 2007, Expert review of clinical immunology.

Molecular action of methotrexate in inflammatory diseases

B. Cronstein, E. Chan, Edwin S. L. Chan, 2002, Arthritis research.

Rheumatoid Arthritis Synovial Fibroblasts Matrix Metalloproteinase Secretion from -Stimulated a Annexin-1 Mediates TNF-Abramson

S. Abramson, M. Attur, M. Pillinger, 2008 .

Adenosine A2A receptors play a role in the pathogenesis of hepatic cirrhosis

S. Friedman, H. Yee, B. Cronstein, 2006, British journal of pharmacology.

Ecto‐5′‐nucleotidase (CD73) ‐mediated extracellular adenosine production plays a critical role in hepatic fibrosis

L. Chiriboga, H. Yee, B. Cronstein, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Protein isoprenylation regulates secretion of matrix metalloproteinase 1 from rheumatoid synovial fibroblasts: effects of statins and farnesyl and geranylgeranyl transferase inhibitors.

S. Abramson, M. Attur, M. Pillinger, 2007, Arthritis and rheumatism.

Adenosine A 2 A Receptor Occupancy Stimulates Collagen Expression by Hepatic Stellate Cells via Pathways Involving Protein Kinase A , Src , and Extracellular Signal-Regulated Kinases 1 / 2 Signaling Cascade or p 38 Mitogen-Activated Protein Kinase Signaling Pathway

B. Cronstein, E. Chan, J. Che, 2007 .

Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer’s disease

M. Leon, J. Ghiso, A. Reiss, 2004, Neurobiology of Aging.

Disruption of Cholesterol Efflux by Coxib Medications and Inflammatory Processes

K. Anwar, A. Reiss, E. Chan, 2009, Journal of Investigative Medicine.

Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular risk

L. Ragolia, M. Pillinger, Hongwei H Zhang, 2007, Arthritis Research & Therapy.

Ecto-5′-Nucleotidase (Cd73)-Mediated Extracellular Adenosine Production Plays a Critical Role in Hepatic Fibrosis

L. Chiriboga, H. Yee, B. Cronstein, 2008, Nucleosides, nucleotides & nucleic acids.

Adenosine A2A receptor occupancy stimulates expression of proteins involved in reverse cholesterol transport and inhibits foam cell formation in macrophages

B. Cronstein, A. Reiss, E. Chan, 2004, Journal of leukocyte biology.

Plasma from systemic lupus patients compromises cholesterol homeostasis: a potential mechanism linking autoimmunity to atherosclerotic cardiovascular disease

B. Cronstein, J. Merrill, K. Anwar, 2010, Rheumatology International.

A2A adenosine receptor stimulation decreases foam cell formation by enhancing ABCA1‐dependent cholesterol efflux

E. Fisher, B. Cronstein, Saj Parathath, 2010, Journal of leukocyte biology.

Interferon-gamma impedes reverse cholesterol transport and promotes foam cell transformation in THP-1 human monocytes/macrophages.

B. Cronstein, A. Reiss, E. Chan, 2004, Medical science monitor : international medical journal of experimental and clinical research.

Immune complexes and IFN-gamma decrease cholesterol 27-hydroxylase in human arterial endothelium and macrophages.

B. Cronstein, A. Reiss, S. Malhotra, 2001, Journal of lipid research.

Pharmacological blockade of A2A receptors prevents dermal fibrosis in a model of elevated tissue adenosine.

L. Chiriboga, B. Cronstein, M. Blackburn, 2008, The American journal of pathology.