Nozomi Tomimatsu

发表

Modulation of the DNA-damage response to HZE particles by shielding.

Jack Miller, S. Burma, B. Mukherjee, 2008, DNA repair.

Ku70/80 Modulates ATM and ATR Signaling Pathways in Response to DNA Double Strand Breaks*

David J. Chen, M. Oshimura, S. Burma, 2007, Journal of Biological Chemistry.

Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing

E. Greene, S. Burma, Youngho Kwon, 2022, Nature Communications.

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions.

K. Khanna, S. Burma, A. Kurimasa, 2012, DNA repair.

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

T. Pandita, K. Khanna, S. Burma, 2009, Nucleic acids research.

Phosphorylation of Exo 1 modulates homologous recombination repair of DNA double-strand breaks

T. Pandita, K. Khanna, S. Burma, 2010 .

Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells.

R. Nishigaki, M. Oshimura, K. Kaibuchi, 2006, Biochemical and biophysical research communications.

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

K. Khanna, B. Llorente, J. Harris, 2014, Nature Communications.

DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair

K. Khanna, J. Harris, S. Burma, 2017, The Journal of Biological Chemistry.

Distinct roles of ATR and DNA‐PKcs in triggering DNA damage responses in ATM‐deficient cells

S. Burma, B. Mukherjee, Nozomi Tomimatsu, 2009, EMBO reports.

Abstract 523: Activating mutations in EGFR abrogate hypoxia-associated radiation resistance in non-small cell lung cancer

M. Story, L. Ding, S. Burma, 2016 .

INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells.

S. Burma, Nozomi Tomimatsu, P. Jalinot, 2016, Cancer research.

Immunofluorescence-based methods to monitor DNA end resection.

S. Burma, B. Mukherjee, Nozomi Tomimatsu, 2015, Methods in molecular biology.

DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification

M. Story, S. Burma, R. Bachoo, 2014, Oncogene.

PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

S. Burma, R. Bachoo, B. Mukherjee, 2010, Cancer research.

The Dual PI 3 K / mTOR Inhibitor NVP-BEZ 235 Is a Potent Inhibitor of ATM-and DNA-PKCs-Mediated DNA Damage Responses 1 , 2

S. Burma, N. Pichamoorthy, B. Mukherjee, 2014 .

Inhibition of DNA Double-Strand Break Repair by the Dual PI3K/mTOR Inhibitor NVP-BEZ235 as a Strategy for Radiosensitization of Glioblastoma

Xian-Jin Xie, S. Burma, R. Bachoo, 2013, Clinical Cancer Research.

The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses.

S. Burma, N. Pichamoorthy, B. Mukherjee, 2012, Neoplasia.

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions

E. Williamson, S. Burma, B. Mukherjee, 2020, Nature Communications.

Construction of a novel expression system on a human artificial chromosome.

David J. Chen, M. Oshimura, A. Kurimasa, 2005, Biochemical and Biophysical Research Communications - BBRC.

The yeast Fun30 and human SMARCAD1 chromatin remodelers promote DNA end resection

Agnès Thierry, A. Thierry, B. Llorente, 2012, Nature.

Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence

R. Kittler, P. Sung, Eliot Fletcher-Sananikone, 2021, Cancer Research.

EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.

Bruce Mickey, Kimmo J Hatanpaa, W. Cavenee, 2009, Cancer research.

Molecular and Cellular Pathobiology INT 6 / EIF 3 E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells

K. Khanna, S. Burma, D. Richard, 2012 .

Molecular and Cellular Pathobiology INT 6 / EIF 3 E Interacts with ATM and Is Required for Proper Execution of the DNA Damage Response in Human Cells

K. Khanna, S. Burma, D. Richard, 2012 .

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions

P. Sung, R. Hromas, E. Williamson, 2020, Nature Communications.

EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork–Associated DNA Damage Repair

M. Story, L. Ding, S. Burma, 2017, Molecular Cancer Research.

AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells.

R. Bristow, S. Burma, D. Saha, 2012, International journal of radiation oncology, biology, physics.