J. Wen

发表

[Gene polymorphism of CYP450 2C9 and VKORC1 in Chinese population and their relationships to the maintaining dosage of warfarin].

Mei Han, Ya-nan Zhang, W. Cui, 2010, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

miR‐146a and Krüppel‐like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation

Mei Han, Bin Zheng, J. Wen, 2011, EMBO reports.

miR-146 a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation

Mei Han, Bin Zheng, J. Wen, 2010 .

[Effects of Astragalus and saponins of Panax notoginseng on MMP-9 in patients with type 2 diabetic macroangiopathy].

Mei Han, J. Wen, Kuan-zhi Liu, 2004, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

Livin/ML-IAP as a new target for cancer treatment.

B. Liu, Ling Wang, J. Wen, 2007, Cancer letters.

Localization and function of KLF4 in cytoplasm of vascular smooth muscle cell.

Xin-hua Zhang, Bin Zheng, J. Wen, 2013, Biochemical and biophysical research communications.

Role of Krüppel‐like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells

Mei Han, Bin Zheng, J. Wen, 2010, IUBMB life.

Serum deprivation results in redifferentiation of human umbilical vascular smooth muscle cells.

Chunxiang Zhang, Mei Han, Yun-hui Cheng, 2006, American journal of physiology. Cell physiology.

Kruppel-like factor 4 is required for the expression of vascular smooth muscle cell differentiation marker genes induced by all-trans retinoic acid.

Mei Han, J. Wen, Chao Wang, 2008, Journal of biochemistry.

Regulatory crosstalk between KLF5, miR-29a and Fbw7/CDC4 cooperatively promotes atherosclerotic development.

Xin-hua Zhang, Hong Zhang, Bin Zheng, 2018, Biochimica et biophysica acta. Molecular basis of disease.

Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter

Ruonan Zhang, M. He, Bin Zheng, 2014, Bioscience reports.

Roles of LIM proteins in cardiac hypertrophy.

Mei Han, Bin Zheng, J. Wen, 2005, Future cardiology.

Regulatory Factors Involved in Cardiogenesis

Mei Han, Bin Zheng, J. Wen, 2003, Biochemistry (Moscow).

Tongxinluo protects against hypoxia-induced breakdown of the endothelial barrier through inducing tight junction protein expression

Xin-hua Zhang, Bin Zheng, J. Wen, 2016 .

Flavonoids from Inula britannica L. inhibit injury-induced neointimal formation by suppressing oxidative-stress generation.

Mei Han, Bin Zheng, J. Wen, 2009, Journal of ethnopharmacology.

HDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs

Mei Han, Bin Zheng, J. Wen, 2011, Cell Research.

Baicalin inhibits PDGF-BB-stimulated vascular smooth muscle cell proliferation through suppressing PDGFRβ-ERK signaling and increase in p27 accumulation and prevents injury-induced neointimal hyperplasia

Mei Han, Z. Jia, Yiling Wu, 2011, Cell Research.

miR-155 down-regulation protects the heart from hypoxic damage by activating fructose metabolism in cardiac fibroblasts

Hong Zhang, J. Wen, Tian-ying Zhai, 2021, Journal of advanced research.

Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission

Toru Suzuki, Bin Zheng, J. Wen, 2020, PLoS biology.

eIF5a reduction via decreased Klf5 leads to cell senescence by mitochondrial fission in VSMCs

Toru Suzuki, Bin Zheng, J. Wen, 2019, bioRxiv.

Polymorphisms of the ICAM-1 exon 6 (E469K) are associated with differentiation of colorectal cancer

B. Liu, Mei Han, J. Wen, 2009, Journal of experimental & clinical cancer research : CR.

umbilical vascular smooth muscle cells Serum deprivation results in redifferentiation of human

Chunxiang Zhang, Mei Han, Yun-hui Cheng, 2016 .

ATRA activates and PDGF‐BB represses the SM22α promoter through KLF4 binding to or dissociating from its cis‐DNA elements

Mei Han, Bin Zheng, J. Wen, 2011, Cardiovascular research.

Synthetic retinoid Am80 inhibits interaction of KLF5 with RARα through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells

Mei Han, Bin Zheng, J. Wen, 2009, FEBS letters.

Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose.

Bin Zheng, J. Wen, Lihui Zhang, 2020, Journal of ethnopharmacology.

Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages.

