C. Goulbourne

发表

Hepatic Phospholipidosis Is Associated with Altered Hepatobiliary Function as Assessed by Gadoxetate Dynamic Contrast–enhanced Magnetic Resonance Imaging

S. Lenhard, Richard T. Miller, L. Webster, 2016, Toxicologic pathology.

A new monoclonal antibody, 4-1a, that binds to the amino terminus of human lipoprotein lipase.

S. Young, A. Beigneux, L. Fong, 2014, Biochimica et biophysica acta.

High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis[S]

S. Young, A. Beigneux, C. Grovenor, 2014, Journal of Lipid Research.

ABCG1 regulates pulmonary surfactant metabolism in mice and men[S]

D. Merriott, D. Ford, Á. Baldán, 2017, Journal of Lipid Research.

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

R. Nixon, C. Bleiwas, C. Bouchet-Marquis, 2022, Nature Neuroscience.

Reciprocal Metabolic Perturbations in the Adipose Tissue and Liver of GPIHBP1-Deficient Mice

S. Young, S. Watkins, P. Tontonoz, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1.

S. Young, A. Beigneux, Brandon S. J. Davies, 2012, Human molecular genetics.

Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease.

J. Smiley, R. Nixon, Ju-Hyun Lee, 2020, Cell reports.

Glycosylphosphatidylinositol‐anchored high‐density lipoprotein‐binding protein 1 and the intravascular processing of triglyceride‐rich lipoproteins

S. Young, A. Beigneux, L. Fong, 2012, Journal of internal medicine.

An Absence of Nuclear Lamins in Keratinocytes Leads to Ichthyosis, Defective Epidermal Barrier Function, and Intrusion of Nuclear Membranes and Endoplasmic Reticulum into the Nuclear Chromatin

S. Young, L. Fong, H. Herrmann, 2014, Molecular and Cellular Biology.

The mitochondrial calcium uniporter promotes arrhythmias caused by high-fat diet

E. Homan, J. Morrow, E. Wan, 2021, Scientific Reports.

Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency

Yufeng Shen, D. Egli, J. Gromada, 2022, Communications Biology.

HNF1A deficiency causes reduced calcium levels, accumulation of abnormal insulin granules and uncoupled insulin to C-peptide secretion in a stem cell model of MODY3

Yufeng Shen, D. Egli, J. Gromada, 2021 .

Equivalent binding of wild-type lipoprotein lipase (LPL) and S447X-LPL to GPIHBP1, the endothelial cell LPL transporter.

S. Young, A. Beigneux, L. Fong, 2014, Biochimica et biophysica acta.

Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca2+ efflux and disrupted by PSEN1 loss of function

R. Nixon, P. Lie, C. Goulbourne, 2022, Science advances.

Wolframin is a novel regulator of tau pathology and neurodegeneration

L. Honig, F. Urano, J. Kuret, 2022, Acta Neuropathologica.

Autophagy is a novel pathway for neurofilament protein degradation in vivo

R. Nixon, C. Goulbourne, Ju-Hyun Lee, 2022, Autophagy.

Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues

Yohan Kim, Pasquale D’Acunzo, E. Levy, 2022, Nature Protocols.

Sex Differentially Alters Secretion of Brain Extracellular Vesicles During Aging: A Potential Mechanism for Maintaining Brain Homeostasis

Yohan Kim, Pasquale D’Acunzo, E. Levy, 2022, Neurochemical Research.

Numb is required for optimal contraction of skeletal muscle

R. De Gasperi, A. Raczkowski, Z. Graham, 2021, bioRxiv.

Cocaine Modulates the Neuronal Endosomal System and Extracellular Vesicles in a Sex-Dependent Manner

H. Sershen, A. Hashim, Pasquale D’Acunzo, 2022, Neurochemical Research.

Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration

P. D. de Jong, Y. Yoshinaga, S. Young, 2013, Proceedings of the National Academy of Sciences.

The nucleoplasmic reticulum: form and function.

D. Vaux, C. Goulbourne, A. Malhas, 2011, Trends in cell biology.

Human stem cell model of HNF1A deficiency shows uncoupled insulin to C-peptide secretion with accumulation of abnormal insulin granules

W. Chung, Yufeng Shen, D. Egli, 2021, bioRxiv.

Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome

Yohan Kim, H. Erdjument-Bromage, Pasquale D’Acunzo, 2021, Science Advances.

P62 accumulates through neuroanatomical circuits in response to tauopathy propagation

M. Millan, K. Duff, C. Goulbourne, 2021, Acta Neuropathologica Communications.

Cocaine perturbs mitovesicle biology in the brain

H. Sershen, A. Hashim, H. Erdjument-Bromage, 2023, Journal of extracellular vesicles.

Study of molecular dynamics using fluorescently tagged molecules in live cells

D. Vaux, H. Doolittle, C. Goulbourne, 2010 .

Enhanced generation of intraluminal vesicles in neuronal late endosomes in the brain of a Down syndrome mouse model with endosomal dysfunction

Pasquale D’Acunzo, E. Levy, M. Pawlik, 2019, Developmental neurobiology.

Apolipoprotein E4 genotype compromises brain exosome production

P. Mathews, S. Ginsberg, M. Alldred, 2018, Brain : a journal of neurology.

HIV Protease Inhibitors Inhibit FACE1/ZMPSTE24: A Mechanism for Acquired Lipodystrophy in Patients on Highly Active Anti Retroviral Therapy?

D. Vaux, C. Goulbourne, 2013 .

HIV protease inhibitors inhibit FACE1/ZMPSTE24: a mechanism for acquired lipodystrophy in patients on highly active antiretroviral therapy?

D. Vaux, C. Goulbourne, 2010, Biochemical Society transactions.

The induction of a nucleoplasmic reticulum by prelamin A accumulation requires CTP:phosphocholine cytidylyltransferase-α

D. Vaux, C. Goulbourne, A. Malhas, 2011, Journal of Cell Science.

Palmoplantar keratoderma along with neuromuscular and metabolic phenotypes in Slurp1-deficient mice

S. Young, P. Tontonoz, A. Beigneux, 2014, The Journal of investigative dermatology.

The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries.

S. Young, A. Hoenger, J. Esko, 2014, Cell metabolism.

Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons.

R. Nixon, P. Lie, P. Mohan, 2021, Cell reports.

IDOL Stimulates Clathrin-Independent Endocytosis and Multivesicular Body-Mediated Lysosomal Degradation of the Low-Density Lipoprotein Receptor

S. Young, A. Ting, P. Pilch, 2013, Molecular and Cellular Biology.

Assessing mechanisms of GPIHBP1 and lipoprotein lipase movement across endothelial cells[S]

S. Young, A. Beigneux, Brandon S. J. Davies, 2012, Journal of Lipid Research.

Combined metabolomic and transcriptomic profiling approaches reveal the cardiac response to high-fat diet

J. Morrow, R. Bauer, Jianting Shi, 2022, iScience.

Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques.

A. Harris, S. Young, D. Ferguson, 2014, Methods.