Jian Yang

Jian Yang, Zhu Zhu, Jing Xiong, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor

Jian Yang, B. Yan, Ruitang Deng, 2011, British journal of pharmacology.

ANTI-INFLUENZA PRODRUG OSELTAMIVIR IS ACTIVATED BY CARBOXYLESTERASE HCE1 AND THE ACTIVATION IS INHIBITED BY ANTI-PLATELET AGENT CLOPIDOGREL

F. Akhlaghi, Jian Yang, B. Yan, 2006 .

Interleukin-6 Alters the Cellular Responsiveness to Clopidogrel, Irinotecan, and Oseltamivir by Suppressing the Expression of Carboxylesterases HCE1 and HCE2

Jian Yang, B. Yan, Xiulong Song, 2007, Molecular Pharmacology.

The Hypolipidemic Agent Guggulsterone Regulates the Expression of Human Bile Salt Export Pump: Dominance of Transactivation over Farsenoid X Receptor-Mediated Antagonism

Jian Yang, B. Yan, Ruitang Deng, 2007, Journal of Pharmacology and Experimental Therapeutics.

Oxysterol 22(R)-Hydroxycholesterol Induces the Expression of the Bile Salt Export Pump through Nuclear Receptor Farsenoid X Receptor but Not Liver X Receptor

Jian Yang, B. Yan, Ruitang Deng, 2006, Journal of Pharmacology and Experimental Therapeutics.

Down regulation of differentiated embryonic chondrocytes 1 (DEC1) is involved in 8-methoxypsoralen-induced apoptosis in HepG2 cells.

G. Hu, Jian Yang, Yan-Hui Peng, 2012, Toxicology.

Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway.

G. Hu, Jian Yang, B. Yan, 2011, Toxicology letters.

The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1.

Tao Xi, W. Luo, Jian Yang, 2016, Pharmacological research.

Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis

Jian Yang, B. Yan, Yichen Wu, 2023, The Journal of biological chemistry.

Interleukin-6 Induces DEC1, Promotes DEC1 Interaction with RXRα and Suppresses the Expression of PXR, CAR and Their Target Genes

W. Liu, G. Hu, Jian Yang, 2017, Front. Pharmacol..

Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes.

Tao Xi, G. Hu, Jian Yang, 2014, The international journal of biochemistry & cell biology.

DEC1 binding to the proximal promoter of CYP3A4 ascribes to the downregulation of CYP3A4 expression by IL-6 in primary human hepatocytes.

G. Hu, Jian Yang, B. Yan, 2012 .

MOL 36889 INTERLEUKIN-6 ALTERS THE CELLULAR RESPONSIVENESS TO CLOPIDOGREL , IRINOTECAN AND OSELTAMIVIR BY SUPPRESSING THE EXPRESSION OF CARBOXYLESTERASES HCE 1 AND HCE 2

Jian Yang, B. Yan, Xiulong Song, 2007 .

Gambogic acid suppresses cytochrome P450 3A4 by downregulating pregnane X receptor and up-regulating DEC1 in human hepatoma HepG2 cells

Q. Guo, G. Hu, Jian Yang, 2015 .

Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway

Ming Lu, G. Hu, Jian Yang, 2017, CNS neuroscience & therapeutics.

Timosaponin AIII Induces G2/M Arrest and Apoptosis in Breast Cancer by Activating the ATM/Chk2 and p38 MAPK Signaling Pathways

Q. Qi, Jian Yang, Yichen Wu, 2021, Frontiers in Pharmacology.

Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up‐regulating H‐Ras and N‐Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells

G. Hu, Jian Yang, Jing Xiong, 2016, Molecular carcinogenesis.

Curcumin Protects against 1-Methyl-4-phenylpyridinium Ion- and Lipopolysaccharide-Induced Cytotoxicities in the Mouse Mesencephalic Astrocyte via Inhibiting the Cytochrome P450 2E1

G. Hu, Jian Yang, Yan-Hui Peng, 2013, Evidence-based complementary and alternative medicine : eCAM.

17&bgr;‐estradiol suppresses carboxylesterases by activating c‐Jun/AP‐1 pathway in primary human and mouse hepatocytes

Jian Yang, B. Yan, Jing Xiong, 2018, European journal of pharmacology.

Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway

G. Hu, Jian Yang, Jing Xiong, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin.

G. Hu, Jian Yang, C. Xue, 2007, Life sciences.

DEC1 deficiency in accelerated osteopenia/osteoporosis.

H. Honda, Jian Yang, B. Yan, 2021, Metabolism: clinical and experimental.

[Effects of enalapril on plasma Ang II level and the expression of AT1 in blood vessel and kidney of type 2 diabetic rats].

G. Hu, Jian Yang, C. Xue, 2005, Yao xue xue bao = Acta pharmaceutica Sinica.

The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter

Y. Li, R. Deng, B. Yan, 2006, Oncogene.

Gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and -2

Q. Qi, G. Hu, Jian Yang, 2016, Xenobiotica; the fate of foreign compounds in biological systems.

Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes.

Tao Xi, G. Hu, Jian Yang, 2014, The international journal of biochemistry & cell biology.

Dexamethasone suppresses the expression of multiple rat carboxylesterases through transcriptional repression: evidence for an involvement of the glucocorticoid receptor.

Jian Yang, B. Yan, Dongfang Yang, 2008, Toxicology.

Fluoxetine Induces Hepatic Lipid Accumulation Via Both Promotion of the SREBP1c‐Related Lipogenesis and Reduction of Lipolysis in Primary Mouse Hepatocytes

G. Hu, Jian Yang, X. Feng, 2012, CNS neuroscience & therapeutics.

Glucose dominates the regulation of carboxylesterases induced by lipopolysaccharide or interleukin-6 in primary mouse hepatocytes.

G. Hu, Jian Yang, Jing Xiong, 2014, Life sciences.

Differentiated embryonic chondrocytes 1 expression of periodontal ligament tissue and gingival tissue in the patients with chronic periodontitis.

Haitao Yue, Jian Yang, Ruini Chen, 2015, Archives of oral biology.