Dounia Le Guillou

发表

Drug-induced hepatic steatosis in absence of severe mitochondrial dysfunction in HepaRG cells: proof of multiple mechanism-based toxicity

B. Fromenty, Simon Bucher, K. Begriche, 2020, Cell Biology and Toxicology.

A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen.

Mitchell R. McGill, H. Jaeschke, B. Fromenty, 2016, Toxicology and applied pharmacology.

Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure

D. Zalko, B. Fromenty, M. Robin, 2017, Environmental toxicology.

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo

D. Lagadic-Gossmann, B. Fromenty, C. Coulouarn, 2018, Scientific Reports.

Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure

D. Lagadic-Gossmann, B. Fromenty, Simon Bucher, 2018, Oxidative medicine and cellular longevity.

The Role of STING in Liver Injury Is Both Stimulus- and Time-Dependent

J. Maher, Dounia Le Guillou, Caroline C. Duwaerts, 2022, Nutrients.

Drug-Induced Alterations of Mitochondrial DNA Homeostasis in Steatotic and Nonsteatotic HepaRG Cells

G. Labbe, B. Fromenty, A. Lombès, 2018, The Journal of Pharmacology and Experimental Therapeutics.

Drug-induced liver injury in obesity and nonalcoholic fatty liver disease.

B. Fromenty, K. Begriche, Julien Allard, 2019, Advances in pharmacology.

iPSC-derived hepatocytes from patients with nonalcoholic fatty liver disease display a disease-specific gene expression profile.

J. Maher, H. Willenbring, Dounia Le Guillou, 2021, Gastroenterology.

Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.

B. Fromenty, C. Coulouarn, S. Anthérieu, 2014, Toxicology and applied pharmacology.

Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo

D. Lagadic-Gossmann, B. Fromenty, C. Coulouarn, 2018, Scientific Reports.

Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages

E. Hsiao, J. Maher, H. Willenbring, 2023, Nature communications.

Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate‐treated hepatocyte and stellate cell

V. Lagente, D. Glaise, S. Dutertre, 2018, Journal of cellular physiology.

Induced Pluripotent Stem Cell–derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile

J. Maher, H. Willenbring, Dounia Le Guillou, 2021, Gastroenterology.

Cellular stress in the pathogenesis of nonalcoholic steatohepatitis and liver fibrosis

Dounia Le Guillou, Sachin Sharma, Jennifer Y Chen, 2023, Nature Reviews Gastroenterology & Hepatology.

Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice.

B. Fromenty, C. Coulouarn, S. Anthérieu, 2014, Toxicology and applied pharmacology.