Bin Zheng, J. Wen, Wen-Yan Jiang, 2016, American journal of translational research.

hhLIM is a novel F‐actin binding protein involved in actin cytoskeleton remodeling

Mei Han, Bin Zheng, J. Wen, 2008, The FEBS journal.

Blockade of integrin β3–FAK signaling pathway activated by osteopontin inhibits neointimal formation after balloon injury

Mei Han, Bin Zheng, J. Wen, 2007 .

SUMOylation of KLF4 acts as a switch in transcriptional programs that control VSMC proliferation.

Guo-liang Zhang, Bin Zheng, J. Wen, 2016, Experimental cell research.

Exosome-Mediated miR-155 Transfer from Smooth Muscle Cells to Endothelial Cells Induces Endothelial Injury and Promotes Atherosclerosis.

Toru Suzuki, Hong Zhang, Bin Zheng, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration.

Man-Li Zhang, Bin Zheng, J. Wen, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Chinese medicine Tongxinluo increases tight junction protein levels by inducing KLF5 expression in microvascular endothelial cells

Ruonan Zhang, J. Wen, Cui-ying Zheng, 2015, Cell biochemistry and function.

TMEM16A and Myocardin Form a Positive Feedback Loop That Is Disrupted by KLF5 During Ang II–Induced Vascular Remodeling

Xuan Zhang, Ruonan Zhang, M. He, 2015, Hypertension.

Synthetic retinoid Am 80 upregulates apelin expression by promoting interaction of RAR α with KLF 5 and Sp 1 in vascular smooth muscle cells

Bin Zheng, J. Wen, Yan Liu, 2013 .

Synthetic retinoid Am80 up-regulates apelin expression by promoting interaction of RARα with KLF5 and Sp1 in vascular smooth muscle cells.

Bin Zheng, J. Wen, Yan Liu, 2013, The Biochemical journal.

1, 25(OH)2D3-induced interaction of vitamin D receptor with p50 subunit of NF-κB suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation.

Ruonan Zhang, Bin Zheng, J. Wen, 2017, Biochemical and biophysical research communications.

Krüppel-like Factor 4 Inhibits Proliferation by Platelet-derived Growth Factor Receptor β-mediated, Not by Retinoic Acid Receptor α-mediated, Phosphatidylinositol 3-Kinase and ERK Signaling in Vascular Smooth Muscle Cells*

Mei Han, M. Bernier, M. He, 2009, The Journal of Biological Chemistry.

Krüppel-like factor (KLF) 5 mediates cyclin D1 expression and cell proliferation via interaction with c-Jun in Ang II-induced VSMCs

Mei Han, Bin Zheng, J. Wen, 2010, Acta Pharmacologica Sinica.

Salvianolic acid B inhibits Ang II-induced VSMC proliferation in vitro and intimal hyperplasia in vivo by downregulating miR-146a expression.

Bin Zheng, J. Wen, Xin‐hua Zhang, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Novel insight into Y‐box binding protein 1 in the regulation of vascular smooth muscle cell proliferation through targeting GC box‐dependent genes

Bin Zheng, J. Wen, Yong-hui Li, 2013, FEBS letters.

KLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells

Bin Zheng, J. Wen, Hui-jing Shi, 2012, Molecular and Cellular Biochemistry.

All-trans retinoic acid increases KLF4 acetylation by inducing HDAC2 phosphorylation and its dissociation from KLF4 in vascular smooth muscle cells.

Mei Han, Bin Zheng, J. Wen, 2009, Biochemical and biophysical research communications.

Synergistic co‐operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II‐induced angiotensinogen gene activation in vascular smooth muscle cells

Mei Han, L. Nie, Ai-Ying Li, 2009, The FEBS journal.

CDK13 upregulation-induced formation of the positive feedback loop among circCDK13, miR-212-5p/miR-449a and E2F5 contributes to prostate carcinogenesis

Hong Zhang, J. Wen, Bei Shi, 2021, Journal of experimental & clinical cancer research : CR.

Tongxinluo inhibits vascular inflammation and neointimal hyperplasia through blockade of the positive feedback loop between miR-155 and TNF-α.

Ruonan Zhang, Bin Zheng, J. Wen, 2014, American journal of physiology. Heart and circulatory physiology.

hhLIM protein is involved in cardiac hypertrophy.

Mei Han, Bin Zheng, J. Wen, 2004, Biochimica et biophysica acta.

Expression of HSG is essential for mouse blastocyst formation.

