H. Iwabuchi

发表

Formation of a novel quinone epoxide metabolite of troglitazone with cytotoxicity to HepG2 cells.

H. Yamazaki, Yui Yamamoto, M. Nakajima, 2002, Drug metabolism and disposition: the biological fate of chemicals.

CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528

H. Saji, M. Kotsuma, H. Iwabuchi, 2008, Drug Metabolism and Disposition.

Glutathione S-transferase pi trapping method for generation and characterization of drug-protein adducts in human liver microsomes using liquid chromatography-tandem mass spectrometry.

Hideo Yukinaga, T. Izumi, H. Iwabuchi, 2012, Journal of pharmaceutical and biomedical analysis.

In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes

M. Uchiyama, T. Izumi, H. Iwabuchi, 2011, Drug Metabolism and Disposition.

Microsoft Word-87912151-file00

M. Uchiyama, H. Iwabuchi, O. Okazaki, 2011 .

Inhibition of In Vitro Metabolism of Simvastatin by Itraconazole in Humans and Prediction of In Vivo Drug-Drug Interactions

Y. Sugiyama, Kiyomi Ito, T. Kondo, 2001, Pharmaceutical Research.

Disposition and metabolism of the new oral antidiabetic drug troglitazone in rats, mice and dogs.

T. Kinoshita, H. Iwabuchi, K. Nakamura, 1997, Arzneimittel-Forschung.

Repeated glucuronidation at one hydroxyl group leads to structurally novel diglucuronides of steroid sex hormones.

H. Iwabuchi, T. Ikeda, T. Murai, 2005, Drug metabolism and pharmacokinetics.

Structure Elucidation of Novel Metabolites of Gemfibrozil in Dog : Conjugation Reaction of Conjugated Metabolites

H. Yoshii, M. Ishikawa, H. Iwabuchi, 2004 .

Pharmacokinetics, Metabolism, and Disposition of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rats and Monkeys

M. Uchiyama, T. Izumi, K. Abe, 2011, Drug Metabolism and Disposition.

Induction of peroxisome proliferation in rat liver by dietary treatment with 2,2,4,4,6,8,8-heptamethylnonane.

T. Suga, H. Iwabuchi, K. Fukuda, 1988, Xenobiotica; the fate of foreign compounds in biological systems.

HUMAN UDP-GLUCURONOSYLTRANSFERASE, UGT1A8, GLUCURONIDATES DIHYDROTESTOSTERONE TO A MONOGLUCURONIDE AND FURTHER TO A STRUCTURALLY NOVEL DIGLUCURONIDE

H. Iwabuchi, T. Ikeda, T. Murai, 2006, Drug Metabolism and Disposition.

Formation of a structurally novel, serial diglucuronide of 4-hydroxybiphenyl by further glucuronidation of a monoglucuronide in dog liver microsomes.

H. Iwabuchi, F. Tsuruta, T. Ikeda, 2002, Drug metabolism and pharmacokinetics.

Characterization of Phenotypes in Gstm1-null Mice by Cytosolic and in Vivo Metabolic Studies Using 1,2-Dichloro-4-Nitrobenzene

S. Manabe, T. Yamoto, M. Uchiyama, 2006, Drug Metabolism and Disposition.

Characterization of phenotypes in Gstm1 -null mice by cytosolic and in vivo metabolic studies using DCNB

S. Manabe, M. Uchiyama, Yosuke Ando, 2006 .

metabolic studies using DCNB

S. Manabe, M. Uchiyama, Yosuke Ando, 2006 .

Metabolism of pravastatin sodium in isolated rat hepatocytes. I. Glutathione conjugate formation reaction.

T. Kinoshita, H. Iwabuchi, S. Muramatsu, 1992, Xenobiotica; the fate of foreign compounds in biological systems.

Biotransformation of pravastatin sodium (I). Mechanisms of enzymic transformation and epimerization of an allylic hydroxy group of pravastatin sodium.

