T. Baba

发表

Enzymic reduction of N-hydroxyamphetamine: the role of electron transfer system containing cytochrome b5.

H. Yamada, T. Baba, K. Oguri, 1988, Biochemical pharmacology.

Different contribution of CYP2C19 in the in vitro metabolism of three proton pump inhibitors.

M. Kasuga, N. Aoyama, T. Sakaeda, 2003, Biological & pharmaceutical bulletin.

Model for the drug–drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans

T. Kanazu, N. Okamura, T. Baba, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Quantitation of cytochrome P450 enzymes (CYP1A1/2, 2B11, 2C21 and 3A12) in dog liver microsomes by enzyme-linked immunosorbent assay.

K. Eguchi, T. Baba, Y. Nishibe, 1996, Xenobiotica; the fate of foreign compounds in biological systems.

The Importance of Cytochrome P450 3A Enzymes in Drug Metabolism

T. Shimada, F. Guengerich, K. Raney, 1994 .

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

F. Guengerich, E. Gillam, S. Ohmori, 1993, Archives of biochemistry and biophysics.

Expression of modified cytochrome P450 2C10 (2C9) in Escherichia coli, purification, and reconstitution of catalytic activity.

F. Guengerich, T. Baba, P. Sandhu, 1993, Archives of biochemistry and biophysics.

Identification of the transporters involved in the hepatobiliary transport and intestinal efflux of S-8921 glucuronide , a pharmacologically active metabolite of S-8921

H. Kusuhara, Y. Sugiyama, T. Baba, 2008 .

Identification of the Transporters Involved in the Hepatobiliary Transport and Intestinal Efflux of Methyl 1-(3,4-Dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) Glucuronide, a Pharmacologically Active Metabolite of S-8921

H. Kusuhara, Y. Sugiyama, T. Baba, 2008, Drug Metabolism and Disposition.

Cloning of a cDNA encoding a novel marmoset CYP2C enzyme, expression in yeast cells and characterization of its enzymatic functions.

Keita Saito, S. Narimatsu, T. Katsu, 2006, Biochemical pharmacology.

A new cytochrome P450 form belonging to the CYP2D in dog liver microsomes: purification, cDNA cloning, and enzyme characterization.

R. Kato, T. Matsubara, T. Baba, 1995, Archives of biochemistry and biophysics.

Induction of intestinal cytochrome P450 (CYP3A) by rifampicin in beagle dogs.

T. Baba, T. Maruyama, T. Harauchi, 2001, Chemico-biological interactions.

Contribution of CYP4A8 to the formation of 20-hydroxyeicosatetraenoic acid from arachidonic acid in rat kidney.

S. Imaoka, Y. Funae, H. Hasegawa, 2002, Drug metabolism and pharmacokinetics.

Studies on N-demethylation of methamphetamine by liver microsomes of guinea-pigs and rats: the role of flavin-containing mono-oxygenase and cytochrome P-450 systems.

H. Yamada, T. Baba, K. Oguri, 1984, Xenobiotica; the fate of foreign compounds in biological systems.

Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment.

H. Hasegawa, N. Okamura, E. Kanaoka, 2008, Drug metabolism and pharmacokinetics.

Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug–drug interaction model rats

T. Kanazu, N. Okamura, T. Baba, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

Model for the drug–drug interaction responsible for CYP3A enzyme inhibition. II: establishment and evaluation of dexamethasone-pretreated female rats

T. Kanazu, N. Okamura, T. Baba, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: discovery of CB2 receptor selective compounds.

K. Kawamoto, H. Nakazato, H. Kai, 2007, Bioorganic & medicinal chemistry letters.

A new metabolite of methamphetamine; evidence for formation of N-[(1-methyl-2-phenyl)ethyl]ethanimine N-oxide.

H. Yamada, T. Baba, K. Oguri, 1987, Xenobiotica; the fate of foreign compounds in biological systems.

Synthesis and activities of oxidative metabolites of the anti-arthritic drug candidate S-2474.

Katsutoshi Yamada, T. Baba, S. Matsumoto, 2003, Bioorganic & medicinal chemistry.

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: orally bioavailable compounds.

H. Kai, T. Yoshikawa, T. Baba, 2007, Bioorganic & medicinal chemistry letters.

Species differences in β-oxidative metabolism of a thromboxane A2-receptor antagonist [(+)-S-145] in rat, dog and monkey

T. Baba, Y. Yamaguchi, T. Matsubara, 2001, Xenobiotica; the fate of foreign compounds in biological systems.

Investigation of drug–drug interaction via mechanism‐based inhibition of cytochrome P450 3A by macrolides in dexamethasone‐treated female rats

T. Kanazu, T. Baba, Y. Yamaguchi, 2012, Biopharmaceutics & drug disposition.

Participation of cytochrome P-450 isozymes in N-demethylation, N-hydroxylation and aromatic hydroxylation of methamphetamine.

H. Yamada, T. Baba, K. Oguri, 1988, Xenobiotica; the fate of foreign compounds in biological systems.

Metabolism of sertindole: identification of the metabolites in the rat and dog, and species comparison of liver microsomal metabolism.

H. Pedersen, T. Baba, J. Perregaard, 1995, Xenobiotica; the fate of foreign compounds in biological systems.

Expression of modified human cytochrome P450 1A2 in Escherichia coli: stabilization, purification, spectral characterization, and catalytic activities of the enzyme.

R. Tukey, F. Guengerich, M. Martín, 1994, Archives of biochemistry and biophysics.

Sex differences in the metabolism of (+)-S-145, a novel thromboxane A2 receptor antagonist in rat.

K. Mizojiri, T. Baba, Y. Yamaguchi, 1996, Xenobiotica; the fate of foreign compounds in biological systems.

Characterization of cytochrome P-450 2B6 in human liver microsomes.

H. Yamazaki, T. Shimada, F. Guengerich, 1993, Drug metabolism and disposition: the biological fate of chemicals.

IDENTIFICATION OF RAT AND HUMAN CYTOCHROME P 450 FORMS INVOLVED IN THE METABOLISM OF THE THROMBOXANE A 2 RECEPTOR ANTAGONIST

R. Tukey, F. Guengerich, T. Baba, 1997 .

Identification of rat and human cytochrome P450 forms involved in the metabolism of the thromboxane A2 receptor antagonist (+)-S-145.

R. Tukey, F. Guengerich, T. Baba, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Effects of serum albumin and liver cytosol on CYP2C9- and CYP3A4-mediated drug metabolism.

Y. Sugiyama, Kiyomi Ito, Y. Ohno, 2002, Drug metabolism and pharmacokinetics.

Glucuronidation Converting Methyl 1-(3,4-Dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) to a Potent Apical Sodium-Dependent Bile Acid Transporter Inhibitor, Resulting in a Hypocholesterolemic Action

H. Kusuhara, Y. Sugiyama, T. Kanazu, 2007, Journal of Pharmacology and Experimental Therapeutics.

H. Kusuhara, Y. Sugiyama, T. Baba, 2008, Drug Metabolism and Disposition.