M. Simons

发表

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

C. Bergmann, M. Hennerici, K. Beyreuther, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons

B. Strooper, B. de Strooper, G. Multhaup, 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The beta‐amyloid domain is essential for axonal sorting of amyloid precursor protein.

C. Masters, B. de Strooper, G. Multhaup, 1996, The EMBO journal.

Cholesterol and Alzheimer’s disease

J. Dichgans, J. Schulz, P. Keller, 2001, Neurology.

Two‐dimensional gel mapping of the processing of the human amyloid precursor protein in rat hippocampal neurons

K. Beyreuther, P. Tienari, C. Dotti, 1995, FEBS letters.

Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons.

C. Masters, G. Multhaup, K. Beyreuther, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.

J. Schulz, M. Weller, G. Robertson, 1999, Journal of neurochemistry.

Cholesterol and Alzheimer’s disease: Is there a link?

J. Dichgans, J. Schulz, P. Keller, 2001 .

The 3-amyloid domainisessential foraxonalsorting ofamyloid precursorprotein

A. Weidemann, T. Hartmann, E. Ikonen, 1996 .

Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease.

C. Masters, B. de Strooper, K. Beyreuther, 1996, Cold Spring Harbor symposia on quantitative biology.

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo.

M. Hennerici, K. Beyreuther, H. Runz, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.

B. Strooper, B. de Strooper, K. Beyreuther, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Adenovirus‐Mediated Gene Transfer of Inhibitors of Apoptosis Proteins Delays Apoptosis in Cerebellar Granule Neurons

G. Robertson, T. Klockgether, R. Korneluk, 1999 .

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26‐week randomized, placebo‐controlled, double‐blind trial

J. Dichgans, K. Beyreuther, T. Hartmann, 2002, Annals of neurology.

Production of intracellular amyloid‐containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence.

B. de Strooper, G. Multhaup, K. Beyreuther, 1995, The EMBO journal.

Cholesterol depletion reduces aggregation of amyloid-beta peptide in hippocampal neurons

J. Schulz, W. Schulz-Schaeffer, A. Schneider, 2006, Neurobiology of Disease.

Intracellular routing of human amyloid protein precursor: Axonal delivery followed by transport to the dendrites

E. Ikonen, K. Beyreuther, E. Ikonen, 1995, Journal of neuroscience research.

Nutrient signaling pathways regulate amyloid clearance and synaptic loss in Alzheimer’s disease

R. Nitsch, T. Spires-Jones, P. Schulz, 2020, bioRxiv.

Exogenous administration of gangliosides displaces GPI-anchored proteins from lipid microdomains in living cells.

M. Masserini, J. Schulz, T. Kurzchalia, 1999, Molecular biology of the cell.