A. Tanaka

发表

Intranasal rifampicin for Alzheimer's disease prevention

A. Yamamoto, T. Tomiyama, T. Umeda, 2018, Alzheimer's & dementia.

Roles of enterobacteria, nitric oxide and neutrophil in pathogenesis of indomethacin-induced small intestinal lesions in rats.

K. Takeuchi, A. Konaka, T. Kunikata, 1999, Pharmacological research.

Role of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.

K. Takeuchi, A. Tanaka, R. Ohno, 2003, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Rofecoxib Produces Intestinal but Not Gastric Damage in the Presence of a Low Dose of Indomethacin in Rats

K. Takeuchi, A. Tanaka, A. Yokota, 2005, Journal of Pharmacology and Experimental Therapeutics.

Development of a Phosphoric Acid-Mediated Hyaluronic Acid Gel Sheet for Efficient Transdermal Delivery of Alendronate for Anti-Osteoporotic Therapy

H. Katsumi, Masaki Morishita, A. Yamamoto, 2019, Pharmaceutics.

Nasal Drug Absorption from Powder Formulations: Effect of Fluid Volume Changes on the Mucosal Surface.

H. Katsumi, A. Yamamoto, A. Tanaka, 2017, Biological & pharmaceutical bulletin.

Pathogenic Importance of Intestinal Hypermotility in NSAID-Induced Small Intestinal Damage in Rats

K. Takeuchi, T. Kunikata, A. Tanaka, 2002, Digestion.

Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage.

K. Takeuchi, A. Tanaka, T. Miyazawa, 2002, The Journal of pharmacology and experimental therapeutics.

16,16-Dimethyl Prostaglandin E2 Inhibits Indomethacin-Induced Small Intestinal Lesions Through EP3 and EP4 Receptors

K. Takeuchi, T. Kunikata, A. Tanaka, 2002, Digestive Diseases and Sciences.

Functional mechanism underlying cyclooxygenase‐2 expression in rat small intestine following administration of indomethacin: Relation to intestinal hypermotility

K. Takeuchi, Y. Hayashi, A. Tanaka, 2005, Journal of gastroenterology and hepatology.

Modulation of Intestinal Transport and Absorption of Topotecan, a BCRP Substrate, by Various Pharmaceutical Excipients and Their Inhibitory Mechanisms of BCRP Transporter.

H. Katsumi, Masaki Morishita, A. Yamamoto, 2019, Journal of pharmaceutical sciences.

The roles of nitric oxide and prostaglandins in alterations of ulcerogenic and healing responses in adjuvant‐induced arthritic rat stomachs

K. Takeuchi, T. Kunikata, A. Tanaka, 2000, Alimentary pharmacology & therapeutics.

Changes in gastric mucosal ulcerogenic responses in rats with adjuvant arthritis: role of nitric oxide

K. Takeuchi, T. Kunikata, A. Tanaka, 1999, Alimentary pharmacology & therapeutics.

Direct Delivery of ANA-TA9, a Peptide Capable of Aβ Hydrolysis, to the Brain by Intranasal Administration

A. Tanaka, T. Sakane, T. Furubayashi, 2021, Pharmaceutics.

Effect of YM435, a novel dopamine DA1 receptor agonist, in a canine model of acute congestive heart failure.

Y. Arai, K. Sudoh, T. Takenaka, 1998, General pharmacology.

Morphology of aging lung in F344/N rat: alveolar size, connective tissue, and smooth muscle cell markers.

Y. Atoji, Yoshio Yamamoto, Yoshitaka Suzuki, 2003, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

Healing of Duodenal Ulcers Is Not Impaired by Indomethacin or Rofecoxib, the Selective COX-2 Inhibitor, in Rats

K. Takeuchi, A. Tanaka, M. Matsumoto, 2002, Digestion.

Roles of Endogenous Prostaglandins and Cyclooxygenase Isozymes in Healing of Indomethacin-Induced Small Intestinal Lesions in Rats

K. Takeuchi, A. Tanaka, R. Ohno, 2006, Journal of Pharmacology and Experimental Therapeutics.

Dual action of nitric oxide in pathogenesis of indomethacin-induced small intestinal ulceration in rats.

