C. James

发表

Biliary elimination of cyclophosphamide in man

J. Dooley, R. Stuart-Harris, H. Rogers, 2004, Cancer Chemotherapy and Pharmacology.

Critical review of p38 MAP kinase inhibitors: a bioanalytical perspective.

C. James, P. Wong, Faye Hsieh, 2012, Bioanalysis.

Simultaneous determination of a p38 MAP kinase inhibitor and its amide hydrolyzed metabolite in Cynomolgus monkey plasma by LC-MS/MS, and its application to a toxicokinetic study.

A. Akrami, C. James, P. Wong, 2011, Journal of pharmaceutical and biomedical analysis.

Direct Quantitative Analysis of a 20 kDa PEGylated Human Calcitonin Gene Peptide Antagonist in Cynomolgus Monkey Serum Using In-Source CID and UPLC-MS/MS

L. Miranda, M. Rose, C. James, 2011, Journal of the American Society for Mass Spectrometry.

LC–MS/MS Bioanalytical Method Development Strategy for Therapeutic Monoclonal Antibodies in Preclinical Studies

T. Heath, C. James, Hongyan Li, 2017 .

The influence of cimetidine on debrisoquine 4-hydroxylation in extensive metabolizers

P. Philip, H. Rogers, C. James, 2004, European Journal of Clinical Pharmacology.

Serial sampling in the mouse in support of pharmacokinetic studies with turbulent flow chromatography and tandem mass spectrometry

S. Rolando, B. Clark, C. James, 2002 .

Evaluation of matrix microsampling methods for therapeutic drug candidate quantification in discovery-stage rodent pharmacokinetic studies.

M. Retter, C. James, K. Salyers, 2014, Bioanalysis.

Increasing efficiency for dried blood spot analysis: prospects for automation and simplified sample analysis.

C. James, P. Wong, Roger Pham, 2010, Bioanalysis.

LC‐MS Bioanalysis of Peptides and Polypeptides

C. James, Hongyan Li, 2013 .

Rapid method for the determination of ifosfamide and cyclophosphamide in plasma by high-performance liquid chromatography with solid-phase extraction.

C. James, L. C. Burton, 1988, Journal of chromatography.

Evaluation and Elimination of Matrix Effects in LC‐MS Bioanalysis

C. James, B. Bruenner, 2013 .

Ion-suppression effects in liquid chromatography-tandem mass spectrometry due to a formulation agent, a case study in drug discovery bioanalysis.

D. Fraier, C. James, P. Larger, 2005, Journal of pharmaceutical and biomedical analysis.

Development of a method for the determination of glycine in human cerebrospinal fluid using pre-column derivatization and LC-MS/MS.

Xiaochun Zhu, M. Rose, C. James, 2011, Journal of pharmaceutical and biomedical analysis.

LC-MS-MS determination of exemestane in human plasma with heated nebulizer interface following solid-phase extraction in the 96 well plate format.

C. James, V. Cenacchi, J. Long, 2000, Journal of pharmaceutical and biomedical analysis.

Determination of MAG-camptothecin, a new polymer-bound camptothecin derivative, and free camptothecin in dog plasma by HPLC with fluorimetric detection.

D. Fraier, C. James, E. Frigerio, 2000, Journal of pharmaceutical and biomedical analysis.

Fast turnaround bioanalysis in discovery and early clinical development

K. Munesada, C. James, J. Long, 2002 .

Special problems associated with the bioanalysis of anti-cancer drugs

K. Munesada, C. James, J. Long, 2002 .

Determination of prednisolone in human adipose tissue incubation medium using LC-MS/MS to support the measurement of 11beta-hydroxysteroid dehydrogenase activity.

M. Emery, I. McCaffery, J. Rossi, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Hydrophilic interaction liquid chromatography-APCI-mass spectrometry determination of 5-fluorouracil in plasma and tissues.

C. James, M. Breda, R. Pisano, 2005, Journal of pharmaceutical and biomedical analysis.

Quantitative determination of paclitaxel in human plasma using semi-automated liquid-liquid extraction in conjunction with liquid chromatography/tandem mass spectrometry.

C. James, G. Basileo, M. Breda, 2003, Journal of pharmaceutical and biomedical analysis.

Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing

Hossein Salimi-Moosavi, Christopher A. James, Jean W. Lee, 2012, The AAPS Journal.

Development and validation of a method for the determination of a therapeutic peptide with affinity for the human B1 receptor in human plasma using HPLC-MS/MS.

M. Rose, C. James, J. R. Holder, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Quantitation of SU11248, an oral multi-target tyrosine kinase inhibitor, and its metabolite in monkey tissues by liquid chromatograph with tandem mass spectrometry following semi-automated liquid–liquid extraction

C. James, C. Ye, Q. Zhang, 2004 .

LC-MS-MS determination of nemorubicin (methoxymorpholinyldoxorubicin, PNU-152243A) and its 13-OH metabolite (PNU-155051A) in human plasma.

D. Fraier, C. James, E. Frigerio, 2002, Journal of pharmaceutical and biomedical analysis.

Estimation of doxorubicin and doxorubicinol by high-performance liquid chromatography and advanced automated sample processor.

