V. Lamba

发表

The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

Wooin Lee, Erin G. Schuetz, Yusuke Inoue, 2003, Nature Medicine.

Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5

P. Watkins, E. Schuetz, P. Stewart, 2005, Clinical pharmacology and therapeutics.

Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics.

E. Schuetz, J. Lamba, V. Lamba, 2005, Current drug metabolism.

JPET # 69310 1 Expression of CAR splice variants in human tissues and their functional consequences

S. Strom, E. Schuetz, Yvonne S. Lin, 2004 .

Pharmacogenetic Pathway Analysis of Docetaxel Elimination

A. Wolff, J. Verweij, S. Marsh, 2009, Clinical pharmacology and therapeutics.

Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes.

J. Downing, S. Raimondi, D. Campana, 2011, Pharmacogenomics.

Reply to "genetic determinants of mycophenolate-related anemia and leukopenia after transplantation"

W. Guan, A. Israni, B. Julian, 2012 .

PharmGKB summary: mycophenolic acid pathway

R. Altman, K. Sangkuhl, T. Klein, 2014, Pharmacogenetics and genomics.

Genetic Determinants of Mycophenolate-Related Anemia and Leukopenia After Transplantation

A. Israni, B. Julian, D. Schladt, 2011, Transplantation.

Novel Polymorphisms Associated With Tacrolimus Trough Concentrations: Results From a Multicenter Kidney Transplant Consortium

A. Israni, B. Julian, D. Schladt, 2011, Transplantation.

STAT5A and STAT5B have opposite correlations with drug response gene expression.

F. Liang, V. Lamba, B. Jia, 2016, Biochemical and biophysical research communications.

Identification of suitable reference genes for hepatic microRNA quantitation

W. Guan, Y. Ghodke-Puranik, J. Lamba, 2014, BMC Research Notes.

Genetic polymorphism of CYP2D6 in North Indian subjects

K. K. Kohli, J. Dilawari, J. Lamba, 1998, European Journal of Clinical Pharmacology.

Expression of Constitutive Androstane Receptor Splice Variants in Human Tissues and Their Functional Consequences

S. Strom, E. Schuetz, Yvonne S. Lin, 2004, Journal of Pharmacology and Experimental Therapeutics.

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.

S. Strom, E. Schuetz, J. Davila, 2004, Toxicology and applied pharmacology.

microRNA-34a is associated with expression of key hepatic transcription factors and cytochromes P450.

W. Guan, V. Lamba, Y. Ghodke, 2014, Biochemical and biophysical research communications.

MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype

Cheng Cheng, P. Watkins, S. Strom, 2006, Clinical pharmacology and therapeutics.

Genetic and Clinical Determinants of Early, Acute Calcineurin Inhibitor-Related Nephrotoxicity: Results From a Kidney Transplant Consortium

A. Israni, A. Matas, W. Oetting, 2012, Transplantation.

Single-Nucleotide Polymorphisms, Acute Rejection, and Severity of Tubulitis in Kidney Transplantation, Accounting for Center-to-Center Variation

W. Guan, Jinbo Chen, A. Israni, 2010, Transplantation.

Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression

B. Ring, S. Wrighton, S. Strom, 2003, Journal of Pharmacology and Experimental Therapeutics.

Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans

M. Ratain, S. Hanauer, E. Schuetz, 2009, The Pharmacogenomics Journal.

Identification of suitable reference genes for hepatic microRNA quantitation

W. Guan, Y. Ghodke-Puranik, J. Lamba, 2014, BMC Research Notes.

MicroRNA–mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients

S. Pounds, Xueyuan Cao, J. Lamba, 2016, Front. Pharmacol..

Learning gene regulatory networks from next generation sequencing data

Faming Liang, Guanghua Xiao, Bochao Jia, 2017, Biometrics.

Cytochrome P450 2B6*5 Increases Relapse after Cyclophosphamide-Containing Conditioning and Autologous Transplantation for Lymphoma.

D. Weisdorf, V. Bachanova, J. Lamba, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

ADME transcriptome in Hispanic versus White donor livers: Evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics

D. Finkelstein, S. Strom, E. Schuetz, 2006, Xenobiotica; the fate of foreign compounds in biological systems.

Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression

S. Strom, E. Schuetz, J. Panetta, 2010, Journal of Pharmacology and Experimental Therapeutics.

Genetic Predictors of Interindividual Variability in Hepatic

S. Strom, E. Schuetz, J. Panetta, 2010 .

Genetic predictors of inter-individual variability in hepatic CYP 3 A 4 expression

S. Strom, E. Schuetz, J. Panetta, 2009 .

Novel Single Nucleotide Polymorphisms in the Promoter and Intron 1 of Human Pregnane X Receptor/NR1I2 and Their Association with CYP3A4 Expression

S. Strom, E. Schuetz, R. Venkataramanan, 2008, Drug Metabolism and Disposition.

PharmGKB summary: very important pharmacogene information for CYP2B6

R. Altman, C. Thorn, T. Klein, 2010, Pharmacogenetics and genomics.

Using PharmGKB to train text mining approaches for identifying potential gene targets for pharmacogenomic studies

Bridget T. McInnes, Serguei V. S. Pakhomov, Genevieve B. Melton, 2012, J. Biomed. Informatics.