Zhen Ren

发表

The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.

Lei Guo, B. Ning, J. Xuan, 2016, Toxicology letters.

LINGO-1 regulates Wnt5a signaling during neural stem and progenitor cell differentiation by modulating miR-15b-3p levels

J. Qin, Zhen Ren, Chenguang Zhao, 2021, Stem cell research & therapy.

Methods for Establishing and Using a Stable Cell Line Expressing Both Gaussia Luciferase and Firefly Luciferase to Screen for Endoplasmic Reticulum Stress.

Lei Guo, Zhen Ren, Si Chen, 2020, Methods in molecular biology.

The role of hepatic cytochrome P450s in the cytotoxicity of sertraline

Lei Guo, N. Mei, B. Ning, 2020, Archives of Toxicology.

A mechanism of perhexiline's cytotoxicity in hepatic cells involves endoplasmic reticulum stress and p38 signaling pathway.

Lei Guo, Zhen Ren, Si Chen, 2020, Chemico-biological interactions.

Calcimimetic compound NPS R-467 protects against chronic cadmium-induced mouse kidney injury by restoring autophagy process.

Jie Gu, Yang Zhou, H. Shi, 2019, Ecotoxicology and environmental safety.

D-β-hydroxybutyrate inhibits microglial activation in a cell activation model in vitro

Xudong Xu, J. Tu, Zhen Ren, 2011 .

Cadmium induces triglyceride levels via microsomal triglyceride transfer protein (MTTP) accumulation caused by lysosomal deacidification regulated by endoplasmic reticulum (ER) Ca2+ homeostasis.

Jie Gu, Yang Zhou, H. Shi, 2021, Chemico-biological interactions.

Dietary cadmium exposure causes elevation of blood ApoE with triglyceride level in mice

Yang Zhou, H. Shi, J. Gu, 2020, BioMetals.

Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity.

Lei Guo, N. Mei, B. Ning, 2021, Journal of environmental science and health. Part C, Toxicology and carcinogenesis.

Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism.

Jie Gu, H. Shi, Junlin Liu, 2022, Ecotoxicology and environmental safety.

Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review.

W. Tong, Lei Guo, Joshua Xu, 2022, Regulatory toxicology and pharmacology : RTP.

Review of Ginkgo biloba-induced toxicity, from experimental studies to human case reports

Lei Guo, N. Mei, Xiaoqing Guo, 2017, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Morroniside protects OLN-93 cells against H2O2-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities

Jianguo Hu, Zhen Ren, Fengzhi Li, 2021, Cell cycle.

MicroRNA hsa‐miR‐370‐3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation

Tieliu Shi, W. Tong, Lei Guo, 2017, Biochemical pharmacology.

Long non‐coding RNA FAM66C is associated with clinical progression and promotes cell proliferation by inhibiting proteasome pathway in prostate cancer

Jie Gu, H. Shi, Zhen Ren, 2020, Cell biochemistry and function.

Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells.

Leming Shi, Lei Guo, B. Ning, 2017, Toxicology.

N-Myc downstream-regulated gene 2 restrains glycolysis and glutaminolysis in clear cell renal cell carcinoma.

Jianlin Yuan, Zhen Ren, Bao Wang, 2017, Oncology letters.

Mitochondrial dysfunction induced by leflunomide and its active metabolite.

Leming Shi, Lei Guo, T. Qing, 2018, Toxicology.

ADAM17 promotes cell migration and invasion through the integrin &bgr;1 pathway in hepatocellular carcinoma

Guo-Dong Wang, B. Meng, Zhen Ren, 2018, Experimental cell research.

Nephrotoxicity Profile of Cadmium Revealed by Proteomics in Mouse Kidney

Jie Gu, Yang Zhou, H. Shi, 2020, Biological Trace Element Research.

MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes.

B. Ning, Dianke Yu, Yongli Guo, 2016, Biochemical pharmacology.

Using a Lentivirus-Based Inducible RNAi Vector to Silence a Gene.

Lei Guo, N. Mei, B. Ning, 2020, Methods in molecular biology.

DNA damage‐induced apoptosis and mitogen‐activated protein kinase pathway contribute to the toxicity of dronedarone in hepatic cells

Lei Guo, B. Ning, Dianke Yu, 2018, Environmental and molecular mutagenesis.

Intratumor injection of oncolytic adenovirus expressing HSP70 prolonged survival in melanoma B16 bearing mice by enhanced immune response

Q. Lu, Hong-Zhuan Chen, M. Liang, 2008, Cancer biology & therapy.

ROS generation and JNK activation contribute to 4-methoxy-TEMPO-induced cytotoxicity, autophagy, and DNA damage in HepG2 cells

Lei Guo, N. Mei, Xiaoqing Guo, 2018, Archives of Toxicology.

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

W. Xiao, Tieliu Shi, Leming Shi, 2018, Archives of Toxicology.

A systematic evaluation of microRNAs in regulating human hepatic CYP2E1

W. Tong, Lei Guo, B. Ning, 2017, Biochemical pharmacology.

Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells.

Lei Guo, Jie Zhang, Albert P. Li, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Study of the roles of cytochrome P450 (CYPs) in the metabolism and cytotoxicity of perhexiline

Lei Guo, Feng Li, Zhen Ren, 2022, Archives of Toxicology.

Mitochondrial dysfunction and apoptosis underlie the hepatotoxicity of perhexiline.

Lei Guo, B. Ning, Xiaoqing Guo, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Conditionally replicative adenovirus vector carrying TRAIL gene for enhanced oncolysis of human hepatocellular carcinoma.

Q. Lu, M. Liang, X. Ye, 2005, International journal of molecular medicine.

The expression, induction and pharmacological activity of CYP1A2 are post‐transcriptionally regulated by microRNA hsa‐miR‐132–5p

W. Tong, Lei Guo, N. Mei, 2017, Biochemical pharmacology.

Activation of the Nrf2 signaling pathway in usnic acid-induced toxicity in HepG2 cells

Leming Shi, Lei Guo, N. Mei, 2017, Archives of Toxicology.