Yuxin Li

The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes.

B. Yan, Xiulong Song, M. Xie, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Simultaneous Substitution of Phenylalanine-305 and Aspartate-318 of Rat Pregnane X Receptor with the Corresponding Human Residues Abolishes the Ability to Transactivate the CYP3A23 Promoter

B. Yan, Xiulong Song, Yuxin Li, 2005, Journal of Pharmacology and Experimental Therapeutics.

DEC1 Negatively Regulates the Expression of DEC2 through Binding to the E-box in the Proximal Promoter*

Y. Wan, B. Yan, Xiulong Song, 2003, The Journal of Biological Chemistry.

Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation.

Y. Wan, Shujun Ge, B. Yan, 2002, The Biochemical journal.

Intramolecular disulfide bonds are required for folding hydrolase B into a catalytically active conformation but not for maintaining it during catalysis.

B. Yan, Xiulong Song, Yuxin Li, 2004, Biochemical and biophysical research communications.

DNA binding, but not interaction with Bmal1, is responsible for DEC1-mediated transcription regulation of the circadian gene mPer1.

B. Yan, Xiulong Song, Yuxin Li, 2004, The Biochemical journal.

Clofibrate and perfluorodecanoate both upregulate the expression of the pregnane X receptor but oppositely affect its ligand-dependent induction on cytochrome P450 3A23.

C. Chichester, B. Yan, Xiulong Song, 2005, Biochemical pharmacology.

The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter

Y. Li, R. Deng, B. Yan, 2006, Oncogene.