H. Iwabuchi, S. Muramatsu, M. Tanaka, 1993, Biochemical and biophysical research communications.

Biotransformation of Prasugrel, a Novel Thienopyridine Antiplatelet Agent, to the Pharmacologically Active Metabolite

Hiroyuki Kobayashi, N. Farid, A. Kurihara, 2010, Drug Metabolism and Disposition.

Pharmacokinetics and disposition of CS-0777, a sphingosine 1-phosphate receptor modulator, in rats and monkeys

T. Izumi, T. Ikeda, H. Iwabuchi, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Hexavalent glycoclusters having tris-bipyridine ferrous complex cores as minimum combinatorial libraries for probing carbohydrate–carbohydrate interactions

Teruaki Hasegawa, H. Iwabuchi, Y. Nonaka, 2016 .

High-Throughput Evaluation System based on Fluorescence Intensity Distribution Analysis-Polarization to Investigate Carbohydrate–Carbohydrate Interactions

Teruaki Hasegawa, H. Iwabuchi, Y. Nonaka, 2016 .

Disposition and Metabolism of the Oral Antidiabetic Drug Troglitazone in Monkeys

H. Haruyama, H. Ikenaga, M. Ishikawa, 2000 .

Studies on drug metabolism using liquid chromatography/mass spectrometry: Comparison of three liquid chromatographic/mass spectrometric interfaces

Hidetoshi Watanabe, N. Kobayashi, H. Iwabuchi, 1994 .

Analysis of non-volatile compounds by off-line LC/MS.

H. Iwabuchi, H. Nagashima, Kan Nakamura, 1988 .

Simultaneous determination of gemfibrozil and its metabolites in plasma and urine by a fully automated high performance liquid chromatographic system.

K. Nakamura, H. Iwabuchi, A. Nakagawa, 1991, Biomedical chromatography : BMC.

Ethylene Glycol Monomethyl Ether–Induced Toxicity Is Mediated through the Inhibition of Flavoprotein Dehydrogenase Enzyme Family

Osamu Okazaki, Lining Guo, Naoki Kiyosawa, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Antitumor activity and novel DNA‐self‐strand‐breaking mechanism of CNDAC (1‐(2‐C‐cyano‐2‐deoxy‐β‐d‐ARABINO‐Pentofuranosyl) cytosine) and its N4‐palmitoyl derivative (CS‐682)

A. Tomida, T. Tsuruo, Y. Wataya, 1999, International journal of cancer.

Identification of Novel Metabolic Pathways of Pioglitazone in Hepatocytes: N-Glucuronidation of Thiazolidinedione Ring and Sequential Ring-Opening Pathway

M. Uchiyama, T. Izumi, H. Iwabuchi, 2010, Drug Metabolism and Disposition.

Stereospecific taurine conjugation of the trans-OH metabolite (active metabolite) of CS-670, a new 2-arylpropionic acid nonsteroidal anti-inflammatory drug, in dogs.

H. Haruyama, W. Takasaki, H. Iwabuchi, 1995, Biological & pharmaceutical bulletin.

Isolation and Identification of Diglucuronides of Some Endogenous Steroids in Dogs

M. Takei, H. Iwabuchi, Kohji Tanaka, 2008, Drug Metabolism and Disposition.

In Vitro Metabolism of Rivoglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, in Rat, Monkey, and Human Liver Microsomes and Freshly Isolated Hepatocytes

M. Uchiyama, T. Izumi, H. Iwabuchi, 2011, Drug Metabolism and Disposition.

Identification of Gemfibrozil Metabolites, Produced as Positional Isomers in Human Liver Microsomes, by On-line Analyses Using Liquid Chromatography/Mass Spectrometry and Liquid Chromatography/Nuclear Magnetic Resonance Spectroscopy

H. Iwabuchi, T. Ikeda, T. Murai, 2004 .

Biotransformation of Prasugrel, a Novel Thienopyridine Antiplatelet Agent, to the Pharmacologically Active Metabolite

Hiroyuki Kobayashi, N. Farid, A. Kurihara, 2010, Drug Metabolism and Disposition.