Mei Han, J. Wen, Xiuying Huang, 2005, Biochemical and biophysical research communications.

Nuclear actin and actin‐binding proteins in the regulation of transcription and gene expression

Mei Han, M. Bernier, Bin Zheng, 2009, The FEBS journal.

Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis.

Mei Han, J. Wen, P. Zhao, 2005, World journal of gastroenterology.

hhLIM is involved in cardiomyogenesis of embryonic stem cells

Mei Han, Bin Zheng, J. Wen, 2006, Biochemistry (Moscow).

Chinese medicine Tongxinluo reduces atherosclerotic lesion by attenuating oxidative stress and inflammation in microvascular endothelial cells.

Ruonan Zhang, M. He, Bin Zheng, 2015, International journal of clinical and experimental pathology.

Roscovitine inhibits ERK1/2 activation induced by angiotensin II in vascular smooth muscle cells

Mei Han, Ai-Ying Li, Bin Zheng, 2008, FEBS letters.

Osteopontin stimulates vascular smooth muscle cell migration by inducing FAK phosphorylation and ILK dephosphorylation.

Mei Han, Ai-Ying Li, J. Wen, 2007, Biochemical and biophysical research communications.

Retinoic Acid Receptor α Mediates All-trans-retinoic Acid-induced Klf4 Gene Expression by Regulating Klf4 Promoter Activity in Vascular Smooth Muscle Cells*

Bin Zheng, J. Wen, Jian-Hong Shi, 2012, The Journal of Biological Chemistry.

TGF-&bgr;1 Downregulates AT1 Receptor Expression via PKC-&dgr;-Mediated Sp1 Dissociation From KLF4 and Smad-Mediated PPAR-&ggr; Association With KLF4

Bin Zheng, J. Wen, Xin‐hua Zhang, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Acetylbritannilactone suppresses lipopolysaccharide-induced vascular smooth muscle cell inflammatory response.

Mei Han, Bin Zheng, J. Wen, 2007, European journal of pharmacology.

Disturbing NLRP3 acetylation and inflammasome assembly inhibits androgen receptor‐promoted inflammatory responses and prostate cancer progression

J. Wen, Bei Shi, Chang-bao Qu, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

KLF4 mediates the link between TGF‐β1‐induced gene transcription and H3 acetylation in vascular smooth muscle cells

M. He, Bin Zheng, J. Wen, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

PPAR-γ agonist stabilizes KLF4 protein via activating Akt signaling and reducing KLF4 ubiquitination.

M. He, Bin Zheng, J. Wen, 2014, Biochemical and biophysical research communications.

Human heart LIM protein activates atrial-natriuretic-factor gene expression by interacting with the cardiac-restricted transcription factor Nkx2.5.

Mei Han, Bin Zheng, J. Wen, 2008, The Biochemical journal.

Acetylbritannilatone suppresses NO and PGE2 synthesis in RAW 264.7 macrophages through the inhibition of iNOS and COX-2 gene expression.

Mei Han, Bin Zheng, J. Wen, 2004, Life sciences.

Tanshinone ⅡA inhibits VSMC inflammation and proliferation in vivo and in vitro by downregulating miR-712-5p expression.

Bin Zheng, J. Wen, Tian-Rui Wang, 2020, European journal of pharmacology.

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells

Huirong Liu, Mingming Zhao, Lemin Zheng, 2022, Communications Biology.

Acetylbritannilactone suppresses growth via upregulation of krüppel-like transcription factor 4 expression in HT-29 colorectal cancer cells.

B. Liu, Mei Han, Jun-jie Wang, 2011, Oncology reports.

Acetylbritannilactone Inhibits Neointimal Hyperplasia after Balloon Injury of Rat Artery by Suppressing Nuclear Factor-κB Activation

B. Liu, Mei Han, J. Wen, 2008, Journal of Pharmacology and Experimental Therapeutics.

Salvia miltiorrhiza-Derived Sal-miR-58 Induces Autophagy and Attenuates Inflammation in Vascular Smooth Muscle Cells

Bin Zheng, J. Wen, Zhan Yang, 2020, Molecular therapy. Nucleic acids.

Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis

Bin Zheng, J. Wen, Zhan Yang, 2020, Theranostics.

Downregulation of lncRNA MIR181A2HG by high glucose impairs vascular endothelial cell proliferation and migration through the dysregulation of the miRNAs/AKT2 axis

Bin Zheng, J. Wen, Shaohua Wang, 2021, International journal of molecular medicine.

