J. Vos

发表

N. Vermeulen, Jolanda van Leeuwen, G. Vredenburg, 2011, Toxicology letters.

Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity.

N. Vermeulen, Shalenie P. den Braver-Sewradj, J. Commandeur, 2017, Toxicology letters.

Human NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated inactivation of reactive quinoneimine metabolites of diclofenac and mefenamic acid.

N. Vermeulen, J. Commandeur, D. Hendriks, 2014, Chemical research in toxicology.

Targeting the ribosome biogenesis key molecule fibrillarin to avoid chemoresistance.

E. Giovannetti, G. Peters, Dzjemma Sarkisjan, 2019, Current medicinal chemistry.

A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants.

Rosa A. Luirink, N. Vermeulen, D. Geerke, 2018, Journal of inorganic biochemistry.

Reconstitution of the interplay between cytochrome P450 and human glutathione S-transferases in clozapine metabolism in yeast.

N. Vermeulen, J. Commandeur, G. Vredenburg, 2013, Toxicology letters.

Inter-individual Variability in Activity of the Major Drug Metabolizing Enzymes in Liver Homogenates of 20 Individuals.

N. Vermeulen, M. van Dijk, Shalenie P. den Braver-Sewradj, 2018, Current drug metabolism.

Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations

N. Vermeulen, Shalenie P. den Braver-Sewradj, J. Commandeur, 2017, Chemical research in toxicology.

Glutathione S-Transferase P1 Protects Against Amodiaquine Quinoneimines-Induced Cytotoxicity but Does Not Prevent Activation of Endoplasmic Reticulum Stress in HepG2 Cells

N. Vermeulen, B. van de Water, Shalenie P. den Braver-Sewradj, 2018, Front. Pharmacol..

Activation of the anticancer drugs cyclophosphamide and ifosfamide by cytochrome P450 BM3 mutants.

N. Vermeulen, Shalenie P. den Braver-Sewradj, B. V. van Vugt-Lussenburg, 2015, Toxicology letters.

Different Reactive Metabolites of Nevirapine Require Distinct Glutathione S-Transferase Isoforms for Bioinactivation.

N. Vermeulen, J. Commandeur, Yongjie Zhang, 2016, Chemical Research in Toxicology.

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

N. Vermeulen, Tibor van Welsem, F. van Leeuwen, 2017, PloS one.

Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion

N. Vermeulen, J. Kooter, J. Vos, 2018, Amino Acids.

Mistaken identity: Paracetamol induces amino acid starvation through mimicry of tyrosine and changes ubiquitin homeostasis

N. Vermeulen, J. Kooter, J. Vos, 2022 .

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

N. Vermeulen, T. Grossmann, W. Bitter, 2018, Applied Microbiology and Biotechnology.

Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

P. Jennings, W. Bitter, J. Commandeur, 2019, Applied Microbiology and Biotechnology.

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer.

N. Vermeulen, Shalenie P. den Braver-Sewradj, J. Commandeur, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

The Role of the Actin Cytoskeleton in Cancer and Its Potential Use as a Therapeutic Target

G. Schevzov, P. Gunning, J. Vos, 2015 .

Drug toxicity profiling of a Saccharomyces cerevisiae deubiquitinase deletion panel shows that acetaminophen mimics tyrosine.

N. Vermeulen, F. van Leeuwen, M. van Dijk, 2018, Toxicology in vitro : an international journal published in association with BIBRA.

Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners

N. Vermeulen, T. Grossmann, W. Bitter, 2018, Applied Microbiology and Biotechnology.

Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.

N. Vermeulen, Jolanda van Leeuwen, J. Vos, 2012, Toxicology in vitro : an international journal published in association with BIBRA.

Practical Guidelines to Redesign Introductory Chemistry Courses Using a Flexible and Adaptive Blended Format

M. Siderius, H. Westbroek, J. Vos, 2021, Journal of Chemical Education.

Function, essentiality, and expression of cytochrome P450 enzymes and their cognate redox partners in Mycobacterium tuberculosis: are they drug targets?

P. Jennings, W. Bitter, J. Commandeur, 2019, Applied Microbiology and Biotechnology.

Subunits Rip1p and Cox9p of the respiratory chain contribute to diclofenac-induced mitochondrial dysfunction.

M. Luttik, N. Vermeulen, G. Smits, 2011, Microbiology.

Selective whole-cell biosynthesis of the designer drug metabolites 15- or 16-betahydroxynorethisterone by engineered Cytochrome P450 BM3 mutants

M. Honing, N. Vermeulen, J. Commandeur, 2015 .

Involvement of the Pleiotropic Drug Resistance Response, Protein Kinase C Signaling, and Altered Zinc Homeostasis in Resistance of Saccharomyces cerevisiae to Diclofenac

Nico P. E. Vermeulen, N. Vermeulen, Jolanda van Leeuwen, 2011, Applied and Environmental Microbiology.