W. Westerink

发表

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.

W. Schoonen, Willem G E J Schoonen, Walter M A Westerink, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development.

W. Schoonen, Willem G E J Schoonen, Walter M A Westerink, 2010, Mutation research.

High‐Throughput Toxicity Testing in Drug Development: Aims, Strategies, and Novel Trends

W. Schoonen, W. Westerink, F. M. V. D. Water, 2013 .

Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition

W. Schoonen, W. Westerink, J. Stevenson, 2008, Archives of Toxicology.

The development of improved and new in vitro assays for detecting the genotoxic and non-genotoxic carcinogenic potential of chemicals in the discovery phase of drug development

W. Westerink, 2011 .

Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents.

E. Débiton, J. D. de Roos, W. Schoonen, 2005, Toxicology in vitro : an international journal published in association with BIBRA.

Safety evaluation of rebaudioside A produced by fermentation.

Lauren M. Staska, W. Westerink, Hiromi Hosako, 2016, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cytotoxic effects of 109 reference compounds on rat H4IIE and human HepG2 hepatocytes. III: Mechanistic assays on oxygen consumption with MitoXpress and NAD(P)H production with Alamar Blue™.

W. Schoonen, W. Westerink, G. Horbach, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

High-throughput screening for analysis of in vitro toxicity.

W. Schoonen, Willem G E J Schoonen, Walter M A Westerink, 2009, EXS.

Cytotoxic effects of 100 reference compounds on Hep G2 and HeLa cells and of 60 compounds on ECC-1 and CHO cells. I mechanistic assays on ROS, glutathione depletion and calcein uptake.

E. Débiton, J. D. de Roos, W. Schoonen, 2005, Toxicology in vitro : an international journal published in association with BIBRA.

Phase II enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.

W. Schoonen, Willem G E J Schoonen, Walter M A Westerink, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Genotoxicity and Carcinogenicity: Regulatory and Novel Test Methods

W. Schoonen, W. Westerink, G. Horbach, 2013 .

Evaluation of the Vitotox and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development.

Annick Lauwers, A. Lauwers, W. Schoonen, 2009, Mutation research.

Development and validation of a high-content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells.

T. Schirris, W. Schoonen, Willem G E J Schoonen, 2011, Mutation research.

REACH alternative testing strategy for skin sensitization in practice: Fact or fiction?

W. Westerink, J. Rijk, J. Paulussen, 2019, Regulatory toxicology and pharmacology : RTP.

CYP1A induction and species differences between human HepG2 and rat H4IIE cells

W. Schoonen, W. Westerink, J. C. Stevenson, 2007 .

The kinetic Direct Peptide Reactivity Assay (kDPRA): Intra- and inter-laboratory reproducibility in a seven-laboratory ring trial.

S. Verkaart, A. Natsch, R. Landsiedel, 2020, ALTEX.

Robust array-based coregulator binding assay predicting ERα-agonist potency and generating binding profiles reflecting ligand structure.

R. Houtman, I. Rietjens, W. Westerink, 2013, Chemical research in toxicology.