K. Takeuchi, T. Kunikata, A. Tanaka, 1999, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[Gastrointestinal sparing anti-inflammatory drugs--COX-2 selective inhibitors and NO-releasing NSAIDs].

K. Takeuchi, A. Tanaka, 2001, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Role of endogenous nitric oxide (NO) and NO synthases in healing of indomethacin-induced intestinal ulcers in rats.

K. Takeuchi, A. Tanaka, R. Ohno, 2007, Life sciences.

Dexamethasone Damages the Rat Stomach but Not Small Intestine During Inhibition of COX-1

K. Takeuchi, A. Tanaka, A. Yokota, 2007, Digestive Diseases and Sciences.

Protection by constitutively formed nitric oxide of intestinal damage induced by indomethacin in rats

K. Takeuchi, H. Mizoguchi, T. Kunikata, 2001, Journal of Physiology-Paris.

Inducible types of cyclooxygenase and nitric oxide synthase in adaptive cytoprotection in rat stomachs

K. Takeuchi, T. Kunikata, A. Tanaka, 1998, Journal of Physiology-Paris.

Gastroprotective action of glucocorticoid hormones during NSAID treatment

K. Takeuchi, A. Tanaka, L. Filaretova, 2006, InflammoPharmacology.

Mechanisms by which endogenous glucocorticoid protects against indomethacin-induced gastric injury in rats.

K. Takeuchi, A. Tanaka, S. Kato, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Selective cyclooxygenase-2 inhibitor induces gastric mucosal damage in adrenalectomized rats

K. Takeuchi, A. Tanaka, L. Filaretova, 2002, InflammoPharmacology.

Hemodynamic characterization of YM435, a novel dopamine DA1 receptor agonist, in anesthetized dogs.

T. Takenaka, A. Tanaka, K. Honda, 1997, Journal of cardiovascular pharmacology.

Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons

A. Tanaka, K. Nagasawa, K. Nagai, 2007, Glia.

Preconditioning Stress Prevents Cold Restraint Stress-Induced Gastric Lesions in Rats: Roles of COX-1, COX-2, and PLA2

K. Takeuchi, A. Tanaka, L. Filaretova, 2007, Digestive Diseases and Sciences.

Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.

K. Takeuchi, H. Satoh, A. Tanaka, 2010, Clinica chimica acta; international journal of clinical chemistry.

S1625 Effect of Cj-42794, a Selective Antagonist of Prostaglandin E Receptor Subtype 4, On Ulcerogenic and Healing Responses in Rat Gastrointestinal Mucosa

K. Takeuchi, A. Tanaka, S. Kato, 2008 .

Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors.

K. Takeuchi, A. Tanaka, S. Kato, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Factors Involved in Upregulation of Inducible Nitric Oxide Synthase in Rat Small Intestine Following Administration of Nonsteroidal Anti-inflammatory Drugs

K. Takeuchi, A. Tanaka, A. Yokota, 2006, Digestive Diseases and Sciences.

Development of intestinal, but not gastric damage caused by a low dose of indomethacin in the presence of rofecoxib

K. Takeuchi, A. Tanaka, A. Yokota, 2006, InflammoPharmacology.

Induction of Small Intestinal Damage in Rats Following Combined Treatment with Cyclooxygenase-2 and Nitric-Oxide Synthase Inhibitors

K. Takeuchi, A. Tanaka, R. Ohno, 2004, Journal of Pharmacology and Experimental Therapeutics.

Functional Mechanism Underlying COX-2 Expression Following Administration of Indomethacin in Rat Stomachs: Importance of Gastric Hypermotility

K. Takeuchi, Y. Hayashi, A. Tanaka, 2004, Digestive Diseases and Sciences.

Induction of intestinal damage by rofecoxib, the selective COX-2 inhibitor, under inhibition of nitric oxide production in rats

K. Takeuchi, Y. Hayashi, A. Tanaka, 2002, InflammoPharmacology.

NSAID-induced small intestinal damage: role of COX inhibition

K. Takeuchi, A. Tanaka, S. Kato, 2002, InflammoPharmacology.

Role of Cyclooxygenase (COX)-1 and COX-2 Inhibition in Nonsteroidal Anti-Inflammatory Drug-Induced Intestinal Damage in Rats: Relation to Various Pathogenic Events

