V. Gire

发表

Reciprocal regulation of p21 and Chk1 controls the Cyclin D1-RB pathway to mediate senescence onset after DNA damage-induced G2 arrest

V. Dulic, Anđela Horvat, V. Georget, 2021, bioRxiv.

Control of Replicative Life Span in Human Cells: Barriers to Clonal Expansion Intermediate Between M1 Senescence and M2 Crisis

P. Smith, J. Bond, F. Wyllie, 1999, Molecular and Cellular Biology.

DNA damage checkpoint kinase Chk2 triggers replicative senescence

V. Dulic, D. Wynford‐Thomas, P. Roux, 2004, The EMBO journal.

An amphotropic retroviral vector expressing a mutant gsp oncogene: effects on human thyroid cells in vitro.

M. Ivan, J. Bond, D. Wynford‐Thomas, 1997 .

The p53 Isoform Δ133p53β Promotes Cancer Stem Cell Potential

P. Roux, F. Hollande, M. Busson, 2015, Stem cell reports.

Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.

J. Blaydes, J. Bond, F. Wyllie, 1996, Oncogene.

Contrasting effects of activating mutations of GαS and the thyrotropin receptor on proliferation and differentiation of thyroid follicular cells

M. Ivan, D. Wynford‐Thomas, R. Ajjan, 1999, Oncogene.

Dynamic analysis of drug action on in vitro reconstituted thyroid follicle by microinjection of tracer molecules and videomicroscopy

P. Fonlupt, B. Rousset, V. Gire, 1992, Cell Biology and Toxicology.

Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts

J. Piette, V. Dulic, D. Fisher, 2003, The EMBO journal.

[Senescence: a telomeric limit to immortality or a cellular response to physiologic stresses?].

V. Gire, 2005, Medecine sciences : M/S.

Dysfunctional Telomeres at Senescence Signal Cell Cycle Arrest via Chk2

V. Gire, 2004, Cell cycle.

Reinitiation of DNA Synthesis and Cell Division in Senescent Human Fibroblasts by Microinjection of Anti-p53 Antibodies

D. Wynford‐Thomas, V. Gire, 1998, Molecular and Cellular Biology.

Reinitiation of DNA Synthesis and Cell Division in Senescent Human Fibroblasts by Microinjection of Anti-p53 Antibodies

D. Wynford‐Thomas, V. Gire, 1998, Molecular and Cellular Biology.

Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2

J. Blaydes, D. Wynford‐Thomas, V. Gire, 1997, Oncogene.

Multinucleated cells can continuously generate mononucleated cells in the absence of mitosis: a study of cells of the avian osteoclast lineage.

E. Lazarides, C. Woods, B. Rousset, 1995, Journal of cell science.

Senescence from G2 arrest, revisited

V. Gire, V. Dulić, 2015, Cell cycle.

Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras

C. Marshall, D. Wynford‐Thomas, V. Gire, 1999, Oncogene.

GWL overexpression promotes transformation of immortalised mammary gland cells and primary human fibroblast

A. Castro, S. Vigneron, T. Lorca, 2016 .

Greatwall promotes cell transformation by hyperactivating AKT in human malignancies

A. Castro, S. Vigneron, T. Lorca, 2015, eLife.

An amphotropic retroviral vector expressing a mutant gsp oncogene: effects on human thyroid cells in vitro.

M Ivan, M Ludgate, V Gire, 1997, The Journal of clinical endocrinology and metabolism.

Mechanisms and Regulation of Cellular Senescence

L. Roger, V. Gire, Fanny Tomas, 2021, International journal of molecular sciences.

PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS

C. Marshall, D. Wynford‐Thomas, V. Gire, 2000, Oncogene.

Gain of oncogenic function of p53 mutants regulates E-cadherin expression uncoupled from cell invasion in colon cancer cells

P. Roux, L. Roger, V. Gire, 2010, Journal of Cell Science.

Calcium is transported into the lumen of pig thyroid follicles by fluid phase basolateral to apical transcytosis

P. Fonlupt, B. Rousset, V. Gire, 1997, Journal of cellular physiology.

Endocytosis of albumin and thyroglobulin at the basolateral membrane of thyrocytes organized in follicles.

B. Rousset, V. Gire, Z. Kostrouch, 1996, Endocrinology.

Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response

Pierre Roux, P. Roux, V. Gire, 2012, Nucleic acids research.

p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress.

J. Piette, J. Sedivy, V. Gire, 2004, Molecular biology of the cell.

TNFα induces sequential activation of Cdc42- and p38/p53-dependent pathways that antagonistically regulate filopodia formation

Pierre Roux, P. Roux, Gilles Gadea, 2004, Journal of Cell Science.

Protein endocytosis by a kidney tubule suspension: metabolic requirements.

G. Baverel, H. Simonnet, V. Gire, 1994, Biochimica et biophysica acta.

RAS oncogene activation induces proliferation in normal human thyroid epithelial cells without loss of differentiation

D. Wynford‐Thomas, V. Gire, 2000, Oncogene.

Reciprocal regulation of p21 and Chk1 controls the Cyclin D1-RB pathway to mediate senescence onset after G2 arrest.

Anđela Horvat, V. Georget, D. Fisher, 2022, Journal of cell science.