N. Dobbs, C. James, 1987, Journal of chromatography.

Analysis of Drugs and Metabolites in Tissues and Other Solid Matrices

C. James, E. Frigerio, M. Breda, 2004 .

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LC-MS/MS.

L. Miranda, B. Sasu, M. Rose, 2009, Journal of pharmacological and toxicological methods.

Assessment of normal and tumor tissue uptake of MAG-CPT, a polymer-bound prodrug of camptothecin, in patients undergoing elective surgery for colorectal carcinoma

M. Rocchetti, P. Nygren, N. Sarapa, 2003, Cancer Chemotherapy and Pharmacology.

Validation of a method for the determination of AMG 579 in cerebrospinal fluid with a focus on sample collection procedures for clinical trials.

M. Rose, C. James, Savannah J. Kerr, 2015, Journal of pharmaceutical and biomedical analysis.

A rapid method for the determination of plasma mexiletine levels by gas chromatography.

H. Rogers, C. James, I. Bradbrook, 1977, British journal of clinical pharmacology.

Ifosfamide plasma clearance in relation to polymorphic debrisoquine oxidation

P. Philip, L. Lewis, H. Rogers, 2004, Cancer Chemotherapy and Pharmacology.

Pharmacokinetics of intravenous and oral sodium 2-mercaptoethane sulphonate (mesna) in normal subjects.

H. Rogers, C. James, T. Mant, 1987, British journal of clinical pharmacology.

Punching and Extraction Techniques for Dried Blood Spot Sample Analysis

C. James, P. Wong, 2014 .

Application of DBS sampling in combination with LC-MS/MS for pharmacokinetic evaluation of a compound with species-specific blood-to-plasma partitioning.

C. James, B. Stouch, Guifen Xu, 2012, Bioanalysis.

Application of automated serial blood sampling and dried blood spot technique with liquid chromatography-tandem mass spectrometry for pharmacokinetic studies in mice.

Christopher A. James, Philip Wong, Roger Pham, 2011, Journal of pharmaceutical and biomedical analysis.

Determination of debrisoquine metabolic ratio from hourly urine collections in healthy volunteers.

P. Philip, H. Rogers, C. James, 1987, British journal of clinical pharmacology.

Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group

Eric Woolf, Philip Timmerman, Wenkui Li, 2014, The AAPS Journal.

Application of automated dried blood spot sampling and LC-MS/MS for pharmacokinetic studies of AMG 517 in rats.

C. James, Guifen Xu, M. Soto, 2011, Bioanalysis.

Bioanalytical method development and validation for the determination of glycine in human cerebrospinal fluid by ion-pair reversed-phase liquid chromatography-tandem mass spectrometry.

C. James, P. Wong, Jian Jiang, 2016, Journal of pharmaceutical and biomedical analysis.

Gender affects doxorubicin pharmacokinetics in patients with normal liver biochemistry

N. Dobbs, C. Twelves, R. Rubens, 2004, Cancer Chemotherapy and Pharmacology.

Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations: Considerations from the IQ Consortium Microsampling Working Group

T. Olah, P. Timmerman, E. Woolf, 2015, The AAPS Journal.

Determination of rosiglitazone and 5-hydroxy rosiglitazone in rat plasma using LC-HRMS by direct and indirect quantitative analysis: a new approach for metabolite quantification.

C. James, P. Wong, Jian Jiang, 2013, Bioanalysis.

Doxorubicin pharmacokinetics: the effect of abnormal liver biochemistry tests

N. Dobbs, C. Twelves, R. Rubens, 1998, Cancer Chemotherapy and Pharmacology.

Simultaneous Analysis of Multiple Monoclonal Antibody Biotherapeutics by LC-MS/MS Method in Rat Plasma Following Cassette-Dosing

Jean W. Lee, C. James, H. Salimi-Moosavi, 2013, The AAPS Journal.

Estimation of mesna and dimesna in plasma and urine by high-performance liquid chromatography with electrochemical detection.

H. Rogers, C. James, 1986, Journal of chromatography.

Procedural elements involved in maintaining bioanalytical data integrity for good laboratory practices studies and regulated clinical studies

Howard M. Hill, Christopher A. James, C. James, 2007, The AAPS Journal.

Effect of cimetidine on oral absorption of ampicillin and cotrimoxazole.

H. Rogers, C. James, I. Bradbrook, 1980, Journal of Antimicrobial Chemotherapy.

Quantitation of SU1 1248, an oral multi-target tyrosine kinase inhibitor, and its metabolite in monkey tissues by liquid chromatograph with tandem mass spectrometry following semi-automated liquid-liquid extraction.

C. James, C. Ye, Q. Zhang, 2004, Journal of chromatography. A.

Bioanalytical method validation: a risk-based approach?

C. James, C A James, M Breda, 2004, Journal of pharmaceutical and biomedical analysis.

Determination of PNU-248686A, a novel matrix metalloproteinase inhibitor, in human plasma by liquid chromatography-tandem mass spectrometry, following protein precipitation in the 96-well plate format.

C. James, V. Cenacchi, E. Frigerio, 2003, Journal of chromatography. A.