K. Takeuchi, A. Tanaka, R. Ohno, 2002, Journal of Pharmacology and Experimental Therapeutics.

Up‐regulation of COX‐2 by inhibition of COX‐1 in the rat: a key to NSAID‐induced gastric injury

K. Takeuchi, A. Tanaka, S. Hase, 2002, Alimentary pharmacology & therapeutics.

Inhibition of both COX-1 and COX-2 is required for development of gastric damage in response to nonsteroidal antiinflammatory drugs

K. Takeuchi, A. Tanaka, S. Hase, 2001, Journal of Physiology-Paris.

Oral but Not Parenteral Aspirin Upregulates COX-2 Expression in Rat Stomachs

K. Takeuchi, A. Tanaka, A. Yokota, 2006, Digestion.

Prostaglandin E2 stimulates VEGF expression in primary rat gastric fibroblasts through EP4 receptors

K. Takeuchi, A. Tanaka, K. Kamei, 2007, Inflammopharmacology.

Research Article Prostaglandin E 2 stimulates VEGF expression in primary rat gastric fi broblasts through EP4 receptors

K. Takeuchi, A. Tanaka, K. Kamei, 2007 .

Effect of YM435, a dopamine DA1 receptor agonist, in a canine model of ischemic acute renal failure.

Y. Arai, T. Takenaka, A. Tanaka, 1998, General pharmacology.

Quantitative estimation of drug permeation through nasal mucosa using in vitro membrane permeability across Calu-3 cell layers for predicting in vivo bioavailability after intranasal administration to rats.

K. Sugano, A. Tanaka, T. Sakane, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Nasal drug absorption from powder formulations: The effect of three types of hydroxypropyl cellulose (HPC)

H. Katsumi, A. Yamamoto, A. Tanaka, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Enhancement of Nasal Drug Absorption From Powder Formulations by the Addition of Sodium Carboxymethyl Cellulose

H. Katsumi, A. Yamamoto, A. Tanaka, 2016, IEEE Transactions on NanoBioscience.

Inhibition of small‐conductance Cl− channels by the interleukin‐1β‐stimulated production of superoxide in rabbit gastric parietal cells

A. Ikari, Tomoyuki Suzuki, A. Tanaka, 2003, The Journal of physiology.

Dopamine DA1 receptor agonist activity of YM435 in the canine renal vasculature.

T. Takenaka, A. Tanaka, W. Uchida, 1997, General pharmacology.

Application of a Microreactor to Pharmaceutical Manufacturing: Preparation of Amorphous Curcumin Nanoparticles and Controlling the Crystallinity of Curcumin Nanoparticles by Ultrasonic Treatment

A. Tanaka, T. Sakane, T. Furubayashi, 2019, AAPS PharmSciTech.

Hypothalamic-pituitary-adrenocortical axis: the hidden gold in gastric mucosal homeostasis

K. Takeuchi, A. Tanaka, L. Filaretova, 2006, InflammoPharmacology.

Lack of small intestinal ulcerogenecity of nitric oxide‐releasing indomethacin, NCX‐530, in rats

K. Takeuchi, A. Tanaka, S. Hase, 2001, Alimentary pharmacology & therapeutics.

Effects of TAK-480, a novel tachykinin NK(2)-receptor antagonist, on visceral hypersensitivity in rabbits and ricinoleic acid-induced defecation in guinea pigs.

Takahiro Tanaka, A. Tanaka, M. Toyoda, 2012, Journal of pharmacological sciences.

Topical Xerostomia Treatment with Hyaluronate Sheets Containing Pilocarpine.

T. Ueno, A. Tanaka, T. Sakane, 2022, Biological & pharmaceutical bulletin.

Evaluation of the Pharmacokinetics of Intranasal Drug Delivery for Targeting Cervical Lymph Nodes in Rats

A. Tanaka, T. Sakane, T. Furubayashi, 2021, Pharmaceutics.

Protective effect of rebamipide on indomethacin‐induced intestinal damage in rats

K. Takeuchi, H. Mizoguchi, A. Tanaka, 2001, Journal of gastroenterology and hepatology.

Intestinal protection by lafutidine, a histamine H(2)-receptor antagonist, against indomethacin-induced damage in rats--role of endogenous nitric oxide.