ABL-N-induced apoptosis in human breast cancer cells is partially mediated by c-Jun NH2-terminal kinase activation

B. Liu, Mei Han, Jun-jie Wang, 2010, Breast Cancer Research.

Morin Inhibits Proliferation and Induces Apoptosis by Modulating the miR-188-5p/PTEN/AKT Regulatory Pathway in CML Cells

Ling-ling Jiang, J. Wen, Jian-Min Luo, 2019, Molecular Cancer Therapeutics.

A Novel Regulatory Mechanism of Smooth Muscle &agr;-Actin Expression by NRG-1/circACTA2/miR-548f-5p Axis

Toru Suzuki, Man-Li Zhang, Bin Zheng, 2017, Circulation research.

[Determination of osteopontin at trace levels by non-gel sieving capillary electrophoresis].

Mei Han, J. Wen, Jingshan Zhao, 2005, Se pu = Chinese journal of chromatography.

[Application of genomics and proteomics in study of traditional Chinese medicine].

Mei Han, J. Wen, 2004, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

[Supplementing Qi and activating blood circulation in gene regulation of vascular smooth muscle cells].

Mei Han, J. Wen, 2003, Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.

Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway

Man-Li Zhang, Bin Zheng, J. Wen, 2018, Oncogene.

17β-Estradiol Inhibits Proliferation and Oxidative Stress in Vascular Smooth Muscle Cells by Upregulating BHLHE40 Expression

Man-Li Zhang, Bin Zheng, J. Wen, 2021, Frontiers in Cardiovascular Medicine.

miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells.

Ruonan Zhang, M. He, Bin Zheng, 2015, Biochimica et biophysica acta.

SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm

Hong Zhang, J. Wen, Bei Shi, 2023, Cell Death & Disease.

Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cells.

Mei Han, M. He, Bin Zheng, 2009, Journal of biochemistry.

Blockade of the Ras–Extracellular Signal–Regulated Kinase 1/2 Pathway Is Involved in Smooth Muscle 22&agr;–Mediated Suppression of Vascular Smooth Muscle Cell Proliferation and Neointima Hyperplasia

Mei Han, M. McNutt, Bin Zheng, 2010, Arteriosclerosis, thrombosis, and vascular biology.

miR-200c-SUMOylated KLF4 feedback loop acts as a switch in transcriptional programs that control VSMC proliferation.

Toru Suzuki, M. Bernier, Bin Zheng, 2015, Journal of molecular and cellular cardiology.

Krüppel-like factor 4 interacts with p300 to activate mitofusin 2 gene expression induced by all-trans retinoic acid in VSMCs

Mei Han, Rui Zhang, Bin Zheng, 2010, Acta Pharmacologica Sinica.

Smooth muscle 22 alpha maintains the differentiated phenotype of vascular smooth muscle cells by inducing filamentous actin bundling.

Mei Han, Yun-hui Cheng, Bin Zheng, 2009, Life sciences.

Oxidative Stress Induces Neuronal Apoptosis Through Suppressing Transcription Factor EB Phosphorylation at Ser467

Zhixue Liu, Q. Su, Bin Zheng, 2018, Cellular Physiology and Biochemistry.

Blockade of integrin beta3-FAK signaling pathway activated by osteopontin inhibits neointimal formation after balloon injury.

Mei Han, Bin Zheng, J. Wen, 2007, Cardiovascular pathology.

Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel

Man-Li Zhang, Bin Zheng, J. Wen, 2017, Journal of experimental & clinical cancer research : CR.

Supplemental Experimental Procedures Microarray

Man-Li Zhang, Bin Zheng, J. Wen, 2018 .

Silencing of miR-193a-5p increases the chemosensitivity of prostate cancer cells to docetaxel

Man-Li Zhang, Bin Zheng, J. Wen, 2017, Journal of Experimental & Clinical Cancer Research.

circACTA2 mediates Ang II-induced VSMC senescence by modulation of the interaction of ILF3 with CDK4 mRNA

Hong Zhang, Bin Zheng, J. Wen, 2021, Aging.

Inhibition of KLF5–Myo9b–RhoA Pathway–Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm

Toru Suzuki, Ruonan Zhang, Bin Zheng, 2017, Circulation research.

