H. Shindoh

发表

Advantages of in vitro cytotoxicity testing by using primary rat hepatocytes in comparison with established cell lines.

Kun Wang, Hidetoshi Shindoh, Ikuo Horii, 2002, Journal of Toxicological Sciences.

Estimating the clinical risk of hypertension from VEGF signal inhibitors by a non-clinical approach using telemetered rats.

H. Shindoh, M. Tabo, R. Komatsu, 2014, The Journal of toxicological sciences.

Comparison of in vitro metabolic conversion of capecitabine to 5-FU in rats, mice, monkeys and humans--toxicological implications.

Takemi Yoshida, H. Shindoh, M. Ishigai, 2011, The Journal of toxicological sciences.

Relationship between AUC of 5'-DFUR and toxicity of capecitabine, fluoropyrimidine carbamate analogs, and 5'-DFUR in monkeys, mice, and rats.

N. Shishido, I. Horii, Kazuko Kobayashi, 2006, The Journal of toxicological sciences.

Effect of dose regimen on the toxicity of 2'-deoxy-2'-methylidenecytidine (DMDC) in monkeys.

N. Shishido, I. Horii, Kazuko Kobayashi, 2007, The Journal of toxicological sciences.

Quantitative evaluation of hepatic and intestinal induction of CYP3A in clinical practice

Motohiro Kato, H. Shindoh, Shino Kuramoto, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Simple Evaluation Method for CYP3A4 Induction from Human Hepatocytes: The Relative Factor Approach with an Induction Detection Limit Concentration Based on the Emax Model

Motohiro Kato, S. Miyauchi, H. Shindoh, 2017, Drug Metabolism and Disposition.

Discovery of [5-Amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone (CH5183284/Debio 1347), An Orally Available and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor.

M. Ohmori, Hiroki Nishii, K. Morikami, 2016, Journal of medicinal chemistry.

Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase.

K. Kawasaki, S. Sogabe, K. Morikami, 2003, Bioorganic & medicinal chemistry.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3.

S. Niizuma, K. Kawasaki, S. Sogabe, 2003, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 3.

S. Niizuma, K. Kawasaki, S. Sogabe, 2003, Bioorganic & medicinal chemistry letters.

Preclinical evaluation of the potential for cytochrome P450 inhibition and induction of the selective ALK inhibitor, alectinib

H. Shindoh, Kenji Takanashi, M. Ishigai, 2017, Xenobiotica; the fate of foreign compounds in biological systems.

The Fibroblast Growth Factor Receptor Genetic Status as a Potential Predictor of the Sensitivity to CH5183284/Debio 1347, a Novel Selective FGFR Inhibitor

K. Morikami, H. Shindoh, N. Ishii, 2014, Molecular Cancer Therapeutics.

Small Molecule Therapeutics The Fibroblast Growth Factor Receptor Genetic Status as a Potential Predictor of the Sensitivity to CH 5183284 / Debio 1347 , a Novel Selective FGFR Inhibitor

K. Morikami, H. Shindoh, N. Ishii, 2014 .

Enantioselective synthesis of derivatives and structure-activity relationship study in the development of NA255 as a novel host-targeting anti-HCV agent.

M. Aoki, H. Sakamoto, K. Kawasaki, 2013, Bioorganic & medicinal chemistry letters.

Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 2.

K. Kawasaki, S. Sogabe, K. Morikami, 2002, Bioorganic & medicinal chemistry letters.

Cassette Dosing Approach and Quantitative Structure-Pharmacokinetic Relationship Study of Antifungal N-Myristoyltransferase Inhibitors

Kiyoshi Hasegawa, Yuko Aoki, Nobuo Shimma, 2002, J. Chem. Inf. Comput. Sci..