K. Takeuchi, A. Tanaka, T. Miyazawa, 2001, Medical science monitor : international medical journal of experimental and clinical research.

Protective Effect of Lafutidine against Indomethacin-Induced Intestinal Ulceration in Rats: Relation to Capsaicin-Sensitive Sensory Neurons

K. Takeuchi, T. Kunikata, A. Tanaka, 2000, Digestion.

Delayed Healing of Gastric Ulcers in Adjuvant Arthritis Rats: Role of Acid Secretion and Basic Fibroblast Growth Factor

K. Takeuchi, T. Kunikata, A. Tanaka, 2001, Digestion.

Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats.

K. Takeuchi, A. Konaka, T. Kunikata, 1999, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

Effect of (S)-4-(1-(5-Chloro-2-(4-fluorophenyoxy)benzamido)ethyl) Benzoic Acid (CJ-42794), a Selective Antagonist of Prostaglandin E Receptor Subtype 4, on Ulcerogenic and Healing Responses in Rat Gastrointestinal Mucosa

K. Takeuchi, A. Tanaka, S. Kato, 2007, Journal of Pharmacology and Experimental Therapeutics.

Brain and Nasal Cavity Anatomy of the Cynomolgus Monkey: Species Differences from the Viewpoint of Direct Delivery from the Nose to the Brain

A. Tanaka, T. Sakane, T. Furubayashi, 2020, Pharmaceutics.

Effect of polaprezinc on impaired healing of chronic gastric ulcers in adjuvant-induced arthritic rats--role of insulin-like growth factors (IGF)-1.

T. Yoneda, K. Takeuchi, A. Tanaka, 2001, Medical science monitor : international medical journal of experimental and clinical research.

Aggravation by Paroxetine, a Selective Serotonin Reuptake Inhibitor, of Antral Lesions Generated by Nonsteroidal Anti-Inflammatory Drugs in Rats

K. Takeuchi, A. Tanaka, K. Amagase, 2011, Journal of Pharmacology and Experimental Therapeutics.

Delivery of Oxytocin to the Brain for the Treatment of Autism Spectrum Disorder by Nasal Application.

A. Kiriyama, H. Katsumi, A. Yamamoto, 2018, Molecular pharmaceutics.

Effect of cerebrospinal fluid circulation on nose-to-brain direct delivery and distribution of caffeine in rats.

K. Sugano, A. Tanaka, T. Sakane, 2020, Molecular pharmaceutics.

Transnasal delivery of the peptide agonist specific to Neuromedin-U receptor2 to the brain for the treatment of obesity.

K. Mori, K. Kangawa, A. Kiriyama, 2019, Molecular pharmaceutics.

Effects of no-releasing aspirin on functional and mucosal ulcerogenic responses in the rat stomach: Comparison with aspirin

K. Takeuchi, A. Tanaka, H. Yamamoto, 1998 .

Protection by aspirin of indomethacin-induced small intestinal damage in rats: mediation by salicylic acid

K. Takeuchi, H. Mizoguchi, A. Tanaka, 2001, Journal of Physiology-Paris.

COX and NOS isozymes involved in duodenal bicabonate response induced by mucosal acidificaton in rats

K. Takeuchi, A. Tanaka, S. Kagawa, 2001 .

Mechanisms Underlying the Gastroprotective Action of Glucocorticoids Released in Response to Ulcerogenic Stress Factors

K. Takeuchi, A. Tanaka, L. Filaretova, 2004, Annals of the New York Academy of Sciences.

Novel Strategy for the Systemic Delivery of Furosemide Based on a New Drug Transport Mechanism.

A. Kiriyama, H. Katsumi, A. Yamamoto, 2018, Biological & pharmaceutical bulletin.

Nasal Absorption of Macromolecules from Powder Formulations and Effects of Sodium Carboxymethyl Cellulose on Their Absorption

H. Katsumi, A. Yamamoto, A. Tanaka, 2016, PloS one.

COX inhibition and NSAID-induced gastric damage--roles in various pathogenic events.

