T. Niwa

发表

Impact of Drug Transporter Studies on Drug Discovery and Development

Yuichi Sugiyama, Y. Sugiyama, Naomi Mizuno, 2003, Pharmacological Reviews.

Impaired renal excretion of 6-hydroxy-5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl) benzothiazole (E3040) sulfate in breast cancer resistance protein (BCRP1/ABCG2) knockout mice.

H. Kusuhara, Y. Sugiyama, K. Takeuchi, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population.

T. Kuwabara, T. Izumi, T. Kawashiro, 2004, Drug metabolism and pharmacokinetics.

Evaluation of the Role of Breast Cancer Resistance Protein (BCRP/ABCG2) and Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) in The Urinary Excretion of Sulfate and Glucuronide Metabolites of Edaravone (MCI-186; 3-Methyl-1-phenyl-2-pyrazolin-5-one)

Yuichi Sugiyama, Hiroyuki Kusuhara, H. Kusuhara, 2007, Drug Metabolism and Disposition.

Human Organic Anion Transporters 1 (hOAT1/SLC22A6) and 3 (hOAT3/SLC22A8) Transport Edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one) and Its Sulfate Conjugate

H. Kusuhara, Y. Sugiyama, Y. Iwase, 2007, Drug Metabolism and Disposition.

[Drug transporter studies in drug discovery and development].

Naomi Mizuno, T. Niwa, 2005, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Human organic anion transporters 1 (hOAT1/ ) and 3 (hOAT3/ ) transport edaravone (MCI-186; and its sulfate conjugate.

H. Kusuhara, Y. Sugiyama, Y. Iwase, 2007 .

CYP3A4*16 and CYP3A4*18 Alleles Found in East Asians Exhibit Differential Catalytic Activities for Seven CYP3A4 Substrate Drugs

M. Naito, Yoshiro Saito, M. Tohkin, 2010, Drug Metabolism and Disposition.

AUTOINDUCTION OF MKC-963 [(R)-1-(1-CYCLOHEXYLETHYLAMINO)-4-PHENYLPHTHALAZINE] METABOLISM IN HEALTHY VOLUNTEERS AND ITS RETROSPECTIVE EVALUATION USING PRIMARY HUMAN HEPATOCYTES AND CDNA-EXPRESSED ENZYMES

Toshiyuki Shimizu, Kaoru Kobayashi, K. Chiba, 2006, Drug Metabolism and Disposition.

Histone Deacetylase Inhibitor Valproic Acid Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells

Takayoshi Suzuki, N. Miyata, Katsunori Nakamura, 2014, PloS one.

Safety Assessment, In Vitro and In Vivo, and Pharmacokinetics of Emivirine, a Potent and Selective Nonnucleoside Reverse Transcriptase Inhibitor of Human Immunodeficiency Virus Type 1

K. Borroto-Esoda, G. Painter, M. Yamamoto, 2000, Antimicrobial Agents and Chemotherapy.

Generation of Enterocyte-Like Cells with Pharmacokinetic Functions from Human Induced Pluripotent Stem Cells Using Small-Molecule Compounds

Katsunori Nakamura, T. Matsunaga, K. Kurose, 2015, Drug Metabolism and Disposition.

6-(4-Pyridyl)pyrimidin-4(3H)-ones as CNS penetrant glycogen synthase kinase-3β inhibitors.

A. Shoda, Shinji Tanaka, H. Kubodera, 2013, Bioorganic & medicinal chemistry letters.

Kinetic Analysis of the Disposition of Insulin-Like Growth Factor 1 in Healthy Volunteers

Y. Sugiyama, Y. Kato, A. Urae, 2001, Pharmaceutical Research.

Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into enterocytes.

Katsunori Nakamura, T. Matsunaga, T. Niwa, 2016, Drug metabolism and pharmacokinetics.

Functional characterization of CYP3A4.16: Catalytic activities toward midazolam and carbamazepine

Yoshiro Saito, J. Sawada, S. Narimatsu, 2009, Xenobiotica; the fate of foreign compounds in biological systems.

Hepatocyte growth factor stimulates liver regeneration and elevates blood protein level in normal and partially hepatectomized rats.

T. Niwa, T. Niwa, K. Sudo, 1995, Journal of biochemistry.

Generation of Enterocyte-Like Cells with Pharmacokinetic Functions from Human Induced Pluripotent Stem Cells Using Small-Molecule Compounds

Katsunori Nakamura, T. Matsunaga, K. Kurose, 2015, Drug Metabolism and Disposition.