Krüppel-like Factor 4 Promotes Differentiation by Transforming Growth Factor-β Receptor-mediated Smad and p38 MAPK Signaling in Vascular Smooth Muscle Cells*

Mei Han, Rui Zhang, M. Bernier, 2010, The Journal of Biological Chemistry.

KLF5 and hhLIM cooperatively promote proliferation of vascular smooth muscle cells

Bin Zheng, J. Wen, Yan Liu, 2012, Molecular and Cellular Biochemistry.

Mei Han, Z. Jia, Yiling Wu, 2010, Cell Research.

1,6-O,O-diacetylbritannilactones inhibits IkappaB kinase beta-dependent NF-kappaB activation.

Mei Han, Bin Zheng, J. Wen, 2009, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Flavonoids from Inula britannica reduces oxidative stress through inhibiting expression and phosphorylation of p47phox in VSMCs

Mei Han, Bin Zheng, J. Wen, 2011, Pharmaceutical biology.

Comparative Study of Induction of iNOS mRNA Expression in Vascular Cells of Different Species

J. Wen, M. Han, 2000, Biochemistry (Moscow).

miR‐29a regulates vascular neointimal hyperplasia by targeting YY1

Bin Zheng, J. Wen, Chan-juan Nie, 2017, Cell proliferation.

Human heart LIM protein has transcription activation ability related to LIM domain 1

Mei Han, Bin Zheng, J. Wen, 2008, Biochemistry (Moscow).

[Effect of bushen shengxue recipe on EPO gene expression of chronic renal insufficiency anemia in rats].

E. Li, J. Wen, N. Qu, 1995, Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.

Down-regulation of the Smad signaling by circZBTB46 via the Smad2-PDLIM5 axis to inhibit type I collagen expression.

Hong Zhang, Bin Zheng, J. Wen, 2023, Journal of geriatric cardiology : JGC.

Celecoxib and acetylbritannilactone interact synergistically to suppress breast cancer cell growth via COX-2-dependent and -independent mechanisms

Mei Han, J. Wen, J. Wang, 2011, Cell Death and Disease.

Exosomes‐transferred LINC00668 Contributes to Thrombosis by Promoting NETs Formation in Inflammatory Bowel Disease

Bin Zheng, J. Wen, Dong Ma, 2023, Advanced science.

Acetylbritannilactone induces G1 arrest and apoptosis in vascular smooth muscle cells.

B. Liu, Mei Han, Jun-jie Wang, 2011, International journal of cardiology.

Chinese medicine Tongxinluo increases tight junction protein levels by inducing KLF5 expression in microvascular endothelial cells

Ruonan Zhang, J. Wen, Cui-ying Zheng, 2015, Cell biochemistry and function.

Localization and function of KLF4 in cytoplasm of vascular smooth muscle cell.

Bin Zheng, J. Wen, Yan Liu, 2013, Biochemical and biophysical research communications.

circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells

Hong Zhang, Bin Zheng, J. Wen, 2023, Cellular and Molecular Life Sciences.

Novel insight into Y‐box binding protein 1 in the regulation of vascular smooth muscle cell proliferation through targeting GC box‐dependent genes

Bin Zheng, J. Wen, Yong-hui Li, 2013, FEBS letters.

Comparison of gene expression patterns and migration capability at quiescent and proliferating vascular smooth muscle cells stimulated by cytokines.

Mei Han, Bin Zheng, J. Wen, 2002, Life Science.

Hyperplasia suppressor gene associates with smooth muscle α-actin and is involved in the redifferentiation of vascular smooth muscle cells

Mei Han, Bin Zheng, J. Wen, 2006, Heart and Vessels.

Nanoparticles targeting OPN loaded with BY1 inhibits vascular restenosis by inducing FTH1-dependent ferroptosis in vascular smooth muscle cells.

J. Wen, Yu Zhang, Han Wu, 2024, Biomaterials.

hhLIM is a novel F‐actin binding protein involved in actin cytoskeleton remodeling

Mei Han, Bin Zheng, J. Wen, 2008, The FEBS journal.

hhLIM Is a Novel F‐Actin Binding Protein Involved in Actin Cytoskeleton Remodeling

Mei Han, Bin Zheng, J. Wen, 2008 .

Synthetic retinoid Am80 inhibits interaction of KLF5 with RAR¦Á through inducing KLF5 dephosphorylation mediated by the PI3K/Akt signaling in vascular smooth muscle cells

Mei Han, Bin Zheng, J. Wen, 2009 .