K. Takeuchi, Y. Hayashi, A. Tanaka, 2005, Current Topics in Medicinal Chemistry.

A chemically stable peptide agonist to neuromedin U receptor type 2.

K. Mori, N. Minamino, K. Kangawa, 2020, Bioorganic & Medicinal Chemistry.

Discovery of a Human Neuromedin U Receptor 1-Selective Hexapeptide Agonist with Enhanced Serum Stability.

K. Mori, N. Minamino, K. Kangawa, 2017, Journal of medicinal chemistry.

Peroxynitrite treatment reduces adenosine uptake via the equilibrative nucleoside transporter in rat astrocytes

A. Tanaka, K. Nagasawa, S. Fujimoto, 2011, Neuroscience Letters.

Importance of the Direct Contact of Amorphous Solid Particles with the Surface of Monolayers for the Transepithelial Permeation of Curcumin.

H. Katsumi, A. Yamamoto, A. Tanaka, 2016, Molecular pharmaceutics.

Prostaglandin E(2)-activated housekeeping Cl(-) channels in the basolateral membrane of rat gastric parietal cells.

A. Ikari, A. Tanaka, H. Sakai, 1999, The Japanese Journal of Physiology.

Prostaglandin E2-Activated Housekeeping Cl- Channels in the Basolateral Membrane of Rat Gastric Parietal Cells

A. Ikari, Kanako Inoue, A. Tanaka, 1999 .

Gastrointestinal Protective Action of Prostaglandin E2 and EP Receptor Subtypes

K. Takeuchi, A. Tanaka, S. Kato, 2002 .

Comparison of Various Cell Lines and Three-Dimensional Mucociliary Tissue Model Systems to Estimate Drug Permeability Using an In Vitro Transport Study to Predict Nasal Drug Absorption in Rats

H. Katsumi, A. Yamamoto, A. Tanaka, 2020, Pharmaceutics.

Quantitative Estimation of the Effect of Nasal Mucociliary Function on in Vivo Absorption of Norfloxacin after Intranasal Administration to Rats.

A. Kiriyama, H. Katsumi, A. Yamamoto, 2018, Molecular pharmaceutics.

The relationship between in vivo nasal drug clearance and in vitro nasal mucociliary clearance: Application to the prediction of nasal drug absorption

A. Kiriyama, H. Katsumi, A. Yamamoto, 2018, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[Gastrointestinal cytoprotection by prostaglandin E and EP receptor subtypes].

K. Takeuchi, A. Tanaka, S. Kato, 2001, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Pathogenic importance of intestinal motility in indomethacin-induced small intestinal damage in rats

T. Kunikata, A. Tanaka, S. Kato, 2001 .

E type prostaglandin inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptors: A study using rats and knockout mice

K. Takeuchi, T. Kunikata, A. Tanaka, 2000 .

Roles of COX inhibition in pathogenesis of NSAID-induced small intestinal damage.

K. Takeuchi, H. Satoh, A. Tanaka, 2010, Clinica chimica acta; international journal of clinical chemistry.

Roles of Endogenous Prostaglandins and Cyclooxygenase Isozymes in Healing of Indomethacin-Induced Small Intestinal Lesions in Rats

K. Takeuchi, A. Tanaka, R. Ohno, 2006, Journal of Pharmacology and Experimental Therapeutics.

Aggravation by Paroxetine, a Selective Serotonin Reuptake Inhibitor, of Antral Lesions Generated by Nonsteroidal Anti-Inflammatory Drugs in Rats

K. Takeuchi, A. Tanaka, K. Amagase, 2011, Journal of Pharmacology and Experimental Therapeutics.

Importance of the Direct Contact of Amorphous Solid Particles with the Surface of Monolayers for the Transepithelial Permeation of Curcumin.

H. Katsumi, A. Yamamoto, A. Tanaka, 2016, Molecular pharmaceutics.

Novel strategy for improving the bioavailability of curcumin based on a new membrane transport mechanism that directly involves solid particles

A. Kiriyama, H. Katsumi, A. Yamamoto, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Prevention by Parenteral Aspirin of Indomethacin-Induced Gastric Lesions in Rats: Mediation by Salicylic Acid

K. Takeuchi, A. Tanaka, S. Kato, 2002, Digestive Diseases and Sciences.